The association of nephrolithiasis with hypertension and obesity: a review.

Abstract:

:Kidney stones affect hypertensive patients disproportionately compared to normotensive individuals. On the other hand, some prospective data suggest that a history of nephrolithiasis was associated with a greater tendency to develop hypertension. Newer epidemiologic data also link obesity and diabetes, features of the metabolic syndrome, with nephrolithiasis. In this review, the association of hypertension, diabetes, and obesity with nephrolithiasis is reviewed, and possible pathogenic mechanisms are discussed. Patients with hypertension may have abnormalities of renal calcium metabolism, but data confirming this hypothesis are inconsistent. Higher body mass index and insulin resistance (i.e., the metabolic syndrome) may be etiologic in uric acid nephrolithiasis as increasing body weight is associated with decreasing urinary pH. The possibility that common pathophysiologic mechanisms underly these diseases is intriguing, and if better understood, could potentially lead to better therapies for stone prevention. Both hypertension and stones might be addressed through lifestyle modification to prevent weight gain. Adoption of a lower sodium diet with increased fruits and vegetables and low-fat dairy products, (for example, the dietary approaches to stop hypertension(DASH) diet), may be useful to prevent both stones and hypertension. In those patients in whom dietary modification and weight loss are ineffective, thiazide diuretics are likely to improve blood pressure control and decrease calciuria.

journal_name

Am J Hypertens

authors

Obligado SH,Goldfarb DS

doi

10.1038/ajh.2007.62

subject

Has Abstract

pub_date

2008-03-01 00:00:00

pages

257-64

issue

3

eissn

0895-7061

issn

1941-7225

pii

ajh200762

journal_volume

21

pub_type

杂志文章,评审
  • Association of longitudinal changes in NT-proBNP with changes in Left Atrial Volume and Function: MESA.

    abstract:BACKGROUND:The mechanism of left atrial (LA) remodeling is poorly understood. The aim of this longitudinal study was to investigate whether changes in NT-proBNP levels relate to alterations of LA structure and function over time in a multi-ethnic population. METHODS:From the prospective cohort study, the Multi-Ethnic ...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/hpab018

    authors: Varadarajan V,Ambale-Venkatesh B,Hong SY,Habibi M,Ashikaga H,Wu CO,Chen LY,Heckbert SR,Bluemke DA,Lima JAC

    更新日期:2021-01-25 00:00:00

  • Interaction of 1,25-dihydroxyvitamin D and plasma renin activity in high renin essential hypertension.

    abstract::Renin secretion by the kidney is inhibited by an increase in free intracellular calcium concentration. This increase in free intracellular calcium content may be augmented by serum 1,25-dihydroxyvitamin D. In 10 subjects with high renin hypertension, an increase in dietary sodium intake resulted in an increase in urin...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/ajh/3.12.903

    authors: Burgess ED,Hawkins RG,Watanabe M

    更新日期:1990-12-01 00:00:00

  • Comparison of arterial assessments in low and high vascular disease risk groups.

    abstract:BACKGROUND:An increasing number of arterial function assessments are available, including small and large arterial elasticity (SAE/C2, LAE/C1), endothelial function as measured by flow mediated dilation (FMD), carotid intima-medial thickness (IMT), ankle brachial index (ABI), pulse pressure (PP), and pulse wave velocit...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/j.amjhyper.2003.10.009

    authors: Wilson AM,O'Neal D,Nelson CL,Prior DL,Best JD,Jenkins AJ

    更新日期:2004-04-01 00:00:00

  • Left ventricular mass in normotensive subjects. Importance of blood pressure response to activity.

    abstract::Recent works have shown the importance of blood pressure (BP) response to exercise or to daily activity as determinants of hypertensive cardiac hypertrophy. We have tested the relationship between BP and left ventricular (LV) mass in 23 normotensive young adults (mean age 25 +/- 5) with normotensive parents. Blood pre...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/2.2.78

    authors: Gosse P,Desrumeau GC,Roudaut R,Broustet JP,Dallocchio M

    更新日期:1989-02-01 00:00:00

  • Factors Associated With Treatment and Control of Hypertension in a Healthy Elderly Population Free of Cardiovascular Disease: A Cross-sectional Study.

    abstract:BACKGROUND:Despite readily available treatments, control of blood pressure (BP) with population aging remains suboptimal. Further, there are gaps in the understanding of the management of high BP in the aged. We explored antihypertensive treatment and control among elderly hypertensive participants free from overt card...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,多中心研究

    doi:10.1093/ajh/hpz192

    authors: Chowdhury EK,Nelson MR,Ernst ME,Margolis KL,Beilin LJ,Johnston CI,Woods RL,Murray AM,Wolfe R,Storey E,Shah RC,Lockery JE,Tonkin AM,Newman AB,Williamson JD,Abhayaratna WP,Stocks NP,Fitzgerald SM,Orchard SG,Trevaks RE

    更新日期:2020-04-01 00:00:00

  • Association of increased erythrocyte Na+/H+ exchanger with renal Na+ retention in patients with essential hypertension.

    abstract::The goal of this study was to investigate the activity of the Na+/H+ exchanger in erythrocytes of patients with essential hypertension and its relation with urinary Na+ excretion. The study was performed in cells from 27 untreated hypertensive patients and 30 normotensive controls with similar age and sex distribution...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/0895-7061(94)00172-8

    authors: Díez J,Alonso A,Garciandía A,López R,Gómez-Alamillo C,Arrázola A,Fortuño A

    更新日期:1995-02-01 00:00:00

  • Aortic pulse pressure is associated with carotid IMT in chronic kidney disease: report from Chronic Renal Insufficiency Cohort.

    abstract:BACKGROUND:Patients with chronic kidney disease (CKD) have a disproportionate risk of cardiovascular disease. This study was designed to assess the association between two noninvasive measures of cardiovascular risk, pulse wave analysis (PWA), and carotid intima-media thickness (IMT), in a cohort of CKD patients enroll...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1038/ajh.2009.156

    authors: DeLoach SS,Appel LJ,Chen J,Joffe MM,Gadegbeku CA,Mohler ER 3rd,Parsa A,Perumal K,Rafey MA,Steigerwalt SP,Teal V,Townsend RR,Rosas SE

    更新日期:2009-12-01 00:00:00

  • Control of hypertension in treated children and its association with target organ damage.

    abstract:BACKGROUND:The aim of our study was to investigate the control of hypertension (HT) in treated children using ambulatory blood pressure (BP) monitoring (ABPM). METHODS:We retrospectively reviewed all ABPM studies in our center. Controlled HT was defined as systolic and diastolic BP index (patients' BP divided by the 9...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1038/ajh.2011.218

    authors: Seeman T,Dostálek L,Gilík J

    更新日期:2012-03-01 00:00:00

  • Improvement of insulin sensitivity by a long-acting nifedipine preparation (nifedipine-CR) in patients with essential hypertension.

    abstract:BACKGROUND:Nifedipine has been reported to cause impairment of insulin sensitivity. But recently a controlled-released formulation of nifedipine (nifedipine-GITS) has been reported that it could improve insulin sensitivity. METHODS:We evaluated insulin sensitivity in two groups of essential hypertensive subjects befor...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0895-7061(02)03019-4

    authors: Koyama Y,Kodama K,Suzuki M,Harano Y

    更新日期:2002-11-01 00:00:00

  • Inhibition of oxidative stress and improvement of endothelial function by amlodipine in angiotensin II-infused rats.

    abstract:BACKGROUND:Calcium channel blockers such as amlodipine are effective antihypertensive agents. In this study we investigated the effects of amlodipine on vascular oxidative stress, expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1), and endothelial function in angiotensin (Ang) II-infused ra...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/j.amjhyper.2003.09.007

    authors: Zhou MS,Jaimes EA,Raij L

    更新日期:2004-02-01 00:00:00

  • High dietary salt enhances acute depressor responses to metformin.

    abstract::The antidiabetic drug metformin lowers blood pressure (BP) more in spontaneously hypertensive rats (SHR) compared with Wistar-Kyoto rats (WKY), and the hypotensive effect is enhanced by high dietary salt. To determine whether enhanced hypotension is secondary to greater decreases in sympathetic nerve activity (SNA), w...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/s0895-7061(99)00119-3

    authors: Muntzel MS,Nyeduala B,Barrett S

    更新日期:1999-12-01 00:00:00

  • Comparisons of the effects of different long-acting delivery systems on the pharmacokinetics and pharmacodynamics of diltiazem.

    abstract::The benzothiazepine calcium channel antagonist diltiazem is a short-acting drug. To achieve effective 24-h blood pressure control with once-daily dosing, it relies on various extended drug-delivery systems that have grown in importance as a result of the recent reports relating the use of short-acting calcium channel ...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0895-7061(99)00097-7

    authors: Smith DH,Neutel JM,Weber MA

    更新日期:1999-10-01 00:00:00

  • Blood pressure, brain structure, and cognition: opposite associations in men and women.

    abstract:BACKGROUND:Research on associations between blood pressure, brain structure, and cognitive function has produced somewhat inconsistent results. In part, this may be due to differences in age ranges studied and because of sex differences in physiology and/or exposure to risk factors, which may lead to different time cou...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/hpu120

    authors: Cherbuin N,Mortby ME,Janke AL,Sachdev PS,Abhayaratna WP,Anstey KJ

    更新日期:2015-02-01 00:00:00

  • The Influence of Sodium and Potassium Intake and Insulin Resistance on Blood Pressure in Normotensive Individuals Is More Evident in Women.

    abstract:BACKGROUND:Considering sex differences, salt sensitivity, and insulin resistance (IR), the effect of sodium restriction and increased potassium intake on blood pressure remains unclear in normotensive Asian individuals, compared to that in hypertensive patients. METHODS:To assess the influence of sodium and potassium ...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/hpy041

    authors: Murao S,Takata Y,Yasuda M,Osawa H,Kohi F

    更新日期:2018-07-16 00:00:00

  • Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-day carvedilol treatment.

    abstract:BACKGROUND:The aim of this study was to clarify the response of endothelial connexins to hypertension and antihypertensive drugs. METHODS:Rats remained normotensive (group 1, N = 10) or were made hypertensive using N(omega)-nitro-L-arginine methyl ester (L-NAME) (groups 2 to 4, N = 10/group). Seven weeks later groups ...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/j.amjhyper.2005.08.020

    authors: Yeh HI,Lee PY,Su CH,Tian TY,Ko YS,Tsai CH

    更新日期:2006-02-01 00:00:00

  • A longitudinal study of urinary creatinine and creatinine clearance in normal subjects. Race, sex, and age differences.

    abstract::The purpose of this study was to examine the variability of 24-hour urinary and serum creatinine levels and creatinine clearance in normal subjects and to develop nomograms for assessing the adequacy of 24-hour urine collections. The data were from a longitudinal research program examining biochemical, hormonal, and h...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/1.2.124

    authors: James GD,Sealey JE,Alderman M,Ljungman S,Mueller FB,Pecker MS,Laragh JH

    更新日期:1988-04-01 00:00:00

  • Clofibrate acutely reverses saline-induced endothelial dysfunction: role of calcium-activated potassium channels.

    abstract:BACKGROUND:Endothelium-dependent vascular relaxation is impaired in various disease states including hypertension. METHODS:We investigated whether a single bolus dose of clofibrate could rapidly reverse saline-induced endothelial dysfunction, in vivo, in salt-loaded Sprague-Dawley (S-D) rats. S-D rats, 5 weeks of age,...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/j.amjhyper.2006.04.005

    authors: Sankaralingam S,Desai KM,Wilson TW

    更新日期:2006-11-01 00:00:00

  • Association between levels of blood pressure and measures of subclinical disease multi-ethnic study of atherosclerosis.

    abstract:BACKGROUND:High blood pressure (BP) is associated with the presence and severity of subclinical disease. Less is known about associations between normal levels of BP and various measures of subclinical disease. METHODS:The Multi-Ethnic Study of Atherosclerosis (MESA) enrolled 6814 participants free of clinical cardiov...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/j.amjhyper.2006.04.002

    authors: Psaty BM,Arnold AM,Olson J,Saad MF,Shea S,Post W,Burke GL

    更新日期:2006-11-01 00:00:00

  • Blood pressure and the risk of stroke, cardiovascular disease, and all-cause mortality among Japanese: the JPHC Study.

    abstract:BACKGROUND:Little is known about the influence of blood pressure (BP) on cardiovascular disease (CVD) outcomes among Asian populations. METHODS:We examined population attributable fractions (PAFs) and hazard ratios (HRs) associated with BP in relation to stroke and coronary heart disease (CHD) incident and mortality w...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1038/ajh.2008.356

    authors: Ikeda A,Iso H,Yamagishi K,Inoue M,Tsugane S

    更新日期:2009-03-01 00:00:00

  • Effect of dietary sodium on the Na-K ATPase inhibitor in patients with essential hypertension.

    abstract::To study the circulating humoral factor modifying transmembrane sodium transport, plasma was obtained from 12 patients with essential hypertension (EH) fed a high sodium diet (NaCl 15 to 17 g/d) for seven days and thereafter a low sodium diet (NaCl 2 to 3 g/d) for seven days. Ouabain-sensitive 86Rb+ influx into the re...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/2.7.560

    authors: Ashida T,Kuramochi M,Kojima S,Yoshimi H,Kawano Y,Kimura G,Abe H,Imanishi M,Yoshida K,Kawamura M

    更新日期:1989-07-01 00:00:00

  • Improved cardiovascular risk stratification by a simple ECG index in hypertension.

    abstract:BACKGROUND:We determined the prognostic value of the Cornell/strain [C/S] index, a simple electrocardiographic (ECG) index for left ventricular hypertrophy (LVH) defined by the presence of either a classic strain pattern or a Cornell voltage (sum of R in aVL + S in V(3)) >2.0 mV in women or 2.4 mV in men, or both. MET...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0895-7061(03)00912-9

    authors: Verdecchia P,Angeli F,Reboldi G,Carluccio E,Benemio G,Gattobigio R,Borgioni C,Bentivoglio M,Porcellati C,Ambrosio G

    更新日期:2003-08-01 00:00:00

  • The Metabolic Syndrome Does Not Affect Development of Collateral Circulation in the Poststenotic Swine Kidney.

    abstract:BACKGROUND:The collateral circulation is important in maintenance of blood supply to the ischemic kidney distal to renal artery stenosis (RAS). Obesity metabolic syndrome (MetS) preserves renal blood flow (RBF) in the stenotic kidney, but whether this is related to an increase of collateral vessel growth is unknown. We...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/hpy127

    authors: Zhang X,Kim SR,Ferguson CM,Ebrahimi B,Hedayat AF,Lerman A,Lerman LO

    更新日期:2018-11-13 00:00:00

  • Patterns of insulin secretion and responsiveness in Wistar-Kyoto and spontaneously hypertensive rats.

    abstract::An intravenous glucose tolerance test (IVGTT) was performed on 16 spontaneously hypertensive rats (SHR) and 15 Wistar-Kyoto rats (WKY) by challenging them with an intravenous glucose load of 0.125 g/100 g body weight. Serum glucose and insulin were measured at 0, 15, 30, 60, 120, and 240 min. In a second experiment, o...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/4.8.661

    authors: Gaboury CL,Karanja N,Holcomb SR,Torok J,McCarron DA

    更新日期:1991-08-01 00:00:00

  • Association of Maternal Plasma Folate and Cardiometabolic Risk Factors in Pregnancy with Elevated Blood Pressure of Offspring in Childhood.

    abstract:BACKGROUND:The prevalence of childhood elevated blood pressure (BP) has increased in the United States, particularly among African Americans. The influence of maternal plasma folate levels, alone or in combination with maternal cardiometabolic risk factors (hypertensive disorders, diabetes, and prepregnancy obesity), o...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/hpx003

    authors: Wang H,Mueller NT,Li J,Sun N,Huo Y,Ren F,Wang X

    更新日期:2017-05-01 00:00:00

  • Renal tissue kallikrein in newborn and young SHR.

    abstract::Since young SHR excrete less urinary kallikrein than WKY, active and total kallikrein (A and T Kall, respectively) was measured (amidolytic assay) in the renal cortex of both strains. Neither at birth nor at age 4 weeks did renal T Kall differ between SHR and WKY. Renal A Kall was significantly lower in newborn SHR an...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/1.3.53s

    authors: Ader JL,Tran-Van T,Praddaude F

    更新日期:1988-07-01 00:00:00

  • Clinical experience with the angiotensin II receptor antagonist losartan. A preliminary report.

    abstract::The nonpeptide angiotensin II (AII)-receptor antagonist losartan is a selective blocker of the pressor effects of AII. It is now being evaluated as an anti-hypertensive drug in multicenter clinical trials in the United States and other countries. Preliminary inpatient studies have shown that after 5 days of treatment,...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1093/ajh/5.12.247s

    authors: Weber MA

    更新日期:1992-12-01 00:00:00

  • Hemodynamics of seasonal adaptation.

    abstract::To investigate the possibility that seasonal adaptation requires significant hemodynamic changes, 5 normotensive and 21 mildly hypertensive subjects were followed through 4 seasons for changes in systemic hemodynamics and sympathetic nervous activity. In the upright position wintertime blood pressures increased by 3% ...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/3.5.405

    authors: Izzo JL Jr,Larrabee PS,Sander E,Lillis LM

    更新日期:1990-05-01 00:00:00

  • Angiotensin II regulates cytochrome P-450 steroid hydroxylase enzyme expression in human adrenal glomerulosa cells.

    abstract::We have examined the regulation of cytochrome P-450 side chain cleavage enzyme (P-450SCC) and P-45011 beta (18) hydroxylase (P-450(11) beta) enzyme expression by angiotensin II (AII), the major regulator of aldosterone biosynthesis, in cultured human adrenal glomerulosa cells. We also examined the effect of lipoxygena...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1093/ajh/5.11.800

    authors: Natarajan R,Yang H,Hall PF,Nadler J

    更新日期:1992-11-01 00:00:00

  • Blood pressure early in diabetes depends on a balance between glomerular filtration rate and the renin-angiotensin system.

    abstract::Onset of diabetes increases plasma renin activity (PRA) and glomerular filtration rate (GFR), but blood pressure (BP) is normal. In this study, a 70% surgical reduction in kidney mass (RK) was used to decrease baseline GFR and to prevent hyperfiltration during diabetes, and angiotensin converting enzyme inhibitors (AC...

    journal_title:American journal of hypertension

    pub_type: 杂志文章

    doi:10.1016/j.amjhyper.2006.05.012

    authors: Rojas M,Bell TD,Sturgis LC,Springfield V,Janardhanan R,Fleming C,Brands MW

    更新日期:2006-12-01 00:00:00

  • Diuretics for Hypertension: A Review and Update.

    abstract::This review and update focuses on the clinical features of hydrochlorothiazide (HCTZ), the thiazide-like agents chlorthalidone (CTDN) and indapamide (INDAP), potassium-sparing ENaC inhibitors and aldosterone receptor antagonists, and loop diuretics. Diuretics are the second most commonly prescribed class of antihypert...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1093/ajh/hpw030

    authors: Roush GC,Sica DA

    更新日期:2016-10-01 00:00:00