Independent association of plasma leptin levels and left ventricular isovolumic relaxation in uncomplicated hypertension.

abstract：:It has been suggested that atheroma formation is a chronic inflammatory response to lipid-derived inflammatory mediators accumulating at selected arterial sites. At large artery flow dividers and curvatures, secondary flow phenomena create zones of stagnation and recirculation that deprive endothelial cells of shear s...

journal_title：American journal of hypertension

authors： Henry PD,Chen CH

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Elevated blood pressure (BP) is a risk factor for cardiovascular disease (CVD), but it remains unclear which component-alone or in combination-is the best predictor. We sought to determine which BP parameters are important predictors of CVD death across a wide age range. METHODS:We used a prospective cohort...

journal_title：American journal of hypertension

authors： Bowman TS,Sesso HD,Gaziano JM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Higher fibroblast growth factor-23 (FGF23) concentrations have been found to be associated with incident heart failure (HF). Experimental data suggest FGF23 directly stimulates myocardial hypertrophy. FGF23 may also enhance renin-angiotensin-aldosterone system activity. Whether FGF23 is associated with incre...

journal_title：American journal of hypertension

authors： Akhabue E,Vu TT,Vaidya A,Michos ED,de Boer IH,Kestenbaum B,Allison M,Szklo M,Ouyang P,Yancy CW,Wolf M,Isakova T,Carnethon MR

更新日期：2019-01-01 00:00:00

abstract：:Recent findings related to the renin-angiotensin system have provided a more elaborated understanding of the pathophysiology of hypertension and kidney diseases. These findings have led to unique concepts and issues regarding the intrarenal renin-angiotensin system. Angiotensinogen is the only known substrate for reni...

journal_title：American journal of hypertension

authors： Kobori H,Ozawa Y,Suzaki Y,Prieto-Carrasquero MC,Nishiyama A,Shoji T,Cohen EP,Navar LG

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Parathyroid hormone (PTH) stimulates aldosterone secretion in human adrenocortex and is regulated by the renin-angiotensin-aldosterone system. We speculated that measurement of PTH may be a valuable aid in the diagnosis of aldosterone-producing adenoma (APA). METHODS:To test this hypothesis, we recruited 14...

journal_title：American journal of hypertension

authors： Zhang LX,Gu WJ,Li YJ,Wang Y,Wang WB,Wang AP,Shen L,Zang L,Yang GQ,Lu ZH,Dou JT,Mu YM

更新日期：2016-05-01 00:00:00

abstract：:We sought to determine whether reductions in blood pressure in hypertensives after acute exercise persist for more than the 2 to 3 h found in controlled laboratory settings. Subjects (n = 11) were obese (32 +/- 4% body fat), sedentary (VO2max 27 +/- 4 mL/kg/min) 60 +/- 6-year-old men with stage 1 or 2 essential hypert...

journal_title：American journal of hypertension

authors： Taylor-Tolbert NS,Dengel DR,Brown MD,McCole SD,Pratley RE,Ferrell RE,Hagberg JM

更新日期：2000-01-01 00:00:00

abstract：:Cocaine causes acute hypertension by blocking catecholamine reuptake. There is evidence that it also impairs the peripheral endothelial nitric oxide system, which is normally vasodilatory. We further explored the role of nitric oxide in cocaine-induced vasoconstriction in anesthetized rats, and in vitro by using isola...

journal_title：American journal of hypertension

authors： Mo W,Singh AK,Arruda JA,Dunea G

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:The prevalence of hypertension in the Middle East is not well defined. We examined the prevalence, awareness, treatment, and control of hypertension in Iran. METHODS:The Survey of Risk Factors of Noncommunicable Diseases was conducted in 2005 and contains a representative sample of the Iranian adult populat...

journal_title：American journal of hypertension

authors： Esteghamati A,Abbasi M,Alikhani S,Gouya MM,Delavari A,Shishehbor MH,Forouzanfar M,Hodjatzadeh A,Ramezani RD

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Although the acute increase of arterial stiffness and blood pressure (BP) after cigarette smoking in healthy smokers is considered a possible mechanism of increased cardiovascular risk, the acute effect of smoking on arterial stiffness in hypertensive smokers is unknown. We investigated the acute effects of ...

journal_title：American journal of hypertension

authors： Rhee MY,Na SH,Kim YK,Lee MM,Kim HY

更新日期：2007-06-01 00:00:00

abstract：:The levels and molecular form of atrial natriuretic peptide-like immunoreactivity (ANP-LI) in human atrial tissue were investigated. The levels of right atrial ANP-LI were significantly higher in mitral disease than in other cardiac or noncardiac diseases. The increased ANP-LI was mainly accounted for by an increase i...

journal_title：American journal of hypertension

authors： Naruse M,Hiroe M,Naruse K,Nagata M,Ohno H,Hashimoto A,Koyanagi H,Sekiguchi M,Demura H,Hirosawa K

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Most healthy people exhibit a decrease in systolic blood pressure (SBP) at night. A drop of <10% from mean daytime values, "non-dipping," is associated with kidney disease and cardiovascular events. We hypothesized that non-dipping would predict all-cause mortality. METHODS:Consecutive patients referred for...

journal_title：American journal of hypertension

authors： Brotman DJ,Davidson MB,Boumitri M,Vidt DG

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Schlager inbred hypertensive mice (BPH/2J) have been suggested to have high blood pressure (BP) due to an overactive sympathetic nervous system (SNS). The brain nuclei associated with the hypertension are also those involved in the integration of the cardiovascular responses to stress. Therefore, in the pres...

journal_title：American journal of hypertension

authors： Davern PJ,Jackson KL,Nguyen-Huu TP,La Greca L,Head GA

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Liddle's syndrome (LS) is a monogenic form of hypertension simulating a mineralocorticoid excess, and is currently suspected in young hypokalemic hypertensives. The aims of the study were: (i) to evaluate the clinical phenotype of LS in a newly identified Italian family of Sicilian origin carrying a gain-of-...

journal_title：American journal of hypertension

authors： Rossi E,Farnetti E,Nicoli D,Sazzini M,Perazzoli F,Regolisti G,Grasselli C,Santi R,Negro A,Mazzeo V,Mantero F,Luiselli D,Casali B

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Sleep apnea is being studied as a risk factor for hypertension. This observational chart review was conducted to determine the long-term effects of continuous positive airway pressure (CPAP) treatment on blood pressure (BP) in a sample of sleep apnea patients from urban and rural populations. METHODS:This s...

journal_title：American journal of hypertension

authors： Dhillon S,Chung SA,Fargher T,Huterer N,Shapiro CM

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Carotid-femoral pulse-wave velocity (PWV) provides a comprehensive noninvasive indication of arterial stiffness, and is now established as a strong marker of cardiovascular disease (CVD). The correlation between peripheral blood pressure (BP) and PWV and their respective influences on mortality have been poo...

journal_title：American journal of hypertension

authors： Miljkovic D,Perret-Guillaume C,Alla F,Salvi P,Erpelding ML,Benetos A

更新日期：2013-02-01 00:00:00

abstract：:In order to examine the relationship existing between dietary calcium and the development of hypertension, we developed a long-term study in the Lyon hypertensive rat strain (LH) and two control strains, the Lyon normotensive (LN) and low blood pressure rats (LL) given enriched (HCa, 2.5%), deprived (LCa, 0.03%) and n...

journal_title：American journal of hypertension

authors： Pernot F,Schleiffer R,Bergmann C,Vincent M,Sassard J,Gairard A

更新日期：1990-11-01 00:00:00

abstract：:In recent years, several international bodies of experts have established extensive guidelines for the prevention and treatment of coronary heart disease (CHD) that clearly define the importance of altering patients' lifestyles and administering therapeutic agents that positively affect disease progression. However, s...

journal_title：American journal of hypertension

authors： Erhardt LR

更新日期：1999-10-01 00:00:00

abstract：:To clarify the function of polymorphonuclear leukocytes (PMN) in spontaneously hypertensive rats (SHR) and the effect of beraprost sodium (BS) on these functions, we examined superoxide anion (O2-) production and adherent activity by PMN, as well as modification of these functions by BS ex vivo and in vitro. In study ...

journal_title：American journal of hypertension

authors： Ohmori M,Kitoh Y,Kawaguchi A,Harada K,Sugimoto K,Fujimura A

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Normal pregnancy is characterized by a decrease in peripheral resistance and generalized vasodilation resulting in plasma volume expansion, which is associated with intrauterine growth. Stiffness of the arterial system may be a measure of the degree of plasma volume expansion. Pulse wave velocity (PWV), meas...

journal_title：American journal of hypertension

authors： Elvan-Taspinar A,Franx A,Bots ML,Koomans HA,Bruinse HW

更新日期：2005-03-01 00:00:00

abstract：:We have previously reported that young, primigravid, African-American women who developed preeclampsia exhibited insulin resistance (elevated fasting insulin:glucose ratios) and abnormal intracellular free calcium ([Ca2+]i) metabolism as early as the second trimester of pregnancy. To determine if these abnormalities p...

journal_title：American journal of hypertension

authors： Sowers JR,Standley PR,Jacober S,Niyogi T,Simpson L

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:The expression of Na(+)-K(+)-2Cl(-) cotransporter 1 (NKCC1) is upregulated in spontaneously hypertensive rat (SHR). We investigated whether expression of NKCC1 is epigenetically regulated during postnatal development of hypertension. METHODS:The mesenteric arteries from 5-, 10-, and 18-week-old Wistar-Kyoto...

journal_title：American journal of hypertension

authors： Cho HM,Lee HA,Kim HY,Han HS,Kim IK

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Nocturnal blood pressure (BP) is associated with risk for cardiovascular events. However, the relationship between nocturnal BP in young adults and cognitive function in midlife remains unclear. METHODS:We used data from the ambulatory BP monitoring substudy of the Coronary Artery Risk Development in Young ...

journal_title：American journal of hypertension

authors： Yano Y,Ning H,Muntner P,Reis JP,Calhoun DA,Viera AJ,Levine DA,Jacobs DR Jr,Shimbo D,Liu K,Greenland P,Lloyd-Jones D

更新日期：2015-10-01 00:00:00

abstract：:It is likely that a number of independent heritable traits, each encoded by a singular gene, contribute to pathologic elevations in blood pressure in humans. Genetic polymorphisms of individual genes may result in intermediate phenotypes which, by themselves, do not raise blood pressure, but, coupled with environmenta...

journal_title：American journal of hypertension

authors： Freeman K,Farrow S,Schmaier A,Freedman R,Schork T,Lockette W

更新日期：1995-09-01 00:00:00

abstract：:The purpose of this double-blind, forced titration study was to compare the antihypertensive effect duration of candesartan cilexetil, which has a longlasting binding to the human AT1-receptor, to that of losartan on ambulatory BP (ABP) not only during the 24-h dosing interval but also during the day of a missed dose ...

journal_title：American journal of hypertension

authors： Lacourcière Y,Asmar R

更新日期：1999-12-01 00:00:00

abstract：:Recently, we described a circulating hypertensive factor, present in the plasma of spontaneously hypertensive rats (SHR). This factor seems to be produced by the parathyroid gland but is not identical to parathyroid hormone (PTH). In view of these findings, we attempted to search for histological differences in parath...

journal_title：American journal of hypertension

authors： Kaneko T,Ohtani R,Lewanczuk RZ,Pang PK

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Marinobufagenin (MBG) is an endogenous Na/K-ATPase inhibitor, a natriuretic and a vasoconstrictor. MBG is implicated in salt-sensitive hypertension, cardiac hypertrophy, and initiate the pro-fibrotic signaling. Previously it was demonstrated that immunoneutralization of an endogenous MBG by 3E9 anti-MBG-anti...

journal_title：American journal of hypertension

authors： Grigorova YN,Juhasz O,Zernetkina V,Fishbein KW,Lakatta EG,Fedorova OV,Bagrov AY

更新日期：2016-05-01 00:00:00

abstract：:Vasoconstrictor and Na/K pump inhibitory properties of a bufodienolide Na/K-ATPase inhibitor, marinobufagenin, were studied in isolated rings of 2 to 3 order branches of human pulmonary arteries respectively. Marinobufagenin displayed concentration-dependent vasoconstrictor activity (0.01 to 10 mmol/L). In sarcolemma ...

journal_title：American journal of hypertension

authors： Bagrov AY,Dmitrieva RI,Fedorova OV,Kazakov GP,Roukoyatkina NI,Shpen VM

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Clonidine, a centrally acting antihypertensive agent, has been used successfully in pregnancy. We sought to describe the pharmacodynamic effects of clonidine in pregnancy and the associated impact on fetal growth. METHODS:A retrospective cohort study was performed. Maternal hemodynamics were measured before...

journal_title：American journal of hypertension

authors： Rothberger S,Carr D,Brateng D,Hebert M,Easterling TR

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Blood pressure is known to be higher in heavy drinkers than in nondrinkers. The aim of this study was to determine whether the alcohol-blood pressure relationship is modified by therapy for hypertension in the elderly. METHODS:Men aged > or = 65 years (n = 1,396) with or without current history of antihyper...

journal_title：American journal of hypertension

authors： Wakabayashi I

更新日期：2010-06-01 00:00:00

abstract：:Arterial hypertension is the most common chronic medical condition requiring office visits to physicians and is a major contributing factor to the development of myocardial infarction and stroke. Its importance as a cardiovascular risk factor is at least as significant in women as in men; however, the ever-growing lit...

journal_title：American journal of hypertension

authors： Ruilope LM,Suarez C

更新日期：1997-10-01 00:00:00