abstract：BACKGROUND & AIMS:Fontan surgery for single ventricle congenital heart disease leads to Fontan-associated liver disease (FALD). Typical laboratory tests, imaging, and histopathology cannot predict clinical severity in FALD. HepQuant SHUNT is a proprietary serum test of hepatic function and physiology that has not yet b...

journal_title：Congenital heart disease

authors： Lemmer A,VanWagner L,Gasanova Z,Helmke S,Everson GT,Ganger D

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Traveling to high altitude has become more popular. High-altitude exposure causes hypobaric hypoxia. Exposure to acute high altitude, during air travel or mountain stays, seems to be safe for most patients with congenital heart disorders (CHD). Still, current guidelines for CHD patients express concerns rega...

journal_title：Congenital heart disease

authors： Takken T,Evertse A,de Waard F,Spoorenburg M,Kuijpers M,Schroer C,Hulzebos EH

更新日期：2019-11-01 00:00:00

abstract：INTRODUCTION:Surveillance and management guidelines for Fontan patients are lacking due to the paucity of evidence in the literature of screening efficacy on outcome measures. METHODS:The Fontan Working Group within the New England Congenital Cardiology Association designed an electronic survey to assess surveillance ...

journal_title：Congenital heart disease

authors： Davey BT,Toro-Salazar OH,Gauthier N,Valente AM,Elder RW,Wu FM,Berman N,Pollack P,Lee JH,Rathod RH

更新日期：2019-11-01 00:00:00

abstract：INTRODUCTION:Health care-associated infections (HAIs) increase mortality, length of stay, and cost in hospitalized patients. The incidence of and risk factors for developing HAIs in the pediatric population after cardiac surgery have been studied. This study evaluates the impact of HAIs on length of stay, inpatient mor...

journal_title：Congenital heart disease

authors： Tweddell S,Loomba RS,Cooper DS,Benscoter AL

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:Cardiovascular lesions are the leading cause of morbidity and mortality in patients with Williams syndrome. Recent studies have rebutted conventional reports about the natural course of cardiovascular anomalies in Williams syndrome. DESIGN:Retrospective study. SETTING:Single tertiary center. PATIENTS:Eight...

journal_title：Congenital heart disease

authors： Cha SG,Song MK,Lee SY,Kim GB,Kwak JG,Kim WH,Bae EJ

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:Patients undergoing surgical repair of aortic coarctation have a 50% risk of pathologic left ventricular remodeling (increased left ventricular mass or relative wall thickness). Endothelin 1, ST2, galectin 3, norepinephrine and B-natriuretic peptide are biomarkers that have been associated with pathologic LV ...

journal_title：Congenital heart disease

authors： Frank BS,Urban TT,Lewis K,Tong S,Cassidy C,Mitchell MB,Nichols CS,Davidson JA

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Patients with a Fontan circulation are at risk of renal dysfunction. We analyzed cross-sectional data in pediatric and adult Fontan patients in order to assess the accuracy of commonly used serum creatinine-based methods in estimating glomerular filtration rate (GFR). METHODS:A total of 124 Fontan patients ...

journal_title：Congenital heart disease

authors： Wilson TG,d'Udekem Y,Winlaw DS,Cordina RL,Ayer J,Gentles TL,Weintraub RG,Grigg LE,Cheung M,Cain TM,Rao P,Verrall C,Plessis KD,Rice K,Iyengar AJ

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:Management of the patients with transposition of the great arteries and intact ventricular septum may be challenging beyond the newborn period. Herein, we would like to present our alternative strategy for training the left ventricle in these patients. METHODS:Six patients with transposition of the great art...

journal_title：Congenital heart disease

authors： Bilal MS,Özyüksel A,Kemal Avşar M,Demiroluk Ş,Küçükosmanoğlu O,Yalçın Y

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Physician burnout has many undesirable consequences, including negative impact on patient care delivery and physician career satisfaction. Electronic health records (EHRs) may exacerbate burnout by increasing physician workload. OBJECTIVE:To determine burnout in adult congenital heart disease (ACHD) special...

journal_title：Congenital heart disease

authors： Marckini DN,Samuel BP,Parker JL,Cook SC

更新日期：2019-05-01 00:00:00

abstract：AIM:The Fontan circulation is highly dependent on ventilation, improving pulmonary blood flow and cardiac output. A reduced ventilatory function is reported in these patients. The extent of this impairment and its relation to exercise capacity and quality of life is unknown and objective of this study. METHODS:This mu...

journal_title：Congenital heart disease

authors： Callegari A,Neidenbach R,Milanesi O,Castaldi B,Christmann M,Ono M,Müller J,Ewert P,Hager A

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:The current study aims to identify the rates of lapses in care and loss to follow-up before age one through age five for white and nonwhite congenital heart disease (CHD) survivors. Nonwhite CHD survivors were hypothesized to experience an earlier lapse in care and be lost to follow-up than whites. DESIGN:Pa...

journal_title：Congenital heart disease

authors： Jackson JL,Morack J,Harris M,DeSalvo J,Daniels CJ,Chisolm DJ

更新日期：2019-03-01 00:00:00

abstract：:Clinically significant patent ductus arteriosus (PDA) has been associated with significant morbidity in extremely low birth weight (ELBW) infants. Current management of ELBW infants with hemodynamically significant PDA includes supportive treatment, pharmacological therapy, and surgical ligation. All of these therapeu...

journal_title：Congenital heart disease

authors： Almeida-Jones M,Tang NY,Reddy A,Zahn E

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:We aimed to study the efficiency and safety of once-a-week outpatient rehabilitation followed by home program with tele-monitoring in patients with complex cyanotic congenital heart disease. DESIGN:Prospective nonrandomized study. METHOD:Patients who have been diagnosed either Eisenmenger's syndrome or inop...

journal_title：Congenital heart disease

authors： Bhasipol A,Sanjaroensuttikul N,Pornsuriyasak P,Yamwong S,Tangcharoen T

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:Amiodarone is a highly effective antiarrhythmic therapy, however its toxicity profile often limits treatment. This is particularly relevant in adults with congenital heart disease (CHD), who are often young and in whom other antiarrhythmic agents commonly fail or are contraindicated. We sought to determine in...

journal_title：Congenital heart disease

authors： Moore BM,Cordina RL,McGuire MA,Celermajer DS

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Congenital heart defects affect nearly 1% of all children born per year in the United States, and complete atrioventricular canal (CAVC) accounts for 2%-9%. While several patch materials have been used for septal defect closure during CAVC repair, clear superiority of one material over another has yet to be ...

journal_title：Congenital heart disease

authors： Al Haddad E,LaPar DJ,Dayton J,Stephens EH,Bacha E

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:The aim is to present current clinical practice of thoracic aorta screening in a tertiary referral center. We identified how often imaging techniques were used for screening and established the value of transthoracic echocardiography (TTE) in comparison with computed tomography (CT) to detect aortic dilation....

journal_title：Congenital heart disease

authors： Bons LR,Uchoa de Assis L,Dekker S,Kauling RM,Cuypers JAAE,Verhagen HJM,Budde RPJ,Roos-Hesselink JW

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:The 2016 American Board of Pediatrics (ABP) content outline is comprehensive, including more than 50 cardiology-specific objectives within eight content areas. This study complements the quantitative analysis of a Kentucky-wide survey of trainees, pediatricians, and pediatric cardiologists asking them to iden...

journal_title：Congenital heart disease

authors： Neal AE,Lehto E,Miller KH,Davis E,Ziegler C

更新日期：2018-09-01 00:00:00

abstract：INTRODUCTION:Ketamine is a drug often used for procedural sedation or as adjunct agent for general sedation in children with congenital heart disease. In the clinical realm, there is often confusion regarding the effects of ketamine on hemodynamics, particularly pulmonary vascular resistance and systemic vascular resis...

journal_title：Congenital heart disease

authors： Loomba RS,Gray SB,Flores S

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Mean platelet volume (MPV), platecrit, and platelet distribution width (PDW) are markers of platelet activation. Previous studies have found that platelet activation occurs in patients with pulmonary arterial hypertension. Platelet indices including MPV, PDW, and platecrit have not been studied in children w...

journal_title：Congenital heart disease

authors： Mese T,Guven B,Yilmazer MM,Karadeniz C,Ozdemir R,Doksoz O

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:Inappropriate implantable cardioverter defibrillator (ICD) shocks in children and patients with congenital heart disease (CHD) remain a major complication of device therapy, occurring in as many as 50% of children with ICDs. New generation devices include algorithms designed to minimize inappropriate shocks. ...

journal_title：Congenital heart disease

authors： Goldstein SA,LaPage MJ,Dechert BE,Serwer GA,Yu S,Lowery RE,Bradley DJ

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:We previously identified a pathogenic germline DICER1 variant in a child with transposition of the great arteries who was a member of a family with DICER1 syndrome. In view of a report linking Dicer1 knockout in murine cardiomyocytes to cardiac outflow defects, we investigated the involvement of DICER1 in tra...

journal_title：Congenital heart disease

authors： Sabbaghian N,Digilio MC,Blue GM,Revil T,Winlaw DS,Foulkes WD

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:It is unclear whether neonates with interrupted aortic arch (IAA) and a smaller left ventricular outflow tract may have improved outcomes with a Yasui operation (ventricular outflow bypass procedure) over a primary complete repair. This study sought to identify preoperative echocardiographic parameters to dif...

journal_title：Congenital heart disease

authors： Abarbanell G,Border WL,Schlosser B,Morrow G,Kelleman M,Sachdeva R

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Children and adolescents with congenital heart disease (CHD) and their families require qualified combined medical and psychosocial information, care, and counseling. This study aimed to analyze CHD patients' and parents' perception of disease-specific knowledge, state of health, and impairments experienced ...

journal_title：Congenital heart disease

authors： Helm PC,Kempert S,Körten MA,Lesch W,Specht K,Bauer UMM

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of using fetal heart size measurements derived from axial echocardiography to predict homozygous α-thalassemia-1. DESIGN:Prospective diagnostic study. SETTING:The carrier rate of α-thalassemia-1 (-/αα) in China's Guangxi Zhuang Autonomous Region is approximately 15%. If both parents...

journal_title：Congenital heart disease

authors： Li X,Qiu X,Huang H,Zhao Y,Li X,Li M,Tian X

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Pulmonary atresia with intact ventricular septum is a unique congenital malformation of the heart in which patients may undergo single-, two- or 1½- ventricle repair. Size of the tricuspid valve annulus, morphology of the right ventricle and presence of ventriculocoronary connections can all impact the selec...

journal_title：Congenital heart disease

authors： Loomba RS,Pelech AN

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Cardiovascular diseases in pediatric pathologies have emerged in the recent years in sub-Saharan Africa (SSA), with congenital heart diseases (CHDs) being the most frequent. Unfortunately, their diagnosis is usually delayed, thereby increasing childhood morbidity and mortality. OBJECTIVES:Describe the cli...

journal_title：Congenital heart disease

authors： Kamdem F,Kedy Koum D,Hamadou B,Yemdji M,Luma H,Doualla MS,Noukeu D,Barla E,Akazong C,Dzudie A,Ngote H,Monkam Y,Mouliom S,Kingue S

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:The study examined parent stress and health-related quality of life (HRQOL) among families of children with congenital heart disease (CHD) referred for psychological services. METHODS:Parents of 54 children (85% boys) aged 3 to 13 (Mage  = 7.48, SD = 2.38) completed measures to assess parenting stress (Paren...

journal_title：Congenital heart disease

authors： Kaugars A,Shields C,Brosig C

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:This study aims to assess and compare the early and long-term effects of extracardiac conduit (EC) and lateral tunnel (LT) in patients with a functional single ventricle through meta-analysis. DESIGN:A systematic search was performed in PubMed, Embase, Cochrane Library, CNKI, VIP, CBM, and WanFang databases ...

journal_title：Congenital heart disease

authors： Lin Z,Ge H,Xue J,Wu G,Du J,Hu X,Zhao Q

更新日期：2017-12-01 00:00:00

abstract：:A genetic basis of congenital heart disease (CHD) has been known for decades. In addition to the sequence of the genome, the contribution of epigenetics to pediatric cardiology is increasingly recognized. Multiple epigenetic mechanisms, including DNA methylation, histone modification, and RNA-based regulation, are kno...

journal_title：Congenital heart disease

authors： Spearman AD

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:To investigate survival and freedom from reintervention after aortic coarctation repair in Maltese patients and to compare cardiovascular mortality in coarctation repair survivors with that in the general population. DESIGN:All 72 aortic coarctation patients with any type of repair, born by end-1997 and log...

journal_title：Congenital heart disease

authors： Caruana M,Grech V

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:We hypothesized that a right aortic arch in situs solitus, with or without an associated cardiovascular malformation, is often associated with a vascular ring. METHODS:From those born in Southern Nevada between March 2012 and March 2017, we identified 50 (3.6 per 10,000 live births) with a right aortic arch ...

journal_title：Congenital heart disease

authors： Evans WN,Acherman RJ,Ciccolo ML,Carrillo SA,Mayman GA,Luna CF,Rollins RC,Castillo WJ,Galindo A,Rothman A,Alexander JA,Kwan TW,Restrepo H

更新日期：2017-09-01 00:00:00

abstract：:Currently, the role of stress echocardiography primarily resides in diagnosing acquired coronary artery disease (CAD) in adults. Besides an increasing concern for traditional CAD in young patients due to obesity and other chronic pediatric diseases, there is also a growing population of adolescents and young adults wi...

journal_title：Congenital heart disease

authors： Ermis P

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:Atypical development, behavioral difficulties, and academic underachievement are common morbidities in children with a history of congenital heart defects and impact quality of life. Language and social-cognitive deficits have been described, which are associated with autism spectrum disorders. The current st...

journal_title：Congenital heart disease

authors： Bean Jaworski JL,Flynn T,Burnham N,Chittams JL,Sammarco T,Gerdes M,Bernbaum JC,Clancy RR,Solot CB,Zackai EH,McDonald-McGinn DM,Gaynor JW

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:We aimed (1) determine if systemic right ventricle filling parameters influence systemic right ventricle stroke volume in adult patients with D-transposition of the great arteries (D-TGA) palliated by atrial switch, using cardiac magnetic resonance imaging and echocardiography, and (2) to study relationship ...

journal_title：Congenital heart disease

authors： Ladouceur M,Kachenoura N,Soulat G,Bollache E,Redheuil A,Azizi M,Delclaux C,Chatellier G,Boutouyrie P,Iserin L,Bonnet D,Mousseaux E

更新日期：2017-07-01 00:00:00

abstract：INTRODUCTION:With increasing survival of children with HLHS and other single ventricle lesions, the complexity of medical care for these patients is substantial. Establishing and adhering to best practice models may improve outcome, but requires careful coordination and monitoring. METHODS:In 2013 our Heart Center beg...

journal_title：Congenital heart disease

authors： Texter K,Davis JAM,Phelps C,Cheatham S,Cheatham J,Galantowicz M,Feltes TF

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:Enteral feeding is associated with decreased infection rates, decreased mechanical ventilation, decreased hospital length of stay, and improved wound healing. Enteral feeding difficulties are common in congenital heart disease. Our objective was to develop experience-based newborn feeding guidelines for the i...

journal_title：Congenital heart disease

authors： Simsic JM,Carpenito KR,Kirchner K,Peters S,Miller-Tate H,Joy B,Galantowicz M

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:The National Pediatric Cardiology Quality Improvement Collaborative (NPC-QIC) was established in 2008 to improve outcomes of hypoplastic left heart syndrome (HLHS) during the interstage period. They evaluated changes in patient variables and practice variation between early and late eras. DESIGN:Data includi...

journal_title：Congenital heart disease

authors： Carlo WF,Cnota JF,Dabal RJ,Anderson JB

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:The aims of this study were to compare the level of posttraumatic stress disorder between adults with and without congenital heart disease, and to examine the correlates of posttraumatic stress disorder (e.g., sociodemographics). DESIGN:Cross-sectional. SETTING:Two university-affiliated heart hospitals in T...

journal_title：Congenital heart disease

authors： Eslami B

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Deficits in swallowing physiology are a leading morbidity for infants with functional single ventricles and systemic outflow tract obstruction following stage 1 palliation. Despite the high prevalence of this condition, the underlying deficits that cause this post-operative impairment remain poorly understoo...

journal_title：Congenital heart disease

authors： McGrattan KE,McGhee H,DeToma A,Hill EG,Zyblewski SC,Lefton-Greif M,Halstead L,Bradley SM,Martin-Harris B

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:The primary objective of this study was to demonstrate that pulmonary artery (PA) debanding via cardiac catheterization using balloon angioplasty is feasible and safe in swine. The secondary objectives were to determine the acute and long-term effects of this therapy. DESIGN:This is a chronic survival exper...

journal_title：Congenital heart disease

authors： Perez M,Kumar TS,Hoskoppal D,Akkhawattanangkul Y,Allen K,Knott-Craig CJ,Waller BR,Sathanandam S

更新日期：2017-05-01 00:00:00