当前位置： SCI文献检索 > AMERICAN JOURNAL OF HYPERTENSION期刊下所有文献 > Essential hypertension vs. secondary hypertension among children.

Essential hypertension vs. secondary hypertension among children.

Abstract：

BACKGROUND:The aim was to determine the proportions and correlates of essential hypertension among children in a tertiary pediatric hypertension clinic. METHODS:We evaluated 423 consecutive children and collected demographic and clinical history by retrospective chart review. RESULTS:We identified 275 (65%) hypertensive children (blood pressure >95th percentile per the "Fourth Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents") from 423 children referred to the clinic for history of elevated blood pressure. The remainder of the patients had normotension (11%), white coat hypertension (11%), prehypertension (10%), and pending diagnosis (3%). Among the 275 hypertensive children, 43% (n = 119; boys = 56%; median age = 12 years; range = 3-17 years) had essential hypertension and 57% (n = 156; boys = 66%; median age = 9 years; range = 0.08-19 years) had secondary hypertension. When compared with those with secondary hypertension, those with essential hypertension had a significantly older age at diagnosis (P = 0.0002), stronger family history of hypertension (94% vs. 68%; P < 0.0001), and lower prevalence of preterm birth (20% vs. 46%; P < 0.001). There was a bimodal distribution of age of diagnosis in those with secondary hypertension. CONCLUSIONS:The phenotype of essential hypertension can present as early as 3 years of age and is the predominant form of hypertension in children after age of 6 years. Among children with hypertension, those with essential hypertension present at an older age, have a stronger family history of hypertension, and have lower prevalence of preterm birth.

journal_name

Am J Hypertens

journal_title

American journal of hypertension

authors

Gupta-Malhotra M,Banker A,Shete S,Hashmi SS,Tyson JE,Barratt MS,Hecht JT,Milewicz DM,Boerwinkle E

doi

10.1093/ajh/hpu083

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

73-80

issue

1

eissn

0895-7061

issn

1941-7225

pii

hpu083

journal_volume

28

pub_type

杂志文章

相关文献

AMERICAN JOURNAL OF HYPERTENSION文献大全
  • Inactive Matrix Gla Protein, Arterial Stiffness, and Endothelial Function in African American Hemodialysis Patients.

    abstract：BACKGROUND:Matrix Gla protein (MGP) is a vascular calcification inhibitor dependent upon vitamin K for activation. Evidence suggests that elevated plasma inactive MGP levels (desphospho-uncarboxylated MGP, dp-ucMGP; indicating poorer vascular vitamin K status) are associated with greater cardiovascular disease (CVD) ri...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpy049

    authors： Fain ME,Kapuku GK,Paulson WD,Williams CF,Raed A,Dong Y,Knapen MHJ,Vermeer C,Pollock NK

    更新日期：2018-05-07 00:00:00

  • Azilsartan improves glycemic status and reduces kidney damage in zucker diabetic fatty rats.

    abstract：BACKGROUND:Azilsartan medoxomil (AZL-M), an angiotensin II receptor blocker, demonstrates antihypertensive and organ protective effects in hypertension. We investigated the efficacy of AZL-M to ameliorate metabolic syndrome and kidney damage associated with type 2 diabetes using Zucker diabetic fatty (ZDF) rats. METHO...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpu016

    authors： Hye Khan MA,Neckář J,Haines J,Imig JD

    更新日期：2014-08-01 00:00:00

  • Etiology and pathophysiology of stroke as a complex trait.

    abstract：:Stroke (brain attack) is currently the third leading cause of death in Western societies. Recent advances in molecular genetics have finally demonstrated what has long been suggested by the clinical observation, that is, stroke is not only the complication of major pathologic conditions such as atherosclerosis, hypert...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,评审

    doi：10.1016/s0895-7061(00)01249-8

    authors： Rubattu S,Giliberti R,Volpe M

    更新日期：2000-10-01 00:00:00

  • Intracerebroventricular metformin attenuates salt-induced hypertension in spontaneously hypertensive rats.

    abstract：:The aim of this study was to examine the effects of long-term continuous intracerebroventricular (icv) infusion of metformin on blood pressure (BP) in spontaneously hypertensive rats (SHR). To accelerate the development of hypertension, SHR were fed a 8% NaCl diet during the 3-week study period. Metformin was given in...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(01)02220-8

    authors： Petersen JS,Andersen D,Muntzel MS,Diemer NH,Holstein-Rathlou NH

    更新日期：2001-11-01 00:00:00

  • B-type natriuretic Peptide is associated with both augmentation index and left ventricular mass in diabetic patients without heart failure.

    abstract：BACKGROUND:B-type natriuretic peptide (BNP) increases the risk of death and cardiovascular events in patients without heart failure, even at BNP values within the "normal" range. The reasons for this are unclear. METHODS:We performed two separate studies (n = 33 and n = 129) on subjects with type 2 diabetes mellitus i...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/j.amjhyper.2005.06.016

    authors： Dawson A,Davies JI,Morris AD,Struthers AD

    更新日期：2005-12-01 00:00:00

  • Acculturation is associated with hypertension in a multiethnic sample.

    abstract：BACKGROUND:Hypertension varies in prevalence among race/ethnic groups in the United States. Within-ethnic group differences associated with acculturation have been less frequently examined. We studied the association of three measures of acculturation (language spoken at home, place of birth, and years living in the US...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/j.amjhyper.2006.09.025

    authors： Moran A,Diez Roux AV,Jackson SA,Kramer H,Manolio TA,Shrager S,Shea S

    更新日期：2007-04-01 00:00:00

  • Relationship between nutrition and blood pressure: a cross-sectional analysis from the NutriNet-Santé Study, a French web-based cohort study.

    abstract：BACKGROUND:Hypertension is the most prevalent chronic disease worldwide. Lifestyle behaviors for its prevention and control are recommended within worldwide guidelines. Nevertheless, their combined relationship with blood pressure (BP) level, particularly in the general population, would need more investigations. Our a...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpu164

    authors： Lelong H,Galan P,Kesse-Guyot E,Fezeu L,Hercberg S,Blacher J

    更新日期：2015-03-01 00:00:00

  • Reversible posterior leukoencephalopathy secondary to indinavir-induced hypertensive crisis: a case report.

    abstract：:Reversible posterior leukoencephalopathy syndrome (RPLS) is an uncommon entity related to multiple and different pathologies, the most common being hypertensive crisis. It is believed to be secondary to the breakdown on the blood-brain barrier. At the beginning, it is undistinguishable from other leukoencephalopathies...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(02)02264-1

    authors： Giner V,Fernández C,Esteban MJ,Galindo MJ,Forner MJ,Guix J,Redón J

    更新日期：2002-05-01 00:00:00

  • Social and economic factors as obstacles to blood pressure control.

    abstract：:Further improvement in blood pressure control at the population level will result from dealing with hard-to-solve problems, such as access to care, long-term management of a chronic disease, and societal influences on lifestyle. Additional knowledge and experimental data are needed, reinforced by clear public health c...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(98)00082-x

    authors： Lang T

    更新日期：1998-07-01 00:00:00

  • Sexual activity and plasma testosterone levels in hypertensive males.

    abstract：:The aim of this study was to compare sexual activity and plasma testosterone levels of hypertensive men with those of healthy normotensive controls. We investigated 110 newly diagnosed, never treated hypertensive (blood pressure [BP] > or = 140/95 mm Hg) men and 110 healthy normotensive (diastolic BP <90 mm Hg) men. A...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(01)02280-4

    authors： Fogari R,Zoppi A,Preti P,Rinaldi A,Marasi G,Vanasia A,Mugellini A

    更新日期：2002-03-01 00:00:00

  • I1 receptors, cardiovascular function, and metabolism.

    abstract：:When injected into the medullary site of the hypotensive action of clonidine, imidazolines and related compounds decrease blood pressure (BP), whereas no phenylethylamine compounds were capable of producing such an effect at the same site. There is much biochemical and pharmacologic evidence to support the involvement...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,评审

    doi：10.1016/s0895-7061(01)02238-5

    authors： Bousquet P

    更新日期：2001-11-01 00:00:00

  • Gender differences in insulin-stimulated glucose utilization among African-Americans.

    abstract：:The purpose of this study was to determine whether there are gender differences in plasma insulin levels or insulin resistance in young adult African-Americans. Male (n = 53) and female (n = 45) subjects (age 23 to 28 years) included normotensives (N, blood pressure [BP] < 135/85 mm Hg) and borderline hypertensives (B...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/7.11.948

    authors： Falkner B,Hulman S,Kushner H

    更新日期：1994-11-01 00:00:00

  • Association of Orthostatic Hypotension Timing With Clinical Events in Adults With Diabetes and Hypertension: Results From the ACCORD Trial.

    abstract：OBJECTIVE:To determine the effects of orthostatic hypotension (OH) measurement timing on its associations with dizziness, falls, fractures, cardiovascular disease (CVD), and mortality. METHODS:We analyzed OH measurements from the Action to Control Cardiovascular Risk in Diabetes BP trial, which evaluated two blood pre...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpz015

    authors： Juraschek SP,Lipsitz LA,Beach JL,Mukamal KJ

    更新日期：2019-06-11 00:00:00

  • Active vitamin D and accelerated progression of aortic stiffness in hemodialysis patients: a longitudinal observational study.

    abstract：BACKGROUND:We hypothesized that high-dose active vitamin D therapy in the form of alphacalcidol (α-calcidol), used to treat secondary hyperparathyroidism in chronic kidney disease, could lead to vascular calcification and accelerated progression of aortic stiffness. METHODS:We conducted an observational study in 85 pa...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpu057

    authors： Fortier C,Mac-Way F,De Serres SA,Marquis K,Douville P,Desmeules S,Larivière R,Agharazii M

    更新日期：2014-11-01 00:00:00

  • Improved cardiovascular risk stratification by a simple ECG index in hypertension.

    abstract：BACKGROUND:We determined the prognostic value of the Cornell/strain [C/S] index, a simple electrocardiographic (ECG) index for left ventricular hypertrophy (LVH) defined by the presence of either a classic strain pattern or a Cornell voltage (sum of R in aVL + S in V(3)) >2.0 mV in women or 2.4 mV in men, or both. MET...

    journal_title：American journal of hypertension

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0895-7061(03)00912-9

    authors： Verdecchia P,Angeli F,Reboldi G,Carluccio E,Benemio G,Gattobigio R,Borgioni C,Bentivoglio M,Porcellati C,Ambrosio G

    更新日期：2003-08-01 00:00:00

  • Beta-blockers reduce aortic stiffness in hypertension but nebivolol, not atenolol, reduces wave reflection.

    abstract：BACKGROUND:There is conflicting information with regard to the effect of beta-blockers on arterial stiffness and wave reflection. We compared a vasodilating beta-blocker, nebivolol, with atenolol. METHODS:We randomized 40 subjects with untreated hypertension (mean +/- s.e.m. systolic/diastolic blood pressure (BP) of 1...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,随机对照试验

    doi：10.1038/ajh.2008.156

    authors： Mahmud A,Feely J

    更新日期：2008-06-01 00:00:00

  • Plasma pentraxin3 and arterial stiffness in men with obstructive sleep apnea.

    abstract：BACKGROUND:Obstructive sleep apnea (OSA) induces inflammation and vascular damage that might contribute to an increased risk of cardiovascular disease (CVD). However, the mechanisms linking OSA and CVD are not fully understood. Pentraxin3 may play a significant role in vascular inflammation and damage. Currently, there...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1038/ajh.2010.248

    authors： Kasai T,Inoue K,Kumagai T,Kato M,Kawana F,Sagara M,Ishiwata S,Ohno M,Yamaguchi T,Momomura S,Narui K

    更新日期：2011-04-01 00:00:00

  • Ostial renal artery stent placement in patients 75 years of age or older.

    abstract：:Renal artery stent placement has been shown to improve blood pressure (BP) and stabilize renal function in patients with atherosclerotic renovascular disease. However, limited data are available in patients > or = 75 years of age. We analyzed the prestent characteristics and clinical outcomes of patients aged > or = 7...

    journal_title：American journal of hypertension

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0895-7061(01)02168-9

    authors： Bloch MJ,Trost DA,Whitmer J,Pickering TG,Sos TA,August P

    更新日期：2001-10-01 00:00:00

  • Associations of Reservoir-Excess Pressure Parameters Derived From Central and Peripheral Arteries With Kidney Function.

    abstract：BACKGROUND:Central artery reservoir-excess pressure parameters are clinically important but impractical to record directly. However, diastolic waveform morphology is consistent across central and peripheral arteries. Therefore, peripheral artery reservoir-excess pressure parameters related to diastolic waveform morphol...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpaa013

    authors： Armstrong MK,Schultz MG,Picone DS,Black JA,Dwyer N,Roberts-Thomson P,Sharman JE

    更新日期：2020-04-01 00:00:00

  • Association of increased erythrocyte Na+/H+ exchanger with renal Na+ retention in patients with essential hypertension.

    abstract：:The goal of this study was to investigate the activity of the Na+/H+ exchanger in erythrocytes of patients with essential hypertension and its relation with urinary Na+ excretion. The study was performed in cells from 27 untreated hypertensive patients and 30 normotensive controls with similar age and sex distribution...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/0895-7061(94)00172-8

    authors： Díez J,Alonso A,Garciandía A,López R,Gómez-Alamillo C,Arrázola A,Fortuño A

    更新日期：1995-02-01 00:00:00

  • Comparative Cost-Effectiveness of Hypertension Treatment in Non-Hispanic Blacks and Whites According to 2014 Guidelines: A Modeling Study.

    abstract：BACKGROUND:We compared the cost-effectiveness of hypertension treatment in non-Hispanic blacks and non-Hispanic whites according to 2014 US hypertension treatment guidelines. METHODS:The cardiovascular disease (CVD) policy model simulated CVD events, quality-adjusted life years (QALYs), and treatment costs in 35- to 7...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpw047

    authors： Vasudeva E,Moise N,Huang C,Mason A,Penko J,Goldman L,Coxson PG,Bibbins-Domingo K,Moran AE

    更新日期：2016-10-01 00:00:00

  • Interactions between dietary calcium and caffeine consumption on calcium metabolism in hypertensive humans.

    abstract：:Abnormal calcium metabolism has been implicated in human hypertension. Caffeine consumption may contribute to hypertension since it increases urinary calcium excretion. Nineteen hypertensive subjects (HTN) and nineteen age and gender matched normotensive controls (NTC) who habitually consumed at least 175 mg caffeine ...

    journal_title：American journal of hypertension

    pub_type： 临床试验,杂志文章

    doi：10.1016/0895-7061(95)00337-1

    authors： Wise KJ,Bergman EA,Sherrard DJ,Massey LK

    更新日期：1996-03-01 00:00:00

  • Factors Associated With Treatment and Control of Hypertension in a Healthy Elderly Population Free of Cardiovascular Disease: A Cross-sectional Study.

    abstract：BACKGROUND:Despite readily available treatments, control of blood pressure (BP) with population aging remains suboptimal. Further, there are gaps in the understanding of the management of high BP in the aged. We explored antihypertensive treatment and control among elderly hypertensive participants free from overt card...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,多中心研究

    doi：10.1093/ajh/hpz192

    authors： Chowdhury EK,Nelson MR,Ernst ME,Margolis KL,Beilin LJ,Johnston CI,Woods RL,Murray AM,Wolfe R,Storey E,Shah RC,Lockery JE,Tonkin AM,Newman AB,Williamson JD,Abhayaratna WP,Stocks NP,Fitzgerald SM,Orchard SG,Trevaks RE

    更新日期：2020-04-01 00:00:00

  • Asymmetric dimethylarginine (ADMA) has a role in regulating systemic vascular tone in young healthy subjects: the cardiovascular risk in young Finns study.

    abstract：BACKGROUND:This study was designed to evaluate whether plasma asymmetric dimethylarginine (ADMA) has any role in predicting hemodynamic responses in clinically healthy young subjects. ADMA, as an endogenous nitric oxide (NO) synthase inhibitor, has been demonstrated to associate with hypertension and vascular reactivit...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1038/ajh.2008.215

    authors： Päivä H,Kähönen M,Lehtimäki T,Raitakari OT,Jula A,Viikari J,Alfthan G,Juonala M,Laaksonen R,Hutri-Kähönen N

    更新日期：2008-08-01 00:00:00

  • Relationship Between Dynamic Changes in Body Weight and Blood Pressure: The ESTEBAN Survey.

    abstract：BACKGROUND:Obesity is one of the main determinants of blood pressure. The aim of this study was to evaluate and quantify the relations between the different anthropometric indices and blood pressure (BP) stratified by gender. METHODS:Cross-sectional analyses were performed using data from 2,105 adults from the ESTEBAN...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpz096

    authors： Vallée A,Perrine AL,Deschamps V,Blacher J,Olié V

    更新日期：2019-09-24 00:00:00

  • Erythrocyte Na-K-Cl cotransport activity in low renin essential hypertensive patients. A 23Na nuclear magnetic resonance study.

    abstract：:The Na-K-Cl cotransport activity in red blood cells from essential hypertensive men with low (n = 8, mean age 42 +/- 4 years) or normal renin activity (n = 4, mean age 43 +/- 3 years), and in normotensive men with normal renin activity (n = 7, mean age 38 +/- 4 years) has been evaluated by means of a recently develope...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/7.2.151

    authors： Cacciafesta M,Ferri C,Carlomagno A,De Angelis C,Scuteri A,Guidoni L,Luciani AM,Rosi A,Viti V,Santucci A

    更新日期：1994-02-01 00:00:00

  • Blood pressure and cognitive functioning among independent elderly.

    abstract：BACKGROUND:The morbidity and mortality benefits of blood pressure (BP) control for the elderly is well documented. The cognitive consequences of hypertension control in this population, however, are still under debate. We aim to study the association between BP and cognitive performance in the elderly. Specifically, we...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(03)01005-7

    authors： Paran E,Anson O,Reuveni H

    更新日期：2003-10-01 00:00:00

  • Albumin excretion rate and metabolic modifications in patients with essential hypertension. Effects of two angiotensin converting enzyme inhibitors.

    abstract：:A prospective randomized, double-blind, double-dummy study investigated the effects of two angiotensin converting enzyme (ACE) inhibitors on urinary albumin excretion in nondiabetic patients with mild to moderate essential hypertension. At the end of a 4-week placebo run-in period, 36 patients were randomly allocated ...

    journal_title：American journal of hypertension

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1093/ajh/7.1.46

    authors： Puig JG,Mateos FA,Ramos TH,Lavilla MP,Capitán MC,Gil A

    更新日期：1994-01-01 00:00:00

  • Angiotensin II upregulates transforming growth factor-beta type I receptor on rat vascular smooth muscle cells.

    abstract：:Angiotensin II (Ang II) and transforming growth factor-beta (TGF-beta) modulate cell growth and metabolism. Our objective was to evaluate the effect of Ang II on the characteristics and expression of TGF-beta receptors on vascular smooth muscle cells (VSMC) from Wistar-Kyoto rats. The addition of TGF-beta1 elicited a ...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(99)00152-1

    authors： Fukuda N,Hu WY,Kubo A,Kishioka H,Satoh C,Soma M,Izumi Y,Kanmatsuse K

    更新日期：2000-02-01 00:00:00

  • Effect of ACE inhibition on pressor, renal vascular, and adrenal responses to infusion of angiotensin I in normal subjects eating a low-salt diet.

    abstract：:To examine the influence of angiotensin-converting enzyme (ACE) on pressor, renal vascular, and adrenal responses during angiotensin I (Ang I) infusion, we studied 10 normotensive, healthy men. Each was in balance with a 10-mEq sodium, 100-mEq potassium intake and was studied before and during ACE inhibition with enal...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(99)00223-x

    authors： Hollenberg NK,Fisher ND,Price DA,Williams GH

    更新日期：2000-05-01 00:00:00