abstract：INTRODUCTION:Cancer is associated with significant health-care expenditure, but few studies have examined the cost of patients with cancer in the intensive care unit (ICU). We aimed to describe the costs and outcomes of patients admitted to the ICU with cancer. METHODS:We conducted a retrospective cohort study of pati...

journal_title：Journal of intensive care medicine

authors： Zheng B,Reardon PM,Fernando SM,Webber C,Thavorn K,Thompson LH,Tanuseputro P,Munshi L,Kyeremanteng K

更新日期：2021-02-01 00:00:00

abstract：:The rapid spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to a global pandemic. The 2019 coronavirus disease (COVID-19) presents with a spectrum of symptoms ranging from mild to critical illness requiring intensive care unit (ICU) admission. Acute respiratory distress syndrome is a m...

journal_title：Journal of intensive care medicine

authors： Ammar MA,Sacha GL,Welch SC,Bass SN,Kane-Gill SL,Duggal A,Ammar AA

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:To determine whether non-invasive ventilation (NIV) can avoid the need for tracheal intubation and/or reduce the duration of invasive ventilation (IMV) in previously intubated patients admitted to the pediatric intensive care unit (PICU) and developing acute hypoxemic respiratory failure (AHRF) after major tr...

journal_title：Journal of intensive care medicine

authors： Piastra M,De Bellis A,Morena TC,De Luca D,Pezza L,Pizza A,Genovese O,Mancino A,Picconi E,Conti G

更新日期：2021-01-19 00:00:00

abstract：BACKGROUND:Diagnosing acute kidney injury (AKI) stage 3 in critically ill patients may help physicians in making treatment decisions. This diagnosis relies chiefly on urinary output and serum creatinine, which may be of limited value. This study aimed to explore the diagnostic performance of renal resistive index (RRI)...

journal_title：Journal of intensive care medicine

authors： Zhi HJ,Zhao J,Nie S,Ma YJ,Cui XY,Zhang M,Li Y

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:The use of transesophageal echocardiography (TEE) by intensivist physicians (IPs) and emergency physicians (EPs) in critically ill patients is increasing in the intensive care unit, emergency department, and prehospital environments. Coagulopathy and thrombocytopenia are common in critically ill patients. ...

journal_title：Journal of intensive care medicine

authors： Wray TC,Schmid K,Braude D,Azevedo K,Dettmer T,Tawil I,Boivin M,Marinaro J

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:We evaluated the effects of after-hours/nighttime patient transfers out of the ICU on patient outcomes, by performing a systematic review and meta-analysis (PROSPERO CRD 42017074082). DATA SOURCES:MEDLINE, PubMed, EMBASE, Google Scholar, CINAHL, and the Cochrane Library from 1987-November 2019. Conference abst...

journal_title：Journal of intensive care medicine

authors： Moshynskyy AI,Mailman JF,Sy EJ

更新日期：2020-12-28 00:00:00

abstract：OBJECTIVE:When patients deteriorate after decannulation from extracorporeal membrane oxygenation (ECMO), a second run of extracorporeal support may be considered. However, repeat cannulation can be difficult and poor outcomes associated with multiple ECMO runs are a concern. The aim of this study was to evaluate outcom...

journal_title：Journal of intensive care medicine

authors： Cooper DS,Thiagarajan R,Henry BM,Byrnes JW,Misfeldt A,Frischer J,King E,Gao Z,Rycus P,Marino BS

更新日期：2020-12-22 00:00:00

abstract：RATIONALE:The feasibility and clinical outcomes of conservative fluid management after sepsis resuscitation remain unknown. OBJECTIVES:To evaluate the effect of a conservative fluid management protocol on fluid balance and intensive care unit (ICU)-free days among patients with sepsis. METHODS:In a single-center phas...

journal_title：Journal of intensive care medicine

authors： Semler MW,Janz DR,Casey JD,Self WH,Rice TW

更新日期：2020-12-01 00:00:00

abstract：PURPOSE:Conflicting results exist regarding the efficacy of N-acetyl cysteine (NAC) in sepsis treatment. A pivotal factor affecting the therapeutic potency of NAC in sepsis is timing and dosing of its infusion. We aimed to assess the effect of NAC on redox status of patients with sepsis and to compare its efficacy in i...

journal_title：Journal of intensive care medicine

authors： Peivandi Yazdi A,Razavi M,Sheikh S,Boroumand N,Salehi M,Hashemy SI

更新日期：2020-12-01 00:00:00

abstract：:Sepsis is a major cause of morbidity and mortality worldwide. With the advance of medical care, the mortality of sepsis has decreased in the past decades. Many treatments and diagnostic tools still lack supporting evidence. We conducted a retrospective population-based cohort study with propensity score matched subcoh...

journal_title：Journal of intensive care medicine

authors： Chen KF,Tsai MY,Wu CC,Han ST

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Visualization of B-lines via lung ultrasound provides a non-invasive estimation of pulmonary hydration. Extravascular lung water index (EVLWI) and pulmonary vascular permeability index (PVPI) assessed by transpulmonary thermodilution (TPTD) represent the most validated parameters of lung water and alveoloc...

journal_title：Journal of intensive care medicine

authors： Mayr U,Lukas M,Habenicht L,Wiessner J,Heilmaier M,Ulrich J,Rasch S,Schmid RM,Lahmer T,Huber W,Herner A

更新日期：2020-11-05 00:00:00

abstract：PURPOSE:To evaluate the effects of midodrine in addition to intravenous vasopressor therapy on outcomes in adults recovering from shock. MATERIALS AND METHODS:PubMed, Scopus, Clinicaltrials.gov, and published abstracts were searched from inception to November 2018 for studies comparing outcomes in shock after midodrin...

journal_title：Journal of intensive care medicine

authors： Hammond DA,Smith MN,Peksa GD,Trivedi AP,Balk RA,Menich BE

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:To characterize physicians' stated practices in the treatment of patients with severe acute alcohol withdrawal syndrome (sAAWS) and to use intravenous (IV) phenobarbital as an adjuvant treatment for sAAWS. METHODS:A multidisciplinary, cross-sectional, self-administered survey at 2 large academic centers specia...

journal_title：Journal of intensive care medicine

authors： Buell D,Filewod N,Ailon J,Burns KEA

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:The aim of this study was to check if serum lactate was independently associated with mortality among critically ill patients. MATERIALS AND METHODS:This was a single-center, retrospective cohort study. All adult patients (>18 years of age) who had at least 1 measurement of lactate within 24 hours of admission...

journal_title：Journal of intensive care medicine

authors： Chebl RB,Tamim H,Dagher GA,Sadat M,Enezi FA,Arabi YM

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:The management of refractory septic shock remains a major challenge in critical care and its early indicators are not fully understood. We hypothesized that the maximum norepinephrine dosage within 24 hours of intensive care unit (ICU) admission may be a useful indicator of early mortality in patients with s...

journal_title：Journal of intensive care medicine

authors： Kasugai D,Hirakawa A,Ozaki M,Nishida K,Ikeda T,Takahashi K,Matsui S,Uenishi N

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:In the intensive care unit (ICU), prolonged inactivity is common, increasing patients' risk for adverse outcomes, including ICU-acquired weakness. Hence, interventions to minimize inactivity are gaining popularity, highlighting actigraphy, a measure of activity involving a wristwatch-like accelerometer, as a ...

journal_title：Journal of intensive care medicine

authors： Schwab KE,To AQ,Chang J,Ronish B,Needham DM,Martin JL,Kamdar BB

更新日期：2020-11-01 00:00:00

abstract：:Decision-making for the hospitalized dying and critically ill is often characterized by an understanding of autonomy that leads to clinical care and outcomes that are antithetical to patients' preferences around suffering and quality of life. A better understanding of autonomy will facilitate the ultimate goal of a pa...

journal_title：Journal of intensive care medicine

authors： Mapes MV,DePergola PA,McGee WT

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:Timely recognition of critical illness is associated with improved outcomes, but is dependent on accurate triage, which is affected by system factors such as workload and staffing. We sought to first study the effect of delayed recognition on patient outcomes after controlling for system factors and then to ide...

journal_title：Journal of intensive care medicine

authors： Goel NN,Durst MS,Vargas-Torres C,Richardson LD,Mathews KS

更新日期：2020-10-29 00:00:00

abstract：:Acute brain injury (ABI) increases morbidity and mortality in patients with veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Optimal neurologic monitoring methods have not been well-explicated. We studied the use of Near-infrared Spectroscopy (NIRS) to monitor cerebral regional oxygenation tissue saturatio...

journal_title：Journal of intensive care medicine

authors： Hunt MF,Clark KT,Whitman G,Choi CW,Geocadin RG,Cho SM

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:Predicting the mortality from post-operative sepsis remains a continuing problem. We built a statistical model using national data to predict mortality in patients who developed post-operative sepsis. METHODS:This is a retrospective study using the American College of Surgeons National Quality Surgical Impr...

journal_title：Journal of intensive care medicine

authors： Gabriel RA,Trivedi S,Schmidt UH

更新日期：2020-10-12 00:00:00

abstract：INTRODUCTION:A 25-hydroxyvitamin D, 25(OH)D, deficiency is common among critically ill patients and correlated with increased mortality. Furthermore, deficiency is associated with advanced liver disease. However, there are no studies available comparing the dimensions and consequences of a 25(OH)D deficiency between pa...

journal_title：Journal of intensive care medicine

authors： Mayr U,Fahrenkrog-Petersen L,Batres-Baires G,Rasch S,Herner A,Schmid RM,Huber W,Lahmer T

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The efficacy of low-dose hydrocortisone therapy in the management of septic shock remains controversial in critical care for many years. Hence, we performed this meta-analysis of randomized controlled trials (RCTs) with trial sequential analysis (TSA) to evaluate its effect on clinical outcome among adult pa...

journal_title：Journal of intensive care medicine

authors： Lyu QQ,Chen QH,Zheng RQ,Yu JQ,Gu XH

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Agitation is common in the intensive care unit (ICU). Although antipsychotics are frequently used as first-line therapy, chlorpromazine has fallen out of favor due to risk of cardiovascular complications and severe hypotension. Although chlorpromazine is used anecdotally, there is a lack of data regarding it...

journal_title：Journal of intensive care medicine

authors： Choi M,Barra ME,Newman K,Sin JH

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of high-flow nasal cannula oxygen (HFNO) therapy on hospital length of stay (LOS) and postoperative pulmonary complications (PPCs) in adult postoperative patients. DATA SOURCES:PubMed, Embase, the Cochrane Library, Web of Science of Studies, China National Knowledge Index, and Wan Fang...

journal_title：Journal of intensive care medicine

authors： Lu Z,Chang W,Meng S,Xue M,Xie J,Xu J,Qiu H,Yang Y,Guo F

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Circulatory shock affects every third patient in intensive care units and is associated with high mortality. Near-infrared spectroscopy (NIRS) could serve as a means for monitoring tissue perfusion in circulatory shock. PURPOSE:To assess the evidence of NIRS monitoring in circulatory shock, we conducted a s...

journal_title：Journal of intensive care medicine

authors： Varis E,Pettilä V,Wilkman E

更新日期：2020-10-01 00:00:00

abstract：:Intraoperative neuromonitoring was introduced in the second half of the 20th century with the goal of preventing patient morbidity for patients undergoing complex operations of the central and peripheral nervous system. Since its early use for scoliosis surgery, the growth and utilization of IOM techniques expanded dr...

journal_title：Journal of intensive care medicine

authors： Buhl LK,Bastos AB,Pollard RJ,Arle JE,Thomas GP,Song Y,Boone MD

更新日期：2020-09-28 00:00:00

abstract：BACKGROUND:SARS-CoV2 can cause pulmonary failure requiring prolonged invasive mechanical ventilation (MV). Lung protective ventilation strategies are recommended in order to minimize ventilator induced lung injury. Whether patients with COVID-19 have the same risk for complications including barotrauma is still unknown...

journal_title：Journal of intensive care medicine

authors： Udi J,Lang CN,Zotzmann V,Krueger K,Fluegler A,Bamberg F,Bode C,Duerschmied D,Wengenmayer T,Staudacher DL

更新日期：2020-09-22 00:00:00

abstract：BACKGROUND:In the setting of the COVID pandemic, many patients falling ill with acute respiratory distress syndrome eventually require prone positioning for gas exchange. Traditionally, central venous catheters are inserted with patient in the supine or Trendelenburg position. However, when a patient cannot tolerate su...

journal_title：Journal of intensive care medicine

authors： Yang MX,Ng PK

更新日期：2020-09-16 00:00:00

abstract：PURPOSE:Etomidate causes adrenal insufficiency. Yet in critically ill patients, it is controversial whether it increases mortality rates above that of comparator anesthetic induction agents. We postulated that etomidate would increase relative mortality rates correspondingly to the severity of illness as defined by SAP...

journal_title：Journal of intensive care medicine

authors： Albert SG,Sitaula S

更新日期：2020-09-10 00:00:00

abstract：OBJECTIVE:To examine racial and ethnic differences in the utilization of 3 interventions (tracheostomy placement, gastrostomy tube placement, and hospice utilization) among patients with severe acute brain injury (SABI). DESIGN:Retrospective cohort study. SETTING:Data from the National Inpatient Sample, from 2002 to ...

journal_title：Journal of intensive care medicine

authors： Jones RC,Creutzfeldt CJ,Cox CE,Haines KL,Hough CL,Vavilala MS,Williamson T,Hernandez A,Raghunathan K,Bartz R,Fuller M,Krishnamoorthy V

更新日期：2020-09-10 00:00:00

abstract：BACKGROUND:There is variation in the treatment of patients with severe alcohol withdrawal and a need for effective protocols. The purpose of this study was to evaluate the implementation of a symptom-triggered benzodiazepine protocol using the 5-item Brief Alcohol Withdrawal Scale (BAWS) for treatment of alcohol withdr...

journal_title：Journal of intensive care medicine

authors： Rastegar DA,Jarrell AS,Chen ES

更新日期：2020-08-27 00:00:00

abstract：BACKGROUND:Sepsis coagulopathy or disseminated intravascular coagulation (DIC) mainly due to progressive endothelial disruption and damage. The glycocalyx is expressed on the endothelial cell surface and contributes to anti-thrombogenicity, anti-inflammatory, and regulates vascular permeability. We aimed to evaluate th...

journal_title：Journal of intensive care medicine

authors： Huang X,Hu H,Sun T,Zhu W,Tian H,Hao D,Wang T,Wang X

更新日期：2020-08-17 00:00:00

abstract：:The whole-brain criterion of death provides that a person who has irreversibly lost all clinical functions of the brain is dead. Bedside brain death (BD) tests permit physicians to determine BD by showing that the whole-brain criterion of death has been fulfilled. In a nonsystematic literature review, we identified an...

journal_title：Journal of intensive care medicine

authors： Dalle Ave AL,Bernat JL

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Pharmacogenomic (PGx) testing has the potential to provide information on specific drug-metabolizing enzymes that may lead to an absence, reduction, or increase in medication effect in patients. There is a paucity of prospective studies examining PGx testing in the intensive care unit (ICU) setting. RESEARC...

journal_title：Journal of intensive care medicine

authors： Peterson PE,Nicholson WT,Moyer AM,Arendt CJ,Smischney NJ,Seelhammer TG,Krecke CA,Haney RM,Yaw EJ,Chlan LL

更新日期：2020-07-31 00:00:00

abstract：BACKGROUND:Ischemic and hypoxic secondary brain insults are common and detrimental in traumatic brain injury (TBI). Treatment aims to maintain an adequate cerebral blood flow with sufficient arterial oxygen content. It has been suggested that arterial hyperoxia may be beneficial to the injured brain to compensate for c...

journal_title：Journal of intensive care medicine

authors： Wettervik TS,Engquist H,Howells T,Lenell S,Rostami E,Hillered L,Enblad P,Lewén A

更新日期：2020-07-27 00:00:00

abstract：BACKGROUND:At this time, there are no studies evaluating the risk of delirium or coma with the use of ketamine in mechanically ventilated adult patients, compared to conventional therapies such as propofol or dexmedetomidine. OBJECTIVE:The objective of this study was to evaluate the number of days alive without deliri...

journal_title：Journal of intensive care medicine

authors： Shurtleff V,Radosevich JJ,Patanwala AE

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:Percutaneous dilational tracheostomy (PDT) is a common and increasingly used procedure in the intensive care unit (ICU). It is usually performed with bronchoscopy guidance. Ultrasound has emerged as a useful tool in order to assist PDT, potentially improving its success rate and reducing procedural-related...

journal_title：Journal of intensive care medicine

authors： Gobatto ALN,Besen BAMP,Cestari M,Pelosi P,Malbouisson LMS

更新日期：2020-05-01 00:00:00

abstract：:Patients admitted to the cardiac intensive care unit (CICU) are often in shock and require hemodynamic support. Identifying and addressing the pathophysiology mechanisms operating in an individual patient is crucial to achieving a successful outcome, while initiating circulatory support therapy to restore adequate tis...

journal_title：Journal of intensive care medicine

authors： Jentzer JC,Hollenberg SM

更新日期：2020-04-13 00:00:00

abstract：OBJECTIVE:Fluid responsiveness is the ability to increase the cardiac output in response to a fluid challenge. Only about 50% of patients receiving fluid resuscitation for acute circulatory failure increase their stroke volume, but the other 50% may worsen their outcome. Therefore, predicting fluid responsiveness is ne...

journal_title：Journal of intensive care medicine

authors： Orso D,Paoli I,Piani T,Cilenti FL,Cristiani L,Guglielmo N

更新日期：2020-04-01 00:00:00

abstract：:Objectives: Standard management strategies for lowering intracranial pressure (ICP) in traumatic brain injury has been well-studied, but the use of lesser known interventions for ICP in subarachnoid hemorrhage (SAH) remains elusive. Searches were performed in PubMed and EBSCO Host to identify best available evidence f...

journal_title：Journal of intensive care medicine

authors： Ravishankar N,Nuoman R,Amuluru K,El-Ghanem M,Thulasi V,Dangayach NS,Lee K,Al-Mufti F

更新日期：2020-03-01 00:00:00