Atrial natriuretic factor potentiating and hemodynamic effects of SCH 42495, a new, neutral metalloendopeptidase inhibitor.

abstract：:The renin content, expressed as nanograms of angiotensin I/hour/milligram, of a rabbit intrarenal arterial network (IAN) was compared to that of renal cortical samples from the same animal. Tissues from six rabbits were studied. Cortical tissue (RC) and an IAN with some glomeruli and attached arterioles (IAN + glomeru...

journal_title：American journal of hypertension

authors： Birt PC,Zimmerman BG

更新日期：1995-04-01 00:00:00

abstract：:Cardiovascular diseases (CVD) are the major causes of mortality in persons with diabetes, and many factors, including hypertension, contribute to this high prevalence of CVD. The incidence of hypertension in patients with diabetes is approximately twofold higher than in age-matched subjects without the disease, and co...

journal_title：American journal of hypertension

authors： Sowers JR

更新日期：2003-11-01 00:00:00

abstract：:Stroke (brain attack) is currently the third leading cause of death in Western societies. Recent advances in molecular genetics have finally demonstrated what has long been suggested by the clinical observation, that is, stroke is not only the complication of major pathologic conditions such as atherosclerosis, hypert...

journal_title：American journal of hypertension

authors： Rubattu S,Giliberti R,Volpe M

更新日期：2000-10-01 00:00:00

abstract：:Reversible posterior leukoencephalopathy syndrome (RPLS) is an uncommon entity related to multiple and different pathologies, the most common being hypertensive crisis. It is believed to be secondary to the breakdown on the blood-brain barrier. At the beginning, it is undistinguishable from other leukoencephalopathies...

journal_title：American journal of hypertension

authors： Giner V,Fernández C,Esteban MJ,Galindo MJ,Forner MJ,Guix J,Redón J

更新日期：2002-05-01 00:00:00

abstract：:In this review we have analyzed the present knowledge about the differentiation and growth processes in vascular smooth muscle cells (SMC) in hypertension. The study of smooth muscle (SM) and nonmuscle (NM) myosin isoform expression has permitted us to identify a three-stage specific maturational pathway, namely, feta...

journal_title：American journal of hypertension

authors： Pauletto P,Sarzani R,Rappelli A,Chiavegato A,Pessina AC,Sartore S

更新日期：1994-07-01 00:00:00

abstract：:Blood pressure responses to 1 week of low (20 mmol sodium/day) and high (300 mmol sodium/day) salt intake were investigated in a double-blind, randomized study in 46 white, nonobese subjects with essential hypertension (13 women, 33 men; mean age 45.3 +/- 2.2 years, age range 25 to 80 years). The individuals were clas...

journal_title：American journal of hypertension

authors： Overlack A,Ruppert M,Kolloch R,Kraft K,Stumpe KO

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Overweight/obese young men have increased sympatho-excitation to cold and pain stress-induced by the cold pressor test (CPT) that may lead to abnormal hemodynamic responses. Concurrent CPT and exercise may augment the sympathetic-induced increases in aortic blood pressure (BP), pressure wave reflection (augm...

journal_title：American journal of hypertension

authors： Kalfon R,Campbell J,Alvarez-Alvarado S,Figueroa A

更新日期：2015-11-01 00:00:00

abstract：:There is evidence that hyperinsulinemia and insulin resistance play a role in the development of hypertension. Accordingly, in our ongoing longitudinal study of pregnancy-induced hypertension, we have measured fasting levels of insulin and glucose at 18 to 25 weeks gestation in 140 nulliparous African-American women f...

journal_title：American journal of hypertension

authors： Sowers JR,Saleh AA,Sokol RJ

更新日期：1995-01-01 00:00:00

abstract：:To evaluate the reactivity to psychological stress in patients with essential hypertension we investigated hemodynamic and endocrinologic changes during a mental arithmetic task (MAT) and a mirror drawing test (MDT) in 10 hypertensive subjects. Hemodynamic changes were assessed continuously using an ambulatory radionu...

journal_title：American journal of hypertension

authors： Yoshiuchi K,Nomura S,Ando K,Ohtake T,Shimosawa T,Kumano H,Kuboki T,Suematsu H,Fujita T

更新日期：1997-03-01 00:00:00

abstract：:The relationship between erythrocyte cation transport systems and membrane and plasma lipids was examined in normal men and patients with insulin-dependent diabetes mellitus (IDDM). Different measurements of erythrocyte transport systems were obtained in patients with IDDM and in age- and weight-matched healthy men: N...

journal_title：American journal of hypertension

authors： Lijnen P,Fenyvesi A,Bex M,Bouillon R,Amery A

更新日期：1993-09-01 00:00:00

abstract：:The aim of this study was to compare sexual activity and plasma testosterone levels of hypertensive men with those of healthy normotensive controls. We investigated 110 newly diagnosed, never treated hypertensive (blood pressure [BP] > or = 140/95 mm Hg) men and 110 healthy normotensive (diastolic BP <90 mm Hg) men. A...

journal_title：American journal of hypertension

authors： Fogari R,Zoppi A,Preti P,Rinaldi A,Marasi G,Vanasia A,Mugellini A

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:High salt diet causes cardiac hypertrophy and fibrosis and increases cardiac aldosterone, while decreasing plasma aldosterone. The present study assessed, in Wistar rats, the effect of high salt diet on left and right ventricle (LV and RV, respectively) weight and fibrosis both with and without the aldostero...

journal_title：American journal of hypertension

authors： Lal A,Veinot JP,Leenen FH

更新日期：2003-04-01 00:00:00

abstract：:Antihypertensive treatment is known to slow down the decline in glomerular filtration rate (GFR) with time. Angiotensin converting enzyme (ACE) inhibition has been shown to be more effective in this regard than conventional antihypertensive therapy. In a recent prospective, randomized, double blind trial in 257 patien...

journal_title：American journal of hypertension

authors： Himmelmann A,Hansson L,Hansson BG,Hedstrand H,Skogström K,Ohrvik J,Furängen A

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Low birth weight has been associated with increased risk of hypertension later in life. The aim of this study was to evaluate the association between birth weight and blood pressure (BP) in healthy 9- to 10-year-old Icelandic children. METHODS:Each child underwent 4 seated BP measurements, and the BP percen...

journal_title：American journal of hypertension

authors： Steinthorsdottir SD,Eliasdottir SB,Indridason OS,Palsson R,Edvardsson VO

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Obesity has been described as a predictor of cardiovascular mortality, and some studies have reported an association with obesity and increased aortic stiffness. Other studies have not identified obesity to be an independent risk factor. Therefore, the purpose of our study was to determine the association be...

journal_title：American journal of hypertension

authors： Rodrigues SL,Baldo MP,Lani L,Nogueira L,Mill JG,Sa Cunha Rd

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Ionized magnesium levels are elevated in fetal blood compared with maternal blood, suggesting that the placenta may possess an active transport mechanism for magnesium. In the present study, we sought to determine the existence of an active transport mechanism for magnesium in the placenta using cultured tro...

journal_title：American journal of hypertension

authors： Standley PR,Standley CA

更新日期：2002-06-01 00:00:00

abstract：:A colony of genetic hypertensive dogs with systolic blood pressure of 140 to 220 mm Hg and diastolic blood pressure greater than 100 mm Hg in the trained state was used. The objective of this study was to investigate the hemodynamic and renal effects of the novel angiotensin II receptor antagonist DuP 753 given intrav...

journal_title：American journal of hypertension

authors： Bovee KC,Wong PC,Timmermans PB,Thoolen MJ

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Left ventricular hypertrophy (LVH) is an independent risk factor for cardiovascular morbidity in hypertension. Current evidence suggests a contribution to LVH of plasma aldosterone levels that are inappropriately elevated for the salt status. The aim of this study was to investigate whether inappropriate mod...

journal_title：American journal of hypertension

authors： Catena C,Verheyen ND,Url-Michitsch M,Kraigher-Krainer E,Colussi G,Pilz S,Tomaschitz A,Pieske B,Sechi LA

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The brain is perfused at high-volume flow throughout systole and diastole. We explored the association of blood flow in the middle cerebral artery (MCA) with the pulsatile components of blood pressure in the systemic circulation and indices of arterial stiffness. METHODS:We enrolled 334 untreated subjects (...

journal_title：American journal of hypertension

authors： Xu TY,Staessen JA,Wei FF,Xu J,Li FH,Fan WX,Gao PJ,Wang JG,Li Y

更新日期：2012-03-01 00:00:00

abstract：:It is known that calcium induces the formation of potent vasodilators in endothelial cells and vasoconstriction in smooth muscle cells, whereas in the renal parenchyma, it modulates sodium excretion through vascular and tubular mechanisms. Consequently, an increased concentration of calcium in renal circulation may in...

journal_title：American journal of hypertension

authors： Lahera V,Ruilope LM,Romero JC

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Masked hypertension (MHT), defined as normal blood pressure (BP) at office associated with high BP at home, has been shown to be associated with an increased risk of vascular events. However, MHT is poorly known in the elderly, although this age segment is at high risk of hypertension-related vascular events...

journal_title：American journal of hypertension

authors： Cacciolati C,Hanon O,Alpérovitch A,Dufouil C,Tzourio C

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Although previous studies have explored the effect of smoking on blood pressure, little is still known about the role of time to first cigarette (TTFC)-an indicator of nicotine dependence-in hypertension. Therefore, we evaluated this association using representative nationwide data. METHODS:Current daily sm...

journal_title：American journal of hypertension

authors： Bae J,Yi YH,Kim YJ,Lee JG,Tak YJ,Lee SH,Hwang HR,Lee SY,Cho YH,Ro EJ

更新日期：2019-01-15 00:00:00

abstract：BACKGROUND:The risk for cardiovascular events increases within hours of near-roadway exposures. We aimed to determine the traffic-related air pollution (TRAP) and biological mechanisms involved and if reducing particulate matter <2.5 µm (PM2.5) inhalation is protective. METHODS:Fifty healthy-adults underwent multiple ...

journal_title：American journal of hypertension

authors： Morishita M,Wang L,Speth K,Zhou N,Bard RL,Li F,Brook JR,Rajagopalan S,Brook RD

更新日期：2019-10-16 00:00:00

abstract：:Nitric oxide synthase (NOS) blockade increases blood pressure (BP) and modifies glomerular and tubular function. Angiotensin II (AII) blockade restores glomerular and tubular function but does not lower BP. We measured plasma renin activity (PRA), plasma (AIIp), and kidney tissue (AIIk) AII with radioimmunoassay to in...

journal_title：American journal of hypertension

authors： Garcia GE,Brown MR,Wead LM,Braun S,Gabbai FB

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:An increasing number of arterial function assessments are available, including small and large arterial elasticity (SAE/C2, LAE/C1), endothelial function as measured by flow mediated dilation (FMD), carotid intima-medial thickness (IMT), ankle brachial index (ABI), pulse pressure (PP), and pulse wave velocit...

journal_title：American journal of hypertension

authors： Wilson AM,O'Neal D,Nelson CL,Prior DL,Best JD,Jenkins AJ

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:The "nondipping" pattern (NDP) of blood pressure, characterized by the absence of the reduction in blood pressure (BP) that typically takes place during the night time, has been associated with elevated cardiovascular morbidity, including stroke, myocardial infarction, and sudden cardiac-related death. In va...

journal_title：American journal of hypertension

authors： Myredal A,Friberg P,Johansson M

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:We evaluated the relationship of the severity of hyperuricemia and the flow-mediated vasodilatation of the brachial artery (FMD) in patients with and without the metabolic syndrome (MetS). METHODS:In a cross-sectional study, FMD was obtained in 2,732 Japanese healthy men (49 ± 8 years) who had no cardiovasc...

journal_title：American journal of hypertension

authors： Tomiyama H,Higashi Y,Takase B,Node K,Sata M,Inoue T,Ishibashi Y,Ueda S,Shimada K,Yamashina A

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Schlager inbred hypertensive mice (BPH/2J) have been suggested to have high blood pressure (BP) due to an overactive sympathetic nervous system (SNS). The brain nuclei associated with the hypertension are also those involved in the integration of the cardiovascular responses to stress. Therefore, in the pres...

journal_title：American journal of hypertension

authors： Davern PJ,Jackson KL,Nguyen-Huu TP,La Greca L,Head GA

更新日期：2010-08-01 00:00:00

abstract：:Recent publications purporting to show that calcium antagonists, when used for the treatment of hypertension or in the post myocardial infarction patient, would paradoxically increase the rate of heart attack and mortality have cast doubts on the safety and efficacy of this drug class. All three studies are retrospect...

journal_title：American journal of hypertension

authors： Messerli FH

更新日期：1996-12-01 00:00:00

abstract：:The peak incidence of cardiovascular complications in the morning points to a possible role of the abrupt increase in blood pressure on arising. However, there is as yet no firm evidence linking the extent of the elevation in blood pressure on arising and the risk of cardiovascular complications. We sought a correlati...

journal_title：American journal of hypertension

authors： Gosse P,Ansoborlo P,Lemetayer P,Clementy J

更新日期：1997-05-01 00:00:00