abstract：:Zika virus (ZIKV) is a mosquito-borne virus of the flavivirus genus in the Flaviviridae family. Flaviviruses are single-stranded, positive-sense RNA viruses that have been responsible for numerous human epidemics. Notable flaviviruses include mosquito-borne viruses such as yellow fever virus (YFV), Dengue virus (DENV)...

journal_title：Advances in virus research

authors： Platt DJ,Miner JJ

更新日期：2020-01-01 00:00:00

abstract：:Coronaviruses (CoVs) have caused outbreaks of deadly pneumonia in humans since the beginning of the 21st century. The severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in 2002 and was responsible for an epidemic that spread to five continents with a fatality rate of 10% before being contained in 2003 (w...

journal_title：Advances in virus research

authors： Tortorici MA,Veesler D

更新日期：2019-01-01 00:00:00

abstract：:Membrane fusion is a fundamental biological process that allows different cellular compartments delimited by a lipid membrane to release or exchange their respective contents. Similarly, enveloped viruses such as alphaherpesviruses exploit membrane fusion to enter and infect their host cells. For infectious entry the ...

journal_title：Advances in virus research

authors： Vallbracht M,Backovic M,Klupp BG,Rey FA,Mettenleiter TC

更新日期：2019-01-01 00:00:00

abstract：:Plant viruses possess adaptations for facilitating acquisition, retention, and inoculation by vectors. Until recently, it was hypothesized that these adaptations are limited to virus proteins that enable virions to bind to vector mouthparts or invade their internal tissues. However, increasing evidence suggests that v...

journal_title：Advances in virus research

authors： Mauck KE,Chesnais Q,Shapiro LR

更新日期：2018-01-01 00:00:00

abstract：:Waterbirds are the main reservoir for low pathogenic avian influenza A viruses (LPAIV), from which occasional spillover to poultry occurs. When circulating among poultry, LPAIV may become highly pathogenic avian influenza A viruses (HPAIV). In recent years, the epidemiology of HPAIV viruses has changed drastically. HP...

journal_title：Advances in virus research

authors： Bodewes R,Kuiken T

更新日期：2018-01-01 00:00:00

abstract：:Rodents are distributed throughout the world and interact with humans in many ways. They provide vital ecosystem services, some species are useful models in biomedical research and some are held as pet animals. However, many rodent species can have adverse effects such as damage to crops and stored produce, and they a...

journal_title：Advances in virus research

authors： Drewes S,Straková P,Drexler JF,Jacob J,Ulrich RG

更新日期：2017-01-01 00:00:00

abstract：:The risk of spillover of enzootic paramyxoviruses and the susceptibility of recipient human and domestic animal populations are defined by a broad collection of ecological and molecular factors that interact in ways that are not yet fully understood. Nipah and Hendra viruses were the first highly lethal zoonotic param...

journal_title：Advances in virus research

authors： Thibault PA,Watkinson RE,Moreira-Soto A,Drexler JF,Lee B

更新日期：2017-01-01 00:00:00

abstract：:Nepoviruses supplied seminal landmarks to the historical trail of plant virology. Among the first agriculturally relevant viruses recognized in the late 1920s and among the first plant viruses officially classified in the early 1970s, nepoviruses also comprise the first species for which a soil-borne ectoparasitic nem...

journal_title：Advances in virus research

authors： Fuchs M,Schmitt-Keichinger C,Sanfaçon H

更新日期：2017-01-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) gives rise to a chronic infection that progressively depletes CD4(+) T lymphocytes. CD4(+) T lymphocytes play a central coordinating role in adaptive cellular and humoral immune responses, and to do so they migrate and interact within lymphoid compartments and at effector si...

journal_title：Advances in virus research

authors： Law KM,Satija N,Esposito AM,Chen BK

更新日期：2016-01-01 00:00:00

abstract：:Alphaherpesviruses infect a variety of species from sea turtles to man and can cause significant disease in mammals including humans and livestock. These viruses are characterized by a lytic and latent state in nerve ganglia, with the ability to establish a lifelong latent infection that is interrupted by periodic rea...

journal_title：Advances in virus research

authors： Bloom DC

更新日期：2016-01-01 00:00:00

abstract：:Grapevine is a high value vegetatively propagated fruit crop that suffers from numerous viruses, including some that seriously affect the profitability of vineyards. Nowadays, 64 viruses belonging to different genera and families have been reported in grapevines and new virus species will likely be described in the fu...

journal_title：Advances in virus research

authors： Maliogka VI,Martelli GP,Fuchs M,Katis NI

更新日期：2015-01-01 00:00:00

abstract：:The incurable nature of viral diseases and the public awareness to the harmful effects of chemical pest control to the environment and human health led to the rise of the integrated pest management (IPM) concept. Cultural control methods serve today as a central pivot in the implementation of IPM. This group of method...

journal_title：Advances in virus research

authors： Antignus Y

更新日期：2014-01-01 00:00:00

abstract：:Dengue virus (DENV) is an emerging mosquito-borne human pathogen that affects millions of individuals each year by causing severe and potentially fatal syndromes. Despite intense research efforts, no approved vaccine or antiviral therapy is yet available. Overcoming this limitation requires detailed understanding of t...

journal_title：Advances in virus research

authors： Acosta EG,Kumar A,Bartenschlager R

更新日期：2014-01-01 00:00:00

abstract：:The genus Dianthovirus is one of eight genera in the family Tombusviridae. All the genera have monopartite positive-stranded RNA genomes, except the dianthoviruses which have bipartite genomes. The dianthoviruses are distributed worldwide. Although they share common structural features with the other Tombusviridae vir...

journal_title：Advances in virus research

authors： Okuno T,Hiruki C

更新日期：2013-01-01 00:00:00

abstract：:Most of the major fungal families including plant-pathogenic fungi, yeasts, and mushrooms are infected by mycoviruses, and many double-stranded RNA (dsRNA) mycoviruses have been recently identified from diverse plant-pathogenic Fusarium species. The frequency of occurrence of dsRNAs is high in Fusarium poae but low in...

journal_title：Advances in virus research

authors： Cho WK,Lee KM,Yu J,Son M,Kim KH

更新日期：2013-01-01 00:00:00

abstract：:The regular increase of drug-resistant pathogens has been a major force in the renewed interest in the use of bacteriophages as therapeutics. In addition to experience acquired in eastern Europe where bacteriophages have been used to treat bacterial infections in humans, in Western countries only experimental models h...

journal_title：Advances in virus research

authors： Saussereau E,Debarbieux L

更新日期：2012-01-01 00:00:00

abstract：:Lettuce is frequently attacked by several viruses causing disease epidemics and considerable yield losses along the Mediterranean basin. Aphids are key pests and the major vectors of plant viruses in lettuce fields. Lettuce mosaic virus (LMV) is probably the most important because it is seed-transmitted in addition to...

journal_title：Advances in virus research

authors： Moreno A,Fereres A

更新日期：2012-01-01 00:00:00

abstract：:Ever since their discovery, archaeal viruses have fascinated biologists with their unusual virion morphotypes and their ability to thrive in extreme environments. Attempts to understand the biology of these viruses through genome sequence analysis were not efficient. Genomes of archaeoviruses proved to be terra incogn...

journal_title：Advances in virus research

authors： Krupovic M,White MF,Forterre P,Prangishvili D

更新日期：2012-01-01 00:00:00

abstract：:Coronaviruses infect many species of animals including humans, causing acute and chronic diseases. This review focuses primarily on the pathogenesis of murine coronavirus mouse hepatitis virus (MHV) and severe acute respiratory coronavirus (SARS-CoV). MHV is a collection of strains, which provide models systems for th...

journal_title：Advances in virus research

authors： Weiss SR,Leibowitz JL

更新日期：2011-01-01 00:00:00

abstract：:In contrast to viruses of plants and animals, viruses of fungi, mycoviruses, uniformly lack an extracellular phase to their replication cycle. The persistent, intracellular nature of the mycovirus life cycle presents technical challenges to experimental design. However, these properties, coupled with the relative simp...

journal_title：Advances in virus research

authors： Nuss DL

更新日期：2011-01-01 00:00:00

abstract：:Numerous bat species have been identified as important reservoirs of zoonotic viral pathogens. Rabies and rabies-related viruses constitute one of the most important viral zoonoses and pose a significant threat to public health across the globe. Whereas rabies virus (RABV) appears to be restricted to bats of the New W...

journal_title：Advances in virus research

authors： Banyard AC,Hayman D,Johnson N,McElhinney L,Fooks AR

更新日期：2011-01-01 00:00:00

abstract：:Rabies virus (RABV) and other negative-strand RNA viruses are the causes of serious diseases in humans and animals worldwide. Assembly and budding are important late events in the replication cycles of these negative-strand RNA viruses that have received much attention in the past decade. Indeed, important insights in...

journal_title：Advances in virus research

authors： Okumura A,Harty RN

更新日期：2011-01-01 00:00:00

abstract：:The Gammaherpesvirinae subfamily of herpesviruses comprises lymphotropic viruses, including the oncogenic human pathogens Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus. During lytic infection, gammaherpesviruses manipulate host gene expression to optimize the cellular environment for viral replication...

journal_title：Advances in virus research

authors： Clyde K,Glaunsinger BA

更新日期：2010-01-01 00:00:00

abstract：:Virus infection may damage the plant, and plant defenses are effective against viruses; thus, it is currently assumed that plants and viruses coevolve. However, and despite huge advances in understanding the mechanisms of pathogenicity and virulence in viruses and the mechanisms of virus resistance in plants, evidence...

journal_title：Advances in virus research

authors： Fraile A,García-Arenal F

更新日期：2010-01-01 00:00:00

abstract：:Outbreaks of influenza A viruses continue to cause morbidity and mortality worldwide. The global disease burden of influenza is substantial. While antiviral therapies are available, influenza vaccines are the mainstay of efforts to reduce the substantial health burden from seasonal influenza. Inactivated influenza vac...

journal_title：Advances in virus research

authors： Schultz-Cherry S,Jones JC

更新日期：2010-01-01 00:00:00

abstract：:In 1959, 5-iodo-2'-deoxyuridine (IDU) was described, the first antiviral drug ever to be (and still) marketed (for the topical treatment of herpetic keratitis). Now 50 years following the description (of the synthesis) of IDU, we have 50 compounds on the market that have been licensed for clinical use in the treatment...

journal_title：Advances in virus research

authors： De Clercq E

更新日期：2009-01-01 00:00:00

abstract：:Influenza is a zoonotic viral disease that represents a health and economic threat to both humans and animals worldwide. Swine influenza (SI) was first recognized clinically in pigs in the Midwestern U.S., in 1918, coinciding with the human influenza pandemic known as the Spanish flu. Since that time SI has remained o...

journal_title：Advances in virus research

authors： Vincent AL,Ma W,Lager KM,Janke BH,Richt JA

更新日期：2008-01-01 00:00:00

abstract：:Various technological developments have revitalized the approaches employed to study the disease of rabies. In particular, reverse genetics has facilitated the generation of novel viruses used to improve our understanding of the fundamental aspects of rabies virus (RABV) biology and pathogenicity and yielded novel con...

journal_title：Advances in virus research

authors： Nadin-Davis SA,Fehlner-Gardiner C

更新日期：2008-01-01 00:00:00

abstract：:Interest in insect small RNA viruses (SRVs) has grown slowly but steadily. A number of new viruses have been analyzed at the sequence level, adding to our knowledge of their diversity at the level of both individual virus species and families. In particular, a number of possible new virus families have emerged. This r...

journal_title：Advances in virus research

authors： Gordon KH,Waterhouse PM

更新日期：2006-01-01 00:00:00

abstract：:For over a decade, phage display has proven to be of immense value, allowing selection of a large variety of genes with novel functions from diverse libraries. However, the folding and modification requirements of complex proteins place a severe constraint on the type of protein that can be successfully displayed usin...

journal_title：Advances in virus research

authors： Mäkelä AR,Oker-Blom C

更新日期：2006-01-01 00:00:00

abstract：:Carcinoma of the uterine cervix, a leading cause of cancer death in women worldwide, is initiated by infection with high-risk types of human papillomaviruses (HPVs). This review summarizes laboratory studies over the past 20 years that have elucidated the major features of the HPV life cycle, identified the functions ...

journal_title：Advances in virus research

authors： DiMaio D,Liao JB

更新日期：2006-01-01 00:00:00

abstract：:Over the past 10 years, a number of molecular amplification assays have been developed for the detection of flaviviruses. Most of these assays utilize the reverse transcriptase-polymerase chain reaction (RT-PCR) as the amplification format with detection by either agarose gel electrophoresis and ethidium bromide stain...

journal_title：Advances in virus research

authors： Lanciotti RS

更新日期：2003-01-01 00:00:00

abstract：:Epidemiological studies indicate that host immunogenetics and history of infection, particularly by viruses, may be a necessary cofactor for the induction of a variety of autoimmune diseases. To date, however, there is no clear-cut evidence, either in experimental animal models or in human autoimmune disease, that sup...

journal_title：Advances in virus research

authors： Miller SD,Katz-Levy Y,Neville KL,Vanderlugt CL

更新日期：2001-01-01 00:00:00

abstract：:HIV integrase consists of three domains, the structures of which have been individually determined by X-ray crystallography or NMR spectroscopy. The core domain, spanning residues 50-212, is responsible for the catalytic activity of the enzyme. The crystal structure of a dimer of this domain shows similarity to other ...

journal_title：Advances in virus research

authors： Esposito D,Craigie R

更新日期：1999-01-01 00:00:00

abstract：:Following infection of cells by herpes simplex virus, the cell nucleus is subverted for transcription and replication of the viral genome and assembly of progeny nucleocapsids. The transition from host to viral transcription involves viral proteins that influence the ability of the cellular RNA polymerase II to transc...

journal_title：Advances in virus research

authors： Knipe DM

更新日期：1989-01-01 00:00:00

abstract：:In the present review we have identified how viruses can alter the host's susceptibility to bacterial infections by altering both environmental conditions in the lung which favor bacterial replication as well as by suppressing the host's defense mechanisms which prevent clearance of the bacteria. In many instances, th...

journal_title：Advances in virus research

authors： Babiuk LA,Lawman MJ,Ohmann HB

更新日期：1988-01-01 00:00:00