Association Between Chronic or Acute Use of Antihypertensive Class of Medications and Falls in Older Adults. A Systematic Review and Meta-Analysis.

abstract：:Blood pressure responses to 1 week of low (20 mmol sodium/day) and high (300 mmol sodium/day) salt intake were investigated in a double-blind, randomized study in 46 white, nonobese subjects with essential hypertension (13 women, 33 men; mean age 45.3 +/- 2.2 years, age range 25 to 80 years). The individuals were clas...

journal_title：American journal of hypertension

authors： Overlack A,Ruppert M,Kolloch R,Kraft K,Stumpe KO

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Hypertension is a definitive risk factor for stroke. We examined the associations between hypertension subtypes and stroke incidence in rural Chinese adults. METHODS:We conducted a prospective study in a sample of 38,949 rural Chinese adults aged ≥35 years and free from stroke at baseline. The subtypes of h...

journal_title：American journal of hypertension

authors： Sun Z,Han X,Zheng L,Zhang X,Li J,Hu D,Sun Y

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:There is conflicting information with regard to the effect of beta-blockers on arterial stiffness and wave reflection. We compared a vasodilating beta-blocker, nebivolol, with atenolol. METHODS:We randomized 40 subjects with untreated hypertension (mean +/- s.e.m. systolic/diastolic blood pressure (BP) of 1...

journal_title：American journal of hypertension

authors： Mahmud A,Feely J

更新日期：2008-06-01 00:00:00

abstract：:We sought to determine whether reductions in blood pressure in hypertensives after acute exercise persist for more than the 2 to 3 h found in controlled laboratory settings. Subjects (n = 11) were obese (32 +/- 4% body fat), sedentary (VO2max 27 +/- 4 mL/kg/min) 60 +/- 6-year-old men with stage 1 or 2 essential hypert...

journal_title：American journal of hypertension

authors： Taylor-Tolbert NS,Dengel DR,Brown MD,McCole SD,Pratley RE,Ferrell RE,Hagberg JM

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:There is an association between maternal body mass index (BMI) and preeclampsia, but if BMI has an effect on preeclampsia of all severities is debated. If there is an association between maternal height and preeclampsia of all severities is unknown. METHODS:In this population-based cohort study including 50...

journal_title：American journal of hypertension

authors： Sohlberg S,Stephansson O,Cnattingius S,Wikström AK

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Hypertension varies in prevalence among race/ethnic groups in the United States. Within-ethnic group differences associated with acculturation have been less frequently examined. We studied the association of three measures of acculturation (language spoken at home, place of birth, and years living in the US...

journal_title：American journal of hypertension

authors： Moran A,Diez Roux AV,Jackson SA,Kramer H,Manolio TA,Shrager S,Shea S

更新日期：2007-04-01 00:00:00

abstract：:The antidiabetic drug metformin lowers blood pressure (BP) more in spontaneously hypertensive rats (SHR) compared with Wistar-Kyoto rats (WKY), and the hypotensive effect is enhanced by high dietary salt. To determine whether enhanced hypotension is secondary to greater decreases in sympathetic nerve activity (SNA), w...

journal_title：American journal of hypertension

authors： Muntzel MS,Nyeduala B,Barrett S

更新日期：1999-12-01 00:00:00

abstract：:High levels of plasma homocyst(e)ine (H[e]) are associated with increased vascular risk. Treatment is being contemplated, but the level at which patients should be treated is not known. We compared the response of carotid plaque to vitamin therapy in patients with H(e) above and below 14 micromol/L, a level commonly r...

journal_title：American journal of hypertension

authors： Hackam DG,Peterson JC,Spence JD

更新日期：2000-01-01 00:00:00

abstract：:The objective of this study was to test the relationship between neurologic and microvascular complications of type 1 diabetes mellitus. It was hypothesized that the mechanisms operative in autonomic dysfunction seen in diabetic patients with microangiopathy play a role in the rapidity of progression to renal failure....

journal_title：American journal of hypertension

authors： Weinrauch LA,Kennedy FP,Gleason RE,Keough J,D'Elia JA

更新日期：1998-03-01 00:00:00

abstract：:The efficacy and safety of doxazosin (DOX) for the treatment of hypertension was investigated. A multicenter, double-blind, placebo-controlled, parallel design was employed. A 4-week placebo runin period was followed by a 9-week double-blind period during which patients were randomly assigned to placebo or 2, 4, or 8 ...

journal_title：American journal of hypertension

authors： Cubeddu LX,Pool JL,Bloomfield R,Klotman PE,Pickering BI,Wombolt DG,Nelson EB,Halperin A

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Whether left ventricular (LV) geometric remodeling, as indexed by relative wall thickness (RWT), aggregates in families and is inherited independent of LV mass (LVM) and additional confounders is uncertain. METHODS:We determined whether RWT as assessed from 2D targeted M-mode echocardiography shows intrafam...

journal_title：American journal of hypertension

authors： Peterson VR,Norton GR,Redelinghuys M,Libhaber CD,Maseko MJ,Majane OH,Brooksbank R,Woodiwiss AJ

更新日期：2015-05-01 00:00:00

abstract：:Twenty-four hour blood pressure exposure and circadian blood pressure variability may be important predictors of hypertensive end-organ damage. Since sleep is a major determinant of circadian blood pressure decline, day/night blood pressure changes may be affected by sleep intervals. The current study compares 24-h bl...

journal_title：American journal of hypertension

authors： Rosansky SJ,Menachery SJ,Wagner CM,Jackson K

更新日期：1995-07-01 00:00:00

abstract：:This study was undertaken to examine whether prostaglandin (PG) inhibition with indomethacin interferes with angiotensin II receptor blockade (losartan) during treatment for arterial hypertension. In a double-blind crossover design 10 patients with essential arterial hypertension and treated with losartan were randomi...

journal_title：American journal of hypertension

authors： Olsen ME,Thomsen T,Hassager C,Ibsen H,Dige-Petersen H

更新日期：1999-02-01 00:00:00

abstract：:Endothelin-1 is a potent vasoconstrictor peptide produced in blood vessels and other tissues that may play an important role in the control of local blood flow and could be involved in the pathogenesis of hypertension. Our previous studies have documented increases in endothelin-1 peptide content and gene expression i...

journal_title：American journal of hypertension

authors： Day R,Larivière R,Schiffrin EL

更新日期：1995-03-01 00:00:00

abstract：:To evaluate the existence of a relationship between atrial natriuretic factor (ANF) and plasma Na+/K+ATPase inhibitory activity in humans, we examined the hemodynamic and humoral response to volume expansion in 41 borderline hypertensive patients (BHT) with either normal (n = 33) or low plasma renin activity (n = 8). ...

journal_title：American journal of hypertension

authors： Borghi C,Boschi S,Costa FV,Ambrosioni E

更新日期：1991-07-01 00:00:00

abstract：:The objective of this study was to evaluate whether the major histocompatibility complex of the rat can be related to blood pressure (BP) level and BP response to stress. Blood pressure was determined under light ether anesthesia or during moderate restraint stress in normotensive Lewis rats, in rat strains congenic w...

journal_title：American journal of hypertension

authors： Kunes J,Kohoutová M,Zicha J

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:The aim was to determine the proportions and correlates of essential hypertension among children in a tertiary pediatric hypertension clinic. METHODS:We evaluated 423 consecutive children and collected demographic and clinical history by retrospective chart review. RESULTS:We identified 275 (65%) hypertens...

journal_title：American journal of hypertension

authors： Gupta-Malhotra M,Banker A,Shete S,Hashmi SS,Tyson JE,Barratt MS,Hecht JT,Milewicz DM,Boerwinkle E

更新日期：2015-01-01 00:00:00

abstract：:Surveys taken of blood pressure in Greenland indicated prevailing levels similar to those in the USA. Morphometrically measured renovasculopathies in 88 autopsies confirmed blood pressure levels comparable to the survey findings. At clinic visits, the recorded blood pressures in 48 of the autopsies verified the morpho...

journal_title：American journal of hypertension

authors： Tracy RE,Mulvad G,Pederson HS,Jul E,Bjerregaard P,Newman WP 3rd

更新日期：1996-06-01 00:00:00

abstract：:The polymorphism of the angiotensin-converting enzyme gene is considered to be associated with increased risk for stroke, but there is a diversity in the results obtained. The genetic involvement of the renin-angiotensin system in stroke also remains unclear. To predict the genetic risk of lacunar infarction, we condu...

journal_title：American journal of hypertension

authors： Takami S,Imai Y,Katsuya T,Ohkubo T,Tsuji I,Nagai K,Satoh H,Hisamichi S,Higaki J,Ogihara T

更新日期：2000-02-01 00:00:00

abstract：:The results of our previous studies suggested that endothelin-1 (ET-1) might be contributory to the impaired uteroplacental blood flow seen in preeclampsia. The aim of this study was to investigate the in vitro influence of isradipine on ET-1-induced contraction of myometrial resistance arteries from pregnant women, a...

journal_title：American journal of hypertension

authors： Kublickiene KR,Wolff K,Kublickas M,Lindblom B,Lunell NO,Nisell H

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:African-American men have stiffer arteries than white men at rest. We sought to test the hypothesis that reductions in stiffness after aerobic exercise may be attenuated in African-American (AA) men compared with white (W) men. METHODS:Twenty-four young men (age 22+/-1.0 years; 12 AA and 12 W) underwent mea...

journal_title：American journal of hypertension

authors： Heffernan KS,Jae SY,Fernhall B

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:The adipose tissue renin-angiotensin system (RAS) has been implicated in the pathophysiology of obesity and dysfunction of adipose tissue. However, neither regulation of angiotensinogen (AGT) expression in adipose tissue nor secretion of adipose tissue-derived AGT has been fully elucidated in humans. METHOD...

journal_title：American journal of hypertension

authors： Yasue S,Masuzaki H,Okada S,Ishii T,Kozuka C,Tanaka T,Fujikura J,Ebihara K,Hosoda K,Katsurada A,Ohashi N,Urushihara M,Kobori H,Morimoto N,Kawazoe T,Naitoh M,Okada M,Sakaue H,Suzuki S,Nakao K

更新日期：2010-04-01 00:00:00

abstract：:Plasma plasminogen activator inhibitor type 1 (PAI-1) and tissue plasminogen activator (tPA) antigens and activities were measured in 28 patients with hypertension and 12 normal controls. Steady state plasma glucose (SSPG) concentrations were also determined after an infusion of somatostatin, insulin and glucose. Pati...

journal_title：American journal of hypertension

authors： Jeng JR,Sheu WH,Jeng CY,Huang SH,Shieh SM

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Liddle's syndrome (LS) is a monogenic form of hypertension simulating a mineralocorticoid excess, and is currently suspected in young hypokalemic hypertensives. The aims of the study were: (i) to evaluate the clinical phenotype of LS in a newly identified Italian family of Sicilian origin carrying a gain-of-...

journal_title：American journal of hypertension

authors： Rossi E,Farnetti E,Nicoli D,Sazzini M,Perazzoli F,Regolisti G,Grasselli C,Santi R,Negro A,Mazzeo V,Mantero F,Luiselli D,Casali B

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Recent studies have revealed the existence of bone marrow-derived endothelial progenitor cells (EPCs). The number of circulating EPCs might reflect the pathogenesis of atherosclerosis and progression of cardiovascular diseases (CVDs). The purpose of this study was to evaluate the relationship between the num...

journal_title：American journal of hypertension

authors： Umemura T,Soga J,Hidaka T,Takemoto H,Nakamura S,Jitsuiki D,Nishioka K,Goto C,Teragawa H,Yoshizumi M,Chayama K,Higashi Y

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Currently, total hyperhomocysteinemia (tHHcy) is a well-known condition linked to a higher risk of vascular disease. Prevalence of HHcy increases in elderly persons as the risk associated with it persists. Because factors can be potentially reduced in the elderly, it is important to carry out epidemiologic s...

journal_title：American journal of hypertension

authors： Janson JJ,Galarza CR,Murúa A,Quintana I,Przygoda PA,Waisman G,Camera L,Kordich L,Morales M,Mayorga LM,Camera MI

更新日期：2002-05-01 00:00:00

abstract：:We compared three drugs representing different classes of antidiabetic pharmacology (glyburide, a sulfonylurea; pioglitazone, a thiazolidinedione; and metformin, a biguanide) in terms of their direct effects on proliferation of cultured arterial smooth muscle cells (SMC). Rat aortic SMC were seeded at 4 x 10(4)/35 mm ...

journal_title：American journal of hypertension

authors： Peuler JD,Phare SM,Iannucci AR,Hodorek MJ

更新日期：1996-02-01 00:00:00

abstract：:To clarify the function of polymorphonuclear leukocytes (PMN) in spontaneously hypertensive rats (SHR) and the effect of beraprost sodium (BS) on these functions, we examined superoxide anion (O2-) production and adherent activity by PMN, as well as modification of these functions by BS ex vivo and in vitro. In study ...

journal_title：American journal of hypertension

authors： Ohmori M,Kitoh Y,Kawaguchi A,Harada K,Sugimoto K,Fujimura A

更新日期：2001-07-01 00:00:00

abstract：:The metabolic syndrome is a cluster of disturbances such as type 2 diabetes mellitus, hypertension, central obesity, dyslipidemia, and others for which insulin resistance and compensatory hyperinsulinemia have been proposed to be the underlying disorders. Several possible mechanisms linking insulin resistance and comp...

journal_title：American journal of hypertension

authors： Sarafidis PA,Lasaridis AN

更新日期：2006-06-01 00:00:00

abstract：:Increased adrenergic activity has been suggested to mediate the hypertension associated with hyperinsulinemia. This study tested whether combined alpha1- and beta-adrenergic receptor blockade would prevent insulin-induced hypertension when euglycemia was maintained by continuous intravenous glucose infusion. Sprague-D...

journal_title：American journal of hypertension

authors： Keen HL,Brands MW,Alonso-Galicia M,Hall JE

更新日期：1996-12-01 00:00:00