abstract：BACKGROUND:The mechanism of left atrial (LA) remodeling is poorly understood. The aim of this longitudinal study was to investigate whether changes in NT-proBNP levels relate to alterations of LA structure and function over time in a multi-ethnic population. METHODS:From the prospective cohort study, the Multi-Ethnic ...

journal_title：American journal of hypertension

authors： Varadarajan V,Ambale-Venkatesh B,Hong SY,Habibi M,Ashikaga H,Wu CO,Chen LY,Heckbert SR,Bluemke DA,Lima JAC

更新日期：2021-01-25 00:00:00

abstract：BACKGROUND:Subjects with renovascular hypertension (RVH) often manifest with metabolic syndrome (MetS) as well. Coexisting MetS and hypertension increases cardiovascular morbidity and mortality, but the mechanisms underlying cardiac injury remain unknown. We hypothesized that superimposition of MetS induces myocardial ...

journal_title：American journal of hypertension

authors： Aghajani Nargesi A,Farah MC,Zhu XY,Zhang L,Tang H,Jordan KL,Saadiq IM,Lerman A,Lerman LO,Eirin A

更新日期：2020-12-05 00:00:00

abstract：BACKGROUND:Increased blood-pressure-variability (BPV) is associated with increased cardiovascular and all-cause mortality in patients with type 2 diabetes mellitus (T2DM). Sodium-glucose-co-transporter-2 (SGLT-2) inhibitors decrease the incidence of cardiovascular events, renal events, and death in this population. Thi...

journal_title：American journal of hypertension

authors： Papadopoulou E,Theodorakopoulou MP,Loutradis C,Tzanis G,Tzatzagou G,Kotsa K,Zografou I,Tsapas A,Karagiannis A,Sarafidis P

更新日期：2020-12-05 00:00:00

abstract：BACKGROUND:Blood pressure (BP) measured in the office setting increases from early through later adulthood. However, it is unknown to what extent out-of-office BP derived via ambulatory BP monitoring (ABPM) increases over time, and which participant characteristics and risk factors might contribute to these increases. ...

journal_title：American journal of hypertension

authors： Bundy JD,Jaeger BC,Huffman MD,Knox SS,Thomas SJ,Shimbo D,Booth Iii JN,Lewis CE,Edwards LJ,Schwartz JE,Muntner P

更新日期：2020-11-17 00:00:00

abstract：BACKGROUND:Nocturnal hypertension is an important phenotype of abnormal diurnal blood pressure (BP) variability and a known risk marker for target organ damage and cardiovascular events. This study aimed to assess the differential BP-lowering effects of esaxerenone vs. eplerenone on nocturnal BP in hypertensive patient...

journal_title：American journal of hypertension

authors： Kario K,Ito S,Itoh H,Rakugi H,Okuda Y,Yoshimura M,Yamakawa S

更新日期：2020-11-09 00:00:00

abstract：:The protein chemerin (tazarotene-induced gene, TIG2; RARRES2) is a relatively new adipokine. Many studies support that circulating chemerin levels associate strongly and positively with body mass index, visceral fat, and blood pressure. Here, we focus on the specific relationship of chemerin and blood pressure with th...

journal_title：American journal of hypertension

authors： Ferland DJ,Mullick AE,Watts SW

更新日期：2020-11-03 00:00:00

abstract：:Hypertension is a common condition that is often seen in patients with diabetes. Both diseases increase the risk of morbidity and mortality from CV events and kidney disease progression. Factors that influence blood pressure (BP) control in diabetes include the persons' genetic background for hypertension and kidney d...

journal_title：American journal of hypertension

authors： Ali W,Bakris GL

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:There is evidence from genome wide association study that single-nucleotide polymorphisms (SNPs) in the 5' end of the uromodulin gene (UMOD) affect uromodulin excretion and blood pressure (BP). Uromodulin is almost exclusively expressed in the thick ascending limb of the loop of Henle (TAL) and its effect on...

journal_title：American journal of hypertension

authors： McCallum L,Brooksbank K,McConnachie A,Aman A,Lip S,Dawson J,MacIntyre IM,MacDonald TM,Webb DJ,Padmanabhan S

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:Recent studies have shown that hyperuricemia may be associated with incident hypertension (HTN). We examined whether serum uric acid (SUA) is a predictor of HTN and target organ damage (TOD) 20 years later in initially healthy middle-aged individuals. METHODS:Participants from the Suivi Temporaire Annuel No...

journal_title：American journal of hypertension

authors： Kanbay M,Girerd N,Machu JL,Bozec E,Duarte K,Boivin JM,Wagner S,Ferreira JP,Zannad F,Rossignol P

更新日期：2020-09-10 00:00:00

abstract：BACKGROUND:Hypertension guidelines recommend home blood pressure monitoring (HBPM) to help achieve blood pressure (BP) control. We hypothesized that HBPM use with a physician recommendation would be associated with lower BP and greater medication adherence. METHODS:We used data from 6,320 adults with hypertension in t...

journal_title：American journal of hypertension

authors： Tang O,Foti K,Miller ER,Appel LJ,Juraschek SP

更新日期：2020-09-10 00:00:00

abstract：BACKGROUND:Liddle syndrome (LS), an autosomal dominant disorder, is a common monogenic hypertension in pediatrics. In this study, we reported a novel SCNN1G variant in a Chinese family with pediatric LS, and conduct a systematic review of epithelial sodium channel (ENaC)-gene-positive LS cases to conclude the clinical ...

journal_title：American journal of hypertension

authors： Fan P,Pan XC,Zhang D,Yang KQ,Zhang Y,Tian T,Luo F,Ma WJ,Liu YX,Wang LP,Zhang HM,Song L,Cai J,Zhou XL

更新日期：2020-07-18 00:00:00

abstract：BACKGROUND:We investigated the effects of percutaneous transluminal renal angioplasty on left ventricular (LV) mass, and the impact of LV mass reduction on outcomes. METHODS:A total of 144 hypertensive patients with renal artery stenosis (RAS) (mean age 69 years; 22.2% fibromuscular dysplasia (FMD)) who underwent angi...

journal_title：American journal of hypertension

authors： Iwashima Y,Fukuda T,Horio T,Kusunoki H,Hayashi SI,Kamide K,Kawano Y,Ishimitsu T,Yoshihara F

更新日期：2020-05-21 00:00:00

abstract：BACKGROUND:As a serious pregnancy-specific condition, preeclampsia (PE) is a serious pregnancy-specific condition characterized by insufficient trophoblastic invasion and shallow placental implantation. Long noncoding RNA uc.187, which is transcribed from an ultra-conserved region is highly expressed in the placental t...

journal_title：American journal of hypertension

authors： Huang J,Qian Y,Cheng Q,Yang J,Ding H,Jia R

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND:Ryanodine receptor (RyR) dysfunction in skeletal muscle (RyR1) leads to malignant hyperthermia, and in cardiac muscle (RyR2) triggers cardiac arrhythmias. We hypothesized that RyR dysfunction in vascular smooth muscle could increase vascular resistance and hypertension, and may contribute to increased atrial...

journal_title：American journal of hypertension

authors： Lee JS,Greco L,Migirov A,Li Y,Gerdes AM,Zhang Y

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND:Despite readily available treatments, control of blood pressure (BP) with population aging remains suboptimal. Further, there are gaps in the understanding of the management of high BP in the aged. We explored antihypertensive treatment and control among elderly hypertensive participants free from overt card...

journal_title：American journal of hypertension

authors： Chowdhury EK,Nelson MR,Ernst ME,Margolis KL,Beilin LJ,Johnston CI,Woods RL,Murray AM,Wolfe R,Storey E,Shah RC,Lockery JE,Tonkin AM,Newman AB,Williamson JD,Abhayaratna WP,Stocks NP,Fitzgerald SM,Orchard SG,Trevaks RE

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Beetroot has attracted much attention because of its blood pressure-lowering properties. Although beetroot contains various nutritional compounds, including inorganic nitrate, some of their physiological properties are not fully understood. In this study, we examined whether betanin, a beetroot component, ha...

journal_title：American journal of hypertension

authors： Tawa M,Masuoka T,Yamashita Y,Nakano K,Ishibashi T

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Central artery reservoir-excess pressure parameters are clinically important but impractical to record directly. However, diastolic waveform morphology is consistent across central and peripheral arteries. Therefore, peripheral artery reservoir-excess pressure parameters related to diastolic waveform morphol...

journal_title：American journal of hypertension

authors： Armstrong MK,Schultz MG,Picone DS,Black JA,Dwyer N,Roberts-Thomson P,Sharman JE

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence and determinants of hypertension in India based on a new definition by the 2017 American College of Cardiology/American Heart Association (2017 ACC/AHA) Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults, and compare prevalence estima...

journal_title：American journal of hypertension

authors： Abariga SA,Khachan H,Al Kibria GM

更新日期：2020-03-13 00:00:00

abstract：BACKGROUND:The optimal schedule for self-monitoring home BP (SMHBP) readings is enormously important in the diagnosis of different phenotypes related to hypertension. The aim of this study was to determine the prognostic capacity of a 3-day SMHBP schedule when using or suppressing the first-day measurements in compilin...

journal_title：American journal of hypertension

authors： Bayó J,Dalfó A,Barceló MA,Saez M,Roca C,Pallozzi J,Coll-De-Tuero G

更新日期：2020-02-22 00:00:00

abstract：BACKGROUND:The association between hypertension (HTN) and inflammatory biomarkers (interleukin-6 [IL-6] and high-sensitivity C-reactive protein [hsCRP]) in HIV-positive persons with CD4+ count >500 cells/mm3 is unknown. METHODS:We studied HTN in participants of the Strategic Timing of AntiRetroviral Treatment (START) ...

journal_title：American journal of hypertension

authors： Ghazi L,Baker JV,Sharma S,Jain MK,Palfreeman A,Necsoi C,Murray DD,Neaton JD,Drawz PE

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:New onset resistant hypertension in a previously stable patient with chronic hypertension should lead to consideration of secondary causes. Electrolyte abnormalities are useful clues for identifying some common causes, especially mineralocorticoid excess. CASE PRESENTATION:We report the case of a 69-year-ol...

journal_title：American journal of hypertension

authors： Klomjit N,Rowan DJ,Kattah AG,Bancos I,Taler SJ

更新日期：2019-11-15 00:00:00

abstract：BACKGROUND:The risk for cardiovascular events increases within hours of near-roadway exposures. We aimed to determine the traffic-related air pollution (TRAP) and biological mechanisms involved and if reducing particulate matter <2.5 µm (PM2.5) inhalation is protective. METHODS:Fifty healthy-adults underwent multiple ...

journal_title：American journal of hypertension

authors： Morishita M,Wang L,Speth K,Zhou N,Bard RL,Li F,Brook JR,Rajagopalan S,Brook RD

更新日期：2019-10-16 00:00:00

abstract：BACKGROUND:Obesity is one of the main determinants of blood pressure. The aim of this study was to evaluate and quantify the relations between the different anthropometric indices and blood pressure (BP) stratified by gender. METHODS:Cross-sectional analyses were performed using data from 2,105 adults from the ESTEBAN...

journal_title：American journal of hypertension

authors： Vallée A,Perrine AL,Deschamps V,Blacher J,Olié V

更新日期：2019-09-24 00:00:00

abstract：BACKGROUND:In chronic kidney disease, intensive systolic blood pressure (SBP) control reduces mortality at a cost of greater acute kidney injury risk. Kidney transplantation involves implantation of denervated kidneys and immunosuppressive medications that increase acute kidney injury risk. The optimal blood pressure (...

journal_title：American journal of hypertension

authors： Malhotra R,Katz R,Weiner DE,Levey AS,Cheung AK,Bostom AG,Ix JH

更新日期：2019-08-14 00:00:00

abstract：BACKGROUND:Increased short-term blood pressure (BP) variability (BPV) in hemodialysis is associated with increased cardiovascular and all-cause mortality. Studies on the impact of BP-lowering interventions on BPV are scarce. This study examined the effect of dry-weight reduction with a lung ultrasound-guided strategy o...

journal_title：American journal of hypertension

authors： Loutradis C,Sarafidis PA,Theodorakopoulou M,Ekart R,Alexandrou ME,Pyrgidis N,Angeloudi E,Tzanis G,Toumpourleka M,Papadopoulou D,Mallamaci F,Zoccali C,Papagianni A

更新日期：2019-07-17 00:00:00

abstract：OBJECTIVE:To determine the effects of orthostatic hypotension (OH) measurement timing on its associations with dizziness, falls, fractures, cardiovascular disease (CVD), and mortality. METHODS:We analyzed OH measurements from the Action to Control Cardiovascular Risk in Diabetes BP trial, which evaluated two blood pre...

journal_title：American journal of hypertension

authors： Juraschek SP,Lipsitz LA,Beach JL,Mukamal KJ

更新日期：2019-06-11 00:00:00

abstract：BACKGROUND:Exaggerated sympathetic cardiovascular (CV) reactivity to stress associates with elevated risk for clinical and preclinical end points of CV disease. It would be useful to identify these individuals, preferably from feasible measurements commonly used in health care. Our study examined the association betwee...

journal_title：American journal of hypertension

authors： Hintsala HE,Kiviniemi AM,Antikainen R,Mäntysaari M,Jokelainen J,Hassi J,Tulppo MP,Herzig KH,Keinänen-Kiukaanniemi S,Rintamäki H,Jaakkola JJK,Ikäheimo TM

更新日期：2019-05-09 00:00:00

abstract：BACKGROUND:Although previous studies have explored the effect of smoking on blood pressure, little is still known about the role of time to first cigarette (TTFC)-an indicator of nicotine dependence-in hypertension. Therefore, we evaluated this association using representative nationwide data. METHODS:Current daily sm...

journal_title：American journal of hypertension

authors： Bae J,Yi YH,Kim YJ,Lee JG,Tak YJ,Lee SH,Hwang HR,Lee SY,Cho YH,Ro EJ

更新日期：2019-01-15 00:00:00

abstract：BACKGROUND:Higher fibroblast growth factor-23 (FGF23) concentrations have been found to be associated with incident heart failure (HF). Experimental data suggest FGF23 directly stimulates myocardial hypertrophy. FGF23 may also enhance renin-angiotensin-aldosterone system activity. Whether FGF23 is associated with incre...

journal_title：American journal of hypertension

authors： Akhabue E,Vu TT,Vaidya A,Michos ED,de Boer IH,Kestenbaum B,Allison M,Szklo M,Ouyang P,Yancy CW,Wolf M,Isakova T,Carnethon MR

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:In uremic animals, vitamin D receptor (VDR) agonists like paricalcitol (Pc) attenuate cardiac hypertrophy, but this effect has not been replicated consistently in humans with chronic kidney disease. Elevated fibroblast growth factor 23 (FGF23) levels cause cardiac hypertrophy with activation of the myocardia...

journal_title：American journal of hypertension

authors： Czaya B,Seeherunvong W,Singh S,Yanucil C,Ruiz P,Quiroz Y,Grabner A,Katsoufis C,Swaminathan S,Abitbol C,Rodriguez-Iturbe B,Faul C,Freundlich M

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Inadequately treated hypertension (HTN) leads to considerable morbidity and mortality. Despite many treatment options, blood pressure (BP) control is suboptimal. Missed opportunities due to the growing complexity of primary care office visits contribute. Electronic health records (EHRs) offer best practice a...

journal_title：American journal of hypertension

authors： Swedlund M,Norton D,Birstler J,Chen G,Cruz L,Hanrahan L

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The collateral circulation is important in maintenance of blood supply to the ischemic kidney distal to renal artery stenosis (RAS). Obesity metabolic syndrome (MetS) preserves renal blood flow (RBF) in the stenotic kidney, but whether this is related to an increase of collateral vessel growth is unknown. We...

journal_title：American journal of hypertension

authors： Zhang X,Kim SR,Ferguson CM,Ebrahimi B,Hedayat AF,Lerman A,Lerman LO

更新日期：2018-11-13 00:00:00

abstract：BACKGROUND:In the United States, roughly one-third of adults have hypertension; another third have prehypertension. The prevalence of hypertension in deaf American Sign Language (ASL) users is unknown. We address this gap through a descriptive study for the prevalence of hypertension in the American Deaf community and ...

journal_title：American journal of hypertension

authors： Simons AN,Moreland CJ,Kushalnagar P

更新日期：2018-10-15 00:00:00

abstract：BACKGROUND:Considering sex differences, salt sensitivity, and insulin resistance (IR), the effect of sodium restriction and increased potassium intake on blood pressure remains unclear in normotensive Asian individuals, compared to that in hypertensive patients. METHODS:To assess the influence of sodium and potassium ...

journal_title：American journal of hypertension

authors： Murao S,Takata Y,Yasuda M,Osawa H,Kohi F

更新日期：2018-07-16 00:00:00

abstract：BACKGROUND:Guidelines recommend that patients with newly elevated office blood pressure undergo ambulatory blood pressure monitoring (ABPM) or home blood pressure monitoring (HBPM) to rule-out white coat hypertension before being diagnosed with hypertension. We explored patients' perspectives of the barriers and facili...

journal_title：American journal of hypertension

authors： Carter EJ,Moise N,Alcántara C,Sullivan AM,Kronish IM

更新日期：2018-07-16 00:00:00

abstract：BACKGROUND:Matrix Gla protein (MGP) is a vascular calcification inhibitor dependent upon vitamin K for activation. Evidence suggests that elevated plasma inactive MGP levels (desphospho-uncarboxylated MGP, dp-ucMGP; indicating poorer vascular vitamin K status) are associated with greater cardiovascular disease (CVD) ri...

journal_title：American journal of hypertension

authors： Fain ME,Kapuku GK,Paulson WD,Williams CF,Raed A,Dong Y,Knapen MHJ,Vermeer C,Pollock NK

更新日期：2018-05-07 00:00:00

abstract：BACKGROUND:A modest rise in blood pressure (BP) reportedly increases cardiovascular mortality despite not reaching obvious hypertension, suggesting that target organ damages are latently induced by slight BP rising. The goal of this study was to determine whether presence of subclinical myocardial damage can predict th...

journal_title：American journal of hypertension

authors： Honda Y,Watanabe T,Tamura H,Nishiyama S,Takahashi H,Arimoto T,Shishido T,Miyamoto T,Shibata Y,Konta T,Kayama T,Kubota I

更新日期：2018-04-13 00:00:00

abstract：BACKGROUND:Evaluating effect of acute or chronic use of antihypertensives on risk of falls in older adults. METHODS:Data sources: Systematic search of primary research articles in CINAHL, Cochrane, EBM, EMBASE, and MEDLINE databases from January 1 2007 to June 1 2017. Study selection: Research studies of cohort, case-...

journal_title：American journal of hypertension

authors： Kahlaee HR,Latt MD,Schneider CR

更新日期：2018-03-10 00:00:00

abstract：BACKGROUND:Salt sensitivity of blood pressure (SSBP) increases the risk of cardiovascular complications, and the heritability of SSBP is about 50% in Chinese population. However, studies identifying genes involved in BP responses to acute sodium loading and diuresis shrinkage are still limited. METHOD:A total of 342 e...

journal_title：American journal of hypertension

authors： Liu K,Liu Z,Qi H,Liu B,Wu J,Liu Y,Zhang J,Cao H,Yan Y,He Y,Zhang L

更新日期：2018-03-10 00:00:00

abstract：OBJECTIVES:Central blood pressure (BP) can be used to define hypertension. A central BP approach may be more sensitive than a conventional brachial BP approach in detecting hypertension. We aimed to compare the 2 approaches in estimating the prevalence hypertension in a nationally representative population. METHODS:A ...

journal_title：American journal of hypertension

authors： Chuang SY,Chang HY,Cheng HM,Pan WH,Chen CH

更新日期：2018-02-09 00:00:00