Angiotensin-induced growth related metabolism is activated in cultured smooth muscle cells from spontaneously hypertensive rats and Wistar-Kyoto rats.

abstract：:This study examined the effects of alterations in salt-intake on blood pressure (BP) in rats chronically treated intravenously with or without the nitric oxide synthase (NOS) inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME) (8.6 mg/kg/day). The changes in mean arterial pressure (MAP), the renal cortical and medul...

journal_title：American journal of hypertension

authors： Nakanishi K,Hara N,Nagai Y

更新日期：2002-02-01 00:00:00

abstract：:Pneumonia is a major direct cause of death in the elderly. Although aspiration based on a reduced cough reflex is one of the causes of pneumonia in the elderly, there are few studies of angiotensin-I converting enzyme inhibitors (ACE inhibitors), which are antihypertensive drugs that induce cough, as a factor influenc...

journal_title：American journal of hypertension

authors： Okaishi K,Morimoto S,Fukuo K,Niinobu T,Hata S,Onishi T,Ogihara T

更新日期：1999-08-01 00:00:00

abstract：:Onset of diabetes increases plasma renin activity (PRA) and glomerular filtration rate (GFR), but blood pressure (BP) is normal. In this study, a 70% surgical reduction in kidney mass (RK) was used to decrease baseline GFR and to prevent hyperfiltration during diabetes, and angiotensin converting enzyme inhibitors (AC...

journal_title：American journal of hypertension

authors： Rojas M,Bell TD,Sturgis LC,Springfield V,Janardhanan R,Fleming C,Brands MW

更新日期：2006-12-01 00:00:00

abstract：:The nonpeptide angiotensin II (AII)-receptor antagonist losartan is a selective blocker of the pressor effects of AII. It is now being evaluated as an anti-hypertensive drug in multicenter clinical trials in the United States and other countries. Preliminary inpatient studies have shown that after 5 days of treatment,...

journal_title：American journal of hypertension

authors： Weber MA

更新日期：1992-12-01 00:00:00

abstract：:Echocardiography (ECHO) is useful to document changes in left ventricular mass (LVM) in groups of patients, but may be too variable for use in the individual patient. Magnetic resonance imaging (MRI) may be a more precise and reliable method to quantify the mass of the left ventricule. This study reports the accuracy,...

journal_title：American journal of hypertension

authors： Bottini PB,Carr AA,Prisant LM,Flickinger FW,Allison JD,Gottdiener JS

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Endothelial progenitor cells (EPCs) provide paracrine support to the vascular endothelium and may also replace damaged or senescent endothelial cells. Low numbers of endothelial progenitor colony-forming units (CFU-ECs) in culture are a predictive biomarker of vascular disease. We hypothesized that the numbe...

journal_title：American journal of hypertension

authors： Lin C,Rajakumar A,Plymire DA,Verma V,Markovic N,Hubel CA

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Blood pressure (BP) responses to dietary sodium and potassium intake vary among individuals. We examined the correlation between BP responses to dietary low-sodium, high-sodium, and potassium supplementation interventions in a feeding study. METHODS:A total of 1,906 Chinese aged > or = 16 years participated...

journal_title：American journal of hypertension

authors： Zhao Q,Gu D,Chen J,Bazzano LA,Rao DC,Hixson JE,Jaquish CE,Cao J,Chen J,Li J,Rice T,He J

更新日期：2009-12-01 00:00:00

abstract：:Patients with hypertension tend to be glucose intolerant, hyperinsulinemic, and dyslipedemic. Since all of these changes increase risk of coronary heart disease (CHD), it is important to know what effect antihypertensive treatment has on these variables. The current open-labelled, uncontrolled study was initiated in o...

journal_title：American journal of hypertension

authors： Shieh SM,Sheu WH,Shen DD,Fuh MM,Jeng CY,Jeng JR,Chen YD,Reaven GM

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:The prevalence of hypertension in the Middle East is not well defined. We examined the prevalence, awareness, treatment, and control of hypertension in Iran. METHODS:The Survey of Risk Factors of Noncommunicable Diseases was conducted in 2005 and contains a representative sample of the Iranian adult populat...

journal_title：American journal of hypertension

authors： Esteghamati A,Abbasi M,Alikhani S,Gouya MM,Delavari A,Shishehbor MH,Forouzanfar M,Hodjatzadeh A,Ramezani RD

更新日期：2008-06-01 00:00:00

abstract：:There are a variety of radiopharmaceuticals that can be used to perform captopril renography effectively. We examined a number of technetium and iodine compounds and the circumstances under which each radiopharmaceutical compound is the compound of choice. Considerations of cost, ease of use, reliability, dosage, and ...

journal_title：American journal of hypertension

authors： Blaufox MD,Dubovsky EV,Hilson AJ,Taylor A Jr,de Zeeuw R

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:We reported that insulin modestly stimulates NAD(P)H oxidase activity in cultured rat vascular smooth muscle cells (VSMC) and synergistically stimulates enzyme activity with angiotensin II (Ang II), leading to synergistic stimulation of VSMC migration. The aim of this study was to determine the mechanism of ...

journal_title：American journal of hypertension

authors： Yang M,Kahn AM

更新日期：2006-06-01 00:00:00

abstract：:Hyperinsulinemia and dyslipidemia are known to be associated with essential hypertension but their role in pregnancy-induced hypertension remains unclear. We performed a case-control study comparing cholesterol, insulin, and glucose levels in the early third trimester of pregnancy among 31 women who developed pregnanc...

journal_title：American journal of hypertension

authors： Solomon CG,Carroll JS,Okamura K,Graves SW,Seely EW

更新日期：1999-03-01 00:00:00

abstract：:There is controversy over whether endothelial function is impaired in human essential hypertension. All studies to date have used measurements of forearm blood flow by plethysmography to assess endothelium-dependent vasodilation and endothelial function. In contrast to these studies, which have focused on resistance v...

journal_title：American journal of hypertension

authors： Schmieder RE,Weihprecht H,Schobel H,John S,Weidinger G,Gatzka C,Veelken R

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme inhibitors are the drugs of choice in renal hypertension. The efficacy and safety of ramipril in adults has been proved; however, data on effectiveness of ramipril in children are few. The aim of the present study was to investigate the effect of ramipril on blood pressure (BP) ...

journal_title：American journal of hypertension

authors： Seeman T,Dusek J,Vondrák K,Flögelová H,Geier P,Janda J

更新日期：2004-05-01 00:00:00

abstract：:Our objective was to evaluate pretreatment predictors of longevity, particularly blood pressure, in a large cohort of hypertensive men. During 1974 to 1976, 10,367 male hypertensive veterans (47% black) were identified at screening and subsequently characterized in 32 special Veterans Administration (VA) hypertension ...

journal_title：American journal of hypertension

authors： Perry HM Jr,Miller JP,Baty JD,Carmody SE,Sambhi MP

更新日期：2000-06-01 00:00:00

abstract：:Thromboembolic complications such as ischemic stroke and myocardial infarction are significantly more frequent in patients with arterial hypertension. From the available intervention studies, it appears that pharmacologic treatment of hypertension-at least with diuretics and beta-blockers-may more effectively protect ...

journal_title：American journal of hypertension

authors： Lottermoser K,Weisser B,Hertfelder HJ,Wöstmann B,Vetter H,Düsing R

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:On the basis of evidence of plasma leptin (LE) effects on cardiovascular system, we assessed possible association of LE and Doppler-derived left ventricular (LV) diastolic function in arterial hypertension. METHODS:Doppler echocardiography, blood sample for fasting plasma LE levels, and euglycemic hyperinsu...

journal_title：American journal of hypertension

authors： Galderisi M,Tagliamonte MR,D'Errico A,Carella C,Varricchio G,Mondillo S,de Divitiis O,Paolisso G

更新日期：2001-10-01 00:00:00

abstract：:Hypertension is a major risk factor for cardiovascular disease, and small reductions in blood pressure can have a substantial impact on outcome. Effective control of hypertension per se is important in reducing morbidity and mortality, but there is growing evidence that the class of drug used in treatment may affect p...

journal_title：American journal of hypertension

authors： Oparil S

更新日期：2002-01-01 00:00:00

abstract：:To assess whether aerobic exercise training is an effective and an alternative method to control blood pressure (BP) in hypertension, 32 uncomplicated, never treated patients suffering from mild-to-moderate essential arterial hypertension (EAH) were included in an aerobic exercise training program using a regular stan...

journal_title：American journal of hypertension

authors： Nami R,Mondillo S,Agricola E,Lenti S,Ferro G,Nami N,Tarantino M,Glauco G,Spanò E,Gennari C

更新日期：2000-06-01 00:00:00

abstract：:Endothelin-1 (ET-1) is a powerful vasoconstrictor peptide and regulator of blood flow that plays an important role in blood pressure (BP) elevation in some models of experimental hypertension such as DOCA-salt rat, DOCA-salt-treated spontaneously hypertensive rats (SHR), stroke-prone SHR, Dahl salt-sensitive rats, ang...

journal_title：American journal of hypertension

authors： Schiffrin EL

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:The reduction of coronary flow reserve (CFR) found in arterial hypertension may be due to changes in afterload, left ventricular (LV) structure, and metabolic factors. Also, insulin-like growth factor-1 (IGF-1) may be associated with the magnitude of CFR in relation to its modulating action on cardiac and en...

journal_title：American journal of hypertension

authors： Galderisi M,Caso P,Cicala S,De Simone L,Barbieri M,Vitale G,de Divitiis O,Paolisso G

更新日期：2002-09-01 00:00:00

abstract：:Renal artery stent placement has been shown to improve blood pressure (BP) and stabilize renal function in patients with atherosclerotic renovascular disease. However, limited data are available in patients > or = 75 years of age. We analyzed the prestent characteristics and clinical outcomes of patients aged > or = 7...

journal_title：American journal of hypertension

authors： Bloch MJ,Trost DA,Whitmer J,Pickering TG,Sos TA,August P

更新日期：2001-10-01 00:00:00

abstract：:To evaluate the existence of a relationship between atrial natriuretic factor (ANF) and plasma Na+/K+ATPase inhibitory activity in humans, we examined the hemodynamic and humoral response to volume expansion in 41 borderline hypertensive patients (BHT) with either normal (n = 33) or low plasma renin activity (n = 8). ...

journal_title：American journal of hypertension

authors： Borghi C,Boschi S,Costa FV,Ambrosioni E

更新日期：1991-07-01 00:00:00

abstract：:In essential hypertension (EHT) the presence of a metabolic syndrome increases the risk of cardiovascular disease. A cell membrane abnormality is implicated but its role in cardiovascular disease is unclear. Neutrophil accumulation, which occurs by beta2-integrin (CD11b/CD18) expression, followed by release of proinfl...

journal_title：American journal of hypertension

authors： Fardon NJ,Wilkinson R,Thomas TH

更新日期：2001-09-01 00:00:00

abstract：:In normal coronary arteries, increased flow velocity induces endothelium-dependent dilation, and dilation in response to sympathetic stimulation evoked by the cold pressor test is partly due to increased flow velocity. In arterial hypertension, angiographically normal coronary arteries were constricted by acetylcholin...

journal_title：American journal of hypertension

authors： Nitenberg A,Antony I,Aptecar E,Arnoult F,Lerebours G

更新日期：1995-05-01 00:00:00

abstract：:In a 10-year prospective study, we investigated the utility of the serum creatinine level in predicting the development of hypertension in Japanese adults, all of whom lived in a rural community. The study included 229 subjects, 91 men and 138 women aged 30 to 69 years, who were normotensive (systolic blood pressure 1...

journal_title：American journal of hypertension

authors： Miura K,Nakagawa H,Nakamura H,Tabata M,Nagase H,Yoshida M,Okada A

更新日期：1994-05-01 00:00:00

abstract：:Twenty-four hour blood pressure exposure and circadian blood pressure variability may be important predictors of hypertensive end-organ damage. Since sleep is a major determinant of circadian blood pressure decline, day/night blood pressure changes may be affected by sleep intervals. The current study compares 24-h bl...

journal_title：American journal of hypertension

authors： Rosansky SJ,Menachery SJ,Wagner CM,Jackson K

更新日期：1995-07-01 00:00:00

abstract：:The present study evaluated the effects of miconazole, a selective inhibitor of epoxygenase activity, on renal hemodynamics and the pressure-natriuresis response of saline-drinking, uninephrectomized Lyon hypertensive (LH) and Lyon low blood pressure (LL) rats. Infusion of miconazole (final concentration, 1 micromol/L...

journal_title：American journal of hypertension

authors： Messer-Létienne I,Bernard N,Roman RJ,Sassard J,Benzoni D

更新日期：1999-04-01 00:00:00

abstract：:High K diets prevent hypertensive endothelial injury and intimal thickening. Cholesterol esters often deposit during hypercholesterolemia. Would a high K diet influence cholesterol ester deposits? In a normal rat on a normal diet, no cholesterol esters are detected in the aorta. Stroke prone SHR rats were fed for 3 mo...

journal_title：American journal of hypertension

authors： Tobian L,Jahner TM,Johnson MA

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Inflammation is an independent risk factor for high blood pressure, and as a consequence inflammatory cytokines could be related with left ventricular hypertrophy (LVH). We sought to assess the association and predictive role of different cytokine levels with LVH in a group of patients with essential hyperte...

journal_title：American journal of hypertension

authors： Roselló-Lletí E,Rivera M,Martínez-Dolz L,González Juanatey JR,Cortés R,Jordán A,Morillas P,Lauwers C,Calabuig JR,Antorrena I,de Rivas B,Portolés M,Bertomeu V

更新日期：2009-04-01 00:00:00