abstract：:The current in-vivo study was premeditated to uncover the protective role of ezetimibe (EZ) against advanced glycation endproducts (AGEs)-related pathologies in experimental diabetes. Our results showed that EZ markedly improved the altered biochemical markers of diabetes mellitus (DM) (FBG, HbA1c, insulin, microalbum...

journal_title：Archives of physiology and biochemistry

authors： Nabi R,Alvi SS,Shah A,Chaturvedi CP,Faisal M,Alatar AA,Ahmad S,Khan MS

更新日期：2021-01-29 00:00:00

abstract：OBJECTIVE:In the present study, we evaluated the effect of biochanin A (BCA) on high-fat diet (HFD)-induced obesity cardiomyopathy. METHODS:BCA (10 mg/kg body weight) was administered to HFD-induced obese rats for 30 days, and its effect on anthropometrical, morphological, plasma cardiac, and inflammatory biomarkers, ...

journal_title：Archives of physiology and biochemistry

authors： A JIR,Uddandrao VVS,G S,G S,P C,S S,P T,P P S,Vadivukkarasi S

更新日期：2021-01-20 00:00:00

abstract：AIMS AND BACKGROUND:Obesity is recognised as a significant public health burden worldwide. Recently the cross-talk between gut microbiota and obesity has attracted much attention. To that end, Akkermansia muciniphila has been proposed as a promising microbe to manage obesity. In the present systematic review, we evalua...

journal_title：Archives of physiology and biochemistry

authors： Roshanravan N,Bastani S,Tutunchi H,Kafil B,Nikpayam O,Mesri Alamdari N,Hadi A,Sotoudeh S,Ghaffari S,Ostadrahimi A

更新日期：2021-01-15 00:00:00

abstract：:Diabetic nephropathy (DN) is one of the devastating complications in diabetes mellitus (DM). Glucagon-like peptide-1 (GLP-1) is one of the incretins secreted from L cells in the intestine. Crocin (a carotenoid component of saffron) has antioxidants properties. We investigated the renal effects of Exendin-4 as a GLP-1 ...

journal_title：Archives of physiology and biochemistry

authors： Amin SN,El-Gamal EM,Rashed LA,Kamar SS,Haroun MA

更新日期：2020-12-07 00:00:00

abstract：:The objective of the study was to investigate the association of blood glucose and lipid profile parameters with cognitive impairment in schizophrenia. A total of 200 schizophrenia patients and 169 controls were enrolled in the study. Blood glucose and lipid profile were estimated in all the subjects. Cognition was as...

journal_title：Archives of physiology and biochemistry

authors： Nandeesha H,Keshri N,Rajappa M,Menon V

更新日期：2020-11-03 00:00:00

abstract：:Present study investigated the interactive effect of swimming training and fenugreek on glycemic index and lipid profile of diabetic rats. Forty-eight diabetic rats were randomly assigned to (1) control(C), (2) training(T), (3) fenugreek(F), and (4) training + fenugreek(T + F) groups and 12 healthy rats were placed in...

journal_title：Archives of physiology and biochemistry

authors： Hosseini SA,Hamzavi K,Safarzadeh H,Salehi O

更新日期：2020-10-05 00:00:00

abstract：AIM:The objective of this study was to evaluate the probable mechanism of action of Biochanin A (BCA) on high-fat diet-induced insulin resistance mice. METHODS:Twenty-four male C57/BL/6J mice were divided into two and fed either control diet or a high fat-high diet (HFD). After 6 weeks, mice were grouped into: Control...

journal_title：Archives of physiology and biochemistry

authors： Arjunan S,Thangaiyan R,Balaraman D

更新日期：2020-09-29 00:00:00

abstract：CONTEXT:Metabolic syndrome (MetS) is a clustering of several physiological alterations. OBJECTIVE:This study was designed to evaluate the effects of MetS on rats spermatogenesis and steroidogenesis. MATERIALS AND METHODS:We developed a MetS rodent model using high-sugar and high-fat diet. RESULTS:MetS rats showed se...

journal_title：Archives of physiology and biochemistry

authors： Rahali D,Dallagi Y,Hupkens E,Veegh G,Mc Entee K,Asmi ME,El Fazaa S,El Golli N

更新日期：2020-09-04 00:00:00

abstract：AIM:A high-fat diet (HFD) can lead to obesity and related metabolic disorders. This study evaluated the preventive efficacy of myricetin derivative-rich fraction (MD) from Syzygium malaccense leaf extract against HFD-induced obesity, hyperglycaemia, and oxidative stress in C57BL/6J mice. METHODS:HFD-fed mice were admi...

journal_title：Archives of physiology and biochemistry

authors： Nallappan D,Ong KC,Palanisamy UD,Chua KH,Kuppusamy UR

更新日期：2020-08-19 00:00:00

abstract：:This present study investigated the antioxidative and antidiabetic properties of kolaviron by analysing its inhibitory effect on key metabolic activities linked to T2D, in vitro and ex vivo. Kolaviron significantly inhibited α-glucosidase and α-amylase activities, and intestinal glucose absorption dose-dependently, wh...

journal_title：Archives of physiology and biochemistry

authors： Salau VF,Erukainure OL,Koorbanally NA,Islam MS

更新日期：2020-08-17 00:00:00

abstract：:The authors conducted this meta-analysis to robustly estimate relationships between polymorphisms in VDR gene and the risk of osteoporosis by integrating the results of previous works. Medline, Embase, Wanfang, VIP and CNKI were searched thoroughly for eligible studies, and 73 genetic association studies were finally ...

journal_title：Archives of physiology and biochemistry

authors： Jiang LL,Zhang C,Zhang Y,Ma F,Guan Y

更新日期：2020-08-06 00:00:00

abstract：:This study investigated the effect of eight weeks of aerobic training (AT) combined with silymarin (S)consumption on glycemic indices and liver enzymes in men with type 2 diabetes (T2D). In this clinical trial, 60 middle-aged male volunteers were randomly divided into 4 groups, including: (1) C + placebo(C) (2) AT + p...

journal_title：Archives of physiology and biochemistry

authors： Ghalandari K,Shabani M,Khajehlandi A,Mohammadi A

更新日期：2020-08-04 00:00:00

abstract：OBJECTIVES:Examine the diagnostic role of serum exosomal RAB27A mRNA in lung cancer and evaluate the relation of LncRNAs to lung cancer in association to RAB27A mRNA in Egyptian population. METHODS:Exosomal RNA-based biomarkers RAB27A mRNA and Lnc-RNA-RP11-510M2.10 were selected based on bioinformatic methods, followe...

journal_title：Archives of physiology and biochemistry

authors： Mohamed Gamal El-Din G,Ibrahim FK,Shehata HH,Osman NM,Abdel-Rahman OM,Ali M

更新日期：2020-07-13 00:00:00

abstract：:Context: Recent surveys have shown an association between proprotein convertase subtilisin/kexin type 9 (PCSK9) and oxidative stress.Objective: In this investigation, the effect of evolocumab an anti-PCSK9 antibody was assessed against oxidative damage caused by hydrogen peroxide (H2O2) in human umbilical vein endothe...

journal_title：Archives of physiology and biochemistry

authors： Safaeian L,Mirian M,Bahrizadeh S

更新日期：2020-07-03 00:00:00

abstract：:Aims: Regarding the fact that up-regulation of miR-195 in diabetic hearts has a potential role in diabetic cardiomyopathy, the present study investigated whether continuous endurance training (CET) and high-intensity interval training (HIIT) reduces miR-195 expression and which exercise is effective in this regard.Met...

journal_title：Archives of physiology and biochemistry

authors： Khakdan S,Delfan M,Heydarpour Meymeh M,Kazerouni F,Ghaedi H,Shanaki M,Kalaki-Jouybari F,Gorgani-Firuzjaee S,Rahimipour A

更新日期：2020-07-01 00:00:00

abstract：:Circadian rhythms affect a variety of physiological processes. Disruption of circadian rhythms causes many diseases, most of which are associated with inflammation. Disruption of circadian rhythms has a detrimental impact on the function of immune system. It is common to find that circulatory LPS are increased. LPS in...

journal_title：Archives of physiology and biochemistry

authors： Luo X,Yang X,Yang Y,Li H,Cui H,Cao X

更新日期：2020-07-01 00:00:00

abstract：:Background: Rheumatoid arthritis (RA) is a joint destructive disorder. This study aimed to assess lncRNA MEG3 expression and its variant rs941576 in Egyptian patients with RA.Subjects and methods: 100 RA patients and 100 healthy individuals were enrolled in the study. Quantitative PCR was used for expression analysis ...

journal_title：Archives of physiology and biochemistry

authors： Wahba AS,Ibrahim ME,Mesbah NM,Saleh SM,Abo-Elmatty DM,Mehanna ET

更新日期：2020-07-01 00:00:00

abstract：:The consumption of high calorie-content diets is the first cause of obesity, probably the main health issue worldwide; however, the experimental evidences for evaluating the differential metabolic modifications of high-sucrose or high-fat diets are scare. We evaluated the metabolic outcomes of the obesity induced by t...

journal_title：Archives of physiology and biochemistry

authors： Gómez-Crisóstomo NP,De la Cruz-Hernández EN,Méndez Méndez ER,Hernández-Landero MF,Camacho Liévano JU,Martínez-Abundis E

更新日期：2020-07-01 00:00:00

abstract：:We aimed to firstly examine the effects of nutrition and exercise training on irisin, Sema-3E, biochemical and inflammatory parameters in obese patients. This study was conducted using 37 individuals were divided into three groups according to body mass index (BMI) as non-obese, 1nd degree and 2nd degree obese individ...

journal_title：Archives of physiology and biochemistry

authors： Sezgin G,Kar F,Uslu S

更新日期：2020-06-22 00:00:00

abstract：:The dysregulation of microRNA expression is significantly associated with the initiation and development of CRC. miR-124 is markedly downregulated in colorectal cancer. In the present study, the effects of methylation, over expression and downregulation of miR-124 and its target gene DNMT3B on the proliferation, migra...

journal_title：Archives of physiology and biochemistry

authors： Shahmohamadnejad S,Nouri Ghonbalani Z,Tahbazlahafi B,Panahi G,Meshkani R,Emami Razavi A,Shokri Afra H,Khalili E

更新日期：2020-06-18 00:00:00

abstract：:Several studies have suggested that fibroblast-like synoviocytes (FLSs) and miRNAs are implicated in the pathogenesis of rheumatoid arthritis (RA). This study was aimed to evaluate the function of miR-6089 in the regulation of RA-FLSs. The levels of miR-6089 were detected to be significantly lower in the synovial tiss...

journal_title：Archives of physiology and biochemistry

authors： Lin S,Wang S,Zhang Z,Lu Y,Yang M,Chen P,Chen L,Wang M

更新日期：2020-06-17 00:00:00

abstract：:Context: Exposure to Electomagnetic radiation fields of cell phones causes thyroid dysfunction and a previous study revealed that nesfatin-1 may affect functions of the thyroid gland.Objective: To study the role of nesfatin-1 on functions of rat's thyroid gland exposed to EMRF.Materials and methods: Thirty adult male ...

journal_title：Archives of physiology and biochemistry

authors： Hussien NI,Mousa AM,Shoman AA

更新日期：2020-06-17 00:00:00

abstract：:Background: The microRNAs have come up as crucial mediators of energy balance and metabolic control. CD36 is potential biomarker of obesity and metabolic syndrome. This study investigates the concentration of miR-146a and miR-21 and CD 36 in blood samples of obese and healthy young participants. We assessed the associ...

journal_title：Archives of physiology and biochemistry

authors： Benbaibeche H,Hichami A,Oudjit B,Haffaf EM,Kacimi G,Koceïr EA,Khan NA

更新日期：2020-06-13 00:00:00

abstract：:Septic encephalopathy (SE) is a devastating consequence of sepsis, a hyper-triggered host response against infectious challenge, which ultimately leads to brain damage. The present study examined whether sevoflurane (SVF), a volatile anaesthetic, can counteract the perturbation of homeostasis in a caecal ligation and ...

journal_title：Archives of physiology and biochemistry

authors： Chen H,Peng Y,Wang L,Wang X

更新日期：2020-06-13 00:00:00

abstract：:Background: We investigated whether the anti-inflammatory and antioxidant agent, resveratrol can inhibit type 2 diabetes mellitus (T2DM)-induced osteoarthritis (OA) in rats and whether it is associated with the suppression of glycaemia, dyslipidemia and inflammatory and oxidative stress biomarkers.Materials and method...

journal_title：Archives of physiology and biochemistry

authors： Ebrahim HA,Alzamil NM,Al-Ani B,Haidara MA,Kamar SS,Dawood AF

更新日期：2020-06-04 00:00:00

abstract：:The effects of exercise training on oxidative stress in gastrocnemius of rats with pulmonary hypertension were studied. Four groups were established: sedentary control (SC), sedentary monocrotaline (SM), trained control (TC), trained monocrotaline (TM). Exercise was applied for 4 weeks, 5 days/week, 50-60 min/session,...

journal_title：Archives of physiology and biochemistry

authors： Becker CU,Sartório CL,Campos-Carraro C,Siqueira R,Colombo R,Zimmer A,Belló-Klein A

更新日期：2020-05-25 00:00:00

abstract：:Context: Follistatin-like 1 (FSTL1) and apelin exert a favourable effect on energy metabolism.Objective: We examined the effects of acute endurance exercise on the levels of FSTL1 and apelin in the serum and metabolic organs of rats.Methods: Rats were divided into two groups: a sedentary control (CON, n = 8) group and...

journal_title：Archives of physiology and biochemistry

authors： Kon M,Tanimura Y,Yoshizato H

更新日期：2020-05-15 00:00:00

abstract：:Objective: To explore the probable in vitro, in situ and in vivo mechanisms of gallic acid (GA) and p-coumaric acid (PCA) as anti-hyperglycemic agents.Animals and methods: Male albino rats were allocated into four groups, group1 was used as normal control. Group 2 was established as a diabetic control and group3 and 4...

journal_title：Archives of physiology and biochemistry

authors： Abdel-Moneim A,Abd El-Twab SM,Yousef AI,Ashour MB,Reheim ESA,Hamed MAA

更新日期：2020-05-13 00:00:00

abstract：:Background: This study aimed to investigate the association of calorie and carbohydrate intake with tumour grade in early detection of breast cancer (BC) in Iranian women.Materials and methods: This case-control study carried out on 62 women with high grade BC and 93 women with low grade BC. Information about confound...

journal_title：Archives of physiology and biochemistry

authors： Hatami M,Doaei S,Gholamalizadeh M,Mosavi Jarrahi SA,Mirsafa F,Davoodi SH

更新日期：2020-05-06 00:00:00

abstract：:This study investigated the effects of garlic on anxiety- and depression-related behaviors and brain oxidative markers in streptozotocin (STZ)-induced diabetes in rats. Fifty-six male Wistar rats were randomly divided into seven experimental groups (n = 8/group): control, diabetic + saline, diabetic + garlic, diabetic...

journal_title：Archives of physiology and biochemistry

authors： Rahmani G,Farajdokht F,Mohaddes G,Babri S,Ebrahimi V,Ebrahimi H

更新日期：2020-05-01 00:00:00

abstract：:This study aimed to investigate the roles of RPSAP52 in renal failure. Our results showed that RPSAP52 was upregulated in plasma of renal failure patients in comparison to healthy controls. Dual luciferase reporter assay showed that RPSAP52 could interact with miR-423-5p, while overexpression of RPSAP52 and miR-423-5p...

journal_title：Archives of physiology and biochemistry

authors： Chen J,Zheng Y,Li L

更新日期：2020-04-17 00:00:00

abstract：:Objective: We aimed to determine myo-inositol oxygenase (MIOX) activity in gestational diabetes mellitus (GDM).Material and Methods: The insulin, HbA1c, and MIOX levels of 80 pregnant women were analysed after 75 g OGTT. Group I included patients with no risk factor for GDM, Group II: patients with high risk for GDM, ...

journal_title：Archives of physiology and biochemistry

authors： Kısa B,Sert UY,Celik HK,Candar T,Erol Koç EM,Taşcı Y,Çağlar GS

更新日期：2020-03-19 00:00:00

abstract：:Background: Oxidative stress, has been shown to play an important role in the pathophysiology of cardiac remodelling and heart failure. The aim of study is effect of arginine vasopressin (AVP) on apoptosis of cardiomyocyte via its receptors.Materials and methods: The cell viability effect of AVP in H9C2 cardiomyocytes...

journal_title：Archives of physiology and biochemistry

authors： Ghorbanzadeh V,Jafarpour A,Pirnia A,Pajouhi N,Khaksarian M,Veiskarami S,Nazari A

更新日期：2020-03-06 00:00:00

abstract：:The effectiveness of betulinic acid (B) and PLGA loaded nanoparticles of B (Bnp) against hepatocellular carcinoma (HCC) was established and reported earlier. In continuation of our previous report, the present study described the molecular mechanisms of their antineoplastic responses. In this context, the antineoplast...

journal_title：Archives of physiology and biochemistry

authors： Kumar P,Gautam AK,Kumar U,Bhadauria AS,Singh AK,Kumar D,Mahata T,Maity B,Bera H,Saha S

更新日期：2020-03-06 00:00:00

abstract：:Analysis of miRNAs has a strong potential for the identification of novel prognostic or predictive biomarkers in the serum of AD patients. In this study, we investigated the serum levels of miR-106b as a diagnostic biomarker for AD and evaluate its predictive value for therapeutic response to the drug rivastigmine. Pa...

journal_title：Archives of physiology and biochemistry

authors： Madadi S,Saidijam M,Yavari B,Soleimani M

更新日期：2020-03-06 00:00:00

abstract：:This study investigated the expression and underlying molecular mechanism of CPSF1 in diabetic retinopathy. Streptozotocin (STZ)-induced Sprague-Dawley (SD) rats were employed as a diabetic model, and high-glucose (HG)-induced human retinal vascular endothelial cells （HRVECs）were used as an in vitro experimental model...

journal_title：Archives of physiology and biochemistry

authors： Zhang J,Zhang X,Zou Y,Han F

更新日期：2020-02-12 00:00:00

abstract：:Objectives: The main aim of this study was to investigate the effects of irisin on asprosin, leptin, glucose levels and lipid profile in healthy and obese male and female rats.Methods: Irisin was subcutaneously administered with osmotic minipumps at the dose of 100 ng/kg/day for 28 days and then, the serum levels of a...

journal_title：Archives of physiology and biochemistry

authors： Ozcan S,Ulker N,Bulmus O,Yardimci A,Ozcan M,Canpolat S

更新日期：2020-02-06 00:00:00

abstract：:Arecoline is known to cause endocrine dysfunction. In the current article role of arecoline on pineal-testis activity was investigated in hypothyroid rats induced by propylthiouracil (PTU). PTU treatment caused thyroid dysfunction ultrastructurally with a fall in T3 and T4 levels followed by a rise of thyroid stimulat...

journal_title：Archives of physiology and biochemistry

authors： Saha I,Chakraborty SB,Chatterjee A,Pradhan D,Chatterji U,Maiti BR

更新日期：2020-02-01 00:00:00

abstract：:Adiponectin is the most important adipokine secreted by the adipose tissue. It carries out an important role in setting up the metabolism and improving the function of various organs. Adiponectin in the kidneys prevents degradation of the renal arteries, reduces protein excretion, and improves filtration. This role is...

journal_title：Archives of physiology and biochemistry

authors： Esmaili S,Hemmati M,Karamian M

更新日期：2020-02-01 00:00:00

abstract：:Aim: This study tested the hypothesis that folic acid (FA) modulates biogenic amines and protects the brain against oxidative stress induced by 3-nitropropionic acid (3NPA).Methods: Male Wistar rats received (groups of six) for 5 d: FA (50 mg/kg); 3NPA (10 mg/kg); or FA +3NPA. At last day, rats were sacrificed, and th...

journal_title：Archives of physiology and biochemistry

authors： Calderón Guzmán D,Osnaya Brizuela N,Ortiz Herrera M,Juárez Olguín H,Valenzuela Peraza A,Hernández García E,Barragán Mejía G

更新日期：2020-02-01 00:00:00