Pressor and bradycardic effects of centrally administered relaxin in conscious rats.

abstract：BACKGROUND:Hypertension is the most prevalent chronic disease worldwide. Lifestyle behaviors for its prevention and control are recommended within worldwide guidelines. Nevertheless, their combined relationship with blood pressure (BP) level, particularly in the general population, would need more investigations. Our a...

journal_title：American journal of hypertension

authors： Lelong H,Galan P,Kesse-Guyot E,Fezeu L,Hercberg S,Blacher J

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The genetic component related to blood pressure (BP) changes during pregnancy is still not elucidated. Thus, the aim of the study was to evaluate the association between leptin and leptin receptor polymorphisms and systolic (SBP) and diastolic BP (DBP) variation during pregnancy and the postpartum period. M...

journal_title：American journal of hypertension

authors： Farias DR,Franco-Sena AB,Rebelo F,Salles GF,Struchiner CJ,Martins MC,Kac G

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Physical activity (PA) has been associated with decreased left ventricular (LV) hypertrophy in previous studies. However, little is known about the relationship between PA and LV structure and factors which influence this relationship among African Americans. METHODS:We evaluated 1,300 African Americans wit...

journal_title：American journal of hypertension

authors： Kamimura D,Loprinzi PD,Wang W,Suzuki T,Butler KR,Mosley TH,Hall ME

更新日期：2017-06-01 00:00:00

abstract：:Managing hypertension is a complex undertaking, where even the definition of the disorder is subject to discussion. Recently, there has been controversy concerning the most appropriate measure to determine health risks associated with hypertension. In the past, diastolic blood pressure (DBP) was the prime measure for ...

journal_title：American journal of hypertension

authors： Cushman WC

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Subjects with renovascular hypertension (RVH) often manifest with metabolic syndrome (MetS) as well. Coexisting MetS and hypertension increases cardiovascular morbidity and mortality, but the mechanisms underlying cardiac injury remain unknown. We hypothesized that superimposition of MetS induces myocardial ...

journal_title：American journal of hypertension

authors： Aghajani Nargesi A,Farah MC,Zhu XY,Zhang L,Tang H,Jordan KL,Saadiq IM,Lerman A,Lerman LO,Eirin A

更新日期：2020-12-05 00:00:00

abstract：:In a population of 887 men and 1159 women aged 40 to 89 years in southern California, age adjusted systolic and diastolic blood pressures correlated significantly with sodium/potassium ratios estimated from casual urine samples. The relationship was apparent over the whole range of blood pressures and urinary electrol...

journal_title：American journal of hypertension

authors： Khaw KT,Barrett-Connor E

更新日期：1990-06-01 00:00:00

abstract：:In a randomized double-blind, placebo-controlled, crossover study of isradipine (5 mg twice daily), effects on peripheral hemodynamic reflex responses were studied in nine patients (mean age 48 years) at baseline and after six weeks of active treatment. Assessments included vital signs, resting blood flow in the calf ...

journal_title：American journal of hypertension

authors： Duprez D,De Backer T,De Pue N,Hermans L,De Buyzere M,Clement DL

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:The polymorphism of several candidate genes has been studied in relation to essential hypertension and cardiovascular complications. Target organ damage in essential hypertension is a complex disorder influenced by multiple genetic and environmental factors. The possible contribution of endothelin gene varia...

journal_title：American journal of hypertension

authors： Lajemi M,Gautier S,Poirier O,Baguet JP,Mimran A,Gosse P,Hanon O,Labat C,Cambien F,Benetos A

更新日期：2001-08-01 00:00:00

abstract：:To assess whether aerobic exercise training is an effective and an alternative method to control blood pressure (BP) in hypertension, 32 uncomplicated, never treated patients suffering from mild-to-moderate essential arterial hypertension (EAH) were included in an aerobic exercise training program using a regular stan...

journal_title：American journal of hypertension

authors： Nami R,Mondillo S,Agricola E,Lenti S,Ferro G,Nami N,Tarantino M,Glauco G,Spanò E,Gennari C

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Left ventricular hypertrophy (LVH) is an independent risk factor for cardiovascular morbidity in hypertension. Current evidence suggests a contribution to LVH of plasma aldosterone levels that are inappropriately elevated for the salt status. The aim of this study was to investigate whether inappropriate mod...

journal_title：American journal of hypertension

authors： Catena C,Verheyen ND,Url-Michitsch M,Kraigher-Krainer E,Colussi G,Pilz S,Tomaschitz A,Pieske B,Sechi LA

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:In the United States, roughly one-third of adults have hypertension; another third have prehypertension. The prevalence of hypertension in deaf American Sign Language (ASL) users is unknown. We address this gap through a descriptive study for the prevalence of hypertension in the American Deaf community and ...

journal_title：American journal of hypertension

authors： Simons AN,Moreland CJ,Kushalnagar P

更新日期：2018-10-15 00:00:00

abstract：:The goal of this study was to investigate the activity of the Na+/H+ exchanger in erythrocytes of patients with essential hypertension and its relation with urinary Na+ excretion. The study was performed in cells from 27 untreated hypertensive patients and 30 normotensive controls with similar age and sex distribution...

journal_title：American journal of hypertension

authors： Díez J,Alonso A,Garciandía A,López R,Gómez-Alamillo C,Arrázola A,Fortuño A

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:The W allele of the G460W polymorphism in the adducin-1 gene has been occasionally associated with increased blood pressure (BP). The aim of this study was to test whether the G460W variant is associated with BP levels and BP progression rate and whether G460W associations with BP are affected by sex, body m...

journal_title：American journal of hypertension

authors： Fava C,Montagnana M,Almgren P,Rosberg L,Guidi GC,Berglund G,Melander O

更新日期：2007-09-01 00:00:00

abstract：:Hypertensive renal injury is a major identifiable cause of end-stage renal disease in African-Americans. A complex nexus of sociologic, biologic, environmental, and sociocultural variables are involved in mediating this risk and interrelate with dietary salt consumption and salt sensitivity. It is likely that dietary ...

journal_title：American journal of hypertension

authors： Weir MR

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:It is not known whether strict control of blood pressure (BP) in mild post-transplant hypertension gives any benefit. Our primary objective was to test the antihypertensive effects of lisinopril added to standard therapy on ambulatory BP (ABP) of post-transplant patients. The secondary objective was to monit...

journal_title：American journal of hypertension

authors： Opie LH,Haus M,Commerford PJ,Levetan B,Moore K,Brink J

更新日期：2002-10-01 00:00:00

abstract：:Fenoldopam (Corlopam), a new dopaminergic agent in clinical development by SmithKline Beecham Pharmaceuticals, is a dopamine-1 (DA1) agonist at post-synaptic dopamine receptors. Preclinical and clinical studies have demonstrated that it is a potent renal vasodilator as well as a peripheral vasodilator. In both normal ...

journal_title：American journal of hypertension

authors： Holcslaw TL,Beck TR

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:There is growing evidence that residential environment is associated with hypertension. Recently, interest has also turned toward examining the possible influence of remoteness on hypertension. The aim of this study is to explore the effect of remoteness, the shortest path between the subject location and th...

journal_title：American journal of hypertension

authors： Hamano T,Kimura Y,Takeda M,Yamasaki M,Nabika T,Shiwaku K

更新日期：2012-07-01 00:00:00

abstract：:The Captopril Prevention Project (CAPPP) is an ongoing prospective intervention study in 10,800 hypertensive patients in Sweden and Finland. Patients are randomized to treatment with either conventional antihypertensive therapy, ie, diuretics or beta-blockers, or the angiotensin-converting enzyme inhibitor captopril. ...

journal_title：American journal of hypertension

authors： Hansson L

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Subjects with hypertension are frequently obese or insulin resistant, both conditions in which hyperuricemia is common. Obese and insulin-resistant subjects are also known to have blood pressure that is more sensitive to changes in dietary sodium intake. Whether hyperuricemia is a resulting consequence, mode...

journal_title：American journal of hypertension

authors： Todd AS,Walker RJ,MacGinley RJ,Kelly J,Merriman TR,Major TJ,Johnson RJ

更新日期：2017-11-06 00:00:00

abstract：:The different modes of antihypertensive action of beta-adrenoceptor blocking drugs are reviewed with a special emphasis on renal mechanisms of action. Beta-adrenoceptors occur in the kidney at the level of the juxtaglomerular and tubular cells. Direct intrarenal effects of beta-blockers include the decrease in renin r...

journal_title：American journal of hypertension

authors： Struyker-Boudier HA,Smits JF

更新日期：1989-11-01 00:00:00

abstract：:Arterial hypertension is a powerful risk factor for cardiovascular disease, but the ability to use blood pressure measurements to predict complications in individual patients or small groups is limited. One possible approach to identifying hypertensive patients at high risk is based on the observation that the presenc...

journal_title：American journal of hypertension

authors： Devereux RB

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Vitamin D is involved in blood pressure (BP) regulation. Genetic variations may influence the effect of vitamin D on BP, but data from epidemiologic studies remain inconsistent. METHODS:We conducted a comprehensive genetic association study in the Women's Genome Health Study (WGHS) with genome-wide genotype...

journal_title：American journal of hypertension

authors： Wang L,Chu A,Buring JE,Ridker PM,Chasman DI,Sesso HD

更新日期：2014-11-01 00:00:00

abstract：:Migration of monocytes into the subendothelial space of the aorta has been considered to be an important event in the development of atherosclerosis. Because hypertension is commonly associated with atherosclerosis, we studied the effect of applied pressure on the migration of monocytes. Direct applied pressure increa...

journal_title：American journal of hypertension

authors： Singhal PC,Sagar P,Gupta S,Arya M,Gupta M,Prasad A,Loona R,Sharma P,Mattana J

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:Sustained hypotension after an acute dynamic exercise bout is due primarily to peripheral vasodilation. We tested the hypothesis that adenosine-mediated vasodilation contributes to hypotension after exercise, by determining the effect of blocking its actions with caffeine. METHODS:Fourteen healthy middle-ag...

journal_title：American journal of hypertension

authors： Notarius CF,Morris BL,Floras JS

更新日期：2006-02-01 00:00:00

abstract：:Decreased urinary kallikrein excretion has been shown to be related to hypertension. Kallikrein levels also have been shown to be determined primarily by genes, with 51% of the total variance being due to a single gene. However, there exists strong spouse-spouse correlation, indicating that common environment plays a ...

journal_title：American journal of hypertension

authors： Hunt SC,Wu LL,Slattery ML,Meikle AW,Williams RR

更新日期：1993-03-01 00:00:00

abstract：:We studied the role of the sympathetic nervous system and the renin angiotensin system for pressure induced left ventricular hypertrophy (LVH) in 135 rats with experimental supravalvular aortic stenosis (AS). We induced this condition by a silver clip on the ascending aorta, when body weight (BW) was 90 to 100 g. Symp...

journal_title：American journal of hypertension

authors： Kromer EP,Elsner D,Riegger GA

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Inadequately treated hypertension (HTN) leads to considerable morbidity and mortality. Despite many treatment options, blood pressure (BP) control is suboptimal. Missed opportunities due to the growing complexity of primary care office visits contribute. Electronic health records (EHRs) offer best practice a...

journal_title：American journal of hypertension

authors： Swedlund M,Norton D,Birstler J,Chen G,Cruz L,Hanrahan L

更新日期：2019-01-01 00:00:00

abstract：:In vivo studies suggest that 17 beta-estradiol (beta E) may regulate vascular tone. Results of recent studies suggest that beta E exerts rapid effects on intracellular calcium, possibly via cell surface receptors, distinct from conventional nuclear receptors for steroids. The present study was designed to determine wh...

journal_title：American journal of hypertension

authors： Ravi J,Mantzoros CS,Prabhu AS,Ram JL,Sowers JR

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Carotid-femoral pulse-wave velocity (PWV) provides a comprehensive noninvasive indication of arterial stiffness, and is now established as a strong marker of cardiovascular disease (CVD). The correlation between peripheral blood pressure (BP) and PWV and their respective influences on mortality have been poo...

journal_title：American journal of hypertension

authors： Miljkovic D,Perret-Guillaume C,Alla F,Salvi P,Erpelding ML,Benetos A

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Myocardial infarction (MI) is commonly associated with cardiac hypertrophy, reduced Ca²(+) uptake into the sarcoplasmic reticulum (SR) and impaired myocardial relaxation. Treatment to prevent MI-associated complications is currently lacking. The purpose of the present study was to investigate the remodeling ...

journal_title：American journal of hypertension

authors： Costa DG,da Silva JS,Kümmerle AE,Sudo RT,Landgraf SS,Caruso-Neves C,Fraga CA,de Lacerda Barreiro EJ,Zapata-Sudo G

更新日期：2010-11-01 00:00:00