Further evidence of a quantitative trait locus on chromosome 18 influencing postural change in systolic blood pressure: the Hypertension Genetic Epidemiology Network (HyperGEN) Study.

abstract：:Although left ventricular hypertrophy (LVH) is an adaptive response to the increased load imposed on the heart in patients with hypertension, it ultimately is itself a major risk factor for cardiovascular disease. The influence of LVH on left ventricular function and on the coronary circulation, and the occurrence of ...

journal_title：American journal of hypertension

authors： Clement DL,De Buyzere M,Duprez D

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:The present study examined the inhibitory action of temporary treatment with an angiotensin type 1 (AT(1)) receptor blocker (ARB) on vascular remodeling using hypertensive mice with overexpression of the human renin (hRN) and angiotensinogen (hANG) genes. METHODS:hRN/hANG transgenic mice (hRN/hANG-Tg) were ...

journal_title：American journal of hypertension

authors： Inaba S,Iwai M,Furuno M,Kanno H,Senba I,Okayama H,Mogi M,Higaki J,Horiuchi M

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:The association of adiposity during childhood with future risk of elevated blood pressure (BP) in South Asian children is not known. We aimed to investigate the relationship between waist circumference (WC) and body mass index (BMI) with BP over a 2-year period, independent of the baseline BP. METHODS:We an...

journal_title：American journal of hypertension

authors： Almas A,Jafar TH

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Nocturnal blood pressure (BP) is associated with risk for cardiovascular events. However, the relationship between nocturnal BP in young adults and cognitive function in midlife remains unclear. METHODS:We used data from the ambulatory BP monitoring substudy of the Coronary Artery Risk Development in Young ...

journal_title：American journal of hypertension

authors： Yano Y,Ning H,Muntner P,Reis JP,Calhoun DA,Viera AJ,Levine DA,Jacobs DR Jr,Shimbo D,Liu K,Greenland P,Lloyd-Jones D

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:The renin-angiotensin system (RAS) plays a major role in promoting left ventricular (LV) remodeling in essential hypertension. We designed a controlled, randomized pilot study aimed to test the hypothesis that the dual RAS blockade with angiotensin-converting enzyme (ACE) inhibitor (ACEi) + angiotensin II re...

journal_title：American journal of hypertension

authors： Grandi AM,Solbiati F,Laurita E,Maresca AM,Nicolini E,Marchesi C,Gianni M,Guasti L,Venco A

更新日期：2008-02-01 00:00:00

abstract：:The renin-angiotensin-aldosterone system plays a major role in the pathogenesis of hypertension by enhancing the production or the activity of angiotensin II (ANG II). We evaluated the effects of hormone replacement therapy (HRT) on the renin-angiotensin-aldosterone system and on bradykinin in postmenopausal women (PM...

journal_title：American journal of hypertension

authors： Umeda M,Ichikawa S,Kanda T,Sumino H,Kobayashi I

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) induces inflammation and vascular damage that might contribute to an increased risk of cardiovascular disease (CVD). However, the mechanisms linking OSA and CVD are not fully understood. Pentraxin3 may play a significant role in vascular inflammation and damage. Currently, there...

journal_title：American journal of hypertension

authors： Kasai T,Inoue K,Kumagai T,Kato M,Kawana F,Sagara M,Ishiwata S,Ohno M,Yamaguchi T,Momomura S,Narui K

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Genetic factors may influence blood pressure (BP) responses to dietary potassium intake. We examined the association of genetic variants in the apelin-APJ system and angiotensin-converting enzyme 2 (ACE2) with BP responses to potassium supplementation. METHODS:We conducted a 7-day potassium supplementation ...

journal_title：American journal of hypertension

authors： Zhao Q,Gu D,Kelly TN,Hixson JE,Rao DC,Jaquish CE,Chen J,Huang J,Chen CS,Gu CC,Whelton PK,He J

更新日期：2010-06-01 00:00:00

abstract：:Apart from the well-known role of hypertension in cerebrovascular disease, visit-to-visit blood pressure (BP) variability is emerging as an independent risk factor for stroke. Although the underlying mechanism is not fully understood, artery remodeling is thought to be closely involved in the relationship between visi...

journal_title：American journal of hypertension

authors： Nagai M,Kario K

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Hypertension presents high prevalence rates following kidney transplantation (Tx). The aims of the present study were to investigate the prevalence and possible risk factors for hypertension and blood pressure (BP) control over time after pediatric kidney Tx, as well as to assess possible effects of hyperten...

journal_title：American journal of hypertension

authors： Stabouli S,Printza N,Dotis J,Gkogka C,Kollios K,Kotsis V,Papachristou F

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:There is an association between maternal body mass index (BMI) and preeclampsia, but if BMI has an effect on preeclampsia of all severities is debated. If there is an association between maternal height and preeclampsia of all severities is unknown. METHODS:In this population-based cohort study including 50...

journal_title：American journal of hypertension

authors： Sohlberg S,Stephansson O,Cnattingius S,Wikström AK

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C) are risk factors for coronary artery disease (CAD) and ischemic stroke. However, the hazards of their coexistence are not fully understood in Asian populations. We investigated whether the relationship between BP and cardiovascular disease (...

journal_title：American journal of hypertension

authors： Tsukinoki R,Okamura T,Watanabe M,Kokubo Y,Higashiyama A,Nishimura K,Takegami M,Murakami Y,Okayama A,Miyamoto Y

更新日期：2014-11-01 00:00:00

abstract：:Insulin acutely inhibits contraction of primary cultured vascular smooth muscle (VSM) cells from canine femoral artery by inhibiting contractile agonist-induced Ca2+ influx. Insulin also inhibits contraction at step(s) distal to intracellular Ca2+ concentration (Ca2+i) by stimulating cyclic guanosine monophosphate (GM...

journal_title：American journal of hypertension

authors： Kahn AM,Allen JC,Seidel CL,Song T

更新日期：2000-04-01 00:00:00

abstract：:The most common reason for an outpatient physician visit is for the diagnosis and treatment of hypertension. The Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC) VII, which is increasingly evidence-based, advises the clinician to use studies of the mean response...

journal_title：American journal of hypertension

authors： Graves JW,Sheps SG

更新日期：2004-04-01 00:00:00

abstract：:This study found that pigs in the early stages of perinephritic hypertension had enhanced plasma norepinephrine (NE) and heart rate (HR) responses to behaviorally arousing stimuli (lifting in a canvas sling) and exercise. In the hypertensive animals, the increase in plasma NE in response to behavioral arousal caused b...

journal_title：American journal of hypertension

authors： Zhao S,Pinto JM,Bergau D,Lown B,Kirby DA

更新日期：1993-10-01 00:00:00

abstract：:Endothelin-1 is a potent vasoconstrictor peptide produced in blood vessels and other tissues that may play an important role in the control of local blood flow and could be involved in the pathogenesis of hypertension. Our previous studies have documented increases in endothelin-1 peptide content and gene expression i...

journal_title：American journal of hypertension

authors： Day R,Larivière R,Schiffrin EL

更新日期：1995-03-01 00:00:00

abstract：:There is evidence that hyperinsulinemia and insulin resistance play a role in the development of hypertension. Accordingly, in our ongoing longitudinal study of pregnancy-induced hypertension, we have measured fasting levels of insulin and glucose at 18 to 25 weeks gestation in 140 nulliparous African-American women f...

journal_title：American journal of hypertension

authors： Sowers JR,Saleh AA,Sokol RJ

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Altered diastolic filling is an important contributor to several cardiovascular disorders. Multiple lines of evidence suggest a genetic contribution to left ventricular (LV) diastolic filling; however, chromosomal locations harboring genes involved in impaired LV diastolic filling have not been reported. The...

journal_title：American journal of hypertension

authors： Tang W,Arnett DK,Devereux RB,Atwood LD,Kitzman DW,Rao DC

更新日期：2002-07-01 00:00:00

abstract：:The aim of this study was to evaluate the delayed effects of an angiotensin converting enzyme (ACE) inhibitor on blood pressure and on structural and functional alterations in mesenteric small resistance arteries of spontaneously hypertensive rats (SHR). The ACE inhibitor fosinopril (25 mg/kg/day) was administered acc...

journal_title：American journal of hypertension

authors： Rizzoni D,Castellano M,Porteri E,Bettoni G,Muiesan ML,Cinelli A,Zulli R,Rosei EA

更新日期：1997-09-01 00:00:00

abstract：:The objective of this study was to test the relationship between neurologic and microvascular complications of type 1 diabetes mellitus. It was hypothesized that the mechanisms operative in autonomic dysfunction seen in diabetic patients with microangiopathy play a role in the rapidity of progression to renal failure....

journal_title：American journal of hypertension

authors： Weinrauch LA,Kennedy FP,Gleason RE,Keough J,D'Elia JA

更新日期：1998-03-01 00:00:00

abstract：:The present study was designed to investigate the role of the autonomic nervous system in experimental hypertension induced by chronic administration of N-nitro-L-arginine methyl ester (L-NAME) in the drinking water (1 mg/mL) over 6 days. L-NAME ingestion caused a large rise in resting mean arterial pressure (MAP) (17...

journal_title：American journal of hypertension

authors： Cunha RS,Cabral AM,Vasquez EC

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Experimentally induced sleep deprivation can raise blood pressure (BP) and worsen hypertension. We recently reported a significantly higher prevalence of obstructive sleep apnea (OSA) and reduced rapid eye movement (REM) sleep time in drug-resistant hypertensives compared to controlled hypertensives. The obj...

journal_title：American journal of hypertension

authors： Friedman O,Bradley TD,Ruttanaumpawan P,Logan AG

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The reduction of coronary flow reserve (CFR) found in arterial hypertension may be due to changes in afterload, left ventricular (LV) structure, and metabolic factors. Also, insulin-like growth factor-1 (IGF-1) may be associated with the magnitude of CFR in relation to its modulating action on cardiac and en...

journal_title：American journal of hypertension

authors： Galderisi M,Caso P,Cicala S,De Simone L,Barbieri M,Vitale G,de Divitiis O,Paolisso G

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Substantial epidemiological evidence documents diverse health benefits, including reduced risks of hypertension, associated with diets high in fiber. Few studies, however, have investigated the extent to which dietary fiber intake in early pregnancy is associated with reductions in preeclampsia risk. We asse...

journal_title：American journal of hypertension

authors： Qiu C,Coughlin KB,Frederick IO,Sorensen TK,Williams MA

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Feeding stroke-prone spontaneously hypertensive rats (SHRSP) a diet rich in fructose results in a profound glucose intolerance not observed in the normotensive Wistar Kyoto (WKY) strain. The aim of this study was to investigate the role of the liver in the underlying mechanisms in the SHRSP. METHODS:SHRSP a...

journal_title：American journal of hypertension

authors： Brosnan MJ,Carkner RD

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Although several characteristics of aortic function, which are largely determined by age, predict outcomes beyond brachial blood pressure (BP), the extent to which brachial BP control accounts for age-related variations in aortic function is uncertain. We aimed to determine the extent to which brachial BP co...

journal_title：American journal of hypertension

authors： Hodson B,Norton GR,Booysen HL,Sibiya MJ,Raymond A,Maseko MJ,Majane OH,Libhaber E,Sareli P,Woodiwiss AJ

更新日期：2016-05-01 00:00:00

abstract：:We assessed the efficacy of monotherapy with trandolapril, an angiotensin converting enzyme (ACE) inhibitor, and of verapamil slow-release (SR), a calcium antagonist, each in a range of three doses as monotherapy, and in the nine possible combinations of therapy in patients with stage I to III diastolic hypertension. ...

journal_title：American journal of hypertension

authors： DeQuattro V,Lee D

更新日期：1997-07-01 00:00:00

abstract：:Echocardiography (ECHO) is useful to document changes in left ventricular mass (LVM) in groups of patients, but may be too variable for use in the individual patient. Magnetic resonance imaging (MRI) may be a more precise and reliable method to quantify the mass of the left ventricule. This study reports the accuracy,...

journal_title：American journal of hypertension

authors： Bottini PB,Carr AA,Prisant LM,Flickinger FW,Allison JD,Gottdiener JS

更新日期：1995-03-01 00:00:00

abstract：:The ambulatory blood pressure load is generally defined as the proportion of elevated systolic or diastolic pressures over a 24 h period. This value represents the chronic pressure overload that induces myocardial and vascular damage associated with the hypertensive disease process. Blood pressure load has been define...

journal_title：American journal of hypertension

authors： White WB

更新日期：1996-10-01 00:00:00

abstract：:Blood pressure is reportedly elevated in the spontaneously hypertensive rat (SHR) neonate, the etiology of which remains unclear. Aberrations in the hypothalamic-pituitary-adrenal axis have been implicated, as it is well accepted that excess corticosteroids are associated with hypertension. We examined aspects of adre...

journal_title：American journal of hypertension

authors： Malee MP,Wu KY

更新日期：1999-05-01 00:00:00