The effect of sodium supplementation on glucose tolerance and insulin concentrations in patients with hypertension and diabetes mellitus.

abstract：BACKGROUND:Adiposity measures are associated with increased pediatric blood pressure (BP). However, this correlation can be confounded by the relationship of both variables to height. We evaluated whether adiposity and anthropometric measures were associated with pediatric BP before and after adjusting each value for h...

journal_title：American journal of hypertension

authors： Willig AL,Casazza K,Dulin-Keita A,Franklin FA,Amaya M,Fernandez JR

更新日期：2010-08-01 00:00:00

abstract：:Left ventricular hypertrophy in patients with hypertension is an important condition. It is associated with significant mortality and carries increased risk for developing nonfatal cardiovascular complications, including coronary heart disease. The pathogenesis of left ventricular hypertrophy is linked to activation o...

journal_title：American journal of hypertension

authors： Dahlöf B

更新日期：2001-02-01 00:00:00

abstract：BACKGROUD:Declining renal function is an independent risk factor for all-cause mortality in cardiovascular disease. Visfatin has been described as a marker of inflammation and endothelial dysfunction, but whether circulating visfatin levels are predictive to a subsequent decline in renal function remains unclear. METH...

journal_title：American journal of hypertension

authors： Hsu CY,Huang PH,Chen TH,Chiang CH,Leu HB,Huang CC,Chen JW,Lin SJ

更新日期：2016-04-01 00:00:00

abstract：:Increased insulinemic response to an oral glucose load has been demonstrated in Dahl salt-sensitive hypertensive rats. To determine whether this abnormality is mediated at the level of the insulin receptor, we compared insulin receptor binding and mRNA levels in tissues of Dahl salt-sensitive rats (DS) and in their no...

journal_title：American journal of hypertension

authors： Sechi LA,Griffin CA,Zingaro L,Catena C,De Carli S,Schambelan M,Bartoli E

更新日期：1997-11-01 00:00:00

abstract：:To study potential ionic factors predisposing to vascular disease in hypertension, particularly among black subjects, we used a recently developed combined magnesium and calcium specific, ion selective electrode apparatus to measure extracellular ionized calcium (Ca-ion), ionized magnesium (Mg-ion), and Ca-ion/Mg-ion ...

journal_title：American journal of hypertension

authors： Resnick LM,Bardicef O,Altura BT,Alderman MH,Altura BM

更新日期：1997-12-01 00:00:00

abstract：:Previous investigations have demonstrated an association between impaired insulin sensitivity and elevated erythrocyte sodium-lithium countertransport (Na(+)-Li+ CT) activity. It has been speculated that insulin resistance and endogenous hyperinsulinemia are causally related to the development of elevated Na(+)-Li+ CT...

journal_title：American journal of hypertension

authors： Wolpert HA,Steen SN,Istfan NW,Simonson DC

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:The brain is perfused at high-volume flow throughout systole and diastole. We explored the association of blood flow in the middle cerebral artery (MCA) with the pulsatile components of blood pressure in the systemic circulation and indices of arterial stiffness. METHODS:We enrolled 334 untreated subjects (...

journal_title：American journal of hypertension

authors： Xu TY,Staessen JA,Wei FF,Xu J,Li FH,Fan WX,Gao PJ,Wang JG,Li Y

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The collateral circulation is important in maintenance of blood supply to the ischemic kidney distal to renal artery stenosis (RAS). Obesity metabolic syndrome (MetS) preserves renal blood flow (RBF) in the stenotic kidney, but whether this is related to an increase of collateral vessel growth is unknown. We...

journal_title：American journal of hypertension

authors： Zhang X,Kim SR,Ferguson CM,Ebrahimi B,Hedayat AF,Lerman A,Lerman LO

更新日期：2018-11-13 00:00:00

abstract：BACKGROUND:Progression of atherosclerosis with increased arterial stiffness is associated with increased cardiovascular morbidity and mortality in patients with chronic kidney disease (CKD). Compliance index (CI) derived from digital volume pulse (DVP), measuring the relationship between volume and pressure changes in ...

journal_title：American journal of hypertension

authors： Wang MC,Wu AB,Cheng MF,Chen JY,Ho CS,Tsai WC

更新日期：2011-05-01 00:00:00

abstract：:To study the circulating humoral factor modifying transmembrane sodium transport, plasma was obtained from 12 patients with essential hypertension (EH) fed a high sodium diet (NaCl 15 to 17 g/d) for seven days and thereafter a low sodium diet (NaCl 2 to 3 g/d) for seven days. Ouabain-sensitive 86Rb+ influx into the re...

journal_title：American journal of hypertension

authors： Ashida T,Kuramochi M,Kojima S,Yoshimi H,Kawano Y,Kimura G,Abe H,Imanishi M,Yoshida K,Kawamura M

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:The mechanisms by which heme oxygenase (HO) improves glucose metabolism in essential hypertension are not completely understood. Because dysfunctional insulin signaling is associated with elevated inflammation and high cholesterol and triglycerides, we investigated the effects of HO on the proinflammatory ma...

journal_title：American journal of hypertension

authors： Ndisang JF,Mishra M

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Masked hypertension (MHT), defined as normal blood pressure (BP) at office associated with high BP at home, has been shown to be associated with an increased risk of vascular events. However, MHT is poorly known in the elderly, although this age segment is at high risk of hypertension-related vascular events...

journal_title：American journal of hypertension

authors： Cacciolati C,Hanon O,Alpérovitch A,Dufouil C,Tzourio C

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To determine the effects of orthostatic hypotension (OH) measurement timing on its associations with dizziness, falls, fractures, cardiovascular disease (CVD), and mortality. METHODS:We analyzed OH measurements from the Action to Control Cardiovascular Risk in Diabetes BP trial, which evaluated two blood pre...

journal_title：American journal of hypertension

authors： Juraschek SP,Lipsitz LA,Beach JL,Mukamal KJ

更新日期：2019-06-11 00:00:00

abstract：:High levels of plasma homocyst(e)ine (H[e]) are associated with increased vascular risk. Treatment is being contemplated, but the level at which patients should be treated is not known. We compared the response of carotid plaque to vitamin therapy in patients with H(e) above and below 14 micromol/L, a level commonly r...

journal_title：American journal of hypertension

authors： Hackam DG,Peterson JC,Spence JD

更新日期：2000-01-01 00:00:00

abstract：:The hypothesis that elevated Ca2+ intake lowers blood pressure in the spontaneously hypertensive rat (SHR) by altering intrinsic contractile properties of vascular smooth muscle was tested. The effect of 0.5, 1, and 2% Ca2+ in the diet on systolic blood pressure, serum-ionized Ca2+, and contractile properties of mesen...

journal_title：American journal of hypertension

authors： Bukoski RD,Xue H,McCarron DA

更新日期：1989-06-01 00:00:00

abstract：:Safety in the drug treatment of hypertension can only be seen in relation to efficacy, which has now come to mean not just blood pressure (BP) reduction but improvements in hard end points including mortality. Information on safety can come from a variety of sources, in an ascending hierarchy, which is as follows: cas...

journal_title：American journal of hypertension

authors： Opie LH

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Debate exists about the relationship between hypovitaminosis D and cardiovascular (CVD) risk. METHODS:This study investigated baseline (n=2,271) 25-hydroxyvitamin D (25(OH)D) and baseline and 4 year (n=1,957) CVD risk in a cohort of Finnish middle-aged male smokers. RESULTS:The prevalences of measured hype...

journal_title：American journal of hypertension

authors： Ke L,Graubard BI,Albanes D,Fraser DR,Weinstein SJ,Virtamo J,Brock KE

更新日期：2013-08-01 00:00:00

abstract：:Medical literature that has coalesced during the past two to three decades has identified adequate intake of nutrients from dairy foods as a common factor in the reduction of the disease burden of several common medical conditions. These include obesity, hypertension, type 2 diabetes, osteoporosis, kidney stones, cert...

journal_title：American journal of hypertension

authors： McCarron DA,Heaney RP

更新日期：2004-01-01 00:00:00

abstract：:The current study tested the hypothesis that centrally administered relaxin elevates arterial pressure in conscious rats and that this hypertensive effect is mediated, at least in part, by central or peripheral vasopressin. Injection of human relaxin (0.068 or 0.34 microgram in 200 nL artificial cerebrospinal fluid) i...

journal_title：American journal of hypertension

authors： Yang RH,Bunting S,Wyss JM,Berecek KH,Zhang L,Jin H

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:Normal pregnancy is characterized by a decrease in peripheral resistance and generalized vasodilation resulting in plasma volume expansion, which is associated with intrauterine growth. Stiffness of the arterial system may be a measure of the degree of plasma volume expansion. Pulse wave velocity (PWV), meas...

journal_title：American journal of hypertension

authors： Elvan-Taspinar A,Franx A,Bots ML,Koomans HA,Bruinse HW

更新日期：2005-03-01 00:00:00

abstract：:A significant and positive association between red blood cell sodium lithium countertransport (Na-Li CT) and blood pressure has been found in numerous studies. However, the majority of the studies presented to date are cross-sectional in nature and limited information exists on the longitudinal association between Na-...

journal_title：American journal of hypertension

authors： Trevisan M,Strazzullo P,Cappuccio F,Jossa F,Iacone R,Russo I,Farinaro E

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Insulin inhibits contraction and migration of primary confluent, cultured canine vascular smooth muscle cells (VSMCs) with inducible nitric oxide synthase (iNOS) by stimulating cyclic GMP (cGMP) production. The present study was performed to determine how insulin stimulates guanylate cyclase activity in thes...

journal_title：American journal of hypertension

authors： Kahn AM,Allen JC,Zhang S

更新日期：2002-03-01 00:00:00

abstract：:Apart from the well-known role of hypertension in cerebrovascular disease, visit-to-visit blood pressure (BP) variability is emerging as an independent risk factor for stroke. Although the underlying mechanism is not fully understood, artery remodeling is thought to be closely involved in the relationship between visi...

journal_title：American journal of hypertension

authors： Nagai M,Kario K

更新日期：2013-12-01 00:00:00

abstract：:Hyperinsulinemia and dyslipidemia are known to be associated with essential hypertension but their role in pregnancy-induced hypertension remains unclear. We performed a case-control study comparing cholesterol, insulin, and glucose levels in the early third trimester of pregnancy among 31 women who developed pregnanc...

journal_title：American journal of hypertension

authors： Solomon CG,Carroll JS,Okamura K,Graves SW,Seely EW

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:We reported that insulin modestly stimulates NAD(P)H oxidase activity in cultured rat vascular smooth muscle cells (VSMC) and synergistically stimulates enzyme activity with angiotensin II (Ang II), leading to synergistic stimulation of VSMC migration. The aim of this study was to determine the mechanism of ...

journal_title：American journal of hypertension

authors： Yang M,Kahn AM

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Although several characteristics of aortic function, which are largely determined by age, predict outcomes beyond brachial blood pressure (BP), the extent to which brachial BP control accounts for age-related variations in aortic function is uncertain. We aimed to determine the extent to which brachial BP co...

journal_title：American journal of hypertension

authors： Hodson B,Norton GR,Booysen HL,Sibiya MJ,Raymond A,Maseko MJ,Majane OH,Libhaber E,Sareli P,Woodiwiss AJ

更新日期：2016-05-01 00:00:00

abstract：:Leptin may be a link in the relationship of obesity with hypertension. We evaluated associations of leptin with blood pressure (BP) in 54 normotensive and 114 hypertensive African American individuals. Plasma leptin was higher (P <.03) in hypertensive women than in normotensive women, although body mass index did not ...

journal_title：American journal of hypertension

authors： El-Gharbawy AH,Kotchen JM,Grim CE,Kaldunski M,Hoffmann RG,Pausova Z,Hamet P,Kotchen TA

更新日期：2002-11-01 00:00:00

abstract：:After a brief historic survey, sympathetic-neurogenic contributions to the multifactorial, polygenetically linked etiology of primary (essential) hypertension are outlined towards the background of experimental findings both in various rat models and in human subjects. It is emphasized how at least some variants of bo...

journal_title：American journal of hypertension

authors： Folkow B

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Elastin microfibril interfacer 1 (EMILIN-1) is a negative regulator of the transforming growth factor-beta (TGF-beta) signaling, which is involved in blood pressure (BP) homeostasis. Emilin1 knockout mice display elevated BP. The aim of the present study was to assess the association between the human EMILIN...

journal_title：American journal of hypertension

authors： Shimodaira M,Nakayama T,Sato N,Naganuma T,Yamaguchi M,Aoi N,Sato M,Izumi Y,Soma M,Matsumoto K

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The angiotensin II type 1 receptor A1166C polymorphism has been associated with increased risks of hypertension and myocardial infarction in several small studies. We examined the association between this polymorphism and new-onset hypertension, blood pressure (BP) control, and incident cardiovascular events...

journal_title：American journal of hypertension

authors： Hindorff LA,Heckbert SR,Tracy R,Tang Z,Psaty BM,Edwards KL,Siscovick DS,Kronmal RA,Nazar-Stewart V

更新日期：2002-12-01 00:00:00