Blood pressure, brain structure, and cognition: opposite associations in men and women.

abstract：:This study was designed to evaluate the impact of the protocol-driven antihypertensive therapy on outcomes guided by the Joint National Committee (JNC) on Detection, Evaluation, and Treatment of high blood pressure. In a systematic hypertension control program for union employees conducted in New York City, untreated ...

journal_title：American journal of hypertension

authors： Alderman MH,Madhavan S,Cohen H

更新日期：1996-05-01 00:00:00

abstract：:The association between obesity and hypertension is well recognized. However, the exact mechanisms whereby obesity causes hypertension are complex and multifactorial. The current article summarizes some of the known mechanisms responsible for obesity hypertension. ...

journal_title：American journal of hypertension

authors： Rocchini AP

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:This study examines the interrelationship between gestational weight gain, pre-pregnancy body mass index (BMI), race/ethnicity, and their association with hypertensive disorders during pregnancy (HDP). METHODS:Data from the 2004-2011 national Pregnancy Risk Assessment Monitoring System (PRAMS) were analyzed...

journal_title：American journal of hypertension

authors： Masho SW,Urban P,Cha S,Ramus R

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The efficacy and safety of angiotensin receptor blockers (ARBs) in the older population is unclear. OBJECTIVES:To determine the efficacy and safety of ARBs in older patients. METHODS:Randomized trials that compared ARBs to control and reported clinical outcomes in patients with a mean age of 65 years or ol...

journal_title：American journal of hypertension

authors： Elgendy IY,Huo T,Chik V,Pepine CJ,Bavry AA

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:The independent prognostic value of daytime and night-time blood pressure (BP) variability estimated by noninvasive 24-h BP monitoring is unclear. METHODS:We followed 2649 initially untreated subjects with essential hypertension for up to 16 years (mean, 6). Variability of BP was estimated by the standard d...

journal_title：American journal of hypertension

authors： Verdecchia P,Angeli F,Gattobigio R,Rapicetta C,Reboldi G

更新日期：2007-02-01 00:00:00

abstract：AIMS:Several studies have indicated that low physical activity is associated with increased risk of cardiovascular disease (CVD) and all-cause mortality among patients with diabetes. The association between physical activity and subclinical cardiovascular changes preceding clinical events remains to be elucidated. We i...

journal_title：American journal of hypertension

authors： Funck KL,Laugesen E,Høyem P,Fleischer J,Cichosz SL,Christiansen JS,Hansen TK,Poulsen PL

更新日期：2016-07-01 00:00:00

abstract：:It is premature to state that ambulatory blood pressure (ABP) values below a given level should be considered normal, and those above it abnormal, in terms of prognostic implications on cardiovascular (CV) morbidity. We do not know whether CV morbidity in hypertensive subjects with apparently normal ABP (white coat hy...

journal_title：American journal of hypertension

authors： Verdecchia P,Porcellati C

更新日期：1993-06-01 00:00:00

abstract：:This article examines the results of the Joint National Committee's Fifth Report on the treatment of hypertension (JNC-V), especially regarding the economic arguments put forth therein. Economics are a poor basis for treatment decisions, as the cheapest therapies may not be the best for any given patient. Broad treatm...

journal_title：American journal of hypertension

authors： Ménard J

更新日期：1994-10-01 00:00:00

abstract：:Angiotensin II (Ang II) and transforming growth factor-beta (TGF-beta) modulate cell growth and metabolism. Our objective was to evaluate the effect of Ang II on the characteristics and expression of TGF-beta receptors on vascular smooth muscle cells (VSMC) from Wistar-Kyoto rats. The addition of TGF-beta1 elicited a ...

journal_title：American journal of hypertension

authors： Fukuda N,Hu WY,Kubo A,Kishioka H,Satoh C,Soma M,Izumi Y,Kanmatsuse K

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:The X-linked angiotensin II type-2 receptor (AT2R) gene 1675G/A polymorphism is located in the short intron 1 of the AT2R gene within a sequence motif conforming to a splice branch site. AT2R is expressed in the human retina, but no previous study examined the association between retinal microvascular phenot...

journal_title：American journal of hypertension

authors： Liu YP,Kuznetsova T,Thijs L,Jin Y,Schmitz B,Brand SM,Brand E,Manunta P,Bianchi G,Struijker-Boudier H,Staessen JA

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Recently, the central augmentation index (AIx) has been reported to show a nonlinear correlation with age. We investigated whether the AIx of the central artery changes with the progression of atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits. METHODS:We simultaneously recorded pre...

journal_title：American journal of hypertension

authors： Katsuda S,Miyake M,Kobayashi D,Hazama A,Kusanagi M,Takazawa K

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:About one-half of all hypertensive adults do not have their blood pressure controlled. They are often prescribed medications that conform to national guidelines but they continue to have elevated blood pressure. This public health problem might be improved by applying plasma renin guided therapy. RESULTS:A ...

journal_title：American journal of hypertension

authors： Furberg CD,Sealey JE,Blumenfeld JD

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:The question of whether reduced sodium intake is effective as a health prophylaxis initiative is unsolved. The purpose was to estimate the effects of low-sodium vs. high-sodium intake on blood pressure (BP), renin, aldosterone, catecholamines, and lipids. METHODS:Studies randomizing persons to low-sodium an...

journal_title：American journal of hypertension

authors： Graudal NA,Hubeck-Graudal T,Jürgens G

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:We determined the prognostic value of the Cornell/strain [C/S] index, a simple electrocardiographic (ECG) index for left ventricular hypertrophy (LVH) defined by the presence of either a classic strain pattern or a Cornell voltage (sum of R in aVL + S in V(3)) >2.0 mV in women or 2.4 mV in men, or both. MET...

journal_title：American journal of hypertension

authors： Verdecchia P,Angeli F,Reboldi G,Carluccio E,Benemio G,Gattobigio R,Borgioni C,Bentivoglio M,Porcellati C,Ambrosio G

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to clarify the response of endothelial connexins to hypertension and antihypertensive drugs. METHODS:Rats remained normotensive (group 1, N = 10) or were made hypertensive using N(omega)-nitro-L-arginine methyl ester (L-NAME) (groups 2 to 4, N = 10/group). Seven weeks later groups ...

journal_title：American journal of hypertension

authors： Yeh HI,Lee PY,Su CH,Tian TY,Ko YS,Tsai CH

更新日期：2006-02-01 00:00:00

abstract：:To investigate the possibility that seasonal adaptation requires significant hemodynamic changes, 5 normotensive and 21 mildly hypertensive subjects were followed through 4 seasons for changes in systemic hemodynamics and sympathetic nervous activity. In the upright position wintertime blood pressures increased by 3% ...

journal_title：American journal of hypertension

authors： Izzo JL Jr,Larrabee PS,Sander E,Lillis LM

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Beetroot has attracted much attention because of its blood pressure-lowering properties. Although beetroot contains various nutritional compounds, including inorganic nitrate, some of their physiological properties are not fully understood. In this study, we examined whether betanin, a beetroot component, ha...

journal_title：American journal of hypertension

authors： Tawa M,Masuoka T,Yamashita Y,Nakano K,Ishibashi T

更新日期：2020-04-01 00:00:00

abstract：:Left ventricular hypertrophy in patients with hypertension is an important condition. It is associated with significant mortality and carries increased risk for developing nonfatal cardiovascular complications, including coronary heart disease. The pathogenesis of left ventricular hypertrophy is linked to activation o...

journal_title：American journal of hypertension

authors： Dahlöf B

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:The renal resistive index (RI) measured using Doppler ultrasonography has been used as a diagnostic tool in the daily work-up of kidney diseases. A better understanding of its relationship with preclinical organ damage may help in determining overall cardiovascular risk in hypertensive patients. METHODS:We ...

journal_title：American journal of hypertension

authors： Doi Y,Iwashima Y,Yoshihara F,Kamide K,Takata H,Fujii T,Kubota Y,Nakamura S,Horio T,Kawano Y

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:We reported that insulin modestly stimulates NAD(P)H oxidase activity in cultured rat vascular smooth muscle cells (VSMC) and synergistically stimulates enzyme activity with angiotensin II (Ang II), leading to synergistic stimulation of VSMC migration. The aim of this study was to determine the mechanism of ...

journal_title：American journal of hypertension

authors： Yang M,Kahn AM

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Aim of this study was to evaluate the effect of the telmisartan-amlodipine combination at different doses on urinary albumin excretion rate (UAER) in hypertensive diabetic patients with microalbuminuria. METHODS:After a 2-week placebo period, 300 hypertensive patients with type 2 diabetes and microalbuminur...

journal_title：American journal of hypertension

authors： Fogari R,Derosa G,Zoppi A,Preti P,Lazzari P,Destro M,Fogari E,Rinaldi A,Mugellini A

更新日期：2007-04-01 00:00:00

abstract：:We studied the role of the sympathetic nervous system and the renin angiotensin system for pressure induced left ventricular hypertrophy (LVH) in 135 rats with experimental supravalvular aortic stenosis (AS). We induced this condition by a silver clip on the ascending aorta, when body weight (BW) was 90 to 100 g. Symp...

journal_title：American journal of hypertension

authors： Kromer EP,Elsner D,Riegger GA

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:The polymorphism of several candidate genes has been studied in relation to essential hypertension and cardiovascular complications. Target organ damage in essential hypertension is a complex disorder influenced by multiple genetic and environmental factors. The possible contribution of endothelin gene varia...

journal_title：American journal of hypertension

authors： Lajemi M,Gautier S,Poirier O,Baguet JP,Mimran A,Gosse P,Hanon O,Labat C,Cambien F,Benetos A

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Strong associations between blood pressure (BP) and overweight raise the question whether overweight children (body mass index (BMI) ≥85th percentile) should be included in the normative database. METHODS:Using the LMS (Lamda-Mu-Sigma) method, we developed age-, gender-, and height-adjusted percentile curve...

journal_title：American journal of hypertension

authors： Schwandt P,Scholze JE,Bertsch T,Liepold E,Haas GM

更新日期：2015-05-01 00:00:00

abstract：:Ca2+ efflux from cultured vascular smooth muscle cells (VSMC) consists of two mechanisms: one is dependent on extracellular sodium, mediated by the Na(+)-Ca2+ exchange (Na+o-dependent Ca2+ efflux), and the other is independent of extracellular sodium but is mediated by the Ca(2+)-pump (Na+o-independent Ca2+ efflux). I...

journal_title：American journal of hypertension

authors： Chen S,Roufogalis BD

更新日期：1994-07-01 00:00:00

abstract：:Increased dietary K+ increases plasma [K+] and is linked to or associated with reduced mortality from stroke and reduced blood pressure in humans and animals. We hypothesized that physiologic increases in extracellular [K+] ([K]o) directly inhibit cultured vascular smooth muscle cell (VSMC) proliferation. Studies were...

journal_title：American journal of hypertension

authors： McCabe RD,Young DB

更新日期：1994-04-01 00:00:00

abstract：:Most ambulatory blood pressure monitoring (ABPM) studies have used a mechanical clock as the reference time, but there is no biologic background for assuming that midnight by the mechanical clock is zero hour by the biologic clock. The aim of this study was to determine the biologic zero hour as the zero reference tim...

journal_title：American journal of hypertension

authors： Okutani M,Komori S,Iwasaki H,Mochizuki Y,Kohno I,Mochizuki S,Ishii H,Ijiri H,Tamura K

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:The elevation of left ventricular filling pressure (LVFP) could be an important prognostic factor in patients with hypertension. We hypothesized that noninvasive brachial-ankle pulse wave velocity (baPWV) is associated with increased LVFP in hypertensive patients with LV hypertrophy (LVH). METHODS:We enroll...

journal_title：American journal of hypertension

authors： Park KH,Park WJ,Kim MK,Jung JH,Choi S,Cho JR,Kim HS,Lee N,Cho GY

更新日期：2010-03-01 00:00:00

abstract：:To clarify the function of polymorphonuclear leukocytes (PMN) in spontaneously hypertensive rats (SHR) and the effect of beraprost sodium (BS) on these functions, we examined superoxide anion (O2-) production and adherent activity by PMN, as well as modification of these functions by BS ex vivo and in vitro. In study ...

journal_title：American journal of hypertension

authors： Ohmori M,Kitoh Y,Kawaguchi A,Harada K,Sugimoto K,Fujimura A

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Experimentally induced sleep deprivation can raise blood pressure (BP) and worsen hypertension. We recently reported a significantly higher prevalence of obstructive sleep apnea (OSA) and reduced rapid eye movement (REM) sleep time in drug-resistant hypertensives compared to controlled hypertensives. The obj...

journal_title：American journal of hypertension

authors： Friedman O,Bradley TD,Ruttanaumpawan P,Logan AG

更新日期：2010-02-01 00:00:00