Abstract:
BACKGROUND:Renal angiography (RA) is considered to be the gold standard for the diagnosis of renal artery stenosis (RAS). However, it is invasive and potentially harmful; hence there is a need for an optimal noninvasive test. Magnetic resonance angiography (MRA) is currently accepted as the optimal noninvasive test by many. However, its major drawback is its inability to grade quantitatively the degree of stenosis. In this study, likelihood ratios (LR) were used to compare the diagnostic accuracy of MRA with that of RA. METHODS:To test the hypothesis that semiquantitatively graded MRA would correlate with RA, a retrospective analysis was performed to determine the LR of MRA to diagnose RAS compared with RA. It was believed that LR > or = 10.0 or < or =0.1 might generate conclusive changes from pretest to post-test probabilities. In this study a total of 94 renal arteries from 48 patients were analyzed for RAS by MRA and RA. Stenoses were graded by MRA as mild (<50%), moderate (50% to 75%), or severe (>75%); and by RA as <75% or > or =75% stenosis. RESULTS:The LR was 0.13 (95% CI = 0.09 to 0.19) for mild stenosis, 0.11 (95% CI = 0.08 to 0.15) for moderate stenosis, and 2.2 (95% CI = 1.9 to 3.1) for severe stenosis by MRA. CONCLUSIONS:Nonsevere stenosis can be sufficiently diagnosed by MRA and may not warrant RA. However, it may be insufficiently precise to establish severe RAS based on LR results. Therefore, for severe RAS by MRA, the decision to obtain RA can be made with the help of post-test probability, which is determined using pretest probability and LR.
journal_name
Am J Hypertensjournal_title
American journal of hypertensionauthors
Attallah N,Yee J,Gutierrez A,Musial J,Parasuraman Rdoi
10.1016/j.amjhyper.2003.07.016subject
Has Abstractpub_date
2003-12-01 00:00:00pages
987-92issue
12eissn
0895-7061issn
1941-7225pii
S0895706103010781journal_volume
16pub_type
杂志文章abstract::The results of ambulatory blood pressure monitoring (ABPM) in children after kidney transplant were analyzed to ascertain any alteration in circadian BP profile, degree of hypertension, and efficacy of therapy. The data were also compared with casual BP data and left ventricular mass index (LVMI). We have examined 30 ...
journal_title:American journal of hypertension
pub_type: 杂志文章
doi:10.1016/s0895-7061(97)00484-6
更新日期:1998-04-01 00:00:00
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abstract:BACKGROUND:The association between hypertension (HTN) and inflammatory biomarkers (interleukin-6 [IL-6] and high-sensitivity C-reactive protein [hsCRP]) in HIV-positive persons with CD4+ count >500 cells/mm3 is unknown. METHODS:We studied HTN in participants of the Strategic Timing of AntiRetroviral Treatment (START) ...
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Structural and functional changes involved in cardiac injury induced by diabetes mellitus, pressure-overload, or both conditions were evaluated. METHODS:Pressure-overload was established by suprarenal aortic banding in rats. Six weeks later, diabetes was induced by streptozotocin (STZ, 65 mg/kg, intraperito...
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更新日期:2009-11-01 00:00:00
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journal_title:American journal of hypertension
pub_type: 杂志文章
doi:10.1016/j.amjhyper.2005.09.005
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journal_title:American journal of hypertension
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journal_title:American journal of hypertension
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journal_title:American journal of hypertension
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journal_title:American journal of hypertension
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journal_title:American journal of hypertension
pub_type: 杂志文章,评审
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pub_type: 杂志文章,meta分析
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journal_title:American journal of hypertension
pub_type: 杂志文章
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journal_title:American journal of hypertension
pub_type: 杂志文章
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更新日期:1993-02-01 00:00:00
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更新日期:2016-06-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:American journal of hypertension
pub_type: 杂志文章
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journal_title:American journal of hypertension
pub_type: 杂志文章
doi:10.1038/ajh.2009.101
更新日期:2009-09-01 00:00:00
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journal_title:American journal of hypertension
pub_type: 杂志文章,评审
doi:10.1038/ajh.2007.62
更新日期:2008-03-01 00:00:00
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journal_title:American journal of hypertension
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1995-06-01 00:00:00
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journal_title:American journal of hypertension
pub_type: 杂志文章
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更新日期:1995-09-01 00:00:00
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pub_type: 杂志文章,评审
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