解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Parathyroid carcinoma is a very rare disease that is accompanied by a poor prognosis. Diagnosis is based on laboratory tests (calcium, parathyroid hormone), sonography, and scintigraphy. Complete surgical resection is the treatment of choice. Adjuvant therapy is controversial. The lack of treatment guidelines and expe...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-020-00986-y
更新日期:2021-01-18 00:00:00
abstract::Tumoral lesions in the head and neck region represent a diagnostic and therapeutic challenge in otorhinolaryngologic routine. High-resolution ultrasound is usually able to guide diagnosis. Nevertheless, a definite differentiation between benign and malignant lesions can only be achieved by tissue biopsy. The various o...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-020-00981-3
更新日期:2021-01-08 00:00:00
abstract:INTRODUCTION:After cochlear implantation, auditory and speech training is usually necessary. Up until now, this has been performed on an out- or inpatient basis in direct contact with a therapist. Due to technical advances but also particularly because of an increasing use of digital media and a desire for mobility and...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-020-00914-0
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Immunoglobulin (Ig)G4-related disease is classified as an immune-mediated disease. The etiology of this condition has not been explained to date. Manifestations of the disease are diverse, and simultaneous involvement of multiple organs is not unusual. CASE REPORT:We report the case of a patient referred to...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-019-00798-9
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Digitalization has become a part of everyday life and digital applications offer an opportunity to promote health. In Germany, hearing rehabilitation after cochlear implantation (CI) typically takes place in specialized audiology centers. However, a variety of new auditory training programs have been develop...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-020-00898-x
更新日期:2020-11-01 00:00:00
abstract::External otitis is one of the most common infections in the head and neck region, as about 10% of all people suffer from it at least once during their life. It is an infection of the cutis and subcutis of the outer ear canal caused by bacteria, viruses, and fungus as well as allergens or degenerative toxic substances....
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-020-00952-8
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:In contrast to alcohol- and nicotine-induced head and neck tumors, human papillomavirus (HPV)-positive oropharyngeal carcinoma rather affects younger patients, and the incidence of this entity is continuously increasing. Due to the significantly better prognosis of HPV-positive oropharyngeal carcinoma, vario...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-020-00955-5
更新日期:2020-10-13 00:00:00
abstract:INTRODUCTION:Hearing rehabilitation with cochlear implants has attracted increasing interest also for patients with cochleovestibular schwannoma. The authors report their experience with the surgical management of tumors with rare transmodiolar or transmacular extension and outcomes after cochlear implantation (CI). M...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-020-00919-9
更新日期:2020-10-12 00:00:00
abstract:BACKGROUND:Epistaxis is a common symptom in the medical practice. It is associated with various comorbidities and the use of medications, especially anticoagulants. Despite the high lifetime prevalence, there is limited data on prevalence and possible risk factors. METHODS:The study examines epistaxis care in a large ...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-020-00940-y
更新日期:2020-09-14 00:00:00
abstract:BACKGROUND:Patulous Eustachian tube (ET) dysfunction can impair quality of life (QOL) due to autophony, pressure sensation, and an altered impression of sound. In cases of nonspecific complaints the diagnosis of patulous ET can be difficult, and its distinction from chronic obstructive ET dysfunction is particularly ch...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-020-00931-z
更新日期:2020-09-03 00:00:00
abstract::The incidence of human papillomavirus (HPV)-positive oropharyngeal carcinomas is increasing worldwide. Due to a markedly different response to treatment compared to HPV-negative oropharyngeal carcinomas, determining the ideal therapeutic approach can be challenging. Particularly in never-smokers, HPV-positive orophary...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-020-00900-6
更新日期:2020-09-01 00:00:00
abstract::A rare finding of primary cutaneous CD4+ small to medium-sized T‑cell lymphoma (SMPTCL) in a fifteen-year-old patient is reported. This is a rare tumor entity for which there is currently no standardized treatment recommendation. At the interdisciplinary tumor board, the decision was made to resect the tumor and recon...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-020-00912-2
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Improvement of speech perception in quiet is an important goal of hearing aid provision. In practice, results are highly variable. The aim of this study was to investigate the relationship between type and extent of hearing loss (audiogram type), maximum word recognition score, and aided speech perception. ...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-020-00843-y
更新日期:2020-08-01 00:00:00
abstract::Although the history of intraoperative neuromonitoring (IONM) dates back to the 19th century, the method did not evolve further than the mere differentiation of nerves until recently. Only the development of continuous IONM (cIONM) has allowed for non-stop analysis of excitation amplitude and latency during surgical p...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-020-00824-1
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:The question of the "true" function of the maxillary sinus and the paranasal sinuses (PS) has been a controversial issue in the literature for decades, leading to many discussions and speculations. OBJECTIVE:This review briefly summarizes various theories on the possible physiology and functions of the maxi...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-020-00869-2
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:A new German speech audiometry test was developed using 26 nouns that are most likely part of the lexicon of 2‑year-old children. The test was a picture-pointing task using a four-alternative non-forced choice method. MATERIALS AND METHODS:In total, 179 children aged 2 years 11 months to 6 years 9 months wer...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-019-00788-x
更新日期:2020-07-01 00:00:00
abstract::Ectopic thyroid gland tissue can occur either as the only detectable thyroid gland tissue or in addition to a normotopic thyroid gland. After a total thyroidectomy thyroid-stimulating hormone (TSH) can induce a compensatory volume increase of previously asymptomatic ectopic tissue. This hyperplastic ectopic tissue can...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-019-00754-7
更新日期:2020-06-01 00:00:00
abstract::Unilateral vocal fold palsy is a frequent cause of hoarseness. In the presence of glottis closure insufficiency, the effectiveness of conservative voice therapy is often limited and phonosurgery may be indicated. Injection laryngoplasty is effective for correction of insufficiency. Early intervention during the first ...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-020-00863-8
更新日期:2020-06-01 00:00:00
abstract::Due to late diagnosis and poor treatment response, advanced head and neck squamous cell carcinoma (HNSCC) belongs to the tumor diseases with highest mortality worldwide. Although many biomarkers have been investigated over the past years, none have yet become established in clinical practice. There is thus an urgent n...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-019-00806-y
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Tongue motion patterns (TMP) can influence the outcome of upper airway stimulation (UAS) in the treatment of obstructive sleep apnea (OSA). As a postoperative control, the cuff position of the stimulation lead is monitored via X‑ray imaging. A multidimensional X‑ray assessment system was established and the ...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-019-0717-4
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Logatomes, nonsensical combinations of consonants and vowels, are suitable for a precise capture and analysis of individual phonemes as fundamental modules of speech in audiometric diagnostics. OBJECTIVE:The aim of this prospective study was to capture the audiometric characteristics of a closed-set logatom...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-019-00771-6
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Patients with single-sided deafness (SSD) are limited by their asymmetric hearing in various areas of everyday life. OBJECTIVE:The aim of this investigation was to perform an age-correlated comparison of the hearing threshold of the better ear of SSD patients with a normal-hearing (NH) reference cohort. In ...
journal_title:HNO
pub_type: 杂志文章,多中心研究
doi:10.1007/s00106-019-00739-6
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Due to their comparatively low incidence, salivary gland carcinomas have only been the subject of isolated clinical studies in recent years. In addition, surgery with/without adjuvant radiotherapy is considered standard treatment. Systemic therapies have received little attention and are only used for advanc...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-019-00760-9
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:The contributions presented at this year's ASCO conference on treatment of recurrent or metastatic head and neck squamous cell carcinoma (R/M-HNSCC) focused on systemic therapies, as in recent years. Two phase III studies-TPExtreme and Keynote-048-are expected to change clinical practice in first-line treatm...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-019-00773-4
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Primary immunodeficiency is a rare disease of humoral and cellular immune defense, which can lead to severe and recurrent infections of different organs. The diagnosis of this disease is often difficult, and its early identification is necessary for adequate treatment and control. OBJECTIVE:This study aimed...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-019-0683-x
更新日期:2019-11-01 00:00:00
abstract::Diagnostic and therapeutic approaches to the petrous apex involve sub-/transtemporal, retrosigmoidal, infratemporal and-lesser invasive-e. g. infracochlear, infralabyrinthine or under favourable anatomic conditions, transsphenoidal surgical pathways. For diagnostic purposes, minimally invasive approaches should be pre...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-019-0687-6
更新日期:2019-10-01 00:00:00
abstract::We were able to demonstrate that simultaneous treatment of a patient with a neuromodulation device for deep brain stimulation (DBS) or occipital nerve stimulation (ONS) plus a cochlear implant is a possible treatment option, and that both systems are able to work within their specifications without interference from e...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-019-00731-0
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:In addition to basic ophthalmologic diagnostic workup, different radiologic procedures can be performed for assessment of nasolacrimal duct obstruction. However, no gold standard imaging technique has yet been established. Using the results of the present study, the advantages of helical CT-dacryocystography...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-019-0669-8
更新日期:2019-08-01 00:00:00
abstract::The current article is an experience report on the establishment of an ENT clinic in Asmara/Eritrea and the organization of regular work stays for the further education of local colleagues. Objectives of the project are content and structural support for self-help and thus achievement of sustainable development aid, w...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-019-0690-y
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Intense endocytic activity at the apex of outer hair cells (OHCs)-the electromechanical cells of the cochlea-has been demonstrated using the vital plasma-membrane marker FM1-43 and confocal laser-scanning microscopy. Vesicular traffic toward the cell nucleus to distinct locations of the endoplasmic reticulum...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-019-0674-y
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:There is no established method to objectively measure the moisture status of nasal mucosa. In a pilot study it was shown that a nasal Schirmer test is a possible method. The aim of the current study was to check whether the nasal Schirmer test is suitable to define moisture status in cases with an expected p...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-019-0627-5
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Digitalization is significantly changing the entire healthcare sector. Hospitals must act now in order to remain competitive. OBJECTIVE:To assess which approaches exist for digitalization along the treatment chain and how digitalization can be strategically implemented. MATERIALS AND METHODS:An analysis of...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-019-0655-1
更新日期:2019-05-01 00:00:00
abstract:: ...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-018-0565-7
更新日期:2019-02-01 00:00:00
abstract::The aim of classical surgical correction for nasal breathing impairment is to harmonically extend the physiological space in the nose by an operation of the nasal septum and inferior nasal turbinate. In this way the airflow character should be maintained and the mucosa protected in order not to endanger the respirator...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-018-0587-1
更新日期:2019-02-01 00:00:00
abstract::Tinnitus is a common symptom of unclear origin that can be multifactorially caused and maintained. It is frequently, but not inevitably, associated with hearing loss. Emotional distress and maladaptive coping strategies - that are associated with or amplified by the tinnitus percept - pose key targets for psychologica...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-019-0609-7
更新日期:2019-02-01 00:00:00
abstract::Neck dissection (ND) is an essential component of treatment in head and neck squamous cell carcinoma (HNSCC). The extent of ND depends on primary tumor location and T and N stage. Trials have demonstrated improved survival for cN+ status with therapeutic ND as well as for cN0 status with selective ND if the primary ha...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-018-0601-7
更新日期:2019-01-01 00:00:00
abstract:: ...
journal_title:HNO
pub_type: 社论
doi:10.1007/s00106-018-0579-1
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:In the case of trauma to the midface, an accompanying fracture of the orbit is common because to the anatomical conditions (bony buttresses of the midface). Etiology varies according to locoregional conditions. MATERIALS AND METHODS:An overview of orbital traumatology including diagnostic procedures, sympto...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-018-0525-2
更新日期:2018-10-01 00:00:00
abstract::Swallowing is a dynamic process that requires more than 30 muscles in the recruitment/coordination of the lips, tongue, palate, pharynx, larynx and esophagus. The eating and swallowing procedure is learned in sensitive or critical periods: when a certain degree of maturation has been achieved, the appropriate stimulus...
journal_title:HNO
pub_type: 杂志文章,评审
doi:10.1007/s00106-017-0388-y
更新日期:2018-07-01 00:00:00
abstract::Compared to other countries, the prevalence of speech-language disorders among children and also the intervention frequency appear to be much higher in Germany. Since otorhinolaryngologists often initiate speech-language interventions, the first part of this review systematically outlines the guideline-conform diagnos...
journal_title:HNO
pub_type: 杂志文章
doi:10.1007/s00106-018-0509-2
更新日期:2018-06-01 00:00:00