Blood pressure variability and urinary electrolyte excretion in normotensive adults.


:The principal aim of the present study was to determine the relationship of ambulatory blood pressure (BP) to urinary electrolyte excretion in normotensives. Twenty-five young adults underwent ambulatory BP and heart rate monitoring while collecting urine over 24 h. The correlations of 24 h urine sodium excretion and the ratio of sodium/potassium excretion with systolic BP in the laboratory (r = 0.12 and 0.24), ambulatory awake (r = 0.11 and 0.24), and ambulatory asleep (r = 0.24 and 0.31) settings were all in the positive direction but not significant. However, 24 h sodium excretion did correlate significantly and positively with awake and asleep ambulatory systolic (r = 0.45 and 0.41, P < .05) and diastolic (r = 0.42 and 0.43, P < .05) coefficients of variability. Thus, in normotensives on an unlimited diet, 24 h urinary sodium was more closely related to ambulatory BP variability than to BP level.


Am J Hypertens


Ruddy MC,Arora A,Malka ES,Bialy GB




Has Abstract


1993-06-01 00:00:00




6 Pt 1










  • Rationale and design of the genotype-blinded trial of torasemide for the treatment of hypertension (BHF UMOD).

    abstract:BACKGROUND:There is evidence from genome wide association study that single-nucleotide polymorphisms (SNPs) in the 5' end of the uromodulin gene (UMOD) affect uromodulin excretion and blood pressure (BP). Uromodulin is almost exclusively expressed in the thick ascending limb of the loop of Henle (TAL) and its effect on...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: McCallum L,Brooksbank K,McConnachie A,Aman A,Lip S,Dawson J,MacIntyre IM,MacDonald TM,Webb DJ,Padmanabhan S

    更新日期:2020-10-21 00:00:00

  • Short-term antihypertensive medication does not exacerbate sleep-disordered breathing in newly diagnosed hypertensive patients.

    abstract::It has been speculated for some time that various antihypertensive medications may have a deleterious effect on respiration during sleep and thereby enhance the apparent association between hypertension and sleep apnea/hypopnea (SAH). However, there are few data to support this contention. The present study used a dou...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Bartel PR,Loock M,Becker P,Robinson E,van der Meyden C,Rossouw S

    更新日期:1997-06-01 00:00:00

  • Polymorphisms of Leptin (G2548A) and Leptin Receptor (Q223R and K109R) Genes and Blood Pressure During Pregnancy and the Postpartum Period: A Cohort.

    abstract:BACKGROUND:The genetic component related to blood pressure (BP) changes during pregnancy is still not elucidated. Thus, the aim of the study was to evaluate the association between leptin and leptin receptor polymorphisms and systolic (SBP) and diastolic BP (DBP) variation during pregnancy and the postpartum period. M...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Farias DR,Franco-Sena AB,Rebelo F,Salles GF,Struchiner CJ,Martins MC,Kac G

    更新日期:2017-02-01 00:00:00

  • Factors associated with blood pressure response to the cold pressor test: the GenSalt Study.

    abstract:BACKGROUND:Blood pressure (BP) response to the cold pressor test (CPT) has been associated with increased risk of cardiovascular disease. We studied risk factors associated with BP response to CPT. METHODS:We conducted the CPT among 2,682 individuals in rural north China. BP was measured using a standard mercury sphyg...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Zhang M,Zhao Q,Mills KT,Chen J,Li J,Cao J,Gu D,He J

    更新日期:2013-09-01 00:00:00

  • Circadian blood pressure overswinging in a physically fit, normotensive African American woman.

    abstract::Ambulatory blood pressure (BP) and heart rate (HR) were measured in a physically fit, normotensive postmenopausal African American woman, before and after 15 weeks of aerobic training. Mean BP, HR, and HR variability were normal at the outset and were further improved by training. Training had no effect on circadian B...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Borer KT,Cornelissen G,Halberg F,Brook R,Rajagopalan S,Fay W

    更新日期:2002-09-01 00:00:00

  • Gender-specific correlates of leptin with hypertension-related phenotypes in African Americans.

    abstract::Leptin may be a link in the relationship of obesity with hypertension. We evaluated associations of leptin with blood pressure (BP) in 54 normotensive and 114 hypertensive African American individuals. Plasma leptin was higher (P <.03) in hypertensive women than in normotensive women, although body mass index did not ...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: El-Gharbawy AH,Kotchen JM,Grim CE,Kaldunski M,Hoffmann RG,Pausova Z,Hamet P,Kotchen TA

    更新日期:2002-11-01 00:00:00

  • Social and economic factors as obstacles to blood pressure control.

    abstract::Further improvement in blood pressure control at the population level will result from dealing with hard-to-solve problems, such as access to care, long-term management of a chronic disease, and societal influences on lifestyle. Additional knowledge and experimental data are needed, reinforced by clear public health c...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Lang T

    更新日期:1998-07-01 00:00:00

  • Developmental studies demonstrate age-dependent elevation of renin activity in TGR(mRen2)27 rats.

    abstract::The objective of the present study was to determine the relationship between plasma renin levels, and the development of hypertension and cardiac hypertrophy in TGR (mREN2)27 hypertensive rats. Systolic blood pressure and left ventricular mass index (LVMI) were measured in transgenic heterozygote and normotensive Spra...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Véniant M,Whitworth CE,Ménard J,Sharp MG,Gonzales MF,Bruneval P,Mullins JJ

    更新日期:1995-12-01 00:00:00

  • Left ventricular mass is better correlated with arising blood pressure than with office or occasional blood pressure.

    abstract::The peak incidence of cardiovascular complications in the morning points to a possible role of the abrupt increase in blood pressure on arising. However, there is as yet no firm evidence linking the extent of the elevation in blood pressure on arising and the risk of cardiovascular complications. We sought a correlati...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Gosse P,Ansoborlo P,Lemetayer P,Clementy J

    更新日期:1997-05-01 00:00:00

  • Differentiation and growth of vascular smooth muscle cells in experimental hypertension.

    abstract::In this review we have analyzed the present knowledge about the differentiation and growth processes in vascular smooth muscle cells (SMC) in hypertension. The study of smooth muscle (SM) and nonmuscle (NM) myosin isoform expression has permitted us to identify a three-stage specific maturational pathway, namely, feta...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,评审


    authors: Pauletto P,Sarzani R,Rappelli A,Chiavegato A,Pessina AC,Sartore S

    更新日期:1994-07-01 00:00:00

  • The relationship between birth weight and blood pressure in childhood: a population-based study.

    abstract:BACKGROUND:Low birth weight has been associated with increased risk of hypertension later in life. The aim of this study was to evaluate the association between birth weight and blood pressure (BP) in healthy 9- to 10-year-old Icelandic children. METHODS:Each child underwent 4 seated BP measurements, and the BP percen...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Steinthorsdottir SD,Eliasdottir SB,Indridason OS,Palsson R,Edvardsson VO

    更新日期:2013-01-01 00:00:00

  • Magnetic resonance imaging compared to echocardiography to assess left ventricular mass in the hypertensive patient.

    abstract::Echocardiography (ECHO) is useful to document changes in left ventricular mass (LVM) in groups of patients, but may be too variable for use in the individual patient. Magnetic resonance imaging (MRI) may be a more precise and reliable method to quantify the mass of the left ventricule. This study reports the accuracy,...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Bottini PB,Carr AA,Prisant LM,Flickinger FW,Allison JD,Gottdiener JS

    更新日期:1995-03-01 00:00:00

  • Short-term oral folic acid supplementation enhances endothelial function in patients with type 2 diabetes.

    abstract:BACKGROUND:Endothelial dysfunction and arterial stiffening are commonly observed in type 2 diabetes. These abnormalities might be secondary to increased plasma concentrations of homocysteine. We sought to determine whether oral folic acid supplementation, by lowering homocysteine levels, enhanced endothelial function a...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Mangoni AA,Sherwood RA,Asonganyi B,Swift CG,Thomas S,Jackson SH

    更新日期:2005-02-01 00:00:00

  • Carvedilol action is dependent on endogenous production of nitric oxide.

    abstract:BACKGROUND:Carvedilol is known to be an adrenoreceptor blocker and free radical scavenger, used in hypertension and cardiac failure. However, its therapeutic actions cannot be fully explained by these mechanisms. In these studies, we tested the hypothesis that carvedilol action is associated with the synthesis/release ...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Afonso RA,Patarrao RS,Macedo MP,Carmo MM

    更新日期:2006-04-01 00:00:00

  • Increase of calmodulin activator in hypertension. Modulation by dietary sodium and calcium.

    abstract::The aim of this study was to investigate the effects of dietary calcium and sodium on blood pressure (BP) in normotensive rats (Wistar, WKY), spontaneously hypertensive rats (SHR) and Dahl rats and on calmodulin (CaM) activator, a newly-discovered hydrophobic compound that increases CaM activity in SHR and spontaneous...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Chang E,Kunes J,Hamet P,Tremblay J

    更新日期:1990-08-01 00:00:00

  • Relationship Between Carotid Atherosclerosis and Pulse Pressure with Renal Hemodynamics in Hypertensive Patients.

    abstract:BACKGROUND:Structural atherosclerotic damage, arterial stiffness, pulse pressure (PP), and renal hemodynamics may interact and influence each other. Renal resistance index (RRI) appears as a good indicator of systemic vascular changes. The aim of our study was to assess the independent relationships of carotid intima-m...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Geraci G,Mulè G,Costanza G,Mogavero M,Geraci C,Cottone S

    更新日期:2016-04-01 00:00:00

  • Association of blood pressure and cardiovascular mortality in India: Mumbai cohort study.

    abstract:BACKGROUND:To determine all-cause and circulatory system (cardiovascular)-related mortality in subjects with different grades of hypertension, we performed a prospective study. METHODS:A total of 148,173 individuals aged > or =35 years were recruited in Mumbai, India in years 1991-1997. Clinical history and anthropome...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Pednekar MS,Gupta R,Gupta PC

    更新日期:2009-10-01 00:00:00

  • Role of neurohumoral systems for pressure induced left ventricular hypertrophy in experimental supravalvular aortic stenosis in rats.

    abstract::We studied the role of the sympathetic nervous system and the renin angiotensin system for pressure induced left ventricular hypertrophy (LVH) in 135 rats with experimental supravalvular aortic stenosis (AS). We induced this condition by a silver clip on the ascending aorta, when body weight (BW) was 90 to 100 g. Symp...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Kromer EP,Elsner D,Riegger GA

    更新日期:1991-06-01 00:00:00

  • Influences of different antihypertensive treatments on indices of systemic mineral metabolism.

    abstract::A negative calcium balance has previously been described in human hypertension with low levels of plasma ionized calcium (Ca2+) and an increased urinary excretion of calcium. The cause of this disturbance in mineral metabolism is not known, nor is it known if this derangement could be abolished if blood pressure is re...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Lind L,Hänni A,Hvarfner A,Pollare T,Ljunghall S,Lithell H

    更新日期:1994-04-01 00:00:00

  • Ambulatory blood pressure and family history of hypertension in healthy men and women.

    abstract:BACKGROUND:Family history of hypertension is a primary predictor of high blood pressure (BP). This study attempted to determine whether there is a gradual increase in BP between individuals with two hypertensive parents, one hypertensive parent, and normotensive parents and whether this increase is apparent with both a...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Goldstein IB,Shapiro D,Guthrie D

    更新日期:2006-05-01 00:00:00

  • Association of microalbuminuria with brachial-ankle pulse wave velocity: the Ohasama study.

    abstract:BACKGROUND:Microalbuminuria is recognized as a marker of generalized vascular dysfunction. However, the associations between microalbuminuria and pulse wave velocity (PWV), carotid intima-media thickness (IMT), and ambulatory blood pressure (ABP), respectively, have not been investigated. METHODS:Brachial-ankle PWV (b...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Ishikawa T,Hashimoto J,Morito RH,Hanazawa T,Aikawa T,Hara A,Shintani Y,Metoki H,Inoue R,Asayama K,Kikuya M,Ohkubo T,Totsune K,Hoshi H,Satoh H,Imai Y

    更新日期:2008-04-01 00:00:00

  • High Home Blood Pressure Variability Associates With Exaggerated Blood Pressure Response to Cold Stress.

    abstract:BACKGROUND:Exaggerated sympathetic cardiovascular (CV) reactivity to stress associates with elevated risk for clinical and preclinical end points of CV disease. It would be useful to identify these individuals, preferably from feasible measurements commonly used in health care. Our study examined the association betwee...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Hintsala HE,Kiviniemi AM,Antikainen R,Mäntysaari M,Jokelainen J,Hassi J,Tulppo MP,Herzig KH,Keinänen-Kiukaanniemi S,Rintamäki H,Jaakkola JJK,Ikäheimo TM

    更新日期:2019-05-09 00:00:00

  • Blood pressure control in the hypertension clinic.

    abstract:BACKGROUND:One effort to improve hypertension care in the United States is the development of the "Hypertension Specialist" program with appropriate training and certification of individual physicians. METHODS:We examined the impact of a hypertension clinic on blood pressure (BP) levels and control. RESULTS:By one ye...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Bansal N,Tendler BE,White WB,Mansoor GA

    更新日期:2003-10-01 00:00:00

  • Insulin resistance, glucose intolerance and hyperinsulinemia in patients with hypertension.

    abstract::Plasma glucose and insulin responses to an oral glucose challenge and insulin-stimulated glucose uptake were measured in 47 age-, weight-, and sex-matched lean white men (16 with normal blood pressure, 14 with untreated hypertension, nine treated with a thiazide diuretic only, and eight treated with combined diuretic ...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Swislocki AL,Hoffman BB,Reaven GM

    更新日期:1989-06-01 00:00:00

  • An in-depth examination of the excretion of albumin and other sensitive markers of renal damage in mild hypertension.

    abstract::In an in-depth examination to better define the renal effects of mild hypertension, we used urinary proteins to indicate damage to the glomerulus (albumin), tubular reabsorption capability (retinol-binding protein), and turnover of tubular tissue (alanine aminopeptidase and N-acetyl-beta-D-glucosaminidase) in a group ...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Mueller PW,Hall WD,Caudill SP,MacNeil ML,Arepally A

    更新日期:1995-11-01 00:00:00

  • Differences in effects of age and blood pressure on augmentation index.

    abstract:BACKGROUND:The effect of age on the augmentation index (AI) differs between young adults and the elderly, and the AI reaches a plateau after the age of 60 years. We examined whether the effects of age and an elevation in blood pressure on the AI differ between young adults and the elderly, between subjects with and wit...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Tomiyama H,Odaira M,Kimura K,Matsumoto C,Shiina K,Eguchi K,Miyashita H,Shimada K,Yamashina A

    更新日期:2014-12-01 00:00:00

  • Fixed-dose combination therapy with trandolapril and verapamil SR is effective in primary hypertension. Trandolapril Study Group.

    abstract::We assessed the efficacy of monotherapy with trandolapril, an angiotensin converting enzyme (ACE) inhibitor, and of verapamil slow-release (SR), a calcium antagonist, each in a range of three doses as monotherapy, and in the nine possible combinations of therapy in patients with stage I to III diastolic hypertension. ...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: DeQuattro V,Lee D

    更新日期:1997-07-01 00:00:00

  • The association of nephrolithiasis with hypertension and obesity: a review.

    abstract::Kidney stones affect hypertensive patients disproportionately compared to normotensive individuals. On the other hand, some prospective data suggest that a history of nephrolithiasis was associated with a greater tendency to develop hypertension. Newer epidemiologic data also link obesity and diabetes, features of the...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,评审


    authors: Obligado SH,Goldfarb DS

    更新日期:2008-03-01 00:00:00

  • Fibrinolytic/hemostatic variables in arterial hypertension: response to treatment with irbesartan or atenolol.

    abstract::Essential hypertension is often accompanied by abnormalities of the coagulation/fibrinolytic system, predisposing to a procoagulant state. The aim of the present study was to compare the effects of atenolol (beta1-blocker agent) and irbesartan (angiotensin II type 1 receptor antagonist) on plasma levels of hemostatic/...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章


    authors: Makris TK,Stavroulakis GA,Krespi PG,Hatzizacharias AN,Triposkiadis FK,Tsoukala CG,Votteas VV,Kyriakidis MK

    更新日期:2000-07-01 00:00:00

  • Nocturnal Intermittent Hypoxia Is Associated With Left Ventricular Hypertrophy in Middle-Aged Men With Hypertension and Obstructive Sleep Apnea.

    abstract:BACKGROUND:Obstructive sleep apnea (OSA) and left ventricular (LV) hypertrophy are considered to be closely associated. However, the relationship has not yet been fully demonstrated and is hence still controversial. The purpose of this study was to assess in hypertensive male patients the relationship between OSA and c...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Yamaguchi T,Takata Y,Usui Y,Asanuma R,Nishihata Y,Kato K,Shiina K,Yamashina A

    更新日期:2016-03-01 00:00:00