Interleukin-22 attenuates renal tubular cells inflammation and fibrosis induced by TGF-β1 through Notch1 signaling pathway.

abstract：OBJECTIVE:To investigate the effect of urokinase-type plasminogen activator (uPA) on mesangial matrix in the kidney of diabetic rats and its related mechanisms. METHODS:Diabetic Sprague-Dawley (SD) rats induced by intraperitoneal injection of streptozotocin (STZ) were randomly and evenly divided into two groups: DM + ...

journal_title：Renal failure

authors： Cheng H,Chen C,Wang S

更新日期：2014-09-01 00:00:00

abstract：:TGF-beta1 has been demonstrated to be up-regulated in response to ischemic events both in animal models and in man. Demonstration of this up-regulation in the kidney following experimentally induced acute renal failure and in renal transplants complements similar findings in coronary and cerebral ischemia. Activation ...

journal_title：Renal failure

authors： Docherty NG,Pérez-Barriocanal F,Balboa NE,López-Novoa JM

更新日期：2002-07-01 00:00:00

abstract：:N-acetylglucosaminidase (NAG) is a lysosomal enzyme produced by renal proximal tubular cells and has been widely used as a marker, which indicates a degree of renal tubular damage. An increase in urinary NAG excretion is though to result from the renal tubular damage. The aim of this study was to evaluate whether even...

journal_title：Renal failure

authors： Fujita H,Narita T,Morii T,Shimotomai T,Yoshioka N,Kakei M,Ito S

更新日期：2002-01-01 00:00:00

abstract：:Diabetic nephropathy (DN) is a serious complication of diabetes with a poorly defined etiology and limited treatment options. Early intervention is a key to preventing the progression of DN. Dynamin-related protein 1 (DRP1) regulates mitochondrial morphology by promoting its fission and is involved in the pathogenesis...

journal_title：Renal failure

authors： Zhang L,Ji L,Tang X,Chen X,Li Z,Mi X,Yang L

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND/AIM:There is little information on the development of anemia in the early stages of chronic kidney disease. The aim of this study was to analyze the onset of renal anemia in a cohort of initially nonanemic chronic kidney disease patients followed up in nephrology clinics. METHODS:This epidemiological, prosp...

journal_title：Renal failure

authors： Portolés J,Castelao AM,Gorriz JL,Tato AM,de Alvaro F

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Prolonged corticosteroid (CS) use induces osteoporosis; the pathogenesis of this condition is multifactorial and includes CS-induced hypercalciuria. We investigated the course of hypercalciuria and related markers of bone metabolism parameters during and after the CS treatment. MATERIALS AND M...

journal_title：Renal failure

authors： Duzen O,Erkoc R,Begenik H,Soyoral YU,Aldemir MN

更新日期：2012-01-01 00:00:00

abstract：:Creation of arteriovenous fistula (AVF) may lead to left ventricle hypertrophy and predispose for development or worsening of heart failure. It was postulated to reduce access blood flow if exceeded 2 L/min or cardiac index was higher than 3.0 L/min/m(2). Numbers of techniques decreasing flow were described. The major...

journal_title：Renal failure

authors： Letachowicz K,Kusztal M,Gołębiowski T,Letachowicz W,Weyde W,Klinger M

更新日期：2016-08-01 00:00:00

abstract：:Although hemodialysis (HD) patients could develop vancomycin-resistant enterococci (VRE) infection, limited studies of VRE-related peritoneal dialysis (PD) peritonitis have been reported. Here, we document a patient who developed peritonitis for the first time with VRE infection after shifting from HD to PD over 4 wee...

journal_title：Renal failure

authors： Chang CM,Liang CC,Yeh HC,Yang YF,Wang IK,Lin HH,Huang CC

更新日期：2010-01-01 00:00:00

abstract：:Abnormal glucose metabolism in uremia may result from a complex interplay between decreased insulin secretion and insulin resistance. Recent studies report beneficial effect of biotin administration in glucose metabolism in diabetic animals and in a small number of patients with diabetes mellitus. The aim of the prese...

journal_title：Renal failure

authors： Koutsikos D,Fourtounas C,Kapetanaki A,Agroyannis B,Tzanatos H,Rammos G,Kopelias I,Bosiolis B,Bovoleti O,Darema M,Sallum G

更新日期：1996-01-01 00:00:00

abstract：:Incidence of acute kidney injury (AKI) in patients with pyogenic liver abscess is rare. In our study we found AKI in 32.6% of patients with liver abscess. Majority of the patients were in their fifties and sixties. As per acute kidney injury network trial criteria, renal failure was in stage 1 in 26.6%, stage 2 in 40%...

journal_title：Renal failure

authors： Sriramnaveen P,Sridhar A,Sandeep Y,Krishnakishore C,Sainaresh V,Manjusha Y,Sivakumar V

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND AIM:Trendelenburg positioning (TP) is a common approach used during internal jugular vein (IJV) cannulation. No evidence indicates that TP significantly increases the cross-sectional area (CSA) of the IJV or decreases the overlap between the carotid artery (CA) and the IJV in dialysis patients. The prima...

journal_title：Renal failure

authors： Nayman A,Onal IO,Apiliogullari S,Ozbek S,Saltali AO,Celik JB,Temizoz O,Celik G

更新日期：2015-01-01 00:00:00

abstract：:Ten-Eleven Translocation (TET) proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytonsie (5hmC). Our recent work found a decline in global 5hmC level in mouse kidney insulted by ischemia reperfusion (IR). However, the genomic distribution of 5hmC in mouse kidney and its relationship with gene expression remai...

journal_title：Renal failure

authors： Wang H,Huang N,Liu Y,Cang J,Xue Z

更新日期：2016-07-01 00:00:00

abstract：:Multiple myeloma (MM) is a common malignancy that often results in many kinds of kidney injuries for the abnormal monoclonal immunoglobulin. Here, we present an IgG-kappa type MM case accompanied by renal IgA deposition combined with IgG-kappa. The patient was treated with prednisone plus mycophenolate mofetil, and go...

journal_title：Renal failure

authors： Wang F,Xing T,Li J,Zhang ZG,Wang N

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is a world-wide public health problem. Hypertension is both a cause and a complication of CKD, and a risk factor for progression of kidney disease. The effect of salt intake on blood pressure (BP) and the salt sensitivity in non-dialysis patients with CKD were studied. METHODS:O...

journal_title：Renal failure

authors： Meng L,Fu B,Zhang T,Han Z,Yang M

更新日期：2014-04-01 00:00:00

abstract：INTRODUCTION:Sleep disturbances and cardiovascular autonomic dysfunction are major complications of hemodialysis (HD). The goal of this study is to identify clinical, heart rate variability (HRV) or laboratory parameters that are independently associated with subjective sleep quality. PATIENT AND METHODS:Forty-six sta...

journal_title：Renal failure

authors： Wei CY,Chung TC,Wu SC,Chung CF,Wu WP

更新日期：2011-01-01 00:00:00

abstract：:Studies were performed to reexamine the response of erythropoietin (Epo) production to acute hypoxic stimuli in patients with end-stage renal disease (ESRD). In the absence of acute bleeding or hypoxia, the serum Epo level in ESRD was similar to that of normal subjects despite severe anemia. In 11 dialysis patients wi...

journal_title：Renal failure

authors： Kato A,Hishida A,Kumagai H,Furuya R,Nakajima T,Honda N

更新日期：1994-01-01 00:00:00

abstract：:We investigated the mechanism of impaired serum opsonic activity in patients suffering from chronic renal failure (CRF). Prehemodialysis pooled serum from CRF patients was fractionated using Sephadex G-50 gel chromatography, and the effects of the obtained fractions on serum opsonic activity were examined using lumino...

journal_title：Renal failure

authors： Kikuchi T,Nigawara K,Sugawara K,Nakaji S,Abe T,Satoh H

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:In this study, we compared predialysis and dialysis patients with the controls in terms of insulin resistance and evaluated the association with inflammation that is a risk factor for cardiovascular disease. MATERIALS AND METHODS:A total of 134 non-diabetic patients with controls (n=33), predialysis (n=29) a...

journal_title：Renal failure

authors： Akalın N,Köroğlu M,Harmankaya Ö,Akay H,Kumbasar B

更新日期：2015-03-01 00:00:00

abstract：INTRODUCTION:End-stage renal disease is the most debilitating condition for patients with renal diseases. Cardiovascular disease is the leading cause of death in these patients. It has been shown that nitric oxide (NO) increases in renal failure and hemodialysis patients and could be correlated with cardiovascular dise...

journal_title：Renal failure

authors： Ansarin K,Toufan M,Namdar H,Etemadi J,Habibzadeh A,Valinejad M,Shoja MM,Ghabili K

更新日期：2014-02-01 00:00:00

abstract：:Chronic kidney disease (CKD) is a world-wide public health problem. The purpose of this study was to identify the role of some controversial potential risk factors in development of CKD. "Community Complex Health Screening" is a large-scale, free, health program for individuals ≥40 years of age that has been available...

journal_title：Renal failure

authors： Hsu YC,Lee PH,Lei CC,Shih YH,Lin CL

更新日期：2014-04-01 00:00:00

abstract：:Paraproteins or monoclonal proteins are the result of clonal B-cell or plasma cell proliferation of a malignant, premalignant or non-malignant nature. Monoclonal proteins may consist of intact immunoglobulin molecules or of heavy or light chains only. Depending on their rate of production and/or secretion they may acc...

journal_title：Renal failure

authors： Maniatis A

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:A unique form of postinfectious glomerulonephritis (PIGN) with IgA-dominant deposition mimicking IgA nephropathy has been increasingly reported. METHODS:We compared the clinical and histological features of 12 patients with postinfectious IgA-dominant glomerulonephritis to 134 patients with idiopathic IgA n...

journal_title：Renal failure

authors： Wen YK,Chen ML

更新日期：2010-06-01 00:00:00

abstract：AIM:To investigate the effects of lentivirus-mediated shRNA targeting collagen type I on the mesangial cells of rats and the feasibility of lentivirus-mediated shRNA delivery through renal parenchyma injection. METHODS:Anti-collagen type I shRNA lentiviral vector was constructed, and rat mesangial cells were transfect...

journal_title：Renal failure

authors： Zhou C,Shan Y,Zhao H,He P

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Renal lymphangiectasia is rarely reported benign renal disorder of lymphatic malformation. Though found incidentally; it presents with nonspecific symptoms and shows characteristic findings in radiological imaging studies. AIM:Here, we report eight patients with symptoms, laboratory and imaging findings com...

journal_title：Renal failure

authors： Pandya VK,Sutariya HC,Gandhi SP,Khemchandani SI,Patel HV,Shah MK

更新日期：2017-11-01 00:00:00

abstract：AIM:Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) are implicated in many fibrotic diseases, including renal fibrosis. Whether Ginsenoside-Rg1 (G-Rg1) could attenuate renal fibrosis via suppression of ER stress and UPR has not been reported. The aim of this study was to explore the effect of G-Rg...

journal_title：Renal failure

authors： Li SS,Ye JM,Deng ZY,Yu LX,Gu XX,Liu QF

更新日期：2015-06-01 00:00:00

abstract：:The role of the kidney in the control of blood pressure has been convincingly demonstrated by several studies. Recent evidence has suggested that subtle acquired tubulointerstitial injury may cause a defect in sodium excretion function, thus leading to salt-sensitive hypertension. There are no reports, however, examin...

journal_title：Renal failure

authors： de Magalhães Sartim R,Fantinato Menegon L,de Almeida AR,Rocha Gontijo JA,Aline Boer P

更新日期：2006-01-01 00:00:00

abstract：:During embryonic life, renal morphogenesis is characterized by a defined period of intense cellular activity, inductive-transformation of undifferentiated cells to polarized epithelia, in-growth of capillaries into an intricate parenchymal epithelial-mesenchymal mass, and finally the maturation into an organ with dive...

journal_title：Renal failure

authors： Wallner EI,Kumar A,Carone FA,Kanwar YS

更新日期：1998-03-01 00:00:00

abstract：:The concentrations of urea, creatinine, and uric acid were measured in edema fluid and plasma during hemodialysis and 18 h after hemodialysis. The concentrations of these solutes in plasma were 15-17% lower than in the edema fluid after hemodialysis. Eighteen hours after hemodialysis, however, the concentrations in pl...

journal_title：Renal failure

authors： Shirai D,Kajimoto Y,Ochi S,Tanaka Y,Wada A,Yano F,Izumi M,Fujita Y,Nakahama H

更新日期：1992-01-01 00:00:00

abstract：AIM:Returning to society plays an important role in improving the quality of life in maintenance hemodialysis (MHD) patients, and retention of employment is one of the core enablers. The study is to assess the employment status and to determine the variables for unemployment in Chinese MHD patients. METHODS:Prevalent ...

journal_title：Renal failure

authors： Huang B,Lai B,Xu L,Wang Y,Cao Y,Yan P,Chen J

更新日期：2017-11-01 00:00:00

abstract：:This article reviews our experience with 111 pediatric patients following open-heart surgery over 1-year period. Peritoneal dialysis was required in 34 of 111 children (30.6%). We randomly selected 33 patients who did not require peritoneal dialysis as control group. The indications of dialysis were oligoanuria and/or...

journal_title：Renal failure

authors： Baskin E,Gulleroglu KS,Saygili A,Aslamaci S,Varan B,Tokel K

更新日期：2010-01-01 00:00:00