Actions of peroxisome proliferator-activated receptors-gamma agonists explaining a possible blood pressure-lowering effect.

abstract：:Twenty-four hour blood pressure exposure and circadian blood pressure variability may be important predictors of hypertensive end-organ damage. Since sleep is a major determinant of circadian blood pressure decline, day/night blood pressure changes may be affected by sleep intervals. The current study compares 24-h bl...

journal_title：American journal of hypertension

authors： Rosansky SJ,Menachery SJ,Wagner CM,Jackson K

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:It is known that essential hypertension may be implicated in the development of cognitive impairment that is associated to microvascular disease of the brain. It has been hypothesized that increased arterial stiffness of the large arteries may lead to microvascular changes due to increased pulsatile flow. Ou...

journal_title：American journal of hypertension

authors： Triantafyllidi H,Arvaniti C,Lekakis J,Ikonomidis I,Siafakas N,Tzortzis S,Trivilou P,Zerva L,Stamboulis E,Kremastinos DT

更新日期：2009-05-01 00:00:00

abstract：:Kidney stones affect hypertensive patients disproportionately compared to normotensive individuals. On the other hand, some prospective data suggest that a history of nephrolithiasis was associated with a greater tendency to develop hypertension. Newer epidemiologic data also link obesity and diabetes, features of the...

journal_title：American journal of hypertension

authors： Obligado SH,Goldfarb DS

更新日期：2008-03-01 00:00:00

abstract：:To evaluate the clinical importance of serum hepatocyte growth factor (HGF) concentration, we designed two clinical investigations. The first study analyzed the correlation between serum HGF concentration and clinical arterial stiffness or the vasodilator response to reactive hyperemia in hypertensive patients. The se...

journal_title：American journal of hypertension

authors： Komai N,Ohishi M,Morishita R,Moriguchi A,Kaibe M,Matsumoto K,Rakugi H,Higaki J,Ogihara T

更新日期：2002-06-01 00:00:00

abstract：:Essential hypertension conveys an increased risk of cardiovascular morbidity and mortality. The common finding of an autonomic imbalance in these patients contributes not only to the etiology of hypertension itself, but also to the cardiac risk and resulting adverse sequelae. A high sympathetic tone in particular is r...

journal_title：American journal of hypertension

authors： Brook RD,Julius S

更新日期：2000-06-01 00:00:00

abstract：:The aim of this study was to examine the effects of long-term continuous intracerebroventricular (icv) infusion of metformin on blood pressure (BP) in spontaneously hypertensive rats (SHR). To accelerate the development of hypertension, SHR were fed a 8% NaCl diet during the 3-week study period. Metformin was given in...

journal_title：American journal of hypertension

authors： Petersen JS,Andersen D,Muntzel MS,Diemer NH,Holstein-Rathlou NH

更新日期：2001-11-01 00:00:00

abstract：:Most ambulatory blood pressure monitoring (ABPM) studies have used a mechanical clock as the reference time, but there is no biologic background for assuming that midnight by the mechanical clock is zero hour by the biologic clock. The aim of this study was to determine the biologic zero hour as the zero reference tim...

journal_title：American journal of hypertension

authors： Okutani M,Komori S,Iwasaki H,Mochizuki Y,Kohno I,Mochizuki S,Ishii H,Ijiri H,Tamura K

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:On the basis of evidence of plasma leptin (LE) effects on cardiovascular system, we assessed possible association of LE and Doppler-derived left ventricular (LV) diastolic function in arterial hypertension. METHODS:Doppler echocardiography, blood sample for fasting plasma LE levels, and euglycemic hyperinsu...

journal_title：American journal of hypertension

authors： Galderisi M,Tagliamonte MR,D'Errico A,Carella C,Varricchio G,Mondillo S,de Divitiis O,Paolisso G

更新日期：2001-10-01 00:00:00

abstract：:The insulin sensitivity of five essential hypertensive patients was compared to five patients with renovascular hypertension, five patients with primary hyperaldosteronism, and five normotensive subjects, using the euglycemic hyperinsulinemic clamp technique. Essential hypertensive patients had significantly lower ins...

journal_title：American journal of hypertension

authors： Shamiss A,Carroll J,Rosenthal T

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:We previously showed that the infusion of tumor necrosis factor alpha (TNF-alpha) induces hypertension and vascular dysfunction in late pregnant but not virgin rats. In the present study, we tested the hypothesis that levels of ovarian hormones to mimic pregnancy are required for TNF-alpha-induced changes in...

journal_title：American journal of hypertension

authors： LaMarca BD,Chandler DL,Grubbs L,Bain J,McLemore GR Jr,Granger JP,Ryan MJ

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Salt sensitivity of blood pressure (SSBP) increases the risk of cardiovascular complications, and the heritability of SSBP is about 50% in Chinese population. However, studies identifying genes involved in BP responses to acute sodium loading and diuresis shrinkage are still limited. METHOD:A total of 342 e...

journal_title：American journal of hypertension

authors： Liu K,Liu Z,Qi H,Liu B,Wu J,Liu Y,Zhang J,Cao H,Yan Y,He Y,Zhang L

更新日期：2018-03-10 00:00:00

abstract：BACKGROUND:Cardiovascular diseases (CVD) are responsible for more than 50% of the deaths in patients with end-stage renal disease (ESRD). Sleep apnea (SA) has been recognized as a risk factor for CVD. Previous studies have shown a higher prevalence of SA among patients on dialysis. METHODS:Forty-five nondiabetics pati...

journal_title：American journal of hypertension

authors： de Oliveira Rodrigues CJ,Marson O,Tufic S,Kohlmann O Jr,Guimarães SM,Togeiro P,Ribeiro AB,Tavares A

更新日期：2005-02-01 00:00:00

abstract：:The comparative efficacy of the calcium antagonists isradipine and nifedipine in reducing left ventricular peak systolic wall tension was assessed in 25 patients with essential hypertension (20 men, 5 women; mean age: 49 years). After 2 weeks of treatment with either isradipine (2.5 mg twice daily) or slow-release nif...

journal_title：American journal of hypertension

authors： Griebenow R,Müller R,Steffen HM,Burger KJ,Welzel D

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:This study analyzed whether hypertension induced by N(omega)-nitro-l-arginine methyl ester (L-NAME) is associated with dysregulation of the main antioxidant enzymes (superoxide dismutase [SOD], catalase, glutathione peroxidase [GPX], and glutathione reductase [GR]) and whether chronic administration of tempo...

journal_title：American journal of hypertension

authors： Sainz J,Wangensteen R,Rodríguez Gómez I,Moreno JM,Chamorro V,Osuna A,Bueno P,Vargas F

更新日期：2005-06-01 00:00:00

abstract：:Understanding the causes and treatment of chronic hypotension is of benefit to affected patients and may also shed light on the physiology and genetics of mechanisms of blood pressure control. Symptomatic hypotension (almost always with a blood pressure fall greater than or equal to 20/10 mm Hg) may reflect unrecogniz...

journal_title：American journal of hypertension

authors： Robertson D,Mosqueda-Garcia R,Robertson RM,Biaggioni I

更新日期：1992-06-01 00:00:00

abstract：:Blood pressure responses to 1 week of low (20 mmol sodium/day) and high (300 mmol sodium/day) salt intake were investigated in a double-blind, randomized study in 46 white, nonobese subjects with essential hypertension (13 women, 33 men; mean age 45.3 +/- 2.2 years, age range 25 to 80 years). The individuals were clas...

journal_title：American journal of hypertension

authors： Overlack A,Ruppert M,Kolloch R,Kraft K,Stumpe KO

更新日期：1995-08-01 00:00:00

abstract：:Migration of monocytes into the subendothelial space of the aorta has been considered to be an important event in the development of atherosclerosis. Because hypertension is commonly associated with atherosclerosis, we studied the effect of applied pressure on the migration of monocytes. Direct applied pressure increa...

journal_title：American journal of hypertension

authors： Singhal PC,Sagar P,Gupta S,Arya M,Gupta M,Prasad A,Loona R,Sharma P,Mattana J

更新日期：1997-11-01 00:00:00

abstract：:Renin secretion by the kidney is inhibited by an increase in free intracellular calcium concentration. This increase in free intracellular calcium content may be augmented by serum 1,25-dihydroxyvitamin D. In 10 subjects with high renin hypertension, an increase in dietary sodium intake resulted in an increase in urin...

journal_title：American journal of hypertension

authors： Burgess ED,Hawkins RG,Watanabe M

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:As a serious pregnancy-specific condition, preeclampsia (PE) is a serious pregnancy-specific condition characterized by insufficient trophoblastic invasion and shallow placental implantation. Long noncoding RNA uc.187, which is transcribed from an ultra-conserved region is highly expressed in the placental t...

journal_title：American journal of hypertension

authors： Huang J,Qian Y,Cheng Q,Yang J,Ding H,Jia R

更新日期：2020-04-29 00:00:00

abstract：:We investigated whether the slow pressor action of small doses of angiotensin II (ANG II) administered to rats was accompanied by the development of structural vascular changes. Male Sprague-Dawley rats (350 to 400 g) were given ANG II intraperitoneally, 200 ng/kg/min, for 7 to 10 days or 6 weeks, or 100 ng/kg/min for...

journal_title：American journal of hypertension

authors： Simon G,Cserep G,Limas C

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Hypertension (HTN) is a known major cardiovascular disease risk factor, but prevalence, treatment, and control of HTN among rapidly growing minority groups such as Asian Americans and Hispanics are unknown largely due to either underrepresentation in epidemiologic studies or aggregation of Asian American sub...

journal_title：American journal of hypertension

authors： Zhao B,Jose PO,Pu J,Chung S,Ancheta IB,Fortmann SP,Palaniappan LP

更新日期：2015-05-01 00:00:00

abstract：:We studied how closely changes in electronically monitored physical activity are reflected in changes in blood pressure and heart rate in a group of untreated hypertensive subjects. Thirty-nine hypertensive patients (office blood pressure > 140/ 90 mm Hg) of mean age 57 +/- 10 years (mean +/-SD) wore an ambulatory blo...

journal_title：American journal of hypertension

authors： Mansoor GA,White WB,McCabe EJ,Giacco S

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Previous autopsy studies suggested that a reduced nephron number is associated with increased risk of hypertension and chronic kidney disease. However, the significance of the nephron number estimated from a renal biopsy in patients with hypertensive nephrosclerosis (HNS) has not yet been elucidated. METHOD...

journal_title：American journal of hypertension

authors： Haruhara K,Tsuboi N,Kanzaki G,Koike K,Suyama M,Shimizu A,Miyazaki Y,Kawamura T,Ogura M,Yokoo T

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:The aim of this study was to clarify the response of endothelial connexins to hypertension and antihypertensive drugs. METHODS:Rats remained normotensive (group 1, N = 10) or were made hypertensive using N(omega)-nitro-L-arginine methyl ester (L-NAME) (groups 2 to 4, N = 10/group). Seven weeks later groups ...

journal_title：American journal of hypertension

authors： Yeh HI,Lee PY,Su CH,Tian TY,Ko YS,Tsai CH

更新日期：2006-02-01 00:00:00

abstract：:Arterial stiffness has been known as a sign of cardiovascular risk since the 19th century. Despite this, accurate measurement and clinical utility have only emerged in recent times. Arterial stiffness and its hemodynamic consequences are now established as predictors of adverse cardiovascular outcome. They are easily ...

journal_title：American journal of hypertension

authors： Adji A,O'Rourke MF,Namasivayam M

更新日期：2011-01-01 00:00:00

abstract：:It has been speculated for some time that various antihypertensive medications may have a deleterious effect on respiration during sleep and thereby enhance the apparent association between hypertension and sleep apnea/hypopnea (SAH). However, there are few data to support this contention. The present study used a dou...

journal_title：American journal of hypertension

authors： Bartel PR,Loock M,Becker P,Robinson E,van der Meyden C,Rossouw S

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:The optimal schedule for self-monitoring home BP (SMHBP) readings is enormously important in the diagnosis of different phenotypes related to hypertension. The aim of this study was to determine the prognostic capacity of a 3-day SMHBP schedule when using or suppressing the first-day measurements in compilin...

journal_title：American journal of hypertension

authors： Bayó J,Dalfó A,Barceló MA,Saez M,Roca C,Pallozzi J,Coll-De-Tuero G

更新日期：2020-02-22 00:00:00

abstract：BACKGROUND:Most healthy people exhibit a decrease in systolic blood pressure (SBP) at night. A drop of <10% from mean daytime values, "non-dipping," is associated with kidney disease and cardiovascular events. We hypothesized that non-dipping would predict all-cause mortality. METHODS:Consecutive patients referred for...

journal_title：American journal of hypertension

authors： Brotman DJ,Davidson MB,Boumitri M,Vidt DG

更新日期：2008-01-01 00:00:00

abstract：:The effects of dietary Na+ on 5 alpha- and 5 beta-reductase pathways of aldosterone metabolism in the liver were studied in male rats maintained on low, control, and high Na+ diets. A high Na+ diet caused significant increases in the synthesis of 5 beta-reduced metabolites, primarily 3 alpha, 5 beta-tetrahydroaldoster...

journal_title：American journal of hypertension

authors： Gorsline J,Latif SA,Morris DJ

更新日期：1988-07-01 00:00:00

abstract：:It has been suggested that hyperinsulinemia compensating insulin resistance in glucose metabolism may be a pathogenic factor in essential hypertension. On the other hand, age-associated increases in the prevalence of glucose intolerance and hypertension are also well established. The aim of this study is to clarify th...

journal_title：American journal of hypertension

authors： Miyazaki Y,Hirata A,Murakami H,Fukuoka M,Agata J,Higashiura K,Masuda A,Ura N,Shimamoto K

更新日期：1998-09-01 00:00:00