Salt-sensitive hypertension in conscious rats induced by chronic nitric oxide blockade.

abstract：BACKGROUND:The risk for cardiovascular events increases within hours of near-roadway exposures. We aimed to determine the traffic-related air pollution (TRAP) and biological mechanisms involved and if reducing particulate matter <2.5 µm (PM2.5) inhalation is protective. METHODS:Fifty healthy-adults underwent multiple ...

journal_title：American journal of hypertension

authors： Morishita M,Wang L,Speth K,Zhou N,Bard RL,Li F,Brook JR,Rajagopalan S,Brook RD

更新日期：2019-10-16 00:00:00

abstract：BACKGROUND:Hypertension is a risk factor for coronary heart disease (CHD), but the causes of hypertension remain largely unknown. Genetic variation is thought to contribute to the etiology of hypertension. We tested a single-nucleotide polymorphism (SNP) (Lys67Arg, rs197922) in the Golgi SNAP Receptor Complex Member 2 ...

journal_title：American journal of hypertension

authors： Meyer TE,Shiffman D,Morrison AC,Rowland CM,Louie JZ,Bare LA,Ross DA,Arellano AR,Chasman DI,Ridker PM,Pankow JS,Coresh J,Malloy MJ,Kane JP,Ellis SG,Devlin JJ,Boerwinkle E

更新日期：2009-02-01 00:00:00

abstract：:The aim of this study was to assess the contribution of physical activity levels to blood pressure (BP) variability, and to assess the effect age, gender, body mass index, and use of antihypertensive medications on this relationship. We simultaneously monitored 24-h ambulatory BP by automated recorder and activity by ...

journal_title：American journal of hypertension

authors： Leary AC,Donnan PT,MacDonald TM,Murphy MB

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Altered diastolic filling is an important contributor to several cardiovascular disorders. Multiple lines of evidence suggest a genetic contribution to left ventricular (LV) diastolic filling; however, chromosomal locations harboring genes involved in impaired LV diastolic filling have not been reported. The...

journal_title：American journal of hypertension

authors： Tang W,Arnett DK,Devereux RB,Atwood LD,Kitzman DW,Rao DC

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Clonidine, a centrally acting antihypertensive agent, has been used successfully in pregnancy. We sought to describe the pharmacodynamic effects of clonidine in pregnancy and the associated impact on fetal growth. METHODS:A retrospective cohort study was performed. Maternal hemodynamics were measured before...

journal_title：American journal of hypertension

authors： Rothberger S,Carr D,Brateng D,Hebert M,Easterling TR

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Postural change in systolic blood pressure (SBP) is prospectively associated with several disease outcomes including hypertension, stroke, and coronary heart disease. The objective of this study was to characterize further a possible quantitative trait locus on chromosome 18q21 influencing SBP response to a ...

journal_title：American journal of hypertension

authors： Pankow JS,Dunn DM,Hunt SC,Leppert MF,Miller MB,Rao DC,Heiss G,Oberman A,Lalouel JM,Weiss RB

更新日期：2005-05-01 00:00:00

abstract：:The protein chemerin (tazarotene-induced gene, TIG2; RARRES2) is a relatively new adipokine. Many studies support that circulating chemerin levels associate strongly and positively with body mass index, visceral fat, and blood pressure. Here, we focus on the specific relationship of chemerin and blood pressure with th...

journal_title：American journal of hypertension

authors： Ferland DJ,Mullick AE,Watts SW

更新日期：2020-11-03 00:00:00

abstract：:In normal coronary arteries, increased flow velocity induces endothelium-dependent dilation, and dilation in response to sympathetic stimulation evoked by the cold pressor test is partly due to increased flow velocity. In arterial hypertension, angiographically normal coronary arteries were constricted by acetylcholin...

journal_title：American journal of hypertension

authors： Nitenberg A,Antony I,Aptecar E,Arnoult F,Lerebours G

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Vitamin D deficiency in pregnancy has been associated with an increased risk of preeclampsia. However, the association between serum vitamin D and blood pressure in pregnant women has been scarcely evaluated, particularly in women with a high risk of developing hypertensive disorders of pregnancy. We sought ...

journal_title：American journal of hypertension

authors： Weinert LS,Reichelt AJ,Schmitt LR,Boff R,Oppermann ML,Camargo JL,Silveiro SP

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Parathyroid hormone (PTH) stimulates aldosterone secretion in human adrenocortex and is regulated by the renin-angiotensin-aldosterone system. We speculated that measurement of PTH may be a valuable aid in the diagnosis of aldosterone-producing adenoma (APA). METHODS:To test this hypothesis, we recruited 14...

journal_title：American journal of hypertension

authors： Zhang LX,Gu WJ,Li YJ,Wang Y,Wang WB,Wang AP,Shen L,Zang L,Yang GQ,Lu ZH,Dou JT,Mu YM

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:A modest rise in blood pressure (BP) reportedly increases cardiovascular mortality despite not reaching obvious hypertension, suggesting that target organ damages are latently induced by slight BP rising. The goal of this study was to determine whether presence of subclinical myocardial damage can predict th...

journal_title：American journal of hypertension

authors： Honda Y,Watanabe T,Tamura H,Nishiyama S,Takahashi H,Arimoto T,Shishido T,Miyamoto T,Shibata Y,Konta T,Kayama T,Kubota I

更新日期：2018-04-13 00:00:00

abstract：BACKGROUND:Matrix Gla protein (MGP) is a vascular calcification inhibitor dependent upon vitamin K for activation. Evidence suggests that elevated plasma inactive MGP levels (desphospho-uncarboxylated MGP, dp-ucMGP; indicating poorer vascular vitamin K status) are associated with greater cardiovascular disease (CVD) ri...

journal_title：American journal of hypertension

authors： Fain ME,Kapuku GK,Paulson WD,Williams CF,Raed A,Dong Y,Knapen MHJ,Vermeer C,Pollock NK

更新日期：2018-05-07 00:00:00

abstract：BACKGROUND:Pulse pressure (PP) is an independent predictor of cardiovascular and/or all-cause mortality in patients with underlying cardiovascular disease. We examined whether PP can be used to predict overall mortality in peritoneal dialysis (PD) patients. METHODS:We studied 153 PD patients (mean age, 54.5 +/- 14.2 y...

journal_title：American journal of hypertension

authors： Liu JH,Chen CC,Wang SM,Chou CY,Liu YL,Kuo HL,Lin HH,Wang IK,Yang YF,Huang CC

更新日期：2008-12-01 00:00:00

abstract：:This study was designed to clarify the relationship between the antihypertensive effects of the calcium antagonist nilvadipine, and circadian changes in blood pressure. Based on measurements using an ambulatory blood pressure monitoring system (ABPM), 17 outpatients with untreated essential hypertension were divided i...

journal_title：American journal of hypertension

authors： Yoshikawa H,Ohta A,Kasamatsu K,Ueno C,Funai H,Kuse S,Satani O,Nakamura N,Fukuda K,Hano T,Ueno Y,Nishio I,Iseki Y

更新日期：1998-01-01 00:00:00

abstract：:The influence of increased lability of blood pressure on the development of aortic atherosclerosis was examined. Because sinoaortic denervation (SAD) produced increased lability of blood pressure without blood pressure elevation, the development of atheromatous plaque was examined in SAD rats. These rats were fed a hi...

journal_title：American journal of hypertension

authors： Sasaki S,Yoneda Y,Fujita H,Uchida A,Takenaka K,Takesako T,Itoh H,Nakata T,Takeda K,Nakagawa M

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:The effect of age on the augmentation index (AI) differs between young adults and the elderly, and the AI reaches a plateau after the age of 60 years. We examined whether the effects of age and an elevation in blood pressure on the AI differ between young adults and the elderly, between subjects with and wit...

journal_title：American journal of hypertension

authors： Tomiyama H,Odaira M,Kimura K,Matsumoto C,Shiina K,Eguchi K,Miyashita H,Shimada K,Yamashina A

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:We compare patterns of blood pressure (BP) and prevalence of hypertension between white-Dutch and their South-Asian and African minority groups with their corresponding white-English and their South-Asian and African ethnic minority groups; and the contribution of physical activity, body sizes, and socioecon...

journal_title：American journal of hypertension

authors： Agyemang C,Kunst A,Bhopal R,Zaninotto P,Unwin N,Nazroo J,Nicolaou M,Redekop WK,Stronks K

更新日期：2010-06-01 00:00:00

abstract：:Our objective was to evaluate pretreatment predictors of longevity, particularly blood pressure, in a large cohort of hypertensive men. During 1974 to 1976, 10,367 male hypertensive veterans (47% black) were identified at screening and subsequently characterized in 32 special Veterans Administration (VA) hypertension ...

journal_title：American journal of hypertension

authors： Perry HM Jr,Miller JP,Baty JD,Carmody SE,Sambhi MP

更新日期：2000-06-01 00:00:00

abstract：:The ambulatory blood pressure load is generally defined as the proportion of elevated systolic or diastolic pressures over a 24 h period. This value represents the chronic pressure overload that induces myocardial and vascular damage associated with the hypertensive disease process. Blood pressure load has been define...

journal_title：American journal of hypertension

authors： White WB

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:The target levels of home-monitored blood pressure (BP) in patients with type 2 diabetes mellitus (T2DM) have not yet been established. We sought to examine the appropriate target home BP level in T2DM. METHODS:This is a subanalysis of the Japan Morning Surge-Home Blood Pressure (J-HOP) study. We enrolled 4,...

journal_title：American journal of hypertension

authors： Eguchi K,Hoshide S,Komori T,Nagasaka S,Kario K

更新日期：2015-08-01 00:00:00

abstract：:The current study tested the hypothesis that centrally administered relaxin elevates arterial pressure in conscious rats and that this hypertensive effect is mediated, at least in part, by central or peripheral vasopressin. Injection of human relaxin (0.068 or 0.34 microgram in 200 nL artificial cerebrospinal fluid) i...

journal_title：American journal of hypertension

authors： Yang RH,Bunting S,Wyss JM,Berecek KH,Zhang L,Jin H

更新日期：1995-04-01 00:00:00

abstract：:This study was designed to analyze the cardiac effects of aging and of hypertension in patients with essential hypertension and with or without left ventricular hypertrophy (LVH). Thirty-one patients <55 years old and 66 patients >64 years old with essential hypertension were divided according to the presence or absen...

journal_title：American journal of hypertension

authors： Grodzicki T,Michalewicz L,Messerli FH

更新日期：1998-04-01 00:00:00

abstract：:High affinity Ca2(+)-activated, Mg2(+)-dependent ATP-ase [Ca2+ + Mg2+)-ATPase) activities were characterized in the membrane fractions of the porcine aorta. The (Ca2+ + Mg2+)-ATPase activity, similar to those found in the plasma membranes of the erythrocyte and the heart, ie, Ca2(+)-pumping ATPase activity, was not fo...

journal_title：American journal of hypertension

authors： Yoshida Y,Sun HT,Imai S

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Hypertension is a significant global public health challenge. Low-grade inflammation is known to facilitate the development of essential hypertension and target-organ hypertensive damage. Neutrophil to lymphocyte ratio (NLR) is a simple and reliable indicator of inflammation that may also be useful in the pr...

journal_title：American journal of hypertension

authors： Liu X,Zhang Q,Wu H,Du H,Liu L,Shi H,Wang C,Xia Y,Guo X,Li C,Bao X,Su Q,Sun S,Wang X,Zhou M,Jia Q,Zhao H,Song K,Niu K

更新日期：2015-11-01 00:00:00

abstract：:Recent works have shown the importance of blood pressure (BP) response to exercise or to daily activity as determinants of hypertensive cardiac hypertrophy. We have tested the relationship between BP and left ventricular (LV) mass in 23 normotensive young adults (mean age 25 +/- 5) with normotensive parents. Blood pre...

journal_title：American journal of hypertension

authors： Gosse P,Desrumeau GC,Roudaut R,Broustet JP,Dallocchio M

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Blood pressure is a complex quantitative trait with a strong genetic component. In this study, we leveraged the Veterans Affairs electronic medical record system to explore the relationship between Paraoxonase 1 (PON1)-108 C/T (rs705379) and mean arterial blood pressure (MAP). METHODS:Outpatient blood press...

journal_title：American journal of hypertension

authors： Bhatnagar V,Liu L,Nievergelt CM,Richard E,Brophy VH,Pandey B,Lipkowitz MS,O'Connor DT

更新日期：2012-11-01 00:00:00

abstract：:There is evidence that hyperinsulinemia and insulin resistance play a role in the development of hypertension. Accordingly, in our ongoing longitudinal study of pregnancy-induced hypertension, we have measured fasting levels of insulin and glucose at 18 to 25 weeks gestation in 140 nulliparous African-American women f...

journal_title：American journal of hypertension

authors： Sowers JR,Saleh AA,Sokol RJ

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:In experimental renovascular hypertension, aldosterone has been implicated in myocardial remodeling and fibrosis, but it is uncertain whether excess aldosterone effects left ventricular structure and function in hypertensive patients. METHODS:Hypertensive patients from the Cardiovascular Center of the New Y...

journal_title：American journal of hypertension

authors： Goldkorn R,Yurenev A,Blumenfeld J,Fishman D,Devereux RB

更新日期：2002-04-01 00:00:00

abstract：:Endothelin-1 is a potent vasoconstrictor peptide produced in blood vessels and other tissues that may play an important role in the control of local blood flow and could be involved in the pathogenesis of hypertension. Our previous studies have documented increases in endothelin-1 peptide content and gene expression i...

journal_title：American journal of hypertension

authors： Day R,Larivière R,Schiffrin EL

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Hypertension guidelines recommend home blood pressure monitoring (HBPM) to help achieve blood pressure (BP) control. We hypothesized that HBPM use with a physician recommendation would be associated with lower BP and greater medication adherence. METHODS:We used data from 6,320 adults with hypertension in t...

journal_title：American journal of hypertension

authors： Tang O,Foti K,Miller ER,Appel LJ,Juraschek SP

更新日期：2020-09-10 00:00:00