Abstract:
OBJECTIVE:To evaluate the effect of high-flow nasal cannula oxygen (HFNO) therapy on hospital length of stay (LOS) and postoperative pulmonary complications (PPCs) in adult postoperative patients. DATA SOURCES:PubMed, Embase, the Cochrane Library, Web of Science of Studies, China National Knowledge Index, and Wan Fang databases were searched until July 2018. STUDY SELECTION:Randomized controlled trials (RCTs) comparing HFNO with conventional oxygen therapy or noninvasive mechanical ventilation in adult postoperative patients were included. The primary outcomes were hospital LOS and PPCs; short-term mortality (defined as intensive care unit, hospital, or 28-day mortality) and intubation rate were the secondary outcomes. DATA EXTRACTION:Demographic variables, high-flow oxygen therapy application, effects, and side effects were retrieved. Data were analyzed by the methods recommended by the Cochrane Collaboration. The strength of evidence was assessed by the Grading of Recommendations Assessment, Development and Evaluation. Random errors were evaluated with trial sequential analysis. DATA SYNTHESIS:Fourteen studies (2568 patients) met the inclusion criteria and were included. Compared to the control group, the pooled effect showed that HFNO was significantly associated with a shorter hospital stay (mean difference: -0.81; 95% confidence interval [CI]: -1.34 to -0.29, P = .002), but not mortality (risk ratio [RR]: 1.0, 95% CI: 0.63 to 1.59, P = 1.0). Weak evidence of a reduction in reintubation rate (RR: 0.76, 95% CI: 0.57-1.01, P = .06) and PPC rate (RR: 0.89, 95% CI: 0.75-1.06, P = .18) with HFNO versus control group was recorded. CONCLUSIONS:The available RCTs suggest that, among the adult postoperative patients, HFNO therapy compared to the control group significantly reduces hospital LOS.
journal_name
J Intensive Care Medjournal_title
Journal of intensive care medicineauthors
Lu Z,Chang W,Meng S,Xue M,Xie J,Xu J,Qiu H,Yang Y,Guo Fdoi
10.1177/0885066618817718subject
Has Abstractpub_date
2020-10-01 00:00:00pages
1129-1140issue
10eissn
0885-0666issn
1525-1489journal_volume
35pub_type
杂志文章abstract::Venous thromboembolism (VTE) is a major health concern associated with significant morbidity and mortality. Critically ill patients are at an increased risk of VTE compared to general medical patients due to unique risk factors: prolonged immobilization, invasive lines and devices, certain medications, and acquired th...
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更新日期:2019-11-01 00:00:00
abstract:RATIONALE:The feasibility and clinical outcomes of conservative fluid management after sepsis resuscitation remain unknown. OBJECTIVES:To evaluate the effect of a conservative fluid management protocol on fluid balance and intensive care unit (ICU)-free days among patients with sepsis. METHODS:In a single-center phas...
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abstract:BACKGROUND:Admission to an intensive care unit (ICU) specialized for brain and spine injury patients is associated with improved outcome. We investigated the effects of the first dedicated, combined neurological and neurosurgical ICU (NeuroICU) in Korea on patient outcomes. METHODS:The first dedicated NeuroICU in Kore...
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更新日期:2015-07-01 00:00:00
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更新日期:1995-03-01 00:00:00
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更新日期:2020-08-01 00:00:00
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journal_title:Journal of intensive care medicine
pub_type: 杂志文章,多中心研究
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更新日期:2014-03-01 00:00:00
abstract::Antibacterial resistance is increasing throughout the world, while the development of new agents is slowly progressing. In addition, the increasing prevalence of fluoroquinolone resistance may force many practitioners to choose an aminoglycoside agent in gram-negative regimens. Aminoglycosides are bactericidal agents ...
journal_title:Journal of intensive care medicine
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更新日期:2010-11-01 00:00:00
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更新日期:2006-05-01 00:00:00
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journal_title:Journal of intensive care medicine
pub_type: 杂志文章,评审
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更新日期:1991-03-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2018-09-01 00:00:00
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更新日期:2014-01-01 00:00:00
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更新日期:2017-05-01 00:00:00
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更新日期:2008-07-01 00:00:00
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更新日期:2020-09-10 00:00:00
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更新日期:2020-07-27 00:00:00
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journal_title:Journal of intensive care medicine
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更新日期:2013-01-01 00:00:00
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更新日期:2019-11-05 00:00:00
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更新日期:2014-11-01 00:00:00
abstract::In the last 10 years, lung transplantation has become an increasingly common procedure for patients with end-stage respiratory disease. Although long-term survival can be achieved, there is still significant morbidity within the first year. Early postoperative problems that may be anticipated include respiratory insu...
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更新日期:1991-05-01 00:00:00