Obesity hypertension.

abstract：:There is evidence that hyperinsulinemia and insulin resistance play a role in the development of hypertension. Accordingly, in our ongoing longitudinal study of pregnancy-induced hypertension, we have measured fasting levels of insulin and glucose at 18 to 25 weeks gestation in 140 nulliparous African-American women f...

journal_title：American journal of hypertension

authors： Sowers JR,Saleh AA,Sokol RJ

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Obesity has been described as a predictor of cardiovascular mortality, and some studies have reported an association with obesity and increased aortic stiffness. Other studies have not identified obesity to be an independent risk factor. Therefore, the purpose of our study was to determine the association be...

journal_title：American journal of hypertension

authors： Rodrigues SL,Baldo MP,Lani L,Nogueira L,Mill JG,Sa Cunha Rd

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:In patients free from overt cardiac disease, R wave in aVL lead (RaVL) is strongly correlated with left ventricular mass index (LVMI) assessed by transthoracic echocardiography. The aim of the present study was to extend this finding to other settings (cardiomyopathy or conduction disorders), by comparing EC...

journal_title：American journal of hypertension

authors： Courand PY,Grandjean A,Charles P,Paget V,Khettab F,Bricca G,Boussel L,Lantelme P,Harbaoui B

更新日期：2015-08-01 00:00:00

abstract：:Fenoldopam (Corlopam), a new dopaminergic agent in clinical development by SmithKline Beecham Pharmaceuticals, is a dopamine-1 (DA1) agonist at post-synaptic dopamine receptors. Preclinical and clinical studies have demonstrated that it is a potent renal vasodilator as well as a peripheral vasodilator. In both normal ...

journal_title：American journal of hypertension

authors： Holcslaw TL,Beck TR

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Circulating blood levels of human urotensin II (U-II), the most potent vasoconstrictor peptide identified to date, are increased in patients with essential hypertension. Our previous studies showed that U-II accelerates human macrophage foam cell formation and vascular smooth muscle cell proliferation, sugge...

journal_title：American journal of hypertension

authors： Suguro T,Watanabe T,Ban Y,Kodate S,Misaki A,Hirano T,Miyazaki A,Adachi M

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The aims of this study were to document the presence of phospholipase C (PLC) isozymes beta(1), gamma(1), and delta(1) in freshly isolated renal glomeruli and resistance vessels, to compare their expression and activity to that in aorta, and to contrast values between 6-week-old Wistar-Kyoto (WKY) controls a...

journal_title：American journal of hypertension

authors： Peng Z,Dang A,Arendshorst WJ

更新日期：2007-01-01 00:00:00

abstract：:To determine whether the benefits of antihypertensive treatment vary according to dipper status, 811 asymptomatic elderly Japanese hypertensives underwent 24-h ambulatory blood pressure monitoring. During a mean follow-up period of 41 months, 32 stroke events were observed in patients who remained nonmedicated (n = 38...

journal_title：American journal of hypertension

authors： Hoshide Y,Kario K,Schwartz JE,Hoshide S,Pickering TG,Shimada K

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Substantial epidemiological evidence documents diverse health benefits, including reduced risks of hypertension, associated with diets high in fiber. Few studies, however, have investigated the extent to which dietary fiber intake in early pregnancy is associated with reductions in preeclampsia risk. We asse...

journal_title：American journal of hypertension

authors： Qiu C,Coughlin KB,Frederick IO,Sorensen TK,Williams MA

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Hypertension is a risk factor for coronary heart disease (CHD), but the causes of hypertension remain largely unknown. Genetic variation is thought to contribute to the etiology of hypertension. We tested a single-nucleotide polymorphism (SNP) (Lys67Arg, rs197922) in the Golgi SNAP Receptor Complex Member 2 ...

journal_title：American journal of hypertension

authors： Meyer TE,Shiffman D,Morrison AC,Rowland CM,Louie JZ,Bare LA,Ross DA,Arellano AR,Chasman DI,Ridker PM,Pankow JS,Coresh J,Malloy MJ,Kane JP,Ellis SG,Devlin JJ,Boerwinkle E

更新日期：2009-02-01 00:00:00

abstract：:Thromboembolic complications such as ischemic stroke and myocardial infarction are significantly more frequent in patients with arterial hypertension. From the available intervention studies, it appears that pharmacologic treatment of hypertension-at least with diuretics and beta-blockers-may more effectively protect ...

journal_title：American journal of hypertension

authors： Lottermoser K,Weisser B,Hertfelder HJ,Wöstmann B,Vetter H,Düsing R

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Exaggerated sympathetic cardiovascular (CV) reactivity to stress associates with elevated risk for clinical and preclinical end points of CV disease. It would be useful to identify these individuals, preferably from feasible measurements commonly used in health care. Our study examined the association betwee...

journal_title：American journal of hypertension

authors： Hintsala HE,Kiviniemi AM,Antikainen R,Mäntysaari M,Jokelainen J,Hassi J,Tulppo MP,Herzig KH,Keinänen-Kiukaanniemi S,Rintamäki H,Jaakkola JJK,Ikäheimo TM

更新日期：2019-05-09 00:00:00

abstract：:We assessed the efficacy of monotherapy with trandolapril, an angiotensin converting enzyme (ACE) inhibitor, and of verapamil slow-release (SR), a calcium antagonist, each in a range of three doses as monotherapy, and in the nine possible combinations of therapy in patients with stage I to III diastolic hypertension. ...

journal_title：American journal of hypertension

authors： DeQuattro V,Lee D

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Inflammation is an independent risk factor for high blood pressure, and as a consequence inflammatory cytokines could be related with left ventricular hypertrophy (LVH). We sought to assess the association and predictive role of different cytokine levels with LVH in a group of patients with essential hyperte...

journal_title：American journal of hypertension

authors： Roselló-Lletí E,Rivera M,Martínez-Dolz L,González Juanatey JR,Cortés R,Jordán A,Morillas P,Lauwers C,Calabuig JR,Antorrena I,de Rivas B,Portolés M,Bertomeu V

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Blood pressure (BP) response to the cold pressor test (CPT) has been associated with increased risk of cardiovascular disease. We studied risk factors associated with BP response to CPT. METHODS:We conducted the CPT among 2,682 individuals in rural north China. BP was measured using a standard mercury sphyg...

journal_title：American journal of hypertension

authors： Zhang M,Zhao Q,Mills KT,Chen J,Li J,Cao J,Gu D,He J

更新日期：2013-09-01 00:00:00

abstract：:Neutral metalloendopeptidase (NEP) inhibitors delay atrial natriuretic factor (ANF) catabolism and potentiate biological responses to ANF. We describe biochemical and pharmacological profiles of a novel NEP inhibitor, SCH 42354 (N-[2(S)-(mercaptomethyl)-3-(2-methylphenyl)-4-oxopropyl]-L-methionine and its orally activ...

journal_title：American journal of hypertension

authors： Watkins RW,Vemulapalli S,Chiu PJ,Foster C,Smith EM,Neustadt B,Haslanger M,Sybertz EJ

更新日期：1993-05-01 00:00:00

abstract：:Ambulatory blood pressure (BP) and heart rate (HR) were measured in a physically fit, normotensive postmenopausal African American woman, before and after 15 weeks of aerobic training. Mean BP, HR, and HR variability were normal at the outset and were further improved by training. Training had no effect on circadian B...

journal_title：American journal of hypertension

authors： Borer KT,Cornelissen G,Halberg F,Brook R,Rajagopalan S,Fay W

更新日期：2002-09-01 00:00:00

abstract：:The levels and molecular form of atrial natriuretic peptide-like immunoreactivity (ANP-LI) in human atrial tissue were investigated. The levels of right atrial ANP-LI were significantly higher in mitral disease than in other cardiac or noncardiac diseases. The increased ANP-LI was mainly accounted for by an increase i...

journal_title：American journal of hypertension

authors： Naruse M,Hiroe M,Naruse K,Nagata M,Ohno H,Hashimoto A,Koyanagi H,Sekiguchi M,Demura H,Hirosawa K

更新日期：1990-02-01 00:00:00

abstract：:The principal aim of the present study was to determine the relationship of ambulatory blood pressure (BP) to urinary electrolyte excretion in normotensives. Twenty-five young adults underwent ambulatory BP and heart rate monitoring while collecting urine over 24 h. The correlations of 24 h urine sodium excretion and ...

journal_title：American journal of hypertension

authors： Ruddy MC,Arora A,Malka ES,Bialy GB

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Low birth weight has been associated with increased risk of hypertension later in life. The aim of this study was to evaluate the association between birth weight and blood pressure (BP) in healthy 9- to 10-year-old Icelandic children. METHODS:Each child underwent 4 seated BP measurements, and the BP percen...

journal_title：American journal of hypertension

authors： Steinthorsdottir SD,Eliasdottir SB,Indridason OS,Palsson R,Edvardsson VO

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Calcium channel blockers such as amlodipine are effective antihypertensive agents. In this study we investigated the effects of amlodipine on vascular oxidative stress, expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1), and endothelial function in angiotensin (Ang) II-infused ra...

journal_title：American journal of hypertension

authors： Zhou MS,Jaimes EA,Raij L

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:In experimental renovascular hypertension, aldosterone has been implicated in myocardial remodeling and fibrosis, but it is uncertain whether excess aldosterone effects left ventricular structure and function in hypertensive patients. METHODS:Hypertensive patients from the Cardiovascular Center of the New Y...

journal_title：American journal of hypertension

authors： Goldkorn R,Yurenev A,Blumenfeld J,Fishman D,Devereux RB

更新日期：2002-04-01 00:00:00

abstract：:We sought to determine whether reductions in blood pressure in hypertensives after acute exercise persist for more than the 2 to 3 h found in controlled laboratory settings. Subjects (n = 11) were obese (32 +/- 4% body fat), sedentary (VO2max 27 +/- 4 mL/kg/min) 60 +/- 6-year-old men with stage 1 or 2 essential hypert...

journal_title：American journal of hypertension

authors： Taylor-Tolbert NS,Dengel DR,Brown MD,McCole SD,Pratley RE,Ferrell RE,Hagberg JM

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Dyslipidemia in hypertensive sibships may be characterized by atherogenic small low-density lipoprotein (LDL) particles. Whether LDL particle size is associated with the extent of coronary atherosclerosis in hypertensive sibships is unknown. METHODS:Subjects (n = 792, mean age 62 years, 60% women) were asce...

journal_title：American journal of hypertension

authors： Kullo IJ,Bailey KR,McConnell JP,Peyser PA,Bielak LF,Kardia SL,Sheedy PF 2nd,Boerwinkle E,Turner ST

更新日期：2004-09-01 00:00:00

abstract：:Cold- and insulin-mediated release of angiotensin II (AII) and endothelin-1 (ET-1), as well as vascular reactivity to exogenous ET-1 and to insulin, were compared in hypertensive and normotensive subjects. Peripheral vascular release of AII and of ET-1 was investigated in 10 hypertensive (H; 29.2+/-5.8 years) and 12 n...

journal_title：American journal of hypertension

authors： Gasic S,Ratheiser K,Wagner O,Nowotny P,Vierhapper H,Waldhäusl W

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Central aortic blood pressure (CBP) and CBP-derived parameters are independent predictors of cardiovascular risk. Angiotensin II receptor blockers (ARBs) or angiotensin-converting enzyme inhibitors plus calcium channel blockers are the recommended first-line treatments in hypertensive diabetic patients; howe...

journal_title：American journal of hypertension

authors： Redon J,Pichler G,Missed Dose Study Group.

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Both increased night blood pressure (BP) and nondipping are associated with worse cardiovascular risk and prognosis. However, as they are often related features, their relative importance has been difficult to assess separately. In this study we address separate associations of nocturnal hypertension and non...

journal_title：American journal of hypertension

authors： de la Sierra A,Gorostidi M,Banegas JR,Segura J,de la Cruz JJ,Ruilope LM

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Isolated systolic hypertension (ISH), more so than any other hypertension subtype, increases the risk for stroke and coronary heart disease. The prevalence of ISH versus other hypertension subtypes in the general Chinese adult population is not known. METHODS:The prevalence of isolated systolic and isolated...

journal_title：American journal of hypertension

authors： Huang J,Wildman RP,Gu D,Muntner P,Su S,He J

更新日期：2004-10-01 00:00:00

abstract：:The influence of increased lability of blood pressure on the development of aortic atherosclerosis was examined. Because sinoaortic denervation (SAD) produced increased lability of blood pressure without blood pressure elevation, the development of atheromatous plaque was examined in SAD rats. These rats were fed a hi...

journal_title：American journal of hypertension

authors： Sasaki S,Yoneda Y,Fujita H,Uchida A,Takenaka K,Takesako T,Itoh H,Nakata T,Takeda K,Nakagawa M

更新日期：1994-05-01 00:00:00

abstract：:Although left ventricular hypertrophy (LVH) is an adaptive response to the increased load imposed on the heart in patients with hypertension, it ultimately is itself a major risk factor for cardiovascular disease. The influence of LVH on left ventricular function and on the coronary circulation, and the occurrence of ...

journal_title：American journal of hypertension

authors： Clement DL,De Buyzere M,Duprez D

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Preeclampsia is a human pregnancy-associated syndrome associated with hypertension, proteinuria, and endothelial dysfunction. We tested whether increased reactive oxygen species (superoxide and peroxynitrite) production and decreased bioavailability of the endothelial nitric oxide (NO) synthase (eNOS) cofact...

journal_title：American journal of hypertension

authors： Mitchell BM,Cook LG,Danchuk S,Puschett JB

更新日期：2007-12-01 00:00:00