当前位置： SCI文献检索 > AMERICAN JOURNAL OF HYPERTENSION期刊下所有文献 > Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study.

Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study.

Abstract：

BACKGROUND:Complement factor H (CFH) is a plasma protein that is essential in the regulation of the alternative complement pathway and has been implicated as taking part in complement inhibition in atherogenesis. We evaluated the association of the Y402H polymorphism with incident coronary heart disease (CHD), incident ischemic stroke, and carotid artery wall thickness (intima-media thickness (IMT)) in the Atherosclerosis Risk in Communities (ARIC) cohort. METHODS:Incident ischemic stroke and CHD were identified through annual telephone calls and hospital and death certificate surveillance. Carotid IMT was measured by means of high-resolution B-mode ultrasound. Four hundred eighty-three validated ischemic stroke and 1,544 CHD events were identified. Because of allele frequency differences between whites and African Americans, analyses were performed separately according to the racial group. RESULTS:The 402HH homozygous genotype was a significant predictor of incident ischemic stroke in whites (hazard rate ratio (HRR) 1.47, 95% confidence interval (CI) 1.05-2.05). Significant interaction effects between genotype and hypertension were observed for CHD in whites and for cIMT in whites and African Americans. In further analyses of incident CHD, genotypes carrying the 402H allele were a significant predictor of incident CHD in whites who had hypertension (402YH: HRR 1.19, 95% CI 1.01-1.40; 402HH: HRR 1.28, 95% CI 1.04-1.57). The 402H allele was also associated with higher cIMT measures for whites in the overall cohort, and for whites with hypertension. CONCLUSION:The CFH 402H allele was associated with an increased risk for incident CHD and ischemic stroke in whites, with the strength and significance of the association dependent upon hypertension status.

journal_name

Am J Hypertens

journal_title

American journal of hypertension

authors

Volcik KA,Ballantyne CM,Braun MC,Coresh J,Mosley TH,Boerwinkle E

doi

10.1038/ajh.2007.81

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

533-8

issue

5

eissn

0895-7061

issn

1941-7225

pii

ajh200781

journal_volume

21

pub_type

杂志文章,多中心研究

相关文献

AMERICAN JOURNAL OF HYPERTENSION文献大全
  • Blood pressure evaluation by noninvasive and traditional methods. Consistencies and discrepancies among photoplethysmomanometry, office sphygmomanometry, and ambulatory monitoring. Effects of blood pressure measurement.

    abstract：:Three hundred eight outpatients referred for hypertension were studied. A continuous beat-to-beat noninvasive recording (Finapres) of blood pressure evaluated the blood pressure increase (9 mm Hg systolic and 4 mm Hg diastolic) induced by office sphygmomanometry. Thereafter, patients underwent a 24-h ambulatory blood ...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/0895-7061(95)00354-1

    authors： Musso NR,Giacchè M,Galbariggi G,Vergassola C

    更新日期：1996-04-01 00:00:00

  • How to explain the differences between renin angiotensin system modulators.

    abstract：:Angiotensin II (Ang II) plays important roles in the development of cardiovascular diseases including hypertension, renal diseases, cardiac hypertrophy, congestive heart failure, and ischemic heart disease. Angiotensin II exerts classic hemodynamic and renal effects, but it is also a local biologically active mediator...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,评审

    doi：10.1016/j.amjhyper.2005.05.005

    authors： Levy BI

    更新日期：2005-09-01 00:00:00

  • The C825T GNB3 polymorphism, independent of blood pressure, predicts cerebrovascular risk at a population level.

    abstract：BACKGROUND:The role of C825T polymorphism of the candidate GNB3 gene in predicting cerebrovascular outcome has been poorly explored in longitudinal setting at a population level. METHODS:In an epidemiological setting, 1,678 men and women from general population were genotyped for C825T polymorphism of GNB3 gene and fo...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1038/ajh.2011.257

    authors： Casiglia E,Tikhonoff V,Boschetti G,Bascelli A,Saugo M,Guglielmi G,Caffi S,Rigoni G,Giordano N,Grasselli C,Martini B,Mazza A,De Lazzari F,Palatini P

    更新日期：2012-04-01 00:00:00

  • Pulsatile hemodynamics and clinical outcomes in acute heart failure.

    abstract：BACKGROUND:The role of pulsatile hemodynamics in the management of patients with acute heart failure syndrome (AHFS) remains to be elucidated. We investigated the changes of the pulsatile hemodynamics along the hospital course of AHFS in relation to short-term outcomes. METHODS:A total of 80 AHFS patients (73.2 ± 14.1...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1038/ajh.2011.26

    authors： Sung SH,Yu WC,Cheng HM,Chuang SY,Wang KL,Huang CM,Chen CH

    更新日期：2011-07-01 00:00:00

  • Impact of Percutaneous Revascularization on Left Ventricular Mass and Its Relationship to Outcome in Hypertensive Patients With Renal Artery Stenosis.

    abstract：BACKGROUND:We investigated the effects of percutaneous transluminal renal angioplasty on left ventricular (LV) mass, and the impact of LV mass reduction on outcomes. METHODS:A total of 144 hypertensive patients with renal artery stenosis (RAS) (mean age 69 years; 22.2% fibromuscular dysplasia (FMD)) who underwent angi...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpaa036

    authors： Iwashima Y,Fukuda T,Horio T,Kusunoki H,Hayashi SI,Kamide K,Kawano Y,Ishimitsu T,Yoshihara F

    更新日期：2020-05-21 00:00:00

  • What time is the "biologic zero hour" of circadian variability?

    abstract：:Most ambulatory blood pressure monitoring (ABPM) studies have used a mechanical clock as the reference time, but there is no biologic background for assuming that midnight by the mechanical clock is zero hour by the biologic clock. The aim of this study was to determine the biologic zero hour as the zero reference tim...

    journal_title：American journal of hypertension

    pub_type： 临床试验,杂志文章

    doi：

    authors： Okutani M,Komori S,Iwasaki H,Mochizuki Y,Kohno I,Mochizuki S,Ishii H,Ijiri H,Tamura K

    更新日期：1997-07-01 00:00:00

  • Adjusting adiposity and body weight measurements for height alters the relationship with blood pressure in children.

    abstract：BACKGROUND:Adiposity measures are associated with increased pediatric blood pressure (BP). However, this correlation can be confounded by the relationship of both variables to height. We evaluated whether adiposity and anthropometric measures were associated with pediatric BP before and after adjusting each value for h...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1038/ajh.2010.82

    authors： Willig AL,Casazza K,Dulin-Keita A,Franklin FA,Amaya M,Fernandez JR

    更新日期：2010-08-01 00:00:00

  • Reduced mRNA and protein content of rho guanine nucleotide exchange factor (RhoGEF) in Bartter's and Gitelman's syndromes: relevance for the pathophysiology of hypertension.

    abstract：BACKGROUND:Activation of RhoA/Rho kinase (ROK) pathway by angiotensin II (Ang II) is involved in the pathophysiology of hypertension and remodeling. In Bartter's and Gitelman's syndrome (BS/GS), the short-term and long-term signaling of Ang II are blunted. The BS/GS have also reduced expression and response on Ang II c...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/j.amjhyper.2005.03.747

    authors： Pagnin E,Semplicini A,Sartori M,Pessina AC,Calò LA

    更新日期：2005-09-01 00:00:00

  • Renal denervation decreases blood pressure in DOCA-treated miniature swine with established hypertension.

    abstract：:The role of renal sympathetic nerve activity (RSNA) in the maintenance phase of essential hypertension has not yet been clearly defined. Renal function and mean arterial pressure (MAP) were studied in four Yucatan miniature swine (YMS) with established DOCA hypertension prior to and for 3 weeks after surgical renal de...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/3.1.62

    authors： O'Hagan KP,Thomas GD,Zambraski EJ

    更新日期：1990-01-01 00:00:00

  • New-Onset Resistant Hypertension in a Newly Diagnosed Prostate Cancer Patient.

    abstract：BACKGROUND:New onset resistant hypertension in a previously stable patient with chronic hypertension should lead to consideration of secondary causes. Electrolyte abnormalities are useful clues for identifying some common causes, especially mineralocorticoid excess. CASE PRESENTATION:We report the case of a 69-year-ol...

    journal_title：American journal of hypertension

    pub_type：

    doi：10.1093/ajh/hpz125

    authors： Klomjit N,Rowan DJ,Kattah AG,Bancos I,Taler SJ

    更新日期：2019-11-15 00:00:00

  • Neural control of renin release.

    abstract：:Among the major mechanisms controlling the renal release of renin, renal nerves are known to exert a direct stimulating action on juxtaglomerular cells that is mediated by beta-adrenoceptors. Activation of the renal nerves also exerts an important permissive role in order to amplify and possibly accelerate responses t...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,评审

    doi：10.1093/ajh/2.2.7s

    authors： Stella A,Golin R,Zanchetti A

    更新日期：1989-02-01 00:00:00

  • Azilsartan improves glycemic status and reduces kidney damage in zucker diabetic fatty rats.

    abstract：BACKGROUND:Azilsartan medoxomil (AZL-M), an angiotensin II receptor blocker, demonstrates antihypertensive and organ protective effects in hypertension. We investigated the efficacy of AZL-M to ameliorate metabolic syndrome and kidney damage associated with type 2 diabetes using Zucker diabetic fatty (ZDF) rats. METHO...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpu016

    authors： Hye Khan MA,Neckář J,Haines J,Imig JD

    更新日期：2014-08-01 00:00:00

  • Serum hepatocyte growth factor concentration is correlated with the forearm vasodilator response in hypertensive patients.

    abstract：:To evaluate the clinical importance of serum hepatocyte growth factor (HGF) concentration, we designed two clinical investigations. The first study analyzed the correlation between serum HGF concentration and clinical arterial stiffness or the vasodilator response to reactive hyperemia in hypertensive patients. The se...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(02)02274-4

    authors： Komai N,Ohishi M,Morishita R,Moriguchi A,Kaibe M,Matsumoto K,Rakugi H,Higaki J,Ogihara T

    更新日期：2002-06-01 00:00:00

  • Sodium retention and volume expansion as mechanisms.

    abstract：:After nephrectomy, the level of arterial pressure is determined by the permitted degree of fluid volume expansion. With kidneys present, the fundamental requirement for fluid volume homeostasis is met by maintaining the balance between sodium and water intake and output. When one-kidney, one-clip (1-K,1-C) hypertensio...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,评审

    doi：10.1093/ajh/4.10.534s

    authors： Ledingham JM

    更新日期：1991-10-01 00:00:00

  • Cytosolic Ca2+ regulation attenuates ANP-induced cGMP response in vascular smooth muscle cells of the SHR.

    abstract：:Cultured vascular smooth muscle cells (VSMCs) of the spontaneously hypertensive rat (SHR) show a higher density (Bmax) of ANP receptors and a blunted cyclic (c) GMP response to the hormone. To explore the idea that a higher cytosolic free Ca2+ (Cai2+) may be responsible for a blunted cGMP response to ANP, we examined ...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/2.2.111

    authors： Nakamura M,Nakamura A,Hatori N,Fine BP,Aviv A

    更新日期：1989-02-01 00:00:00

  • High muscle sympathetic nerve activity is associated with left ventricular dysfunction in treated hypertensive patients.

    abstract：BACKGROUND:The presence of asymptomatic left ventricular diastolic dysfunction (LVDD) in hypertensive patients can be associated with the development of cardiac events. The increase in sympathetic activity may be 1 of the mechanisms that predisposes to this outcome. In this study, we analyzed 2 hypotheses: (i) whether ...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,随机对照试验

    doi：10.1093/ajh/hpt032

    authors： de Souza SB,Rocha JA,Cuoco MA,Guerra GM,Ferreira-Filho JC,Borile S,Krieger EM,Bortolotto LA,Consolim-Colombo FM

    更新日期：2013-07-01 00:00:00

  • Associations of Reservoir-Excess Pressure Parameters Derived From Central and Peripheral Arteries With Kidney Function.

    abstract：BACKGROUND:Central artery reservoir-excess pressure parameters are clinically important but impractical to record directly. However, diastolic waveform morphology is consistent across central and peripheral arteries. Therefore, peripheral artery reservoir-excess pressure parameters related to diastolic waveform morphol...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpaa013

    authors： Armstrong MK,Schultz MG,Picone DS,Black JA,Dwyer N,Roberts-Thomson P,Sharman JE

    更新日期：2020-04-01 00:00:00

  • Differentiation and growth of vascular smooth muscle cells in experimental hypertension.

    abstract：:In this review we have analyzed the present knowledge about the differentiation and growth processes in vascular smooth muscle cells (SMC) in hypertension. The study of smooth muscle (SM) and nonmuscle (NM) myosin isoform expression has permitted us to identify a three-stage specific maturational pathway, namely, feta...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,评审

    doi：10.1093/ajh/7.7.661

    authors： Pauletto P,Sarzani R,Rappelli A,Chiavegato A,Pessina AC,Sartore S

    更新日期：1994-07-01 00:00:00

  • Circulating des-acyl ghrelin improves cardiovascular risk prediction in older hypertensive patients.

    abstract：BACKGROUND:We aimed to assess the predictive value of circulating levels of des-acyl ghrelin, an abundant form of ghrelin in humans, for the risk of cardiovascular disease (CVD) in older hypertensive patients. We simultaneously evaluated other biomarkers, such as high-molecular-weight (HMW) adiponectin, high-sensitivit...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpt232

    authors： Yano Y,Nakazato M,Toshinai K,Inokuchi T,Matsuda S,Hidaka T,Hayakawa M,Kangawa K,Shimada K,Kario K

    更新日期：2014-05-01 00:00:00

  • Echocardiographic comparison of left ventricular structure and function in hypertensive patients with primary aldosteronism and essential hypertension.

    abstract：BACKGROUND:In experimental renovascular hypertension, aldosterone has been implicated in myocardial remodeling and fibrosis, but it is uncertain whether excess aldosterone effects left ventricular structure and function in hypertensive patients. METHODS:Hypertensive patients from the Cardiovascular Center of the New Y...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,多中心研究

    doi：10.1016/s0895-7061(01)02331-7

    authors： Goldkorn R,Yurenev A,Blumenfeld J,Fishman D,Devereux RB

    更新日期：2002-04-01 00:00:00

  • Diuretics for Hypertension: A Review and Update.

    abstract：:This review and update focuses on the clinical features of hydrochlorothiazide (HCTZ), the thiazide-like agents chlorthalidone (CTDN) and indapamide (INDAP), potassium-sparing ENaC inhibitors and aldosterone receptor antagonists, and loop diuretics. Diuretics are the second most commonly prescribed class of antihypert...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,评审

    doi：10.1093/ajh/hpw030

    authors： Roush GC,Sica DA

    更新日期：2016-10-01 00:00:00

  • Central attenuation of baroreflex precedes the development of hypertension in DOCA-salt-treated rats.

    abstract：:To determine whether baroreflex is changed centrally before the development of hypertension in DOCA-salt treated rats, aortic depressor nerve was stimulated electrically 5 days after DOCA-salt treatment in urethane-anesthetized rats: compared with those of sham-operated control rats, blood pressure was not elevated in...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/1.3.23s

    authors： Takeda K,Nakamura Y,Oguro M,Kawasaki S,Hayashi J,Tanabe S,Nakata T,Lee LC,Sasaki S,Nakagawa M

    更新日期：1988-07-01 00:00:00

  • Elevated myocardial repolarization lability and arterial baroreflex dysfunction in healthy individuals with nondipping blood pressure pattern.

    abstract：BACKGROUND:The "nondipping" pattern (NDP) of blood pressure, characterized by the absence of the reduction in blood pressure (BP) that typically takes place during the night time, has been associated with elevated cardiovascular morbidity, including stroke, myocardial infarction, and sudden cardiac-related death. In va...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1038/ajh.2009.252

    authors： Myredal A,Friberg P,Johansson M

    更新日期：2010-03-01 00:00:00

  • Intrarenal arterial network renin content and inhibition by EMD 58265.

    abstract：:The renin content, expressed as nanograms of angiotensin I/hour/milligram, of a rabbit intrarenal arterial network (IAN) was compared to that of renal cortical samples from the same animal. Tissues from six rabbits were studied. Cortical tissue (RC) and an IAN with some glomeruli and attached arterioles (IAN + glomeru...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/0895-7061(94)00073-k

    authors： Birt PC,Zimmerman BG

    更新日期：1995-04-01 00:00:00

  • Association of body mass index with cognitive function in elderly hypertensive Japanese.

    abstract：BACKGROUND:As hypertension, obesity, and leanness are reported to be associated with poor cognitive function, it is possible that obesity or leanness in hypertensive patients may also be associated strongly with poor cognitive function. METHODS:We recruited 184 elderly hypertensive patients comprising 93 very elderly ...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1038/ajh.2008.157

    authors： Sakakura K,Hoshide S,Ishikawa J,Momomura S,Kawakami M,Shimada K,Kario K

    更新日期：2008-06-01 00:00:00

  • Long-Term Changes in Blood Pressure After Pediatric Kidney Transplantation.

    abstract：BACKGROUND:Hypertension presents high prevalence rates following kidney transplantation (Tx). The aims of the present study were to investigate the prevalence and possible risk factors for hypertension and blood pressure (BP) control over time after pediatric kidney Tx, as well as to assess possible effects of hyperten...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpv192

    authors： Stabouli S,Printza N,Dotis J,Gkogka C,Kollios K,Kotsis V,Papachristou F

    更新日期：2016-07-01 00:00:00

  • Blood pressure and angiotensin converting enzyme inhibitor use in hypertensive patients with chronic renal insufficiency.

    abstract：BACKGROUND:Hypertension treatment is important in managing chronic renal insufficiency (CRI). Little is known, however, about the blood pressure (BP) control achieved or the pattern of antihypertensive drug prescription among CRI patients. METHODS:Using computerized medical records, we studied 3,089 adult hypertensive...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(01)02202-6

    authors： Hsu CY,Bates DW,Kuperman GJ,Curhan GC

    更新日期：2001-12-01 00:00:00

  • Bisoprolol and captopril effects on insulin receptor tyrosine kinase activity in essential hypertension.

    abstract：:Angiotension converting enzyme (ACE) inhibitors and beta-blockers have been reported to possess disparate effects on insulin sensitivity. The aim of this study was to study the effects of the selective beta-1 blocker bisoprolol and of the ACE inhibitor captopril on cellular insulin action in hypertensive individuals. ...

    journal_title：American journal of hypertension

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0895-7061(97)00320-8

    authors： Dominguez LJ,Barbagallo M,Jacober SJ,Jacobs DB,Sowers JR

    更新日期：1997-12-01 00:00:00

  • Improved cardiovascular risk stratification by a simple ECG index in hypertension.

    abstract：BACKGROUND:We determined the prognostic value of the Cornell/strain [C/S] index, a simple electrocardiographic (ECG) index for left ventricular hypertrophy (LVH) defined by the presence of either a classic strain pattern or a Cornell voltage (sum of R in aVL + S in V(3)) >2.0 mV in women or 2.4 mV in men, or both. MET...

    journal_title：American journal of hypertension

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0895-7061(03)00912-9

    authors： Verdecchia P,Angeli F,Reboldi G,Carluccio E,Benemio G,Gattobigio R,Borgioni C,Bentivoglio M,Porcellati C,Ambrosio G

    更新日期：2003-08-01 00:00:00

  • Opposite effects of cell growth factors and cicletanine sulfate on the sodium-independent [Cl-/HCO3-] exchange in cultured vascular smooth muscle.

    abstract：:Cicletanine sulfate was tested on bicarbonate-dependent pHi changes in cultured vascular smooth muscle (A10 line). Cicletanine sulfate exhibited double reactivity with regard to the cell alkalinization induced by bicarbonate uptake. The analysis of 11 concentration-response curves revealed a high reactivity component ...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/6.8.674

    authors： Fanous K,Nazaret C,Senn N,Decoopman-Morin E,Allard M,Garay RP

    更新日期：1993-08-01 00:00:00