abstract：BACKGROUND:Arteriovenous fistulae (AVFs) may remain patent after kidney transplantation (KTx), contributing to maladaptive cardiac remodeling. The flow in AVFs is associated with the diameter of its vessels and thus with the AVF location. The main objective of this study is to assess the influence of AVF location and i...

journal_title：Renal failure

authors： Letachowicz K,Bardowska K,Królicki T,Kamińska D,Banasik M,Zajdel K,Mazanowska O,Madziarska K,Janczak D,Krajewska M

更新日期：2021-12-01 00:00:00

abstract：BACKGROUND:Emerging evidence demonstrates that gut dysbiosis is implicated in the pathogenesis of chronic kidney disease (CKD) with underlying mechanisms involving mucosal and/or systematic immunity or metabolic disorders. However, the profile of gut microbiota in patients with CKD has not been completely explored. ME...

journal_title：Renal failure

authors： Zhao J,Ning X,Liu B,Dong R,Bai M,Sun S

更新日期：2021-12-01 00:00:00

abstract：:Aims: The aim was to determine whether anti-neutrophil cytoplasmic antibody (ANCA)-positive serology in patients with lupus nephritis (LN) is associated with different clinicopathologic features and outcomes.Methods: In our retrospective analysis, 283 patients were enrolled between 2013 and 2018. Thirty-six patients w...

journal_title：Renal failure

authors： Wang S,Shang J,Xiao J,Zhao Z

更新日期：2020-11-01 00:00:00

abstract：:Background: Both soluble suppression of tumorigenicity 2 (sST2) and N-terminal pro-brain natriuretic peptide (NT-proBNP) are promising biomarkers associated with the adverse clinical outcomes of dialysis patients. Our research aims at exploring and comparing the roles of sST2 and NT-proBNP in predicting the short-term...

journal_title：Renal failure

authors： Wang Z,Chen Z,Yu H,Ma X,Zhang C,Qu B,Zhang W,Chen X

更新日期：2020-11-01 00:00:00

abstract：:Transforming growth factor-β1 (TGF-β1) is a crucial factor implicated in the development of renal inflammation and tubulointerstitial fibrosis (TIF). The cytokine interleukin 22 (IL-22) was previously reported to involve in the pathogenesis of chronic inflammatory diseases, however recent studies showed that IL-22 cou...

journal_title：Renal failure

authors： Tang R,Xiao X,Lu Y,Li H,Zhou Q,Kwadwo Nuro-Gyina P,Li X

更新日期：2020-11-01 00:00:00

abstract：AIM:When peritoneal fibrosis (PF) causes ultrafiltration failure in peritoneal dialysis (PD) patients, PD has to be discontinued. Currently, there is no effective way to relieve PF. In this study, we aimed to determine whether miR-15a-5p is involved in PF and to determine the underlying mechanism. METHODS:Six normal r...

journal_title：Renal failure

authors： He Q,Wen L,Wang L,Zhang Y,Yu W,Zhang F,Zhang W,Xiao J,Wen X,Zhao Z

更新日期：2020-11-01 00:00:00

abstract：:Background: Elevated serum levels of sIL-2R are commonly observed in patients undergoing maintenance hemodialysis (MHD). However, the clinical implications in these subjects are unclear. This study is aimed to assess the significance of elevated sIL-2R levels in MHD patients.Methods: A total of 382 MHD patients were f...

journal_title：Renal failure

authors： Chen X,Li Y,Ding X,Zou J,Shen B,Liu Z,Lv W,Cao X,Xiang F

更新日期：2020-11-01 00:00:00

abstract：:Renal ischemia-reperfusion injury is a leading cause of acute kidney injury, but its underlying mechanism remains poorly understood and effective therapies are still lacking. Here, we identified lncRNA XLOC_032768 as a novel target in renal ischemia-reperfusion injury by analyzing differentially expressed genes of the...

journal_title：Renal failure

authors： Zhou X,Li Y,Wu C,Yu W,Cheng F

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to establish a predictive postoperative nomogram for acute kidney injury (AKI) after intracranial aneurysm clipping surgery, in order to early identify patients with high postoperative AKI risk. METHODS:This is a retrospective study, which included patients who underwent intracranial...

journal_title：Renal failure

authors： Zhang P,Guan C,Li C,Zhu Z,Zhang W,Luan H,Zhou B,Man X,Che L,Wang Y,Zhao L,Zhang H,Luo C,Xu Y

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Fabry disease (FD) is an X-linked lysosomal storage disorder caused by the mutation of the GLA gene, encoding the α-galactosidase, which is responsible for the catabolism of neutral glycosphingolipids. Microalbuminuria or low-grade proteinuria, and continuously progressive renal failure are common manifestat...

journal_title：Renal failure

authors： Zhang R,Chen Z,Lang Y,Shao S,Cai Y,You Q,Sun Y,Wang S,Shi X,Liu Z,Guo W,Han Y,Shao L

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:The present study investigated whether hemodialysis (HD) patients exhibit future memory impairment (PM; the capability of remembering to perform expected future actions) and exploring relevant factors of PM task performance. METHODS:Sixty HD patients and 60 healthy controls matched by age are enrolled in the...

journal_title：Renal failure

authors： Wang B,Li M,Tang F,Wang Y,Han Y,Lu W,Zhang L,Zhang L,Ni W,Zhang L,Zhang L

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:The complement system has been recently proposed to play an important role in the pathogenesis of ANCA-associated vasculitis (AAV). This study evaluated the value of serum and kidney deposited C3 in predicting renal outcomes in AAV. METHODS:This was a retrospective study of 47 patients with AAV, who were ca...

journal_title：Renal failure

authors： Chalkia A,Thomas K,Giannou P,Panagiotopoulos A,Hadziyannis E,Kapota A,Gakiopoulou H,Vassilopoulos D,Petras D

更新日期：2020-11-01 00:00:00

abstract：:Background: Complications associated with ureteral anastomosis in kidney transplantation are highly prevalent, despite the development of various types of stents. The current stent materials and placement methods have several limitations. This study attempts to provide an alternative by investigating ureteral anastomo...

journal_title：Renal failure

authors： Wang T,Yu Z,Chen C,Song Y,Zeng X,Su Y,Yi C

更新日期：2020-11-01 00:00:00

abstract：:Introduction: This study aimed to investigate the clinical characteristics, risk factors, and outcomes of infection-related hospitalization (IRH) in patients with lupus nephritis (LN) and ANCA glomerulonephritis after intensive immunosuppressive therapy.Methods: Patients diagnosed with LN or ANCA glomerulonephritis wh...

journal_title：Renal failure

authors： Yin P,Li J,Wen Q,Qiu Y,Liang W,Wang J,Yu J,Zhong Z,Yang X,Yu X,Ye Q,Huang F

更新日期：2020-11-01 00:00:00

abstract：:Vascular calcification (VC) is an important promoter of cardiovascular disease (CVD) in patients undergoing peritoneal dialysis (PD). Several indices can be used to evaluate VC, including the abdominal aortic calcification index (AACI) and carotid artery intima-media thickness (IMT); however, simpler and lesser expens...

journal_title：Renal failure

authors： Yang N,Yang W,Cui W,Zhou D,Du X,Li L

更新日期：2020-11-01 00:00:00

abstract：AIM:Novel coronavirus pneumonia (COVID-19) has become pandemic. It brings serious threat to hemodialysis (HD) patients. Therefore, we carried out a study on the clinical characteristics of HD patients with COVID-19. METHODS:We retrospectively analyzed the data of 31 HD patients with COVID-19. The clinical features of ...

journal_title：Renal failure

authors： Zhang J,Cao F,Wu SK,Xiang-Heng L,Li W,Li GS,Wang J

更新日期：2020-11-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the effects of curcumin in an experimental model of busulfan-induced renal toxicity with emphasis on importance of histological alterations. METHODS:In this study, we utilized 32 adult male Wistar rats (250 ± 10 g). All the animals were divided into four experimental groups ra...

journal_title：Renal failure

authors： Abdollahifar MA,Ebrahimi V,Aliaghaei A,Raoofi A,Khosravi A,Hasani A,Mehdizadeh A,Asadi M

更新日期：2020-11-01 00:00:00

abstract：:Background: Renal interstitial fibrosis is a common pathway of chronic kidney disease to end-stage renal disease, which is characterized by an imbalance between the synthesis and degradation of the collagen-rich extracellular matrix (ECM). While, discoidin domain receptor 2 (DDR2) can be activated when it binds to som...

journal_title：Renal failure

authors： Li X,Bu X,Yan F,Wang F,Wei D,Yuan J,Zheng W,Su J,Yuan J

更新日期：2019-11-01 00:00:00

abstract：:Objective: The present study assesses whether phosphodiesterase type 5 (PDE-5) inhibitor or carnitine exert nephroprotective effects against clinical contrast-induced nephropathy (CIN).Materials and Methods: The present study consisted of three groups of CKD patients. The first group was control group, who were treate...

journal_title：Renal failure

authors： Armaly Z,Artol S,Jabbour AR,Saffouri A,Habashi N,Abd Elkadir A,Ghattas N,Farah R,Kinaneh S,Nseir W

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Intima-Media-Thickness of the carotid artery wall (cIMT) is a strong predictor of cardiovascular (CV) disease. The aim of this study was to investigate the significance of cIMT as an independent prognostic factor for CV morbidity and mortality in patients with chronic kidney disease (CKD) and diabetes mellit...

journal_title：Renal failure

authors： Roumeliotis A,Roumeliotis S,Panagoutsos S,Theodoridis M,Argyriou C,Tavridou A,Georgiadis GS

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The pathogenesis of the development of IgA nephropathy has not been clear up to now. At present, some studies revealed that the mTOR pathway may participate in IgA nephropathy; however, the mechanism has not been systematically studied. In this study, we established an IgAN rat model to investigate the prote...

journal_title：Renal failure

authors： Guo N,Liu S,Bow LM,Cui X,Zhang L,Xu S,Lu S,Tian J

更新日期：2019-11-01 00:00:00

abstract：:Substances toxic to the kidney are legion in the modern world. The sheer number and variety, their mutual interactions and, metabolism within the body are a challenge to research. Moreover, the kidney is especially prone to injury owing to its physiology. Acute kidney injury (AKI) induced by poisonous or primarily nep...

journal_title：Renal failure

authors： Petejova N,Martinek A,Zadrazil J,Teplan V

更新日期：2019-11-01 00:00:00

abstract：:Objectives: To improve the mouse model of relief for unilateral ureteral obstruction (RUUO) and explore the pathological process of renal fibrosis after the obstruction was relieved. Methods: C57BL/6 mice in model group were randomly divided into RUUO group, improved RUUO group, and UUO group. After leaving Unilateral...

journal_title：Renal failure

authors： Song J,Liu J,Luo J,Zhang Q,Xia Y,Shao Q,Sun C,Jiang C,Zhang M,Zhu W

更新日期：2019-11-01 00:00:00

abstract：:Objective: To study the efficacy and safety of sustained low-efficiency diafiltration (SLEDf) versus hemodialysis (HD) for patients with wasp stings who developed stage III acute kidney injury (AKI). Methods: We retrospectively analyzed the clinical data of consecutive patients who developed AKI following wasp stings....

journal_title：Renal failure

authors： Deng YY,Shen JM,Mao YN,Gou R,Li WW,Ye TT

更新日期：2019-11-01 00:00:00

abstract：:The use of colistin in the treatment of multidrug-resistant Gram-negative bacterial infections is restricted due to nephrotoxicity. We investigated the effects of aged black garlic extract (ABGE) on colistin-induced kidney injury in rats. Rats were assigned to four groups. Normal saline was intraperitoneally and intra...

journal_title：Renal failure

authors： Lee TW,Bae E,Kim JH,Jang HN,Cho HS,Chang SH,Park DJ

更新日期：2019-11-01 00:00:00

abstract：:Purpose: Typically, IgA nephropathy is a slowly progressive type of glomerulonephritis. High-grade proteinuria and hypertension are predictors of reduced kidney function. However, we found some normotensive patients with mild proteinuria could exhibit impaired renal function at the time of IgAN diagnosis. We therefore...

journal_title：Renal failure

authors： Tan M,Fang J,Xu Q,Zhang C,Zou G,Wang M,Li W

更新日期：2019-11-01 00:00:00

abstract：:Objectives: Diffuse enlargements of arteriovenous dialysis fistulas customarily attributed to either excessive arterial inflow or central outflow stenosis. The relationship between volume status and clinically enlarged (arteriovenous) fistula (CEF) formation in end-stage renal disease (ESRD) patients is not well under...

journal_title：Renal failure

authors： Tapolyai M,Faludi M,Berta K,Forró M,Zsom L,Pethő ÁG,Rosivall L,Fülöp T

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:We investigate the mechanism of neutrophil/lymphocyte ratio (NLR) elevation, a useful prognostic marker in patients with cardiovascular diseases (CVDs). METHODS:In this clinical study, we retrospectively searched for factors associated with NLR elevation in cardiovascular outpatients. In animal experiments u...

journal_title：Renal failure

authors： Ito S,Ohno Y,Tanaka T,Kobuchi S,Ayajiki K,Manabe E,Masuyama T,Jun-Ichi S,Tsujino T

更新日期：2019-11-01 00:00:00

abstract：:Although sudden sensorineural hearing loss (SSNHL) affects chronic kidney disease (CKD) patients more frequently than non-CKD patients, few reports have described SSNHL in dialysis patients. We aimed to review the characteristics of SSNHL in chronic dialysis patients and evaluate treatment responses to steroid therapy...

journal_title：Renal failure

authors： Kang SM,Lim HW,Yu H

更新日期：2018-11-01 00:00:00

abstract：INTRODUCTION:Dyslipidemia is one of the onset and risk factors of chronic kidney disease and renal function drop is seen in lipoprotein abnormal animal models. However, the detailed molecular mechanism of renal lipotoxicity has not been clarified. Therefore, the present study aimed to investigate the influence of chole...

journal_title：Renal failure

authors： Honzumi S,Takeuchi M,Kurihara M,Fujiyoshi M,Uchida M,Watanabe K,Suzuki T,Ishii I

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Previous studies have shown that MPO -463G > A (rs2333227) might be associated with chronic kidney disease (CKD) susceptibility, but sample sizes of those studies are relatively small. Hence, we decided to perform a meta-analysis to evaluate the association. Methods/main results: Two investigators ...

journal_title：Renal failure

authors： Qin J,Xing J,Li W,Zhang K,Wu Z

更新日期：2018-11-01 00:00:00

abstract：:In kidney disease, inflammation and lipid dysmetabolism are often associated together, however, the effect and mechanism of inflammatory mediators and lipid dysmetabolism on kidney damage is still unclear. In this study, Wistar rats were randomized into four groups: normal diet + saline (Group N), high-fat diet (HF)+ ...

journal_title：Renal failure

authors： Wang Z,Huang W,Li H,Tang L,Sun H,Liu Q,Zhang L

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVES:Whether uric acid levels were associated with the progression of chronic kidney disease (CKD) remained controversial. This meta-analysis was aimed to assess the effect of lowering serum uric acid therapy on the progression of CKD to clarify the role of uric acid in the progression of CKD indirectly. METHODS...

journal_title：Renal failure

authors： Liu X,Zhai T,Ma R,Luo C,Wang H,Liu L

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) often have CD4+ regulatory T cells (Tregs) dysfunction and chronic inflammation. We aim to investigate the effect, function, and related mechanism of low-dose IL-2 on CD4+ regulatory T cells expansion in vitro from patients with CKD. METHODS:A total of 148 newly di...

journal_title：Renal failure

authors： Li Y,Liu X,Wang W,Wang S,Zhang J,Jiang S,Wang Y,Li L,Li J,Zhang Y,Huang H

更新日期：2018-11-01 00:00:00

abstract：:Left ventricular hypertrophy (LVH) is a common abnormality in hemodialysis (HD) patients. Mitochondrial dysfunction contributes to the progression of LVH. As an inner mitochondrial membrane structural protein, mitofilin plays a key role in maintaining mitochondrial structure and function. The aim of this study was to ...

journal_title：Renal failure

authors： Wu QS,He Q,He JQ,Chao J,Wang WY,Zhou Y,Lou JZ,Kong W,Chen JF

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:The association between poor intraoperative glycemic control and postoperative acute kidney injury (AKI) in adult cardiac surgery has been observed, but data in the pediatrics remain unknown. We performed a hypothesis that intraoperative hyperglycemia and/or wider glycemic fluctuation were associated with the...

journal_title：Renal failure

authors： Hu GH,Duan L,Jiang M,Zhang CL,Duan YY

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Interleukin 17 (IL-17) plays an important role in the pathogenesis of autoimmune diseases and might be associated with IgA nephropathy (IgAN). This study aimed to investigate the effect of IL-17 on autoimmune pathogenesis in IgA nephropathy. METHODS:DAKIKI cells were cultured and stimulated with IL-17 to pe...

journal_title：Renal failure

authors： Lin JR,Wen J,Zhang H,Wang L,Gou FF,Yang M,Fan JM

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:To observe effectiveness and renal safety of long-term low-dose cyclosporine in idiopathic membranous nephropathy (IMN). METHODS:Sixty-eight patients were enrolled in this prospective cohort study. Renal endpoint was defined as a decrease in eGFR ≥50% from baseline and a development of eGFR ≤60 ml/min/1.73m...

journal_title：Renal failure

authors： Yu X,Ruan L,Qu Z,Cui Z,Zhang Y,Wang X,Meng L,Liu X,Wang F,Zhang Y,Liu G,Yang L

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Timely diagnosis of invasive fungal infections (IFI) in renal transplant (RT) patients on immunosuppression is often difficult, jeopardizing their life and graft. We reported IFI and their causative fungal agents in post-RT patients. MATERIALS AND METHODS:This was a retrospective 6-year clinical study carri...

journal_title：Renal failure

authors： Patel MH,Patel RD,Vanikar AV,Kanodia KV,Suthar KS,Nigam LK,Patel HV,Patel AH,Kute VB,Trivedi HL

更新日期：2017-11-01 00:00:00

abstract：:This study was aimed to investigate the therapeutic potential of coenzyme Q10 and its combination with sitagliptin in experimentally induced diabetic nephropathy. The diabetic rats were treated with coenzyme Q10 or sitagliptin and their concomitant administration. Various parameters of renal function like serum creati...

journal_title：Renal failure

authors： Maheshwari R,Balaraman R,Sen AK,Shukla D,Seth A

更新日期：2017-11-01 00:00:00