Angiotensin-converting enzyme inhibitors. Emerging differences and new compounds.

abstract：:Salt-sensitive persons have lower plasma renin activity than salt-resistant persons and their plasma renin activity increases less with a low sodium diet or volume depletion, compared to salt-resistant individuals. However, the time course of the renin response to acute volume contraction has not been studied in human...

journal_title：American journal of hypertension

authors： Schorr U,Schultz C,Sharma AM

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Hypertension and smoking independently contribute to the risk of stroke. Our objective was to investigate home blood pressure (HBP) levels, day-by-day BP variability, and smoking in the prediction of stroke in Japanese men. METHODS:In this study, 902 men (mean age, 58.6 years) without a past history of stro...

journal_title：American journal of hypertension

authors： Hashimoto T,Kikuya M,Ohkubo T,Satoh M,Metoki H,Inoue R,Asayama K,Kanno A,Obara T,Hirose T,Hara A,Hoshi H,Totsune K,Satoh H,Sato H,Imai Y

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Sleep apnea is being studied as a risk factor for hypertension. This observational chart review was conducted to determine the long-term effects of continuous positive airway pressure (CPAP) treatment on blood pressure (BP) in a sample of sleep apnea patients from urban and rural populations. METHODS:This s...

journal_title：American journal of hypertension

authors： Dhillon S,Chung SA,Fargher T,Huterer N,Shapiro CM

更新日期：2005-05-01 00:00:00

abstract：:Conflicting reports exist as to whether air traffic controllers (ATC) have an increase in blood pressure (BP) and prevalence of hypertension because of the stressful nature of their job. We have addressed the issue in male ATC working at the Linate airport of Milan. A total of 80 ATC participated, and the 24 h blood p...

journal_title：American journal of hypertension

authors： Sega R,Cesana G,Costa G,Ferrario M,Bombelli M,Mancia G

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:The mechanisms by which heme oxygenase (HO) improves glucose metabolism in essential hypertension are not completely understood. Because dysfunctional insulin signaling is associated with elevated inflammation and high cholesterol and triglycerides, we investigated the effects of HO on the proinflammatory ma...

journal_title：American journal of hypertension

authors： Ndisang JF,Mishra M

更新日期：2013-09-01 00:00:00

abstract：:In an in-depth examination to better define the renal effects of mild hypertension, we used urinary proteins to indicate damage to the glomerulus (albumin), tubular reabsorption capability (retinol-binding protein), and turnover of tubular tissue (alanine aminopeptidase and N-acetyl-beta-D-glucosaminidase) in a group ...

journal_title：American journal of hypertension

authors： Mueller PW,Hall WD,Caudill SP,MacNeil ML,Arepally A

更新日期：1995-11-01 00:00:00

abstract：:The purpose of this double-blind, forced titration study was to compare the antihypertensive effect duration of candesartan cilexetil, which has a longlasting binding to the human AT1-receptor, to that of losartan on ambulatory BP (ABP) not only during the 24-h dosing interval but also during the day of a missed dose ...

journal_title：American journal of hypertension

authors： Lacourcière Y,Asmar R

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Pregnancy-induced hypertension (PIH) is associated with chronic hypertension (HTN) and cardiovascular complications. We investigated the factors that predict the development of chronic HTN in women with PIH. METHODS:The study population comprised 108 women with PIH and 87 healthy age-matched women control s...

journal_title：American journal of hypertension

authors： Shopen N,Schiff E,Koren-Morag N,Grossman E

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Left ventricular (LV) hypertrophy and impaired diastolic function may occur early in systemic hypertension, but longitudinal studies are missing. METHODS:We performed an echocardiographic follow-up study in young initially normotensive male offspring of hypertensive (OHyp) (n = 25) and normotensive (ONorm) ...

journal_title：American journal of hypertension

authors： Aeschbacher BC,Hutter D,Fuhrer J,Weidmann P,Delacrétaz E,Allemann Y

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Recently, the central augmentation index (AIx) has been reported to show a nonlinear correlation with age. We investigated whether the AIx of the central artery changes with the progression of atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits. METHODS:We simultaneously recorded pre...

journal_title：American journal of hypertension

authors： Katsuda S,Miyake M,Kobayashi D,Hazama A,Kusanagi M,Takazawa K

更新日期：2013-03-01 00:00:00

abstract：:Inhibition of calcineurin-mediated signaling in T lymphocytes is a major mechanism of cyclosporine A (CsA)-induced immunosuppression, and previous rat studies have suggested that inhibition of calcineurin-mediated signaling in central neuronal pools involved in blood pressure regulation plays an important role in caus...

journal_title：American journal of hypertension

authors： Zhang W,Victor RG

更新日期：2000-09-01 00:00:00

abstract：:Serotonin-containing neurons in the central nervous system are grouped into a number of discrete and distinctive collections with cell bodies in the brainstem and projections passing to many regions of the brain and spinal cord. Evidence is presented that activation of one projection of serotonin-containing neurons fr...

journal_title：American journal of hypertension

authors： Chalmers JP,Pilowsky PM,Minson JB,Kapoor V,Mills E,West MJ

更新日期：1988-01-01 00:00:00

abstract：:To evaluate the existence of a relationship between atrial natriuretic factor (ANF) and plasma Na+/K+ATPase inhibitory activity in humans, we examined the hemodynamic and humoral response to volume expansion in 41 borderline hypertensive patients (BHT) with either normal (n = 33) or low plasma renin activity (n = 8). ...

journal_title：American journal of hypertension

authors： Borghi C,Boschi S,Costa FV,Ambrosioni E

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Feeding stroke-prone spontaneously hypertensive rats (SHRSP) a diet rich in fructose results in a profound glucose intolerance not observed in the normotensive Wistar Kyoto (WKY) strain. The aim of this study was to investigate the role of the liver in the underlying mechanisms in the SHRSP. METHODS:SHRSP a...

journal_title：American journal of hypertension

authors： Brosnan MJ,Carkner RD

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Hypertensive disorders of pregnancy, including preeclampsia (PE), affect approximately 7-10% of pregnancies in the US. Clinical and experimental studies strongly suggest that the maternal immune system plays a role in the development of these disorders; however, few therapeutic options exist aside from deliv...

journal_title：American journal of hypertension

authors： Tinsley JH,Chiasson VL,South S,Mahajan A,Mitchell BM

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Circulating blood levels of human urotensin II (U-II), the most potent vasoconstrictor peptide identified to date, are increased in patients with essential hypertension. Our previous studies showed that U-II accelerates human macrophage foam cell formation and vascular smooth muscle cell proliferation, sugge...

journal_title：American journal of hypertension

authors： Suguro T,Watanabe T,Ban Y,Kodate S,Misaki A,Hirano T,Miyazaki A,Adachi M

更新日期：2007-02-01 00:00:00

abstract：:In the present study we examined whether the angiotensin I converting enzyme inhibitor, captopril, would protect stroke-prone spontaneously hypertensive rats (SHRSP) from stroke and renal pathology over a 26-week period. In the control group of six untreated SHRSP fed Stroke-Prone Rodent Diet and 1% NaCl drinking solu...

journal_title：American journal of hypertension

authors： Stier CT Jr,Chander P,Gutstein WH,Levine S,Itskovitz HD

更新日期：1991-08-01 00:00:00

abstract：:Pneumonia is a major direct cause of death in the elderly. Although aspiration based on a reduced cough reflex is one of the causes of pneumonia in the elderly, there are few studies of angiotensin-I converting enzyme inhibitors (ACE inhibitors), which are antihypertensive drugs that induce cough, as a factor influenc...

journal_title：American journal of hypertension

authors： Okaishi K,Morimoto S,Fukuo K,Niinobu T,Hata S,Onishi T,Ogihara T

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Despite an association between visit-to-visit blood pressure (BP) variability (VV-BPV) and cardiovascular (CV) outcomes, many studies performed during the past 4 years have shown conflicting results. This study investigated the impact of VV-BPV on CV outcomes in the Korean National Health Insurance Service (...

journal_title：American journal of hypertension

authors： Choi S,Shin J,Choi SY,Sung KC,Ihm SH,Kim KI,Kim YM

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The renal resistive index (RI) measured using Doppler ultrasonography has been used as a diagnostic tool in the daily work-up of kidney diseases. A better understanding of its relationship with preclinical organ damage may help in determining overall cardiovascular risk in hypertensive patients. METHODS:We ...

journal_title：American journal of hypertension

authors： Doi Y,Iwashima Y,Yoshihara F,Kamide K,Takata H,Fujii T,Kubota Y,Nakamura S,Horio T,Kawano Y

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Aging is a major risk factor for the development of arterial stiffness and vascular disease, and it is related to the upregulation of matrix metalloproteinase-2 (MMP-2) in the aorta of rats and nonhuman primates. This study aimed to determine whether MMP activity in the human vasculature changes with aging. ...

journal_title：American journal of hypertension

authors： McNulty M,Spiers P,McGovern E,Feely J

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:African-American men have stiffer arteries than white men at rest. We sought to test the hypothesis that reductions in stiffness after aerobic exercise may be attenuated in African-American (AA) men compared with white (W) men. METHODS:Twenty-four young men (age 22+/-1.0 years; 12 AA and 12 W) underwent mea...

journal_title：American journal of hypertension

authors： Heffernan KS,Jae SY,Fernhall B

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:The association between hypertension (HTN) and inflammatory biomarkers (interleukin-6 [IL-6] and high-sensitivity C-reactive protein [hsCRP]) in HIV-positive persons with CD4+ count >500 cells/mm3 is unknown. METHODS:We studied HTN in participants of the Strategic Timing of AntiRetroviral Treatment (START) ...

journal_title：American journal of hypertension

authors： Ghazi L,Baker JV,Sharma S,Jain MK,Palfreeman A,Necsoi C,Murray DD,Neaton JD,Drawz PE

更新日期：2020-01-01 00:00:00

abstract：:To clarify the function of polymorphonuclear leukocytes (PMN) in spontaneously hypertensive rats (SHR) and the effect of beraprost sodium (BS) on these functions, we examined superoxide anion (O2-) production and adherent activity by PMN, as well as modification of these functions by BS ex vivo and in vitro. In study ...

journal_title：American journal of hypertension

authors： Ohmori M,Kitoh Y,Kawaguchi A,Harada K,Sugimoto K,Fujimura A

更新日期：2001-07-01 00:00:00

abstract：:Insulin resistance, the most important factor in metabolic syndrome X, has been considered to raise blood pressure. Recently it was reported that insulin resistance was related to an elevated plasma level of leptin, which is an adipocyte-specific ob gene product and which plays a role in food intake suppression, therm...

journal_title：American journal of hypertension

authors： Agata J,Masuda A,Takada M,Higashiura K,Murakami H,Miyazaki Y,Shimamoto K

更新日期：1997-10-01 00:00:00

abstract：:Increased insulinemic response to an oral glucose load has been demonstrated in Dahl salt-sensitive hypertensive rats. To determine whether this abnormality is mediated at the level of the insulin receptor, we compared insulin receptor binding and mRNA levels in tissues of Dahl salt-sensitive rats (DS) and in their no...

journal_title：American journal of hypertension

authors： Sechi LA,Griffin CA,Zingaro L,Catena C,De Carli S,Schambelan M,Bartoli E

更新日期：1997-11-01 00:00:00

abstract：:Experimental research using in vitro and in vivo models of vascular injury have delineated several common mechanisms that characterize the arterial damage in diseases such as atherosclerosis and hypertension. Changes in endothelial permeability, smooth muscle cell proliferation, and accumulation of connective tissue m...

journal_title：American journal of hypertension

authors： Weinstein DB,Heider JG

更新日期：1989-03-01 00:00:00

abstract：:Hyperinsulinemia and dyslipidemia are known to be associated with essential hypertension but their role in pregnancy-induced hypertension remains unclear. We performed a case-control study comparing cholesterol, insulin, and glucose levels in the early third trimester of pregnancy among 31 women who developed pregnanc...

journal_title：American journal of hypertension

authors： Solomon CG,Carroll JS,Okamura K,Graves SW,Seely EW

更新日期：1999-03-01 00:00:00

abstract：:Compliance is commonly defined as the extent to which a person's behavior coincides with medical or health advice. There is evidence that noncompliance is a common problem with many medications, including antihypertensive treatment. Since noncompliance can have serious adverse effects on patient health it is important...

journal_title：American journal of hypertension

authors： Sanson-Fisher RW,Clover K

更新日期：1995-10-01 00:00:00

abstract：:Responses of renin release and blood pressure to aspirin DL-lysine (ASP) were examined to find out if the responses could help in the differentiation between unilateral renovascular hypertension (RVH) and hyperreninemic essential hypertension (EHT). The two studies involved ten patients with unilateral RVH, eight with...

journal_title：American journal of hypertension

authors： Imanishi M,Ohta M,Kawamura M,Akabane S,Matsushima Y,Kuramochi M,Kojima S,Kimura K,Takamiya M,Ito K

更新日期：1991-09-01 00:00:00