Linkage of left ventricular early diastolic peak filling velocity to chromosome 5 in hypertensive African Americans: the HyperGEN echocardiography study.

abstract：:In a randomized double-blind, placebo-controlled, crossover study of isradipine (5 mg twice daily), effects on peripheral hemodynamic reflex responses were studied in nine patients (mean age 48 years) at baseline and after six weeks of active treatment. Assessments included vital signs, resting blood flow in the calf ...

journal_title：American journal of hypertension

authors： Duprez D,De Backer T,De Pue N,Hermans L,De Buyzere M,Clement DL

更新日期：1991-02-01 00:00:00

abstract：:Arterial stiffness has been known as a sign of cardiovascular risk since the 19th century. Despite this, accurate measurement and clinical utility have only emerged in recent times. Arterial stiffness and its hemodynamic consequences are now established as predictors of adverse cardiovascular outcome. They are easily ...

journal_title：American journal of hypertension

authors： Adji A,O'Rourke MF,Namasivayam M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Left atrial (LA) dilatation is associated with unfavorable outcome in hypertension. However, there are few data on clinical, demographic, and echocardiographic findings correlated with LA dilatation development. METHODS:From the Campania-Salute Network registry, we identified 5,375 hypertensive patients (52...

journal_title：American journal of hypertension

authors： Losi MA,Izzo R,Canciello G,Giamundo A,Manzi MV,Strisciuglio T,Stabile E,De Luca N,de Simone G,Trimarco B

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The elevation of left ventricular filling pressure (LVFP) could be an important prognostic factor in patients with hypertension. We hypothesized that noninvasive brachial-ankle pulse wave velocity (baPWV) is associated with increased LVFP in hypertensive patients with LV hypertrophy (LVH). METHODS:We enroll...

journal_title：American journal of hypertension

authors： Park KH,Park WJ,Kim MK,Jung JH,Choi S,Cho JR,Kim HS,Lee N,Cho GY

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Subjects with resistant hypertension present high prevalence of a nondipper blood pressure (BP) pattern, associated with increased risk of cardiovascular events. Nondipping is partly related to the absence of 24-h therapeutic coverage in hypertensives treated with single morning doses. METHODS:We studied th...

journal_title：American journal of hypertension

authors： Hermida RC,Ayala DE,Mojón A,Fernández JR

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Little is known about the influence of blood pressure (BP) on cardiovascular disease (CVD) outcomes among Asian populations. METHODS:We examined population attributable fractions (PAFs) and hazard ratios (HRs) associated with BP in relation to stroke and coronary heart disease (CHD) incident and mortality w...

journal_title：American journal of hypertension

authors： Ikeda A,Iso H,Yamagishi K,Inoue M,Tsugane S

更新日期：2009-03-01 00:00:00

abstract：:After nephrectomy, the level of arterial pressure is determined by the permitted degree of fluid volume expansion. With kidneys present, the fundamental requirement for fluid volume homeostasis is met by maintaining the balance between sodium and water intake and output. When one-kidney, one-clip (1-K,1-C) hypertensio...

journal_title：American journal of hypertension

authors： Ledingham JM

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:High salt diet causes cardiac hypertrophy and fibrosis and increases cardiac aldosterone, while decreasing plasma aldosterone. The present study assessed, in Wistar rats, the effect of high salt diet on left and right ventricle (LV and RV, respectively) weight and fibrosis both with and without the aldostero...

journal_title：American journal of hypertension

authors： Lal A,Veinot JP,Leenen FH

更新日期：2003-04-01 00:00:00

abstract：:Pneumonia is a major direct cause of death in the elderly. Although aspiration based on a reduced cough reflex is one of the causes of pneumonia in the elderly, there are few studies of angiotensin-I converting enzyme inhibitors (ACE inhibitors), which are antihypertensive drugs that induce cough, as a factor influenc...

journal_title：American journal of hypertension

authors： Okaishi K,Morimoto S,Fukuo K,Niinobu T,Hata S,Onishi T,Ogihara T

更新日期：1999-08-01 00:00:00

abstract：:The present study was designed to investigate the role of the autonomic nervous system in experimental hypertension induced by chronic administration of N-nitro-L-arginine methyl ester (L-NAME) in the drinking water (1 mg/mL) over 6 days. L-NAME ingestion caused a large rise in resting mean arterial pressure (MAP) (17...

journal_title：American journal of hypertension

authors： Cunha RS,Cabral AM,Vasquez EC

更新日期：1993-09-01 00:00:00

abstract：:Atherosclerosis is increasingly recognized as an inflammatory vascular disease, and high blood pressure (BP) has been suggested to exert a proinflammatory action. Whether plasma viscosity (PV), a major determinant of blood flow in microcirculation and a marker of systemic inflammation and cardiovascular risk, is incre...

journal_title：American journal of hypertension

authors： Ciuffetti G,Schillaci G,Lombardini R,Pirro M,Vaudo G,Mannarino E

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Left ventricular (LV) hypertrophy and impaired diastolic function may occur early in systemic hypertension, but longitudinal studies are missing. METHODS:We performed an echocardiographic follow-up study in young initially normotensive male offspring of hypertensive (OHyp) (n = 25) and normotensive (ONorm) ...

journal_title：American journal of hypertension

authors： Aeschbacher BC,Hutter D,Fuhrer J,Weidmann P,Delacrétaz E,Allemann Y

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:As hypertension, obesity, and leanness are reported to be associated with poor cognitive function, it is possible that obesity or leanness in hypertensive patients may also be associated strongly with poor cognitive function. METHODS:We recruited 184 elderly hypertensive patients comprising 93 very elderly ...

journal_title：American journal of hypertension

authors： Sakakura K,Hoshide S,Ishikawa J,Momomura S,Kawakami M,Shimada K,Kario K

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Increased sodium intake has been positively associated with high blood pressure (BP) and hypertensive target organ damage, but associations with cardiac structure in nonhypertensive individuals have yielded inconsistent results. We tested the hypothesis that sodium intake is associated with left ventricular ...

journal_title：American journal of hypertension

authors： Dhingra R,Pencina MJ,Benjamin EJ,Levy D,Larson MG,Meigs JB,Rifai N,D'Agostino RB Sr,Vasan RS

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:The effect of age on the augmentation index (AI) differs between young adults and the elderly, and the AI reaches a plateau after the age of 60 years. We examined whether the effects of age and an elevation in blood pressure on the AI differ between young adults and the elderly, between subjects with and wit...

journal_title：American journal of hypertension

authors： Tomiyama H,Odaira M,Kimura K,Matsumoto C,Shiina K,Eguchi K,Miyashita H,Shimada K,Yamashina A

更新日期：2014-12-01 00:00:00

abstract：:Previous studies showed that alpha 2-adrenergic receptors and imidazoline-guanidinium receptive sites (IGRS) are colocalized in rabbit and human renal proximal tubule. In the present study we investigated the localization of these two binding sites in the renal medulla from human kidney. Binding studies performed with...

journal_title：American journal of hypertension

authors： Lachaud V,Limon I,Tesson F,Coupry I,Parini A

更新日期：1992-04-01 00:00:00

abstract：:Arterial hypertension is the most common chronic medical condition requiring office visits to physicians and is a major contributing factor to the development of myocardial infarction and stroke. Its importance as a cardiovascular risk factor is at least as significant in women as in men; however, the ever-growing lit...

journal_title：American journal of hypertension

authors： Ruilope LM,Suarez C

更新日期：1997-10-01 00:00:00

abstract：:We investigated whether the slow pressor action of small doses of angiotensin II (ANG II) administered to rats was accompanied by the development of structural vascular changes. Male Sprague-Dawley rats (350 to 400 g) were given ANG II intraperitoneally, 200 ng/kg/min, for 7 to 10 days or 6 weeks, or 100 ng/kg/min for...

journal_title：American journal of hypertension

authors： Simon G,Cserep G,Limas C

更新日期：1995-01-01 00:00:00

abstract：:The effect of fish oil on potassium efflux and basal tension in aortas from stroke prone spontaneously hypertensive rats (SHRSP) was evaluated. Four-week-old male Wistar-Kyoto rats (WKY) and SHRSP were divided into two groups: one received a 5% corn oil diet; the other a 5% menhaden oil diet. After 15 weeks, mean syst...

journal_title：American journal of hypertension

authors： Smith JM,Paulson DJ,Labak S

更新日期：1992-07-01 00:00:00

abstract：:We have previously reported that young, primigravid, African-American women who developed preeclampsia exhibited insulin resistance (elevated fasting insulin:glucose ratios) and abnormal intracellular free calcium ([Ca2+]i) metabolism as early as the second trimester of pregnancy. To determine if these abnormalities p...

journal_title：American journal of hypertension

authors： Sowers JR,Standley PR,Jacober S,Niyogi T,Simpson L

更新日期：1993-04-01 00:00:00

abstract：:In many reports, the prevalence of target organ damage in renovascular hypertension (RVH) appears to be higher than in essential hypertension (EH). Since in most studies the renal artery stenosis is part of a diffuse atherosclerotic disease, it is not known whether these complications are due to RVH itself or to the v...

journal_title：American journal of hypertension

authors： Losito A,Fagugli RM,Zampi I,Parente B,de Rango P,Giordano G,Cao P

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Remnant-like lipoprotein particle cholesterol (RLP-C) is a highly atherogenic factor. RLP-C induces endothelial dysfunction and is associated with hyperinsulinemia. This study was designed to determine whether high plasma RLP-C levels predispose to the development of hypertension in subjects with normal bloo...

journal_title：American journal of hypertension

authors： Kasahara A,Adachi H,Hirai Y,Enomoto M,Fukami A,Yoshikawa K,Esaki E,Yokoi K,Ogata K,Tsukagawa E,Obuchi A,Yoshimura A,Nakamura S,Imaizumi T

更新日期：2013-06-01 00:00:00

abstract：:This article examines the results of the Joint National Committee's Fifth Report on the treatment of hypertension (JNC-V), especially regarding the economic arguments put forth therein. Economics are a poor basis for treatment decisions, as the cheapest therapies may not be the best for any given patient. Broad treatm...

journal_title：American journal of hypertension

authors： Ménard J

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Family history of hypertension is a primary predictor of high blood pressure (BP). This study attempted to determine whether there is a gradual increase in BP between individuals with two hypertensive parents, one hypertensive parent, and normotensive parents and whether this increase is apparent with both a...

journal_title：American journal of hypertension

authors： Goldstein IB,Shapiro D,Guthrie D

更新日期：2006-05-01 00:00:00

abstract：:The hypotensive effect of isradipine was assessed in 26 male patients, aged 40 to 64 years, with hypertension. After withdrawal of previous antihypertensive treatment and a four-week placebo period, patients were randomized into a double-blind active-treatment period of eight weeks to receive either placebo or 1.25 to...

journal_title：American journal of hypertension

authors： Viskoper JR,Laszt A,Faraggi D

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:The efficacy and safety of angiotensin receptor blockers (ARBs) in the older population is unclear. OBJECTIVES:To determine the efficacy and safety of ARBs in older patients. METHODS:Randomized trials that compared ARBs to control and reported clinical outcomes in patients with a mean age of 65 years or ol...

journal_title：American journal of hypertension

authors： Elgendy IY,Huo T,Chik V,Pepine CJ,Bavry AA

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:There is evidence that diuretics and beta blockers impair glucose tolerance, whereas calcium channel blockers and angiotensin converting enzyme blockers lack this metabolic effect. We compared the effect of a combination therapy with a nondihydropyridine calcium channel blocker plus an angiotensin converting...

journal_title：American journal of hypertension

authors： Holzgreve H,Nakov R,Beck K,Janka HU

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:The mechanisms by which heme oxygenase (HO) improves glucose metabolism in essential hypertension are not completely understood. Because dysfunctional insulin signaling is associated with elevated inflammation and high cholesterol and triglycerides, we investigated the effects of HO on the proinflammatory ma...

journal_title：American journal of hypertension

authors： Ndisang JF,Mishra M

更新日期：2013-09-01 00:00:00

abstract：:Increased dietary sodium intake has been associated with an increase in blood pressure as well as a decrease in insulin-mediated glucose disposal in young healthy adults. The purpose of this study was to determine whether dietary sodium intake is associated with changes in oral glucose tolerance, insulin sensitivity, ...

journal_title：American journal of hypertension

authors： Dengel DR,Mayuga RS,Kairis GM,Goldberg AP,Weir MR

更新日期：1997-09-01 00:00:00

abstract：:Cardiovascular morbid events occur as a consequence of vascular and cardiac disease, which can be identified long before symptoms of organ involvement become apparent. Early detection of abnormalities in the small arteries, especially deficiency of endothelial nitric oxide bioactivity, and of structural changes of rem...

journal_title：American journal of hypertension

authors： Cohn JN

更新日期：2001-06-01 00:00:00