Dietary calcium, vascular reactivity, and genetic hypertension in the Lyon rat strain.

abstract：:Stroke-prone spontaneously hypertensive rats (SHRSP), subjected to high NaCl, show severe hypertension, organ damage, and early death. Preventive treatment with angiotensin II type 1 (AT1) receptor antagonists is known to be effective. Previously, we found that angiotensin converting enzyme (ACE) inhibition could redu...

journal_title：American journal of hypertension

authors： Blezer EL,Nicolay K,Koomans HA,Joles JA

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:To determine all-cause and circulatory system (cardiovascular)-related mortality in subjects with different grades of hypertension, we performed a prospective study. METHODS:A total of 148,173 individuals aged > or =35 years were recruited in Mumbai, India in years 1991-1997. Clinical history and anthropome...

journal_title：American journal of hypertension

authors： Pednekar MS,Gupta R,Gupta PC

更新日期：2009-10-01 00:00:00

abstract：:We have previously reported that young, primigravid, African-American women who developed preeclampsia exhibited insulin resistance (elevated fasting insulin:glucose ratios) and abnormal intracellular free calcium ([Ca2+]i) metabolism as early as the second trimester of pregnancy. To determine if these abnormalities p...

journal_title：American journal of hypertension

authors： Sowers JR,Standley PR,Jacober S,Niyogi T,Simpson L

更新日期：1993-04-01 00:00:00

abstract：:An intravenous glucose tolerance test (IVGTT) was performed on 16 spontaneously hypertensive rats (SHR) and 15 Wistar-Kyoto rats (WKY) by challenging them with an intravenous glucose load of 0.125 g/100 g body weight. Serum glucose and insulin were measured at 0, 15, 30, 60, 120, and 240 min. In a second experiment, o...

journal_title：American journal of hypertension

authors： Gaboury CL,Karanja N,Holcomb SR,Torok J,McCarron DA

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Overweight/obese young men have increased sympatho-excitation to cold and pain stress-induced by the cold pressor test (CPT) that may lead to abnormal hemodynamic responses. Concurrent CPT and exercise may augment the sympathetic-induced increases in aortic blood pressure (BP), pressure wave reflection (augm...

journal_title：American journal of hypertension

authors： Kalfon R,Campbell J,Alvarez-Alvarado S,Figueroa A

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme (ACE) inhibitors and calcium channel blockers (CCBs) increase arterial compliance and decrease left ventricular mass in hypertensive patients. This study examined whether combined therapy has greater arterial and cardiac effects than doubled doses of the individual drugs. METHO...

journal_title：American journal of hypertension

authors： Neutel JM,Smith DH,Weber MA

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) is a member of the nuclear receptor family that has been implicated in cell differentiation and proliferation, glucose metabolism, macrophage development, and inflammatory responses. PPAR-gamma can be activated by a range of synthetic substances a...

journal_title：American journal of hypertension

authors： Limor R,Sharon O,Knoll E,Many A,Weisinger G,Stern N

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Components of the renin-angiotensin-aldosterone system (RAAS) and a prothrombotic state are predictors of cardiovascular events in hypertensive patients. A relationship between the RAAS and the coagulation/fibrinolytic systems has been demonstrated, but its clinical relevance in hypertension is unclear. We i...

journal_title：American journal of hypertension

authors： Sechi LA,Novello M,Colussi G,Di Fabio A,Chiuch A,Nadalini E,Casanova-Borca A,Uzzau A,Catena C

更新日期：2008-12-01 00:00:00

abstract：:The purpose of this study was to examine the variability of 24-hour urinary and serum creatinine levels and creatinine clearance in normal subjects and to develop nomograms for assessing the adequacy of 24-hour urine collections. The data were from a longitudinal research program examining biochemical, hormonal, and h...

journal_title：American journal of hypertension

authors： James GD,Sealey JE,Alderman M,Ljungman S,Mueller FB,Pecker MS,Laragh JH

更新日期：1988-04-01 00:00:00

abstract：:Despite intense investigation and clinical attention, many challenges remain in the management of the hypertensive patient. It is clear that hypertension remains inadequately controlled worldwide, with the control rate in the United States approximating 27%. Furthermore, several recent studies have underscored that it...

journal_title：American journal of hypertension

authors： Epstein M

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Although cardiovascular (CV) risks are reported in first-degree relatives (FDRs) of type 2 diabetics, effects of gender on sympathovagal imbalance (SVI) and CV risks in these subjects have not been investigated. METHODS:Body mass index (BMI), blood pressure variability parameters including baroreflex sensit...

journal_title：American journal of hypertension

authors： Pal GK,Adithan C,Ananthanarayanan PH,Pal P,Nanda N,Durgadevi T,Lalitha V,Syamsunder AN,Dutta TK

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus (DM) and hypertension (HT) frequently coexist. Increased central aortic pressures indexes are associated with HT; however, possible associations of these indexes with future development of DM have never been studied in HT. METHODS:We recruited 178 patients with uncomplicated nondiabetic HT...

journal_title：American journal of hypertension

authors： Chen JY,Chou CH,Lee YL,Tsai WC,Lin CC,Huang YY,Chen JH

更新日期：2010-10-01 00:00:00

abstract：:Hypertension is a major risk factor for cardiovascular disease, and small reductions in blood pressure can have a substantial impact on outcome. Effective control of hypertension per se is important in reducing morbidity and mortality, but there is growing evidence that the class of drug used in treatment may affect p...

journal_title：American journal of hypertension

authors： Oparil S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Left ventricular (LV) concentric geometry and hypertrophy, depressed wall mechanics, and abnormal diastolic properties have been described in the diabetic heart. However, the cardiac response to dynamic exercise in diabetic patients remains controversial. The present study assessed strain rate (SR) imaging d...

journal_title：American journal of hypertension

authors： Galderisi M,de Simone G,Innelli P,Turco A,Turco S,Capaldo B,Riccardi G,de Divitiis O

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Reduced synthesis of nitric oxide (NO) is considered a major proatherogenic mechanism in patients with end-stage renal disease (ESRD), but genetic factors impinging on this mechanism have been little studied in this population. METHODS:We tested the relationship between carotid intima-media thickness (IMT) ...

journal_title：American journal of hypertension

authors： Spoto B,Benedetto FA,Testa A,Tripepi G,Mallamaci F,Maas R,Boeger RH,Zoccali C

更新日期：2007-07-01 00:00:00

abstract：:Using a new ion selective electrode (ISE) to measure ionized magnesium (IMg2+), we compared levels of IMg2+ with total magnesium (TMg) and serum ionized calcium levels (ICa2+) in umbilical arterial and venous serum of 13 parturients who developed transient hypertension in labor with levels in 38 who remained normotens...

journal_title：American journal of hypertension

authors： Handwerker SM,Altura BT,Royo B,Altura BM

更新日期：1993-06-01 00:00:00

abstract：:Concentrations of sodium-transport inhibitors (STI) which block the sodium-potassium-ATPase pump are increased in the plasma and urine of volume-expanded and low-renin hypertensive humans and animals. To evaluate the physiologic relevance of STI to blood-pressure-raising mechanisms, we have examined the in vitro prope...

journal_title：American journal of hypertension

authors： Weber MA,Weiler E,Gonick HC,Prins BA,Purdy RE

更新日期：1989-10-01 00:00:00

abstract：:The comparative efficacy of the calcium antagonists isradipine and nifedipine in reducing left ventricular peak systolic wall tension was assessed in 25 patients with essential hypertension (20 men, 5 women; mean age: 49 years). After 2 weeks of treatment with either isradipine (2.5 mg twice daily) or slow-release nif...

journal_title：American journal of hypertension

authors： Griebenow R,Müller R,Steffen HM,Burger KJ,Welzel D

更新日期：1993-03-01 00:00:00

abstract：:Arterial hypertension is a powerful risk factor for cardiovascular disease, but the ability to use blood pressure measurements to predict complications in individual patients or small groups is limited. One possible approach to identifying hypertensive patients at high risk is based on the observation that the presenc...

journal_title：American journal of hypertension

authors： Devereux RB

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Hypertension and smoking independently contribute to the risk of stroke. Our objective was to investigate home blood pressure (HBP) levels, day-by-day BP variability, and smoking in the prediction of stroke in Japanese men. METHODS:In this study, 902 men (mean age, 58.6 years) without a past history of stro...

journal_title：American journal of hypertension

authors： Hashimoto T,Kikuya M,Ohkubo T,Satoh M,Metoki H,Inoue R,Asayama K,Kanno A,Obara T,Hirose T,Hara A,Hoshi H,Totsune K,Satoh H,Sato H,Imai Y

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Obesity is a risk factor for the development of cardiovascular diseases that are associated with impaired angiogenesis. Nifedipine, a calcium-channel blocker, has a number of blood pressure (BP)-independent effects as well, such as improving endothelial function and decreasing oxidative stress. Here, we inve...

journal_title：American journal of hypertension

authors： Kito T,Shibata R,Kondo M,Yamamoto T,Suzuki H,Ishii M,Murohara T

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Hypertension (HTN) is a known major cardiovascular disease risk factor, but prevalence, treatment, and control of HTN among rapidly growing minority groups such as Asian Americans and Hispanics are unknown largely due to either underrepresentation in epidemiologic studies or aggregation of Asian American sub...

journal_title：American journal of hypertension

authors： Zhao B,Jose PO,Pu J,Chung S,Ancheta IB,Fortmann SP,Palaniappan LP

更新日期：2015-05-01 00:00:00

abstract：:This study was undertaken to examine whether prostaglandin (PG) inhibition with indomethacin interferes with angiotensin II receptor blockade (losartan) during treatment for arterial hypertension. In a double-blind crossover design 10 patients with essential arterial hypertension and treated with losartan were randomi...

journal_title：American journal of hypertension

authors： Olsen ME,Thomsen T,Hassager C,Ibsen H,Dige-Petersen H

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Noninvasive applanation tonometry (APT) is useful to assess aortic stiffness and pulse wave reflection. Moreover, APT can predict outcome in many conditions such as arterial hypertension. In this study, we test whether APT measurements relate to progression of aortic disease in Marfan syndrome (MFS). METHOD...

journal_title：American journal of hypertension

authors： Mortensen K,Aydin MA,Rybczynski M,Baulmann J,Schahidi NA,Kean G,Kühne K,Bernhardt AM,Franzen O,Mir T,Habermann C,Koschyk D,Ventura R,Willems S,Robinson PN,Berger J,Reichenspurner H,Meinertz T,von Kodolitsch Y

更新日期：2009-09-01 00:00:00

abstract：:A wide pulse pressure (PP) may constitute an independent predictor of cardiovascular morbidity and mortality. We assessed the reference values of brachial clinic PP, according to age and gender in a nonselected population (61,724 subjects) who were undergoing a routine systematic health examination. According to mean ...

journal_title：American journal of hypertension

authors： Asmar R,Vol S,Brisac AM,Tichet J,Topouchian J

更新日期：2001-05-01 00:00:00

abstract：:Renal artery stent placement has been shown to improve blood pressure (BP) and stabilize renal function in patients with atherosclerotic renovascular disease. However, limited data are available in patients > or = 75 years of age. We analyzed the prestent characteristics and clinical outcomes of patients aged > or = 7...

journal_title：American journal of hypertension

authors： Bloch MJ,Trost DA,Whitmer J,Pickering TG,Sos TA,August P

更新日期：2001-10-01 00:00:00

abstract：:Kidney stones affect hypertensive patients disproportionately compared to normotensive individuals. On the other hand, some prospective data suggest that a history of nephrolithiasis was associated with a greater tendency to develop hypertension. Newer epidemiologic data also link obesity and diabetes, features of the...

journal_title：American journal of hypertension

authors： Obligado SH,Goldfarb DS

更新日期：2008-03-01 00:00:00

abstract：:Decreased urinary kallikrein excretion has been shown to be related to hypertension. Kallikrein levels also have been shown to be determined primarily by genes, with 51% of the total variance being due to a single gene. However, there exists strong spouse-spouse correlation, indicating that common environment plays a ...

journal_title：American journal of hypertension

authors： Hunt SC,Wu LL,Slattery ML,Meikle AW,Williams RR

更新日期：1993-03-01 00:00:00

abstract：:Both nitric oxide (NO) and endothelin-1 (ET-1) are important mediators in the regulation of vascular tone during pregnancy and preeclampsia. This study was designed to investigate the ET-1-induced hypotensive effect in late pregnant rats (P) and in NO-deprived hypertensive pregnant rats (TP), a model of preeclampsia. ...

journal_title：American journal of hypertension

authors： Matz RL,Van Overloop B,Gairard A

更新日期：2001-06-01 00:00:00

abstract：:Blood pressure normally follows a characteristic pattern throughout the 24 h cycle with daytime pressures higher than nighttime pressures. Patients lacking a nocturnal decrease in pressure have a higher incidence of end organ damage. This investigation was designed to characterize the diurnal pattern of blood pressure...

journal_title：American journal of hypertension

authors： Marx MA,Gardner SF,Ketel BL

更新日期：1996-08-01 00:00:00