Changes in 5 alpha- and 5 beta-reductase pathways of aldosterone metabolism by dietary sodium.

abstract：BACKGROUND:High waist circumference (WC) (women: >88 cm; men: >102 cm) increases cardiovascular risk. Less is known about moderate WC (women: 80-88 cm; men: 94-102 cm). Therefore, we examined the association between moderate WC and hypertension prevalence, independent of body mass index (BMI). METHODS:Among 24,247 eli...

journal_title：American journal of hypertension

authors： Levine DA,Calhoun DA,Prineas RJ,Cushman M,Howard VJ,Howard G

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Parathyroid hormone (PTH) stimulates aldosterone secretion in human adrenocortex and is regulated by the renin-angiotensin-aldosterone system. We speculated that measurement of PTH may be a valuable aid in the diagnosis of aldosterone-producing adenoma (APA). METHODS:To test this hypothesis, we recruited 14...

journal_title：American journal of hypertension

authors： Zhang LX,Gu WJ,Li YJ,Wang Y,Wang WB,Wang AP,Shen L,Zang L,Yang GQ,Lu ZH,Dou JT,Mu YM

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:One effort to improve hypertension care in the United States is the development of the "Hypertension Specialist" program with appropriate training and certification of individual physicians. METHODS:We examined the impact of a hypertension clinic on blood pressure (BP) levels and control. RESULTS:By one ye...

journal_title：American journal of hypertension

authors： Bansal N,Tendler BE,White WB,Mansoor GA

更新日期：2003-10-01 00:00:00

abstract：:The increased red blood cell Li+/Na+ exchange found in a subgroup of patients with essential hypertension (EH) may reflect an increased activity of the Na+/H+ exchange. The maximal velocity of the red cells' Na+/H+ (Na+ influx promoted by an outward H+ gradient) and Li+/Na+ (Li+ efflux promoted by external Na+) exchan...

journal_title：American journal of hypertension

authors： Semplicini A,Canessa M,Mozzato MG,Ceolotto G,Marzola M,Buzzaccarini F,Casolino P,Pessina AC

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Hypertension is the most prevalent chronic disease worldwide. Lifestyle behaviors for its prevention and control are recommended within worldwide guidelines. Nevertheless, their combined relationship with blood pressure (BP) level, particularly in the general population, would need more investigations. Our a...

journal_title：American journal of hypertension

authors： Lelong H,Galan P,Kesse-Guyot E,Fezeu L,Hercberg S,Blacher J

更新日期：2015-03-01 00:00:00

abstract：:Compliance is commonly defined as the extent to which a person's behavior coincides with medical or health advice. There is evidence that noncompliance is a common problem with many medications, including antihypertensive treatment. Since noncompliance can have serious adverse effects on patient health it is important...

journal_title：American journal of hypertension

authors： Sanson-Fisher RW,Clover K

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Little is known about hypertension in the HIV-infected population. This study aimed to assess the prevalence of hypertension and related factors in HIV-infected patients. METHODS:In this prospective cross-sectional study, 710 HIV-infected patients (626 on combination antiretroviral therapy and 84 naive) man...

journal_title：American journal of hypertension

authors： Jericó C,Knobel H,Montero M,Sorli ML,Guelar A,Gimeno JL,Saballs P,López-Colomés JL,Pedro-Botet J

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:The prognostic value of left ventricular (LV) concentric remodeling in essential hypertension, and particularly in uncomplicated mild hypertension, is not yet completely clear. We investigated cardiovascular outcome in uncomplicated mild hypertensive patients with normal LV geometry and LV concentric remodel...

journal_title：American journal of hypertension

authors： Pierdomenico SD,Lapenna D,Bucci A,Manente BM,Cuccurullo F,Mezzetti A

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:The effect of age on the augmentation index (AI) differs between young adults and the elderly, and the AI reaches a plateau after the age of 60 years. We examined whether the effects of age and an elevation in blood pressure on the AI differ between young adults and the elderly, between subjects with and wit...

journal_title：American journal of hypertension

authors： Tomiyama H,Odaira M,Kimura K,Matsumoto C,Shiina K,Eguchi K,Miyashita H,Shimada K,Yamashina A

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Vitamin D is involved in blood pressure (BP) regulation. Genetic variations may influence the effect of vitamin D on BP, but data from epidemiologic studies remain inconsistent. METHODS:We conducted a comprehensive genetic association study in the Women's Genome Health Study (WGHS) with genome-wide genotype...

journal_title：American journal of hypertension

authors： Wang L,Chu A,Buring JE,Ridker PM,Chasman DI,Sesso HD

更新日期：2014-11-01 00:00:00

abstract：:Platelet intracellular free calcium concentration [Ca2+]i from patients with essential hypertension has been found to be elevated, but the intracellular effects of this increase are still unclear. As protein phosphorylation is an important regulatory step in cell activation and increased protein phosphorylation has be...

journal_title：American journal of hypertension

authors： Haller H,Lindschau C,Quass P,Distler A

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:In chronic kidney disease, intensive systolic blood pressure (SBP) control reduces mortality at a cost of greater acute kidney injury risk. Kidney transplantation involves implantation of denervated kidneys and immunosuppressive medications that increase acute kidney injury risk. The optimal blood pressure (...

journal_title：American journal of hypertension

authors： Malhotra R,Katz R,Weiner DE,Levey AS,Cheung AK,Bostom AG,Ix JH

更新日期：2019-08-14 00:00:00

abstract：:Left ventricular hypertrophy in patients with hypertension is an important condition. It is associated with significant mortality and carries increased risk for developing nonfatal cardiovascular complications, including coronary heart disease. The pathogenesis of left ventricular hypertrophy is linked to activation o...

journal_title：American journal of hypertension

authors： Dahlöf B

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Subjects with hypertension are frequently obese or insulin resistant, both conditions in which hyperuricemia is common. Obese and insulin-resistant subjects are also known to have blood pressure that is more sensitive to changes in dietary sodium intake. Whether hyperuricemia is a resulting consequence, mode...

journal_title：American journal of hypertension

authors： Todd AS,Walker RJ,MacGinley RJ,Kelly J,Merriman TR,Major TJ,Johnson RJ

更新日期：2017-11-06 00:00:00

abstract：BACKGROUND:Hypertension (HTN) is a known major cardiovascular disease risk factor, but prevalence, treatment, and control of HTN among rapidly growing minority groups such as Asian Americans and Hispanics are unknown largely due to either underrepresentation in epidemiologic studies or aggregation of Asian American sub...

journal_title：American journal of hypertension

authors： Zhao B,Jose PO,Pu J,Chung S,Ancheta IB,Fortmann SP,Palaniappan LP

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:The aims of this study were to document the presence of phospholipase C (PLC) isozymes beta(1), gamma(1), and delta(1) in freshly isolated renal glomeruli and resistance vessels, to compare their expression and activity to that in aorta, and to contrast values between 6-week-old Wistar-Kyoto (WKY) controls a...

journal_title：American journal of hypertension

authors： Peng Z,Dang A,Arendshorst WJ

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:In middle-aged and elderly populations, circulating natriuretic peptide concentrations are negatively associated with several components of the metabolic syndrome. Whether these negative associations are also present in healthy adolescents and young adults from the general population are unknown. METHODS:In...

journal_title：American journal of hypertension

authors： Goharian TS,Goetze JP,Faber J,Andersen LB,Grøntved A,Jeppesen JL

更新日期：2017-06-01 00:00:00

abstract：:The purpose of this study was to determine whether cold-stress stimulation to the soles of paws produces continuous hypertension in rats. Wistar-Kyoto rats were kept in cages with a 0 degrees C floor and 23 degrees C room temperature (cold-stressed group, n = 10) or in cages with 23 degrees C floor and 23 degrees C ro...

journal_title：American journal of hypertension

authors： Kanayama N,Khatun S,Belayet H,She L,Terao T

更新日期：1999-11-01 00:00:00

abstract：:National standards govern the manufacture and marketing of medical devices in the United States, including those for indirect blood pressure measurement in man. There are no comparable standards for devices for recording in laboratory animals. Noninvasive tail cuff blood pressure (BP) recording in the rat is widely ac...

journal_title：American journal of hypertension

authors： Jamieson MJ,Gonzales GM,Jackson TI,Koerth SM,Romano WF,Tan DX,Castillon F 3rd,Skinner MH,Grossmann M,Shepherd AM

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Osteopontin (Opn) is highly upregulated in many different animal models of renal disease, where it is suspected to participate in progression of the disease. In some models, angiotensin II (Ang II) seems to induce the elevated Opn production. Therefore, we examined the regulation of Opn in two-kidney, one-cl...

journal_title：American journal of hypertension

authors： Gauer S,Hartner A,Hauser IA,Fierlbeck W,Eberhardt W,Geiger H

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Pulse pressure/stroke volume indexed to height(2.04) (PP/SVi) is a validated measure of arterial stiffness, but its relation to carotid atherosclerosis is unknown. METHODS:Clinical, echocardiographic, and carotid ultrasound data from 6,209 hypertensive patients without prevalent cardiovascular (CV) disease ...

journal_title：American journal of hypertension

authors： Casalnuovo G,Gerdts E,de Simone G,Izzo R,De Marco M,Giudice R,Trimarco B,De Luca N

更新日期：2012-07-01 00:00:00

abstract：:Our objective was to describe the relationship of arterial stiffness and hypertension in a large, population-based sample of men and women. Hypertension-related increases in arterial stiffness may reflect the distending pressure and/or structural alterations in the artery. Included were 10,712 participants, ages 45 to...

journal_title：American journal of hypertension

authors： Arnett DK,Boland LL,Evans GW,Riley W,Barnes R,Tyroler HA,Heiss G

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Inflammation is an independent risk factor for high blood pressure, and as a consequence inflammatory cytokines could be related with left ventricular hypertrophy (LVH). We sought to assess the association and predictive role of different cytokine levels with LVH in a group of patients with essential hyperte...

journal_title：American journal of hypertension

authors： Roselló-Lletí E,Rivera M,Martínez-Dolz L,González Juanatey JR,Cortés R,Jordán A,Morillas P,Lauwers C,Calabuig JR,Antorrena I,de Rivas B,Portolés M,Bertomeu V

更新日期：2009-04-01 00:00:00

abstract：:This study found that pigs in the early stages of perinephritic hypertension had enhanced plasma norepinephrine (NE) and heart rate (HR) responses to behaviorally arousing stimuli (lifting in a canvas sling) and exercise. In the hypertensive animals, the increase in plasma NE in response to behavioral arousal caused b...

journal_title：American journal of hypertension

authors： Zhao S,Pinto JM,Bergau D,Lown B,Kirby DA

更新日期：1993-10-01 00:00:00

abstract：:It has been suggested that hyperinsulinemia compensating insulin resistance in glucose metabolism may be a pathogenic factor in essential hypertension. On the other hand, age-associated increases in the prevalence of glucose intolerance and hypertension are also well established. The aim of this study is to clarify th...

journal_title：American journal of hypertension

authors： Miyazaki Y,Hirata A,Murakami H,Fukuoka M,Agata J,Higashiura K,Masuda A,Ura N,Shimamoto K

更新日期：1998-09-01 00:00:00

abstract：:High affinity Ca2(+)-activated, Mg2(+)-dependent ATP-ase [Ca2+ + Mg2+)-ATPase) activities were characterized in the membrane fractions of the porcine aorta. The (Ca2+ + Mg2+)-ATPase activity, similar to those found in the plasma membranes of the erythrocyte and the heart, ie, Ca2(+)-pumping ATPase activity, was not fo...

journal_title：American journal of hypertension

authors： Yoshida Y,Sun HT,Imai S

更新日期：1990-08-01 00:00:00

abstract：:It is premature to state that ambulatory blood pressure (ABP) values below a given level should be considered normal, and those above it abnormal, in terms of prognostic implications on cardiovascular (CV) morbidity. We do not know whether CV morbidity in hypertensive subjects with apparently normal ABP (white coat hy...

journal_title：American journal of hypertension

authors： Verdecchia P,Porcellati C

更新日期：1993-06-01 00:00:00

abstract：:The present study evaluated the effects of miconazole, a selective inhibitor of epoxygenase activity, on renal hemodynamics and the pressure-natriuresis response of saline-drinking, uninephrectomized Lyon hypertensive (LH) and Lyon low blood pressure (LL) rats. Infusion of miconazole (final concentration, 1 micromol/L...

journal_title：American journal of hypertension

authors： Messer-Létienne I,Bernard N,Roman RJ,Sassard J,Benzoni D

更新日期：1999-04-01 00:00:00

abstract：:Insulin resistance, the most important factor in metabolic syndrome X, has been considered to raise blood pressure. Recently it was reported that insulin resistance was related to an elevated plasma level of leptin, which is an adipocyte-specific ob gene product and which plays a role in food intake suppression, therm...

journal_title：American journal of hypertension

authors： Agata J,Masuda A,Takada M,Higashiura K,Murakami H,Miyazaki Y,Shimamoto K

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Nocturnal blood pressure (BP) is associated with risk for cardiovascular events. However, the relationship between nocturnal BP in young adults and cognitive function in midlife remains unclear. METHODS:We used data from the ambulatory BP monitoring substudy of the Coronary Artery Risk Development in Young ...

journal_title：American journal of hypertension

authors： Yano Y,Ning H,Muntner P,Reis JP,Calhoun DA,Viera AJ,Levine DA,Jacobs DR Jr,Shimbo D,Liu K,Greenland P,Lloyd-Jones D

更新日期：2015-10-01 00:00:00