Effect of surgical treatment on hypertension in Cushing's syndrome.

Abstract:

:The effect of a surgical cure of hypercortisolism on hypertension in 54 patients with Cushing's syndrome was assessed. The correlation between preoperative duration of hypertension and posttreatment blood pressure was significant (P < .01). Restoration of normal cortisol was associated with blood pressure normalization in 39 out of 54 cases. Duration of hypertension of patients with normalized blood pressure was significantly shorter than that of patients with persistent hypertension postoperatively (P < .0001). Duration of hypertension, ie, long-lasting exposure to increased cortisol, appears to be the determinant of persistent hypertension following successful surgery in Cushing's syndrome.

journal_name

Am J Hypertens

authors

Fallo F,Sonino N,Barzon L,Pistorello M,Pagotto U,Paoletta A,Boscaro M

doi

10.1016/0895-7061(95)00299-5

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

77-80

issue

1

eissn

0895-7061

issn

1941-7225

pii

0895706195002995

journal_volume

9

pub_type

临床试验,杂志文章
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    doi:

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