Moderate waist circumference and hypertension prevalence: the REGARDS Study.

Abstract:

BACKGROUND:High waist circumference (WC) (women: >88 cm; men: >102 cm) increases cardiovascular risk. Less is known about moderate WC (women: 80-88 cm; men: 94-102 cm). Therefore, we examined the association between moderate WC and hypertension prevalence, independent of body mass index (BMI). METHODS:Among 24,247 eligible adults 45-84 years old, when recruited from January 2003 to October 2007 in the population-based REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort, we examined hypertension prevalence (systolic blood pressure (BP) ≥140 mm Hg, or diastolic BP ≥90 mm Hg, or self-reported antihypertensive medication use) by WC before and after stratification by BMI (normal: 18.5-24.9; overweight: 25-29.9; obese class I: 30-34.9). Logistic regression adjusted associations between WC, BMI, and hypertension prevalence for age, race, sex, region, income, education, cigarette smoking, glomerular filtration rate, alcohol use, and physical activity. RESULTS:Overall, hypertension prevalence was 44% among those with low WC (n = 8,068), 55% with moderate WC (n = 6,488), and 66% with high WC (n = 9,691). After full adjustment, moderate WC was independently associated with hypertension prevalence among persons with normal BMI, (adjusted odds ratio (aOR), 1.49; 95% confidence interval (CI), 1.31-1.70), overweight BMI (aOR, 1.80; 95% CI, 1.64-1.98), and obese class I BMI (aOR, 2.28; 95%CI, 1.96-2.65) (referent: low WC-normal BMI). The moderate WC-hypertension association was observed in blacks and whites and in men and women. CONCLUSION:Moderate WC is associated with hypertension prevalence independent of BMI and several hypertension risk factors in middle-aged and older adults.

journal_name

Am J Hypertens

authors

Levine DA,Calhoun DA,Prineas RJ,Cushman M,Howard VJ,Howard G

doi

10.1038/ajh.2010.258

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

482-8

issue

4

eissn

0895-7061

issn

1941-7225

pii

ajh2010258

journal_volume

24

pub_type

杂志文章
  • The effect of sodium supplementation on glucose tolerance and insulin concentrations in patients with hypertension and diabetes mellitus.

    abstract::Severe short-term sodium restriction or extreme sodium loading may alter glucose tolerance and insulin resistance in patients with hypertension, but it is unclear whether variations in sodium intake within the clinically observed range affect glucose tolerance. To examine this issue, 21 patients with primary hypertens...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0895-7061(01)01310-3

    authors: Ames RP

    更新日期:2001-07-01 00:00:00

  • Lack of difference in oxalate-dependent Ca2+ uptake by membrane homogenate of African-American and white subjects.

    abstract::In order to further characterize previously described racial differences in intracellular Ca2+ homeostasis, the activity of sarcoplasmic-endoplasmic reticulum Ca2+-ATPase was measured in cultured skin fibroblasts from normotensive African-Americans and whites. Cells originated from apparently healthy, normotensive Afr...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/s0895-7061(96)00415-3

    authors: Yang XY,Aviv A,Hopp L

    更新日期:1997-04-01 00:00:00

  • Red blood cell Na+/H+ and Li+/Na+ exchange in patients with essential hypertension.

    abstract::The increased red blood cell Li+/Na+ exchange found in a subgroup of patients with essential hypertension (EH) may reflect an increased activity of the Na+/H+ exchange. The maximal velocity of the red cells' Na+/H+ (Na+ influx promoted by an outward H+ gradient) and Li+/Na+ (Li+ efflux promoted by external Na+) exchan...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/2.12.903

    authors: Semplicini A,Canessa M,Mozzato MG,Ceolotto G,Marzola M,Buzzaccarini F,Casolino P,Pessina AC

    更新日期:1989-12-01 00:00:00

  • Metabolic syndrome and insulin resistance in the TROPHY sub-study: contrasting views in patients with high-normal blood pressure.

    abstract:BACKGROUND:Although insulin resistance and metabolic syndrome are often used synonymously, concordance is not established. METHODS:Metabolic, hemodynamic, and hormonal data were analyzed on 141 patients in the Trial of Preventing Hypertension (TROPHY) Sub-Study with high-normal blood pressure (BP) (130 to 139/85 to 89...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/j.amjhyper.2004.08.008

    authors: Egan BM,Papademetriou V,Wofford M,Calhoun D,Fernandes J,Riehle JE,Nesbitt S,Michelson E,Julius S,TROPHY Sub-study Investigative Team.

    更新日期:2005-01-01 00:00:00

  • Age is a major determinant of the divergent blood pressure responses to varying salt intake in essential hypertension.

    abstract::Blood pressure responses to 1 week of low (20 mmol sodium/day) and high (300 mmol sodium/day) salt intake were investigated in a double-blind, randomized study in 46 white, nonobese subjects with essential hypertension (13 women, 33 men; mean age 45.3 +/- 2.2 years, age range 25 to 80 years). The individuals were clas...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0895-7061(95)00213-9

    authors: Overlack A,Ruppert M,Kolloch R,Kraft K,Stumpe KO

    更新日期:1995-08-01 00:00:00

  • Oxidative stress in hypertensive,diabetic, and diabetic hypertensive rats.

    abstract:BACKGROUND:Reactive oxygen species play a key role in the formation of endothelial dysfunction accompanying diabetes mellitus, hypertension, and other cardiovascular diseases. METHOD:This study compares oxidative stress (OS) in Wistar-Kyoto rats (WKY), spontaneously hypertensive rats (SHR), non-insulin-dependent Cohen...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/j.amjhyper.2003.07.013

    authors: Friedman J,Peleg E,Kagan T,Shnizer S,Rosenthal T

    更新日期:2003-12-01 00:00:00

  • Aortic Fibrosis, Induced by High Salt Intake in the Absence of Hypertensive Response, is Reduced by a Monoclonal Antibody to Marinobufagenin.

    abstract:BACKGROUND:Marinobufagenin (MBG) is an endogenous Na/K-ATPase inhibitor, a natriuretic and a vasoconstrictor. MBG is implicated in salt-sensitive hypertension, cardiac hypertrophy, and initiate the pro-fibrotic signaling. Previously it was demonstrated that immunoneutralization of an endogenous MBG by 3E9 anti-MBG-anti...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/hpv155

    authors: Grigorova YN,Juhasz O,Zernetkina V,Fishbein KW,Lakatta EG,Fedorova OV,Bagrov AY

    更新日期:2016-05-01 00:00:00

  • Childhood predictors of high blood pressure.

    abstract::Longitudinal studies in children have tracked blood pressure through childhood and from childhood into adult life. However, many children do not maintain their rank during these periods of observation. Several of the factors contributing to maintenance of rank order are reviewed, such as initial level of blood pressur...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1093/ajh/4.11s.608s

    authors: Mahoney LT,Clarke WR,Burns TL,Lauer RM

    更新日期:1991-11-01 00:00:00

  • PTH Is a Promising Auxiliary Index for the Clinical Diagnosis of Aldosterone-Producing Adenoma.

    abstract:BACKGROUND:Parathyroid hormone (PTH) stimulates aldosterone secretion in human adrenocortex and is regulated by the renin-angiotensin-aldosterone system. We speculated that measurement of PTH may be a valuable aid in the diagnosis of aldosterone-producing adenoma (APA). METHODS:To test this hypothesis, we recruited 14...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/hpv146

    authors: Zhang LX,Gu WJ,Li YJ,Wang Y,Wang WB,Wang AP,Shen L,Zang L,Yang GQ,Lu ZH,Dou JT,Mu YM

    更新日期:2016-05-01 00:00:00

  • Gender differences in insulin-stimulated glucose utilization among African-Americans.

    abstract::The purpose of this study was to determine whether there are gender differences in plasma insulin levels or insulin resistance in young adult African-Americans. Male (n = 53) and female (n = 45) subjects (age 23 to 28 years) included normotensives (N, blood pressure [BP] < 135/85 mm Hg) and borderline hypertensives (B...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/7.11.948

    authors: Falkner B,Hulman S,Kushner H

    更新日期:1994-11-01 00:00:00

  • Angiotensin-converting enzyme inhibitors. Emerging differences and new compounds.

    abstract::Angiotensin-converting enzyme inhibitors (ACEIs), introduced in clinical practice in 1980, are a relatively new class of drugs. They have been useful in the treatment of hypertension, where they are effective monotherapy in 40% to 50% of the patients and in combination therapy in up to 90%. They are also useful in the...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1093/ajh/2.1.57

    authors: Kostis JB

    更新日期:1989-01-01 00:00:00

  • Role of endothelin-1 in hypertension and vascular disease.

    abstract::Endothelin-1 (ET-1) is a powerful vasoconstrictor peptide and regulator of blood flow that plays an important role in blood pressure (BP) elevation in some models of experimental hypertension such as DOCA-salt rat, DOCA-salt-treated spontaneously hypertensive rats (SHR), stroke-prone SHR, Dahl salt-sensitive rats, ang...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1016/s0895-7061(01)02074-x

    authors: Schiffrin EL

    更新日期:2001-06-01 00:00:00

  • Heritability of the retinal microcirculation in Flemish families.

    abstract:BACKGROUND:Few population studies have described the heritability and intrafamilial concordance of the retinal microvessels, or the genetic or environmental correlations of the phenotypes of these vessels. METHODS:We randomly selected 413 participants from 70 families (mean age, 51.5 years; 50.1% women) from a Flemish...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/hps064

    authors: Liu YP,Kuznetsova T,Jin Y,Thijs L,Asayama K,Gu YM,Bochud M,Verhamme P,Struijker-Boudier HA,Staessen JA

    更新日期:2013-03-01 00:00:00

  • Blood pressure and cognitive functioning among independent elderly.

    abstract:BACKGROUND:The morbidity and mortality benefits of blood pressure (BP) control for the elderly is well documented. The cognitive consequences of hypertension control in this population, however, are still under debate. We aim to study the association between BP and cognitive performance in the elderly. Specifically, we...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/s0895-7061(03)01005-7

    authors: Paran E,Anson O,Reuveni H

    更新日期:2003-10-01 00:00:00

  • Ambulatory blood pressure monitoring in a nonacademic setting. Effects of age and sex.

    abstract::Twenty-four-hour ambulatory blood pressure measurements (ABPM) are likely to eliminate the stress of visits and observer bias in office blood pressure (BP) recordings, allow consideration of the circadian variability in BP, and correlate well with target organ damage. To define the prevalence of "white coat" hypertens...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/5.9.616

    authors: Khoury S,Yarows SA,O'Brien TK,Sowers JR

    更新日期:1992-09-01 00:00:00

  • Visit-to-visit blood pressure variability, silent cerebral injury, and risk of stroke.

    abstract::Apart from the well-known role of hypertension in cerebrovascular disease, visit-to-visit blood pressure (BP) variability is emerging as an independent risk factor for stroke. Although the underlying mechanism is not fully understood, artery remodeling is thought to be closely involved in the relationship between visi...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1093/ajh/hpt167

    authors: Nagai M,Kario K

    更新日期:2013-12-01 00:00:00

  • Characterization of a Na+/K+-ATPase inhibitor from human plasma: preliminary data.

    abstract::The role of an endogenous sodium pump inhibitor in the pathogenesis of hypertension has been reported in several papers. Unfortunately, because of the unknown structure and lack of biochemical characterization, some discrepancies have arisen. In this study we report a method to obtain extracts from human plasma that a...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/1.3.56s

    authors: Boschi S,Munarini A,Borghi C,Strocchi E,Costa FV,Mussi A,Ettore A

    更新日期:1988-07-01 00:00:00

  • Quinapril prevents stroke both during and after the treatment period in stroke-prone spontaneously hypertensive rats.

    abstract::The effects of long-term oral administration of quinapril on the occurrence of stroke and on mortality were investigated in young salt-loaded stroke-prone spontaneously hypertensive rats (SHR-SPs) during the treatment period (8th-34th week of age) and up to 6 weeks thereafter. Simultaneously, blood pressure, saline in...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/6.11.951

    authors: Vacher E,Fornes P,Domergue V,Richer C,Bruneval P,Giudicelli JF

    更新日期:1993-11-01 00:00:00

  • D3 dopamine receptor regulation of ETB receptors in renal proximal tubule cells from WKY and SHRs.

    abstract:BACKGROUND:The dopaminergic and endothelin systems, by regulating sodium transport in the renal proximal tubule (RPT), participate in the control of blood pressure. The D(3) and ETB receptors are expressed in RPTs, and D(3) receptor function in RPTs is impaired in spontaneously hypertensive rats (SHRs). Therefore, we t...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1038/ajh.2009.80

    authors: Yu C,Yang Z,Ren H,Zhang Y,Han Y,He D,Lu Q,Wang X,Wang X,Yang C,Asico LD,Hopfer U,Eisner GM,Jose PA,Zeng C

    更新日期:2009-08-01 00:00:00

  • Accuracy of anthropometric indexes of obesity to predict diabetes mellitus type 2 among men and women with hypertension.

    abstract:BACKGROUND:Anthropometric measurements and indexes that assess excess of adiposity are associated with cardiovascular risk factors, and predict diabetes mellitus. METHODS:This cross-sectional study reported the performance of adiposity indexes to detect or turn diabetes unlikely in patients with hypertension. Patients...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1038/ajh.2010.212

    authors: Marcadenti A,Fuchs SC,Moreira LB,Wiehe M,Gus M,Fuchs FD

    更新日期:2011-02-01 00:00:00

  • Rebound weight gain as associated with high plasma norepinephrine levels that are mediated through polymorphisms in the beta2-adrenoceptor.

    abstract:BACKGROUND:A successful weight loss program is essential treatment for obesity-related diseases, but it is well known that the majority of individuals do not succeed in weight loss maintenance. The present study evaluates hormonal mechanisms and the relationship of beta2-adrenoceptor polymorphisms involved in individua...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/j.amjhyper.2005.05.006

    authors: Masuo K,Katsuya T,Kawaguchi H,Fu Y,Rakugi H,Ogihara T,Tuck ML

    更新日期:2005-11-01 00:00:00

  • Factors Associated With Physician Recommendation of Home Blood Pressure Monitoring and Blood Pressure in the US Population.

    abstract:BACKGROUND:Hypertension guidelines recommend home blood pressure monitoring (HBPM) to help achieve blood pressure (BP) control. We hypothesized that HBPM use with a physician recommendation would be associated with lower BP and greater medication adherence. METHODS:We used data from 6,320 adults with hypertension in t...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/hpaa093

    authors: Tang O,Foti K,Miller ER,Appel LJ,Juraschek SP

    更新日期:2020-09-10 00:00:00

  • Relation of C-reactive protein to oxidative stress and to endothelial activation in essential hypertension.

    abstract:BACKGROUND:C-reactive protein (CRP) predicts cardiovascular outcome. Oxidative stress is considered to be involved in endothelial alteration. We hypothesized that in essential hypertension (EH), oxidative stress, as measured by 8-iso-prostaglandin-F(2alpha) (8-iso-PGF(2alpha)), should be associated with increased CRP a...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/j.amjhyper.2005.09.005

    authors: Cottone S,Mulè G,Nardi E,Vadalà A,Guarneri M,Briolotta C,Arsena R,Palermo A,Riccobene R,Cerasola G

    更新日期:2006-03-01 00:00:00

  • Effects of dietary fish oil on Rb+ efflux from aorta of stroke prone spontaneously hypertensive rats.

    abstract::The effect of fish oil on potassium efflux and basal tension in aortas from stroke prone spontaneously hypertensive rats (SHRSP) was evaluated. Four-week-old male Wistar-Kyoto rats (WKY) and SHRSP were divided into two groups: one received a 5% corn oil diet; the other a 5% menhaden oil diet. After 15 weeks, mean syst...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/5.7.473

    authors: Smith JM,Paulson DJ,Labak S

    更新日期:1992-07-01 00:00:00

  • Disparate effects of weight loss on insulin sensitivity and erythrocyte sodium-lithium countertransport activity.

    abstract::Previous investigations have demonstrated an association between impaired insulin sensitivity and elevated erythrocyte sodium-lithium countertransport (Na(+)-Li+ CT) activity. It has been speculated that insulin resistance and endogenous hyperinsulinemia are causally related to the development of elevated Na(+)-Li+ CT...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/5.10.754

    authors: Wolpert HA,Steen SN,Istfan NW,Simonson DC

    更新日期:1992-10-01 00:00:00

  • Treatment of mild hypertension with urapidil or captopril.

    abstract::The aim of this study was to compare the efficacy (lowering diastolic blood pressure to 90 mm Hg or less) of urapidil, a postsynaptic alpha-blocker with central action with that of captopril in a randomized, double-blind, multicenter study. Two hundred ninety-five essential hypertensives (WHO I/II) (140 male, 155 fema...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/ajh/1.3.233s

    authors: Rosenthal J,Schäfer N,Haerlin R,Wurst W,Solleder P

    更新日期:1988-07-01 00:00:00

  • Blood pressure control in the hypertension clinic.

    abstract:BACKGROUND:One effort to improve hypertension care in the United States is the development of the "Hypertension Specialist" program with appropriate training and certification of individual physicians. METHODS:We examined the impact of a hypertension clinic on blood pressure (BP) levels and control. RESULTS:By one ye...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/s0895-7061(03)01030-6

    authors: Bansal N,Tendler BE,White WB,Mansoor GA

    更新日期:2003-10-01 00:00:00

  • Plasma pentraxin3 and arterial stiffness in men with obstructive sleep apnea.

    abstract:BACKGROUND:Obstructive sleep apnea (OSA) induces inflammation and vascular damage that might contribute to an increased risk of cardiovascular disease (CVD). However, the mechanisms linking OSA and CVD are not fully understood. Pentraxin3 may play a significant role in vascular inflammation and damage. Currently, there...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1038/ajh.2010.248

    authors: Kasai T,Inoue K,Kumagai T,Kato M,Kawana F,Sagara M,Ishiwata S,Ohno M,Yamaguchi T,Momomura S,Narui K

    更新日期:2011-04-01 00:00:00

  • Antihypertensive Drug Therapy. The effect of JNC criteria on prescribing patterns and patient status through the first year.

    abstract::This study was designed to evaluate the impact of the protocol-driven antihypertensive therapy on outcomes guided by the Joint National Committee (JNC) on Detection, Evaluation, and Treatment of high blood pressure. In a systematic hypertension control program for union employees conducted in New York City, untreated ...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章

    doi:10.1016/0895-7061(95)00438-6

    authors: Alderman MH,Madhavan S,Cohen H

    更新日期:1996-05-01 00:00:00

  • Increase of calmodulin activator in hypertension. Modulation by dietary sodium and calcium.

    abstract::The aim of this study was to investigate the effects of dietary calcium and sodium on blood pressure (BP) in normotensive rats (Wistar, WKY), spontaneously hypertensive rats (SHR) and Dahl rats and on calmodulin (CaM) activator, a newly-discovered hydrophobic compound that increases CaM activity in SHR and spontaneous...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/3.8.210

    authors: Chang E,Kunes J,Hamet P,Tremblay J

    更新日期:1990-08-01 00:00:00