Intrarenal arterial network renin content and inhibition by EMD 58265.

abstract：:Ca2+ efflux from cultured vascular smooth muscle cells (VSMC) consists of two mechanisms: one is dependent on extracellular sodium, mediated by the Na(+)-Ca2+ exchange (Na+o-dependent Ca2+ efflux), and the other is independent of extracellular sodium but is mediated by the Ca(2+)-pump (Na+o-independent Ca2+ efflux). I...

journal_title：American journal of hypertension

authors： Chen S,Roufogalis BD

更新日期：1994-07-01 00:00:00

abstract：:Twenty-four-hour ambulatory blood pressure measurements (ABPM) are likely to eliminate the stress of visits and observer bias in office blood pressure (BP) recordings, allow consideration of the circadian variability in BP, and correlate well with target organ damage. To define the prevalence of "white coat" hypertens...

journal_title：American journal of hypertension

authors： Khoury S,Yarows SA,O'Brien TK,Sowers JR

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:This study investigated the relationship of ethnicity to the differences between blood pressure (BP) measured in a clinic setting and by ambulatory blood pressure monitoring (ABPM) in individuals with a previous diagnosis of hypertension (HT) and without a previous diagnosis of hypertension (NHT). METHODS:A...

journal_title：American journal of hypertension

authors： Martin U,Haque MS,Wood S,Greenfield SM,Gill PS,Mant J,Mohammed MA,Heer G,Johal A,Kaur R,Schwartz C,McManus RJ

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Carvedilol is known to be an adrenoreceptor blocker and free radical scavenger, used in hypertension and cardiac failure. However, its therapeutic actions cannot be fully explained by these mechanisms. In these studies, we tested the hypothesis that carvedilol action is associated with the synthesis/release ...

journal_title：American journal of hypertension

authors： Afonso RA,Patarrao RS,Macedo MP,Carmo MM

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Our aim was to assess whether home blood pressure (HBP) and ambulatory BP monitoring measurement (ABPM), in addition to office BP (OBP) predict changes of cardiovascular biomarkers during antihypertensive treatment. METHODS:Two hundred and fifty-two hypertensive patients (mean age, 68 years; men: 41%) under...

journal_title：American journal of hypertension

authors： Yano Y,Hoshide S,Shimizu M,Eguchi K,Ishikawa J,Ishikawa S,Shimada K,Kario K

更新日期：2012-03-01 00:00:00

abstract：:High levels of plasma homocyst(e)ine (H[e]) are associated with increased vascular risk. Treatment is being contemplated, but the level at which patients should be treated is not known. We compared the response of carotid plaque to vitamin therapy in patients with H(e) above and below 14 micromol/L, a level commonly r...

journal_title：American journal of hypertension

authors： Hackam DG,Peterson JC,Spence JD

更新日期：2000-01-01 00:00:00

abstract：:To evaluate the clinical importance of serum hepatocyte growth factor (HGF) concentration, we designed two clinical investigations. The first study analyzed the correlation between serum HGF concentration and clinical arterial stiffness or the vasodilator response to reactive hyperemia in hypertensive patients. The se...

journal_title：American journal of hypertension

authors： Komai N,Ohishi M,Morishita R,Moriguchi A,Kaibe M,Matsumoto K,Rakugi H,Higaki J,Ogihara T

更新日期：2002-06-01 00:00:00

abstract：:The purpose of this study was to determine whether there are gender differences in plasma insulin levels or insulin resistance in young adult African-Americans. Male (n = 53) and female (n = 45) subjects (age 23 to 28 years) included normotensives (N, blood pressure [BP] < 135/85 mm Hg) and borderline hypertensives (B...

journal_title：American journal of hypertension

authors： Falkner B,Hulman S,Kushner H

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Reactive oxygen species play a key role in the formation of endothelial dysfunction accompanying diabetes mellitus, hypertension, and other cardiovascular diseases. METHOD:This study compares oxidative stress (OS) in Wistar-Kyoto rats (WKY), spontaneously hypertensive rats (SHR), non-insulin-dependent Cohen...

journal_title：American journal of hypertension

authors： Friedman J,Peleg E,Kagan T,Shnizer S,Rosenthal T

更新日期：2003-12-01 00:00:00

abstract：:Since we and others have found a decrease in intestinal Ca2+ absorption and renal Ca2+ reabsorption in the mature spontaneously hypertensive rat (SHR) at the tissue and cell level, we asked whether the transport defect was located at the luminal or the basolateral side of the epithelial cell. We studied intestinal and...

journal_title：American journal of hypertension

authors： Hennessen U,Chabanis S,Silva SL,Nabarra B,Drüeke T,Lacour B

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:The brain is perfused at high-volume flow throughout systole and diastole. We explored the association of blood flow in the middle cerebral artery (MCA) with the pulsatile components of blood pressure in the systemic circulation and indices of arterial stiffness. METHODS:We enrolled 334 untreated subjects (...

journal_title：American journal of hypertension

authors： Xu TY,Staessen JA,Wei FF,Xu J,Li FH,Fan WX,Gao PJ,Wang JG,Li Y

更新日期：2012-03-01 00:00:00

abstract：:Vasoconstrictor and Na/K pump inhibitory properties of a bufodienolide Na/K-ATPase inhibitor, marinobufagenin, were studied in isolated rings of 2 to 3 order branches of human pulmonary arteries respectively. Marinobufagenin displayed concentration-dependent vasoconstrictor activity (0.01 to 10 mmol/L). In sarcolemma ...

journal_title：American journal of hypertension

authors： Bagrov AY,Dmitrieva RI,Fedorova OV,Kazakov GP,Roukoyatkina NI,Shpen VM

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Sleep apnea is being studied as a risk factor for hypertension. This observational chart review was conducted to determine the long-term effects of continuous positive airway pressure (CPAP) treatment on blood pressure (BP) in a sample of sleep apnea patients from urban and rural populations. METHODS:This s...

journal_title：American journal of hypertension

authors： Dhillon S,Chung SA,Fargher T,Huterer N,Shapiro CM

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:It is not clear which educational strategy is most effective in helping patients to change their lifestyles. This study compared the efficacy of two different educational models on reducing blood pressure (BP). METHODS:This was a randomized controlled trial in ambulatory hypertensive patients >65 years of a...

journal_title：American journal of hypertension

authors： Figar S,Galarza C,Petrlik E,Hornstein L,Rodríguez Loria G,Waisman G,Rada M,Soriano ER,de Quirós FG

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Complement factor H (CFH) is a plasma protein that is essential in the regulation of the alternative complement pathway and has been implicated as taking part in complement inhibition in atherogenesis. We evaluated the association of the Y402H polymorphism with incident coronary heart disease (CHD), incident...

journal_title：American journal of hypertension

authors： Volcik KA,Ballantyne CM,Braun MC,Coresh J,Mosley TH,Boerwinkle E

更新日期：2008-05-01 00:00:00

abstract：:To assess whether aerobic exercise training is an effective and an alternative method to control blood pressure (BP) in hypertension, 32 uncomplicated, never treated patients suffering from mild-to-moderate essential arterial hypertension (EAH) were included in an aerobic exercise training program using a regular stan...

journal_title：American journal of hypertension

authors： Nami R,Mondillo S,Agricola E,Lenti S,Ferro G,Nami N,Tarantino M,Glauco G,Spanò E,Gennari C

更新日期：2000-06-01 00:00:00

abstract：:Plasma plasminogen activator inhibitor type 1 (PAI-1) and tissue plasminogen activator (tPA) antigens and activities were measured in 28 patients with hypertension and 12 normal controls. Steady state plasma glucose (SSPG) concentrations were also determined after an infusion of somatostatin, insulin and glucose. Pati...

journal_title：American journal of hypertension

authors： Jeng JR,Sheu WH,Jeng CY,Huang SH,Shieh SM

更新日期：1996-05-01 00:00:00

abstract：:Smooth muscle cells from spontaneously hypertensive rats (SHR) proliferate in culture faster than those isolated from sex- and age-matched Wistar-Kyoto (WKY) animals. There was no difference in the kinetics of S6 kinase activation in the two cultures, but later metabolic events associated with proliferation were stimu...

journal_title：American journal of hypertension

authors： Scott-Burden T,Resink TJ,Hahn AW,Bühler FR

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:It is known that essential hypertension may be implicated in the development of cognitive impairment that is associated to microvascular disease of the brain. It has been hypothesized that increased arterial stiffness of the large arteries may lead to microvascular changes due to increased pulsatile flow. Ou...

journal_title：American journal of hypertension

authors： Triantafyllidi H,Arvaniti C,Lekakis J,Ikonomidis I,Siafakas N,Tzortzis S,Trivilou P,Zerva L,Stamboulis E,Kremastinos DT

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Vitamin D is involved in blood pressure (BP) regulation. Genetic variations may influence the effect of vitamin D on BP, but data from epidemiologic studies remain inconsistent. METHODS:We conducted a comprehensive genetic association study in the Women's Genome Health Study (WGHS) with genome-wide genotype...

journal_title：American journal of hypertension

authors： Wang L,Chu A,Buring JE,Ridker PM,Chasman DI,Sesso HD

更新日期：2014-11-01 00:00:00

abstract：:High dietary Na+ raises mean arterial pressure (MAP) by more than 10% in salt-sensitive (SS) patients with essential hypertension. To test whether the rise in MAP in these patients is caused by a Na(+)-linked increase in [Ca2+]i in vascular smooth muscle cells, we measured [Ca2+]i in the lymphocytes of 14 patients wit...

journal_title：American journal of hypertension

authors： Alexiewicz JM,Gaciong Z,Parise M,Karubian F,Massry SG,Campese VM

更新日期：1992-08-01 00:00:00

abstract：:Mesangial cells in the glomerulus have several important physiological functions, as has been demonstrated by past research. Platelet derived growth factor, thrombin, endothelin, and angiotensin II have all been shown to affect mesangial cell growth and protein synthesis. First generation Ca channel blockers also have...

journal_title：American journal of hypertension

authors： Shultz PJ,Raij L

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Evaluating effect of acute or chronic use of antihypertensives on risk of falls in older adults. METHODS:Data sources: Systematic search of primary research articles in CINAHL, Cochrane, EBM, EMBASE, and MEDLINE databases from January 1 2007 to June 1 2017. Study selection: Research studies of cohort, case-...

journal_title：American journal of hypertension

authors： Kahlaee HR,Latt MD,Schneider CR

更新日期：2018-03-10 00:00:00

abstract：BACKGROUND:Subjects with renovascular hypertension (RVH) often manifest with metabolic syndrome (MetS) as well. Coexisting MetS and hypertension increases cardiovascular morbidity and mortality, but the mechanisms underlying cardiac injury remain unknown. We hypothesized that superimposition of MetS induces myocardial ...

journal_title：American journal of hypertension

authors： Aghajani Nargesi A,Farah MC,Zhu XY,Zhang L,Tang H,Jordan KL,Saadiq IM,Lerman A,Lerman LO,Eirin A

更新日期：2020-12-05 00:00:00

abstract：BACKGROUND:Elevated blood pressure (BP) is a risk factor for cardiovascular disease (CVD), but it remains unclear which component-alone or in combination-is the best predictor. We sought to determine which BP parameters are important predictors of CVD death across a wide age range. METHODS:We used a prospective cohort...

journal_title：American journal of hypertension

authors： Bowman TS,Sesso HD,Gaziano JM

更新日期：2006-01-01 00:00:00

abstract：:Plasma glucose and insulin responses to an oral glucose challenge and insulin-stimulated glucose uptake were measured in 47 age-, weight-, and sex-matched lean white men (16 with normal blood pressure, 14 with untreated hypertension, nine treated with a thiazide diuretic only, and eight treated with combined diuretic ...

journal_title：American journal of hypertension

authors： Swislocki AL,Hoffman BB,Reaven GM

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:While obesity is a leading risk factor for preeclampsia, the mechanisms whereby obese women are more susceptible to pregnancy-induced hypertension are unclear. As high-fat diet (HFD) is an important contributor to the development of obesity, we tested the hypothesis that pregnant rats on HFD have hypertensio...

journal_title：American journal of hypertension

authors： Palei AC,Spradley FT,Granger JP

更新日期：2017-03-01 00:00:00

abstract：:Recent findings related to the renin-angiotensin system have provided a more elaborated understanding of the pathophysiology of hypertension and kidney diseases. These findings have led to unique concepts and issues regarding the intrarenal renin-angiotensin system. Angiotensinogen is the only known substrate for reni...

journal_title：American journal of hypertension

authors： Kobori H,Ozawa Y,Suzaki Y,Prieto-Carrasquero MC,Nishiyama A,Shoji T,Cohen EP,Navar LG

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Left ventricular (LV) hypertrophy and impaired diastolic function may occur early in systemic hypertension, but longitudinal studies are missing. METHODS:We performed an echocardiographic follow-up study in young initially normotensive male offspring of hypertensive (OHyp) (n = 25) and normotensive (ONorm) ...

journal_title：American journal of hypertension

authors： Aeschbacher BC,Hutter D,Fuhrer J,Weidmann P,Delacrétaz E,Allemann Y

更新日期：2001-02-01 00:00:00

abstract：:The current study tested the hypothesis that centrally administered relaxin elevates arterial pressure in conscious rats and that this hypertensive effect is mediated, at least in part, by central or peripheral vasopressin. Injection of human relaxin (0.068 or 0.34 microgram in 200 nL artificial cerebrospinal fluid) i...

journal_title：American journal of hypertension

authors： Yang RH,Bunting S,Wyss JM,Berecek KH,Zhang L,Jin H

更新日期：1995-04-01 00:00:00