Circadian blood pressure overswinging in a physically fit, normotensive African American woman.

Abstract:

:Ambulatory blood pressure (BP) and heart rate (HR) were measured in a physically fit, normotensive postmenopausal African American woman, before and after 15 weeks of aerobic training. Mean BP, HR, and HR variability were normal at the outset and were further improved by training. Training had no effect on circadian BP variation, which exceeded gender- and age-specified limits, indicative of circadian hyperamplitude tension (CHAT). A 12-week treatment with the beta1-adrenoceptor blocker atenolol, 14 months post-training, normalized CHAT and HR variability and further reduced BP and HR. These results suggest beta1-adrenergic mediation of CHAT and its refractoriness to exercise training.

journal_name

Am J Hypertens

authors

Borer KT,Cornelissen G,Halberg F,Brook R,Rajagopalan S,Fay W

doi

10.1016/s0895-7061(02)02973-4

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

827-30

issue

9

eissn

0895-7061

issn

1941-7225

journal_volume

15

pub_type

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