abstract：:The novel coronavirus disease-2019 (Covid-19) public health emergency has caused enormous loss around the world. This pandemic is a concrete example of the existing gap between availability of advanced diagnostics and current need for cost-effective methodology. The advent of the loop-mediated isothermal amplification...

journal_title：Reviews in medical virology

authors： Chaouch M

更新日期：2021-01-21 00:00:00

abstract：:Dengue disease encompasses various clinical manifestations including dengue fever (DF) and dengue hemorrhagic fever (DHF). In this article, we aimed to systematically review and analyze the association between different blood groups and severity of dengue. We searched nine databases for eligible papers reporting preva...

journal_title：Reviews in medical virology

authors： Hashan MR,Ghozy S,El-Qushayri AE,Pial RH,Hossain MA,Al Kibria GM

更新日期：2021-01-01 00:00:00

abstract：:Of all the nutrients, vitamin A has been the most extensively evaluated for its impact on immunity. There are three main forms of vitamin A, retinol, retinal and retinoic acid (RA) with the latter being most biologically active and all-trans-RA (ATRA) its main derivative. Vitamin A is a key regulator of the functions ...

journal_title：Reviews in medical virology

authors： Midha IK,Kumar N,Kumar A,Madan T

更新日期：2020-12-31 00:00:00

abstract：:Type B coxsackieviruses (CV-B) frequently infect the central nervous system (CNS) causing neurological diseases notably meningitis and encephalitis. These infections occur principally among newborns and children. Epidemiological studies of patients with nervous system disorders demonstrate the presence of infectious v...

journal_title：Reviews in medical virology

authors： Jmii H,Fisson S,Aouni M,Jaidane H

更新日期：2020-11-07 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1), the virus that causes AIDS (acquired immunodeficiency syndrome), is a major global public health issue. Although the advent of combined antiretroviral therapy (ART) has made significant progress in inhibiting HIV replication in patients, HIV-infected cells remain the princi...

journal_title：Reviews in medical virology

authors： Namdari H,Rezaei F,Teymoori-Rad M,Mortezagholi S,Sadeghi A,Akbari A

更新日期：2020-11-01 00:00:00

abstract：:Remdesivir is an antiviral agent that has shown broad-spectrum activity, including against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clinical trials investigating the role of remdesivir in coronavirus disease 2019 (Covid-19) reported conflicting results. This study aimed to systematically review th...

journal_title：Reviews in medical virology

authors： Elsawah HK,Elsokary MA,Abdallah MS,ElShafie AH

更新日期：2020-10-31 00:00:00

abstract：:The collection of nasopharyngeal swabs to test for the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an invasive technique with implications for patients and clinicians. Alternative clinical specimens from the upper respiratory tract may offer benefits in terms of collection, comfort and ...

journal_title：Reviews in medical virology

authors： Comber L,Walsh KA,Jordan K,O'Brien KK,Clyne B,Teljeur C,Drummond L,Carty PG,De Gascun CF,Smith SM,Harrington P,Ryan M,O'Neill M

更新日期：2020-10-22 00:00:00

abstract：:The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel human respiratory viral infection that has rapidly progressed into a pandemic, causing significant morbidity and mortality. Blood clotting disorders and acute respiratory failure have surfaced as the major complications among the severe cases ...

journal_title：Reviews in medical virology

authors： Pujhari S,Paul S,Ahluwalia J,Rasgon JL

更新日期：2020-10-06 00:00:00

abstract：:BK polyomavirus (BKPyV or BKV) is a non-enveloped, circular double-stranded DNA virus that may exceed 80% seroprevalence in adults. BKV infection typically occurs during childhood, and the majority of adults are latently infected. While BKV infection is rarely associated with clinical disease in most individuals, in i...

journal_title：Reviews in medical virology

authors： Blackard JT,Davies SM,Laskin BL

更新日期：2020-07-01 00:00:00

abstract：AUTHOR CONTRIBUTION:FN performed the literature review and wrote the manuscript; STZ coauthored, edited, and reviewed the manuscript. ABSTRACT:Treatment response in Hepatitis C virus (HCV) has generated varied effects in patients. Recently, nonresponsive and relapse patients related to host and genotype variabilities ...

journal_title：Reviews in medical virology

authors： Fadl N,Salem TZ

更新日期：2020-07-01 00:00:00

abstract：:There is a growing appreciation that the regulation of the melatonergic pathways, both pineal and systemic, may be an important aspect in how viruses drive the cellular changes that underpin their control of cellular function. We review the melatonergic pathway role in viral infections, emphasizing influenza and covid...

journal_title：Reviews in medical virology

authors： Anderson G,Reiter RJ

更新日期：2020-05-01 00:00:00

abstract：:Bacteriophages or phages, being the most abundant entities on earth, represent a potential solution to a diverse range of problems. Phages are successful antibacterial agents whose use in therapeutics was hindered by the discovery of antibiotics. Eventually, because of the development and spread of antibiotic resistan...

journal_title：Reviews in medical virology

authors： Rehman S,Ali Z,Khan M,Bostan N,Naseem S

更新日期：2019-07-01 00:00:00

abstract：:Although epidemiological and molecular epidemiological (serotype, genotype, and lineage information) data are available for several major cities in Indonesia, there is yet to be a comprehensive national study of dengue in Indonesia over time. This study was conducted to provide a comprehensive epidemiology of circulat...

journal_title：Reviews in medical virology

authors： Harapan H,Michie A,Yohan B,Shu PY,Mudatsir M,Sasmono RT,Imrie A

更新日期：2019-07-01 00:00:00

abstract：:Respiratory infections, especially those of the lower respiratory tract, remain a foremost cause of mortality and morbidity of children greater than 5 years in developing countries including Pakistan. Ignoring these acute-level infections may lead to complications. Particularly in Pakistan, respiratory infections acco...

journal_title：Reviews in medical virology

authors： Naz R,Gul A,Javed U,Urooj A,Amin S,Fatima Z

更新日期：2019-03-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) infection is the most common cause of bronchiolitis and pneumonia in the pediatric population worldwide. The immunopathology of RSV infection varies considerably and severe disease occurs only in a minority of the population. There are many factors (host, viral, and environmental) tha...

journal_title：Reviews in medical virology

authors： Tahamtan A,Askari FS,Bont L,Salimi V

更新日期：2019-03-01 00:00:00

abstract：:Tat (transactivator of transcription) regulates transcription from the HIV provirus. It plays a crucial role in disease progression, supporting efficient replication of the viral genome. Tat also modulates many functions in the host genome via its interaction with chromatin and proteins. Many of the functions of Tat a...

journal_title：Reviews in medical virology

authors： Kurnaeva MA,Sheval EV,Musinova YR,Vassetzky YS

更新日期：2019-03-01 00:00:00

abstract：:Novel therapeutic options are urgently needed to improve the global treatment of viral infections. Tripartite motif (TRIM) family proteins are involved in various biological and cellular functions including differentiation, development, proliferation, oncogenesis, innate immunity, and viral autophagy. Various TRIM pro...

journal_title：Reviews in medical virology

authors： Khan R,Khan A,Ali A,Idrees M

更新日期：2019-03-01 00:00:00

abstract：:Maternofetal transmission of cytomegalovirus (CMV) is the most common infectious cause of congenital malformation in developed countries. Maternal infection often results from close contact with infected children, and this may occur in day care centres (DCCs). A systematic review of observational studies was conducted...

journal_title：Reviews in medical virology

authors： Zheng QY,Huynh KT,van Zuylen WJ,Craig ME,Rawlinson WD

更新日期：2019-01-01 00:00:00

abstract：:The alarming rise of morbidity and mortality caused by influenza pandemics and epidemics has drawn attention worldwide since the last few decades. This life-threatening problem necessitates the development of a safe and effective vaccine to protect against incoming pandemics. The currently available flu vaccines rely ...

journal_title：Reviews in medical virology

authors： Keshavarz M,Mirzaei H,Salemi M,Momeni F,Mousavi MJ,Sadeghalvad M,Arjeini Y,Solaymani-Mohammadi F,Sadri Nahand J,Namdari H,Mokhtari-Azad T,Rezaei F

更新日期：2019-01-01 00:00:00

abstract：:The orf virus (ORFV) is a zoonotic, epitheliotropic, DNA parapoxvirus that infects principally sheep and goats. Exposure of animals to the virus or immunization by an ORFV preparation can accentuate the severity of disease, which has provoked an interest in the underlying cellular, virological, and molecular mechanism...

journal_title：Reviews in medical virology

authors： Wang R,Wang Y,Liu F,Luo S

更新日期：2019-01-01 00:00:00

abstract：:Hepatitis E virus (HEV) is the leading cause of acute viral hepatitis worldwide and an emerging cause of chronic infection in immunocompromised patients. As with viral infections in general, immune responses are critical to determine the outcome of HEV infection. Accumulating studies in cell culture, animal models and...

journal_title：Reviews in medical virology

authors： Hakim MS,Ikram A,Zhou J,Wang W,Peppelenbosch MP,Pan Q

更新日期：2018-03-01 00:00:00

abstract：:Viral binding and entry into host cells for various viruses have been studied extensively, yielding a detailed understanding of the overall viral entry process. As cell entry is an essential and requisite process by which a virus initiates infection, it is an attractive target for therapeutic intervention. The advanta...

journal_title：Reviews in medical virology

authors： Kumar PKR

更新日期：2017-11-01 00:00:00

abstract：:Hepatitis E virus (HEV) is responsible for more than 50% of acute viral hepatitis cases in endemic countries. Approximately 2 billion individuals live in hepatitis E-endemic areas and, therefore, are at risk of infection. According to World Health Organization, HEV causes about 20.1 million infections and 70 000 death...

journal_title：Reviews in medical virology

authors： Pérez-Gracia MT,Suay-García B,Mateos-Lindemann ML

更新日期：2017-05-01 00:00:00

abstract：:Viruses are obligate parasites dependent on host cells for survival. Viral infection of a cell activates a panel of pattern recognition receptors that mediate antiviral host responses to inhibit viral replication and dissemination. Viruses have evolved mechanisms to evade and subvert this antiviral host response, incl...

journal_title：Reviews in medical virology

authors： van Zuylen WJ,Rawlinson WD,Ford CE

更新日期：2016-09-01 00:00:00

abstract：:Blood-borne viruses, such as hepatitis B virus, hepatitis C virus, human immunodeficiency virus, and the facultative blood-borne hepatitis E virus, are considered a major public health problem given that they are accountable for millions of deaths each year. Treatment options, including effective vaccine design, devel...

journal_title：Reviews in medical virology

authors： Pfaender S,von Hahn T,Steinmann J,Ciesek S,Steinmann E

更新日期：2016-09-01 00:00:00

abstract：:Viral replication and spreading are fundamental events in the viral life cycle, accounting for the assembly and egression of nascent virions, events that are directly associated with viral pathogenesis in target hosts. These processes occur in cellular compartments that are modified by specialized viral proteins, caus...

journal_title：Reviews in medical virology

authors： de Armas-Rillo L,Valera MS,Marrero-Hernández S,Valenzuela-Fernández A

更新日期：2016-05-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML) is a devastating and often fatal demyelinating disease of the central nervous system for which effective therapies are lacking. It is caused by the replication of polyomavirus JC (JCV) in the oligodendrocytes and astrocytes leading to their cytolytic death and loss of m...

journal_title：Reviews in medical virology

authors： White MK,Sariyer IK,Gordon J,Delbue S,Pietropaolo V,Berger JR,Khalili K

更新日期：2016-03-01 00:00:00

abstract：:The mosquito-borne flavivirus, Japanese encephalitis virus (JEV), is the leading cause of virus-induced encephalitis globally and a major public health concern of several countries in Southeast Asia, with the potential to become a global pathogen. The virus is neurotropic, and the disease ranges from mild fever to sev...

journal_title：Reviews in medical virology

authors： Nain M,Abdin MZ,Kalia M,Vrati S

更新日期：2016-03-01 00:00:00

abstract：:Hepatitis B virus (HBV) is one of the causative agents of hepatocellular carcinoma. The molecular mechanisms of tumorigenesis are complex. One of the host factors involved is apparently the long-lasting inflammatory reaction which accompanies chronic HBV infection. Although HBV lacks a typical viral oncogene, the HBx ...

journal_title：Reviews in medical virology

authors： Niller HH,Ay E,Banati F,Demcsák A,Takacs M,Minarovits J

更新日期：2016-01-01 00:00:00

abstract：:After the serendipitous discovery of HIV eradication in the "Berlin patient", interest has grown in curing HIV infection by replacing the patient's replication-competent blood cells with infection-resistant ones. At the same time, induced pluripotent stem cell technologies and genetic engineering have boosted cell the...

journal_title：Reviews in medical virology

authors： Focosi D,Maggi F,Ceccherini-Nelli L,Pistello M

更新日期：2015-05-01 00:00:00

abstract：:Enteroviruses and humans have long co-existed. Although recognized in ancient times, poliomyelitis and type 1 diabetes (T1D) were exceptionally rare and not epidemic, due in large part to poor sanitation and personal hygiene which resulted in repeated exposure to fecal-oral transmitted viruses and other infectious age...

journal_title：Reviews in medical virology

authors： Drescher KM,von Herrath M,Tracy S

更新日期：2015-01-01 00:00:00

abstract：:Chikungunya fever (CHIKF) caused by the mosquito-transmitted chikungunya virus (CHIKV) swept into international prominence from late 2005 as an epidemic of CHIKF spread around countries surrounding the Indian Ocean. Although significant advances have been made in understanding the pathobiology of CHIKF, numerous quest...

journal_title：Reviews in medical virology

authors： Smith DR

更新日期：2015-01-01 00:00:00

abstract：:Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) are two γ-herpesviruses identified in humans and are strongly associated with the development of malignancies. Murine γ-herpesvirus (MHV-68) is a naturally occurring rodent pathogen, representing a unique experimental model for dissecting γ-he...

journal_title：Reviews in medical virology

authors： Hu Z,Usherwood EJ

更新日期：2014-11-01 00:00:00

abstract：:The discovery of acyclovir (ACV), a nucleoside analogue, more than 30 years ago, represents a milestone in the management of HSV and VZV infections. The modest activity of ACV against CMV prompted the development of another nucleoside analogue, ganciclovir, for the management of systemic and organ-specific CMV disease...

journal_title：Reviews in medical virology

authors： Piret J,Boivin G

更新日期：2014-05-01 00:00:00

abstract：:Failure of antiretroviral therapy to eradicate HIV, even in individuals who suppress the virus to undetectable levels, is a consequence of persistent infection in latently infected cells and within anatomical reservoirs. Support for the notion that the lungs are distinct anatomical reservoirs of HIV comes from a spect...

journal_title：Reviews in medical virology

authors： Costiniuk CT,Jenabian MA

更新日期：2014-01-01 00:00:00

abstract：:The viruses able to affect the eye are taxonomically diverse, ranging from double-stranded DNA viruses, to single stranded RNA viruses, to retroviruses. Any part of the eye may be affected, frequently producing blepharitis, conjunctivitis, keratitis, uveitis, cataract and retinitis. The more common ocular viral infect...

journal_title：Reviews in medical virology

authors： Newman H,Gooding C

更新日期：2013-09-01 00:00:00

abstract：:Until 2006, BKPyV and JCPyV were the only known human polyomaviruses. A third polyomavirus, simian virus 40 whose natural host is the macaque was accidently introduced into man because of contaminated poliovirus vaccines, although there is epidemiological evidence that SV40 may be transmitted between man independently...

journal_title：Reviews in medical virology

authors： Moens U,Van Ghelue M,Song X,Ehlers B

更新日期：2013-07-01 00:00:00

abstract：:HIV-1 and HIV-2 share many similarities including their basic gene arrangement, modes of transmission, intracellular replication pathways and clinical consequences: both result in AIDS. However, HIV-2 is characterised by lower transmissibility and reduced likelihood of progression to AIDS. The underlying mechanistic d...

journal_title：Reviews in medical virology

authors： Nyamweya S,Hegedus A,Jaye A,Rowland-Jones S,Flanagan KL,Macallan DC

更新日期：2013-07-01 00:00:00

abstract：:Herpes simplex virus type-1 (HSV-1) is among the most common human pathogens worldwide. Its entry into host cells is an intricate process that relies heavily on the ability of the viral glycoproteins to bind host cellular proteins and to efficiently mediate fusion of the virus envelope with the cell membrane. Acquisit...

journal_title：Reviews in medical virology

authors： Antoine TE,Park PJ,Shukla D

更新日期：2013-05-01 00:00:00

abstract：:Positive-stranded RNA viruses, like many other viruses, have evolved to exploit the host cellular machinery to their own advantage. In eukaryotic cells, the ubiquitin-proteasome system (UPS) that serves as the major intracellular pathway for protein degradation and modification plays a crucial role in the regulation o...

journal_title：Reviews in medical virology

authors： Choi AG,Wong J,Marchant D,Luo H

更新日期：2013-03-01 00:00:00