Rapid fusion of granules with neutrophil cell membranes in hypertensive patients may increase vascular damage.

abstract：:It has been speculated for some time that various antihypertensive medications may have a deleterious effect on respiration during sleep and thereby enhance the apparent association between hypertension and sleep apnea/hypopnea (SAH). However, there are few data to support this contention. The present study used a dou...

journal_title：American journal of hypertension

authors： Bartel PR,Loock M,Becker P,Robinson E,van der Meyden C,Rossouw S

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:The angiotensin II type 1 receptor A1166C polymorphism has been associated with increased risks of hypertension and myocardial infarction in several small studies. We examined the association between this polymorphism and new-onset hypertension, blood pressure (BP) control, and incident cardiovascular events...

journal_title：American journal of hypertension

authors： Hindorff LA,Heckbert SR,Tracy R,Tang Z,Psaty BM,Edwards KL,Siscovick DS,Kronmal RA,Nazar-Stewart V

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Masked hypertension (MHT), defined as normal blood pressure (BP) at office associated with high BP at home, has been shown to be associated with an increased risk of vascular events. However, MHT is poorly known in the elderly, although this age segment is at high risk of hypertension-related vascular events...

journal_title：American journal of hypertension

authors： Cacciolati C,Hanon O,Alpérovitch A,Dufouil C,Tzourio C

更新日期：2011-06-01 00:00:00

abstract：:The results of ambulatory blood pressure monitoring (ABPM) in children after kidney transplant were analyzed to ascertain any alteration in circadian BP profile, degree of hypertension, and efficacy of therapy. The data were also compared with casual BP data and left ventricular mass index (LVMI). We have examined 30 ...

journal_title：American journal of hypertension

authors： Calzolari A,Giordano U,Matteucci MC,Pastore E,Turchetta A,Rizzoni G,Alpert B

更新日期：1998-04-01 00:00:00

abstract：:It is likely that a number of independent heritable traits, each encoded by a singular gene, contribute to pathologic elevations in blood pressure in humans. Genetic polymorphisms of individual genes may result in intermediate phenotypes which, by themselves, do not raise blood pressure, but, coupled with environmenta...

journal_title：American journal of hypertension

authors： Freeman K,Farrow S,Schmaier A,Freedman R,Schork T,Lockette W

更新日期：1995-09-01 00:00:00

abstract：:The aim of this study was to assess the contribution of physical activity levels to blood pressure (BP) variability, and to assess the effect age, gender, body mass index, and use of antihypertensive medications on this relationship. We simultaneously monitored 24-h ambulatory BP by automated recorder and activity by ...

journal_title：American journal of hypertension

authors： Leary AC,Donnan PT,MacDonald TM,Murphy MB

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:In hypertensives, nondippers are more likely than dippers to suffer silent, as well as overt, hypertensive target organ damage. In this study, we investigated whether a nondipper status was associated with target organ damage in normotensives. METHODS:We performed ambulatory blood pressure (BP) monitoring, ...

journal_title：American journal of hypertension

authors： Hoshide S,Kario K,Hoshide Y,Umeda Y,Hashimoto T,Kunii O,Ojima T,Shimada K

更新日期：2003-06-01 00:00:00

abstract：:In this study we have compared Ca2+ efflux in cultured aortic smooth muscle cells derived from male, 10-week-old spontaneously hypertensive and Wistar-Kyoto rats. The role of Ca(2+)-dependent protein kinase C and Ca2+ uptake in the regulation of the Ca2+ pump and Na(+)-Ca2+ exchange mediated Ca2+ efflux were investiga...

journal_title：American journal of hypertension

authors： Chen S,Monteith GR,Roufogalis BD

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:B-type natriuretic peptide (BNP) increases the risk of death and cardiovascular events in patients without heart failure, even at BNP values within the "normal" range. The reasons for this are unclear. METHODS:We performed two separate studies (n = 33 and n = 129) on subjects with type 2 diabetes mellitus i...

journal_title：American journal of hypertension

authors： Dawson A,Davies JI,Morris AD,Struthers AD

更新日期：2005-12-01 00:00:00

abstract：:Decreased urinary kallikrein excretion has been shown to be related to hypertension. Kallikrein levels also have been shown to be determined primarily by genes, with 51% of the total variance being due to a single gene. However, there exists strong spouse-spouse correlation, indicating that common environment plays a ...

journal_title：American journal of hypertension

authors： Hunt SC,Wu LL,Slattery ML,Meikle AW,Williams RR

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:High waist circumference (WC) (women: >88 cm; men: >102 cm) increases cardiovascular risk. Less is known about moderate WC (women: 80-88 cm; men: 94-102 cm). Therefore, we examined the association between moderate WC and hypertension prevalence, independent of body mass index (BMI). METHODS:Among 24,247 eli...

journal_title：American journal of hypertension

authors： Levine DA,Calhoun DA,Prineas RJ,Cushman M,Howard VJ,Howard G

更新日期：2011-04-01 00:00:00

abstract：:The peak incidence of cardiovascular complications in the morning points to a possible role of the abrupt increase in blood pressure on arising. However, there is as yet no firm evidence linking the extent of the elevation in blood pressure on arising and the risk of cardiovascular complications. We sought a correlati...

journal_title：American journal of hypertension

authors： Gosse P,Ansoborlo P,Lemetayer P,Clementy J

更新日期：1997-05-01 00:00:00

abstract：:Insulin acutely inhibits contraction of primary cultured vascular smooth muscle (VSM) cells from canine femoral artery by inhibiting contractile agonist-induced Ca2+ influx. Insulin also inhibits contraction at step(s) distal to intracellular Ca2+ concentration (Ca2+i) by stimulating cyclic guanosine monophosphate (GM...

journal_title：American journal of hypertension

authors： Kahn AM,Allen JC,Seidel CL,Song T

更新日期：2000-04-01 00:00:00

abstract：:Cigarette smoking, an established cardiovascular (CV) disease risk factor, is known to impair pulsatile arterial function. However, information is scant in this regard on asymptomatic younger adult former smokers. As part of the Bogalusa Heart Study, the pulsatile arterial function was examined noninvasively in 278 no...

journal_title：American journal of hypertension

authors： Li H,Srinivasan SR,Berenson GS

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:The association of adiposity during childhood with future risk of elevated blood pressure (BP) in South Asian children is not known. We aimed to investigate the relationship between waist circumference (WC) and body mass index (BMI) with BP over a 2-year period, independent of the baseline BP. METHODS:We an...

journal_title：American journal of hypertension

authors： Almas A,Jafar TH

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Preeclampsia is a human pregnancy-associated syndrome associated with hypertension, proteinuria, and endothelial dysfunction. We tested whether increased reactive oxygen species (superoxide and peroxynitrite) production and decreased bioavailability of the endothelial nitric oxide (NO) synthase (eNOS) cofact...

journal_title：American journal of hypertension

authors： Mitchell BM,Cook LG,Danchuk S,Puschett JB

更新日期：2007-12-01 00:00:00

abstract：:To examine the influence of angiotensin-converting enzyme (ACE) on pressor, renal vascular, and adrenal responses during angiotensin I (Ang I) infusion, we studied 10 normotensive, healthy men. Each was in balance with a 10-mEq sodium, 100-mEq potassium intake and was studied before and during ACE inhibition with enal...

journal_title：American journal of hypertension

authors： Hollenberg NK,Fisher ND,Price DA,Williams GH

更新日期：2000-05-01 00:00:00

abstract：:This study was undertaken to examine whether prostaglandin (PG) inhibition with indomethacin interferes with angiotensin II receptor blockade (losartan) during treatment for arterial hypertension. In a double-blind crossover design 10 patients with essential arterial hypertension and treated with losartan were randomi...

journal_title：American journal of hypertension

authors： Olsen ME,Thomsen T,Hassager C,Ibsen H,Dige-Petersen H

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to test the hypothesis that angiotensin converting enzyme inhibition or angiotensin II antagonism can counteract cardiac human vascular endothelial growth factor-A165 (phVEGF-A165) induced angiogenesis. METHODS:Mice were given a single intramyocardial injection of phVEGF-A165. Eith...

journal_title：American journal of hypertension

authors： Siddiqui AJ,Mansson-Broberg A,Gustafsson T,Grinnemo KH,Dellgren G,Hao X,Fischer H,Sylvén C

更新日期：2005-10-01 00:00:00

abstract：:To determine whether baroreflex is changed centrally before the development of hypertension in DOCA-salt treated rats, aortic depressor nerve was stimulated electrically 5 days after DOCA-salt treatment in urethane-anesthetized rats: compared with those of sham-operated control rats, blood pressure was not elevated in...

journal_title：American journal of hypertension

authors： Takeda K,Nakamura Y,Oguro M,Kawasaki S,Hayashi J,Tanabe S,Nakata T,Lee LC,Sasaki S,Nakagawa M

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Obesity is one of the main determinants of blood pressure. The aim of this study was to evaluate and quantify the relations between the different anthropometric indices and blood pressure (BP) stratified by gender. METHODS:Cross-sectional analyses were performed using data from 2,105 adults from the ESTEBAN...

journal_title：American journal of hypertension

authors： Vallée A,Perrine AL,Deschamps V,Blacher J,Olié V

更新日期：2019-09-24 00:00:00

abstract：:In normal coronary arteries, increased flow velocity induces endothelium-dependent dilation, and dilation in response to sympathetic stimulation evoked by the cold pressor test is partly due to increased flow velocity. In arterial hypertension, angiographically normal coronary arteries were constricted by acetylcholin...

journal_title：American journal of hypertension

authors： Nitenberg A,Antony I,Aptecar E,Arnoult F,Lerebours G

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Blood pressure is a complex quantitative trait with a strong genetic component. In this study, we leveraged the Veterans Affairs electronic medical record system to explore the relationship between Paraoxonase 1 (PON1)-108 C/T (rs705379) and mean arterial blood pressure (MAP). METHODS:Outpatient blood press...

journal_title：American journal of hypertension

authors： Bhatnagar V,Liu L,Nievergelt CM,Richard E,Brophy VH,Pandey B,Lipkowitz MS,O'Connor DT

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The renin-angiotensin system (RAS) plays a major role in promoting left ventricular (LV) remodeling in essential hypertension. We designed a controlled, randomized pilot study aimed to test the hypothesis that the dual RAS blockade with angiotensin-converting enzyme (ACE) inhibitor (ACEi) + angiotensin II re...

journal_title：American journal of hypertension

authors： Grandi AM,Solbiati F,Laurita E,Maresca AM,Nicolini E,Marchesi C,Gianni M,Guasti L,Venco A

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Insulin resistance (IR) and the metabolic syndrome (MetS) may contribute to cardiovascular risk in chronic kidney disease (CKD). We examine the association between IR and vascular function in CKD. Furthermore, we define the prevalence of MetS and examine the association between defining MetS and vascular fun...

journal_title：American journal of hypertension

authors： Chan DT,Watts GF,Irish AB,Ooi EM,Dogra GK

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Hypertension varies in prevalence among race/ethnic groups in the United States. Within-ethnic group differences associated with acculturation have been less frequently examined. We studied the association of three measures of acculturation (language spoken at home, place of birth, and years living in the US...

journal_title：American journal of hypertension

authors： Moran A,Diez Roux AV,Jackson SA,Kramer H,Manolio TA,Shrager S,Shea S

更新日期：2007-04-01 00:00:00

abstract：:The effects of increased dietary calcium intake on blood pressure and arterial function were investigated in one-kidney deoxycorticosterone-salt hypertensive Wistar rats. The calcium content of the control diet was 1.1%, and that of the high calcium diet, 2.5%. During the 10-week study calcium supplementation markedly...

journal_title：American journal of hypertension

authors： Mäkynen H,Arvola P,Vapaatalo H,Pörsti I

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Hypertensive disorders of pregnancy, including preeclampsia (PE), affect approximately 7-10% of pregnancies in the US. Clinical and experimental studies strongly suggest that the maternal immune system plays a role in the development of these disorders; however, few therapeutic options exist aside from deliv...

journal_title：American journal of hypertension

authors： Tinsley JH,Chiasson VL,South S,Mahajan A,Mitchell BM

更新日期：2009-10-01 00:00:00

abstract：:Thromboembolic complications such as ischemic stroke and myocardial infarction are significantly more frequent in patients with arterial hypertension. From the available intervention studies, it appears that pharmacologic treatment of hypertension-at least with diuretics and beta-blockers-may more effectively protect ...

journal_title：American journal of hypertension

authors： Lottermoser K,Weisser B,Hertfelder HJ,Wöstmann B,Vetter H,Düsing R

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Differences between the antihypertensive responses to drug therapy measured by office blood pressure (OBP) and ambulatory blood pressure monitoring (ABPM) techniques have been noted but rarely analyzed. We studied whether the OBP and 24-h ABPM responses to hydrochlorothiazide differ and, if so, the relevance...

journal_title：American journal of hypertension

authors： Finkielman JD,Schwartz GL,Chapman AB,Boerwinkle E,Turner ST

更新日期：2005-03-01 00:00:00