解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:INTRODUCTION:Infection-related glomerulonephritis (IRGN) is an example of immune-mediated glomerular injury, with changing profile over the years. We analyzed the clinicopathological profile of IRGN from a single center. MATERIALS AND METHODS:Adult renal biopsies between July 2018 and January 2020 were screened, and b...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN110246
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the predictors of renal outcomes in crescentic and mixed class of ANCA-associated glomerulonephritis. MATERIALS AND METHODS:We systematically reviewed the medical records of patients with ANCA-associated glomerulonephritis admitted to our hospital from December 2008 ...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN110221
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVE:Electron microscopy (EM) was used to observe the deposition and ultrastructural characteristics of amyloids in abdominal adipose tissue, which provided a reliable basis for pathological diagnosis of systemic amyloidosis. MATERIALS AND METHODS:42 patients with established amyloidosis and 8 controls underwent ...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN110320
更新日期:2021-01-12 00:00:00
abstract:BACKGROUND:In December 2019, the 2019 novel coronavirus disease (COVID-19) caused by SARS-CoV-2 emerged in China and now has spread to many countries. Limited data are available for hemodialysis patients with COVID-19. CASE PRESENTATION:We report a 66-year-old man with confirmed COVID-19 and parainfluenza virus infect...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN110164
更新日期:2020-10-01 00:00:00
abstract:AIMS:Medicinal plants contain many active constituents that can cause adverse effects on kidneys that are often unrecognized. The aim of our work was to study the association between the regular use of medicinal plants and the risk of chronic renal failure in hospitalized patients in four departments of Mohammed VI Uni...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN110105
更新日期:2020-09-01 00:00:00
abstract:AIM:Hypertension is a complex condition, and it is difficult to know whether inflammation is a cause or an effect. Information on the association between MRP-8/14 (myeloid-related protein) and hypertension is limited. In this study, we aimed to examine the relationship of MRP-8/14 with carotid intima-media thickness (C...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN110008
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:The predictive value of Doppler-based renal resistive index (RRI) for acute kidney injury (AKI) has not been fully elucidated. The present meta-analysis was carried out to disclose the correlation between AKI and RRI, and to investigate the predictive value of RRI for the onset of AKI and its recovery. MATE...
journal_title:Clinical nephrology
pub_type: 杂志文章,meta分析
doi:10.5414/CN109979
更新日期:2020-04-01 00:00:00
abstract:AIM:To evaluate the association between kidney dysfunction and cardiovascular disease (CVD) events in a middle-aged and elderly population in China. MATERIALS AND METHODS:In July 2009, a baseline survey of health status was performed in adults aged 55 years and older from Beijing, China. Occurrence of CVD events and m...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109712
更新日期:2020-03-01 00:00:00
abstract::The costs involved in the management of end-stage renal disease (ESRD) patients are overwhelming the healthcare commitments of countries worldwide and even more so in resource-limited settings. Some countries have intelligently managed to implement universal healthcare coverage for their citizens. Many others, unable ...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CNP92S116
更新日期:2020-01-01 00:00:00
abstract::Acute kidney injury (AKI) is prevalent and is associated with high morbidity and mortality globally. The epidemiology differs remarkably between developing and developed economies. Infections, diarrheal illnesses, obstetric causes and nephrotoxins are very rampant in the tropics. Even though the etiologies are differe...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CNP92S102
更新日期:2020-01-01 00:00:00
abstract::Hypertension is a common finding in patients with chronic kidney disease (CKD) and it is associated with kidney disease progression. Hypertensive nephropathy is a diagnosis, mostly based on clinical suspicion and defines many cases of CKD of unknown etiology. The risk of progression of hypertension-attributed nephropa...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CNP92S118
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Various studies have demonstrated that interleukin-6 (IL-6) activates the central magnocellular arginine vasopressin (AVP)-secreting neurons in the brain to produce non-osmotic, non-volume-mediated increases in AVP. The most common toxicity of CD19+ chimeric antigen receptor (CAR) T-cells is cytokine release...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109872
更新日期:2020-01-01 00:00:00
abstract::Bartter syndrome (BS), a rare autosomal recessive disorder affecting renal tubular potassium handling, is characterized by hypokalemia, metabolic alkalosis, and renal salt wasting. In this report, we describe an adult patient with longstanding clinical symptoms of fatigue, polyuria, polydipsia, mental retardation, and...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109784
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Increased carotid intima media thickness (cIMT) is one of the early changes seen in chronic kidney disease (CKD) associated cardiovascular disease. This study aimed to determine cIMT measurements and its association with cardiovascular risk factors, including fibroblast growth factor-23 (FGF-23) and fetuin-A...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109791
更新日期:2019-11-01 00:00:00
abstract::COL4A5 gene mutations are known as the cause of Alport syndrome (AS), which typically manifests with hematuria, progressive renal failure, sensorineural hearing loss, and ocular abnormalities. Here we report a case of a 20-year-old male patient presenting with nephrotic syndrome who was diagnosed as having AS with foc...
journal_title:Clinical nephrology
pub_type: 杂志文章,评审
doi:10.5414/CN109737
更新日期:2019-08-01 00:00:00
abstract::Most patients in the United States initiate hemodialysis (HD) with a central venous catheter (CVC) despite a significantly increased morbidity and mortality associated with their use. Reasons for CVC-based starts have been identified, but the relative frequency of each is less clear. The aim of this retrospective char...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109396
更新日期:2019-07-01 00:00:00
abstract:AIMS:We attempted to classify 115 consecutive nonedematous hyponatremic patients according to their history and saline responsiveness. We hereby describe 6 out of them presenting a transient renal salt wasting (TRSW) state of unknown origin. MATERIALS AND METHODS:Six patients with an initial SNa of 126 ± 3 mEq/L were ...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109472
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Donor organ quality is a key determinant of graft outcomes in deceased donor kidney transplantation (DDKT). The predictive values of baseline histopathology and several clinical scoring systems for long-term graft outcomes have been evaluated, but the results remain controversial. MATERIALS AND METHODS:We s...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109639
更新日期:2019-06-01 00:00:00
abstract:AIMS:Endothelin-1 (ET-1) is associated with the pathophysiology of autosomal dominant polycystic kidney disease (ADPKD) via cyst progression. Elevated concentrations of ET-1 in ADPKD correlate with many phenotypic changes in the kidney such as renal cyst development, interstitial fibrosis, and glomerulosclerosis. In ad...
journal_title:Clinical nephrology
pub_type: 杂志文章,评审
doi:10.5414/CN109598
更新日期:2019-06-01 00:00:00
abstract:INTRODUCTION:Renal osteodystrophy (ROD) develops early in chronic kidney disease (CKD) and progresses with loss of kidney function. While intact parathyroid hormone (PTH), 1,25-dihydroxyvitamin D3 (1,25D), and fibroblast growth factor-23 (FGF-23) levels are usually considered the primary abnormalities in ROD developmen...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109650
更新日期:2019-04-01 00:00:00
abstract:AIMS:To investigate the clinicopathological features and outcomes of adefovir dipivoxil (ADV)-related renal impairment in Chinese patients. MATERIALS AND METHODS:Clinical, pathological, and follow-up data from 15 patients with ADV-related renal impairment were studied. Proximal renal tubular dysfunction (PRTD) was def...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109574
更新日期:2019-03-01 00:00:00
abstract::Systemic capillary leak syndrome (SCLS) is a disorder characterized by increased vascular permeability with intermittent acute episodes of profound capillary leak that may result in hypotension or shock. A rarely described chronic form of SCLS (cSCLS) presents as refractory edema, with pleural and/or pericardial effus...
journal_title:Clinical nephrology
pub_type: 杂志文章,评审
doi:10.5414/CN109467
更新日期:2019-01-01 00:00:00
abstract::The etiology of pulmonary renal syndrome can be broadly divided into infectious and autoimmune (predominantly ANCA vasculitis). The importance of timely differentiating between them stems from the deleterious effects of their respective treatment if misdiagnosed. Serology and tissue evaluation by pathology are employe...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109495
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:There is paucity of data on the outcomes of in-hospital cardiopulmonary resuscitation (CPR) in patients with acute kidney injury (AKI). We analyzed the impact of acute kidney injury on in-hospital CPR-related outcomes. MATERIALS AND METHODS:We analyzed data from Nationwide Inpatient Sample (NIS 2005 - 2011)...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109496
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Standard protocol-based approaches to erythropoiesis stimulating agent (ESA) dosing in anemia management of end-stage renal disease (ESRD) fail to address the inter-individual variability in patient's response to ESA. We conducted a single-center quality improvement project to investigate the long-term perfo...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109499
更新日期:2018-10-01 00:00:00
abstract:INTRODUCTION:To evaluate nephrostomy catheter displacement, we assessed the cumulative nephrostomy catheter displacement rate in patients with percutaneous nephrostomy and compared the nephrostomy displacement rates between pigtail and balloon catheters. MATERIALS AND METHODS:Between 2003 and 2011, 87 patients who und...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109294
更新日期:2018-08-01 00:00:00
abstract:INTRODUCTION:Methanol intoxication is an infrequent cause of poisoning in the United Sates. It can present with prominent stroke-like features and acute kidney injury. Despite the life-threatening nature of this condition, it is poorly identified by clinicians. We aim to present a case of rapidly progressive mental dec...
journal_title:Clinical nephrology
pub_type: 杂志文章,评审
doi:10.5414/CN109494
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:To assess the performance of the full age spectrum (FAS) equation in comparison to other equations in subjects with chronic kidney disease (CKD) for the first time in China. MATERIALS AND METHODS:The measured glomerular filtration rate (mGFR) obtained by the 99mTc-diethylenetriamine pentaacetic ac...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109256
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Antithyroid drugs such as propylthiouracil and methimazole have been reported to cause antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), but little is known about long-term outcomes. MATERIALS AND METHODS:We identified AAV patients who underwent renal biopsy and retrospectively assesse...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109364
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND AND AIMS:Recent clinical evidence demonstrates that chronic low-dose mineralocorticoid receptor antagonists (MRA), when added to optimal treatment, result in reductions in cardiovascular mortality. However, continuation of MRAs before cardiac surgery in patients with CKD has never been evaluated and its pote...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109236
更新日期:2018-03-01 00:00:00
abstract::Oxaliplatin is a platinum compound commonly used in the treatment of advanced colorectal cancer. This report describes two patients who had received repetitive combination chemotherapy including oxaliplatin for the treatment of metastatic colon cancer and who visited the emergency department with acute kidney injury s...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109131
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Recent data suggest that the use of medium cut-off (MCO) dialyzers in hemodialysis (HD) promotes greater clearance and reduction ratio (RR) for myoglobin and other large-sized molecules than on-line hemodiafiltration (ol-HDF), but its effects on β2-microglobulin are not clear. We compared RR and clearances o...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109133
更新日期:2018-01-01 00:00:00
abstract:AIM:This study aimed to assess the association of single-nucleotide polymorphism (SNP) of FKBP5 with response to steroids in children with primary nephrotic syndrome (NS). MATERIALS AND METHODS:A total of 66 primary NS patients (cases) and 68 healthy individuals (controls) were enrolled in this study. The FKBP5 polymo...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109126
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Shifting from a short-term catheter to a long-term one is done either by removing the old catheter and placing a new long-term one via fresh new puncture site, or by replacing the old catheter with a long-term one over a guidewire. AIM:We aimed to describe our technique in changing a temporary line to a lon...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN108943
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:Given regulatory and reimbursement changes in anemia management, we examined hemoglobin variability in a contemporary cohort of maintenance hemodialysis patients. MATERIALS AND METHODS:The study population included > 200,000 hemodialysis patients with Medicare parts A and B as primary payer on October 1, 20...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109031
更新日期:2017-11-01 00:00:00
abstract::A 37-year-old Japanese man with a serum creatinine level of 2.5 mg/dL and hepatomegaly was admitted to our hospital for investigation of renal failure. Magnetic resonance imaging (MRI) showed hepatomegaly with small cystic lesions that had high signal intensity on T2-weighted images. There was no splenomegaly, and the...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN109179
更新日期:2017-11-01 00:00:00
abstract::Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare but potentially fatal adverse drug reaction with variable renal involvement. We report the case of a man who presented with allopurinol-induced DRESS and acute kidney injury (AKI) requiring hemodialysis. Kidney biopsy revealed eosinophilic tubuloi...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN108966
更新日期:2017-06-01 00:00:00
abstract:AIMS:Transport characteristics of phosphorus are different from other small solutes that are evaluated in routine peritoneal equilibration test (PET) in peritoneal dialysis (PD) patients. We aimed to evaluate peritoneal phosphorus clearance and permeability, and their relationship with peritoneal membrane transport typ...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CN108954
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:In a healthy individual, ammonia is converted to urea in the liver. Urea is then transported through the bloodstream and then excreted into the urine by the kidneys. In patients with chronic kidney disease (CKD), the accumulated urea is degraded by salivary urease into ammonia, which is then excreted by brea...
journal_title:Clinical nephrology
pub_type: 杂志文章
doi:10.5414/CNP88FX04
更新日期:2017-01-01 00:00:00
abstract:AIM:To assess the possibility of using filtered plasma instead of postfilter ionized calcium (iCa) for the assessment of anticoagulation in plasma exchange (PE) with citrate anticoagulation. METHODS:140 PE treatments were performed using either 4% or 15% citrate at a comparable dose. Paired samples of postfilter blood...
journal_title:Clinical nephrology
pub_type: 杂志文章,随机对照试验
doi:10.5414/CNP88FX13
更新日期:2017-01-01 00:00:00