Opposite effects of cell growth factors and cicletanine sulfate on the sodium-independent [Cl-/HCO3-] exchange in cultured vascular smooth muscle.

abstract：BACKGROUND:Hypertensive disorders of pregnancy, including preeclampsia (PE), affect approximately 7-10% of pregnancies in the US. Clinical and experimental studies strongly suggest that the maternal immune system plays a role in the development of these disorders; however, few therapeutic options exist aside from deliv...

journal_title：American journal of hypertension

authors： Tinsley JH,Chiasson VL,South S,Mahajan A,Mitchell BM

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:In uremic animals, vitamin D receptor (VDR) agonists like paricalcitol (Pc) attenuate cardiac hypertrophy, but this effect has not been replicated consistently in humans with chronic kidney disease. Elevated fibroblast growth factor 23 (FGF23) levels cause cardiac hypertrophy with activation of the myocardia...

journal_title：American journal of hypertension

authors： Czaya B,Seeherunvong W,Singh S,Yanucil C,Ruiz P,Quiroz Y,Grabner A,Katsoufis C,Swaminathan S,Abitbol C,Rodriguez-Iturbe B,Faul C,Freundlich M

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:Central blood pressure (BP) can be used to define hypertension. A central BP approach may be more sensitive than a conventional brachial BP approach in detecting hypertension. We aimed to compare the 2 approaches in estimating the prevalence hypertension in a nationally representative population. METHODS:A ...

journal_title：American journal of hypertension

authors： Chuang SY,Chang HY,Cheng HM,Pan WH,Chen CH

更新日期：2018-02-09 00:00:00

abstract：:The effect of fish oil on potassium efflux and basal tension in aortas from stroke prone spontaneously hypertensive rats (SHRSP) was evaluated. Four-week-old male Wistar-Kyoto rats (WKY) and SHRSP were divided into two groups: one received a 5% corn oil diet; the other a 5% menhaden oil diet. After 15 weeks, mean syst...

journal_title：American journal of hypertension

authors： Smith JM,Paulson DJ,Labak S

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Parathyroid hormone (PTH) stimulates aldosterone secretion in human adrenocortex and is regulated by the renin-angiotensin-aldosterone system. We speculated that measurement of PTH may be a valuable aid in the diagnosis of aldosterone-producing adenoma (APA). METHODS:To test this hypothesis, we recruited 14...

journal_title：American journal of hypertension

authors： Zhang LX,Gu WJ,Li YJ,Wang Y,Wang WB,Wang AP,Shen L,Zang L,Yang GQ,Lu ZH,Dou JT,Mu YM

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Although insulin resistance (IR) is thought to be related to vascular dysfunction, the difference in the relationship of IR to microvasculature and macrovasculature reactivity has not yet been clarified. The present study was conducted to clarify whether the IR is more closely related to the macrovasculature...

journal_title：American journal of hypertension

authors： Yoshida M,Tomiyama H,Yamada J,Matsumoto C,Odaira M,Shiina K,Yamashina A

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Matrix Gla protein (MGP) is a vascular calcification inhibitor dependent upon vitamin K for activation. Evidence suggests that elevated plasma inactive MGP levels (desphospho-uncarboxylated MGP, dp-ucMGP; indicating poorer vascular vitamin K status) are associated with greater cardiovascular disease (CVD) ri...

journal_title：American journal of hypertension

authors： Fain ME,Kapuku GK,Paulson WD,Williams CF,Raed A,Dong Y,Knapen MHJ,Vermeer C,Pollock NK

更新日期：2018-05-07 00:00:00

abstract：BACKGROUND:In the United States, roughly one-third of adults have hypertension; another third have prehypertension. The prevalence of hypertension in deaf American Sign Language (ASL) users is unknown. We address this gap through a descriptive study for the prevalence of hypertension in the American Deaf community and ...

journal_title：American journal of hypertension

authors： Simons AN,Moreland CJ,Kushalnagar P

更新日期：2018-10-15 00:00:00

abstract：BACKGROUND:Type B acute aortic dissection (AAD) carries a high short- and midterm mortality rate; however, knowledge related to long-term outcome is largely incomplete. The objective of this study was to identify long-term predictors including antihypertensive medications in type B AAD. METHODS:We conducted a clinical...

journal_title：American journal of hypertension

authors： Sakakura K,Kubo N,Ako J,Fujiwara N,Funayama H,Ikeda N,Nakamura T,Sugawara Y,Yasu T,Kawakami M,Momomura S

更新日期：2009-04-01 00:00:00

abstract：:Recently, an endogenous digitalis-like factor (EDLF) was shown to be stimulated in corticotropin (ACTH) hypertension in the rat. We have shown that mammalian plasma contains a vasoconstrictor Na,K-ATPase inhibitor, which cross-reacts with an antibody to amphibian EDLF, marinobufagenin. In the present experiment, the e...

journal_title：American journal of hypertension

authors： Fedorova OV,Anderson DE,Bagrov AY

更新日期：1998-07-01 00:00:00

abstract：:The altered membrane microviscosity demonstrated in various cells of spontaneously hypertensive rats (SHR) and essential hypertensive (EH) patients has been proposed to play an important role in the pathogenesis of genetic forms of hypertension. The aim of this study was to evaluate possible changes of membrane microv...

journal_title：American journal of hypertension

authors： Le Quan Sang KH,Kunes J,Zicha J,Vincent M,Sassard J,Devynck MA

更新日期：1994-03-01 00:00:00

abstract：:Recently, we described a circulating hypertensive factor, present in the plasma of spontaneously hypertensive rats (SHR). This factor seems to be produced by the parathyroid gland but is not identical to parathyroid hormone (PTH). In view of these findings, we attempted to search for histological differences in parath...

journal_title：American journal of hypertension

authors： Kaneko T,Ohtani R,Lewanczuk RZ,Pang PK

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Epidemiologic analysis of family data on blood pressure (BP) is often compromised by the effects of antihypertensive medications. A review of numerous clinical trials that investigated the effects of BP-lowering medications is summarized here. METHODS:Published clinical trials, including 137 clinical trials...

journal_title：American journal of hypertension

authors： Wu J,Kraja AT,Oberman A,Lewis CE,Ellison RC,Arnett DK,Heiss G,Lalouel JM,Turner ST,Hunt SC,Province MA,Rao DC

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Reactive oxygen species play a key role in the formation of endothelial dysfunction accompanying diabetes mellitus, hypertension, and other cardiovascular diseases. METHOD:This study compares oxidative stress (OS) in Wistar-Kyoto rats (WKY), spontaneously hypertensive rats (SHR), non-insulin-dependent Cohen...

journal_title：American journal of hypertension

authors： Friedman J,Peleg E,Kagan T,Shnizer S,Rosenthal T

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Salt sensitivity of blood pressure (SSBP) increases the risk of cardiovascular complications, and the heritability of SSBP is about 50% in Chinese population. However, studies identifying genes involved in BP responses to acute sodium loading and diuresis shrinkage are still limited. METHOD:A total of 342 e...

journal_title：American journal of hypertension

authors： Liu K,Liu Z,Qi H,Liu B,Wu J,Liu Y,Zhang J,Cao H,Yan Y,He Y,Zhang L

更新日期：2018-03-10 00:00:00

abstract：:Using a new ion selective electrode (ISE) to measure ionized magnesium (IMg2+), we compared levels of IMg2+ with total magnesium (TMg) and serum ionized calcium levels (ICa2+) in umbilical arterial and venous serum of 13 parturients who developed transient hypertension in labor with levels in 38 who remained normotens...

journal_title：American journal of hypertension

authors： Handwerker SM,Altura BT,Royo B,Altura BM

更新日期：1993-06-01 00:00:00

abstract：:In many reports, the prevalence of target organ damage in renovascular hypertension (RVH) appears to be higher than in essential hypertension (EH). Since in most studies the renal artery stenosis is part of a diffuse atherosclerotic disease, it is not known whether these complications are due to RVH itself or to the v...

journal_title：American journal of hypertension

authors： Losito A,Fagugli RM,Zampi I,Parente B,de Rango P,Giordano G,Cao P

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:On the basis of evidence of plasma leptin (LE) effects on cardiovascular system, we assessed possible association of LE and Doppler-derived left ventricular (LV) diastolic function in arterial hypertension. METHODS:Doppler echocardiography, blood sample for fasting plasma LE levels, and euglycemic hyperinsu...

journal_title：American journal of hypertension

authors： Galderisi M,Tagliamonte MR,D'Errico A,Carella C,Varricchio G,Mondillo S,de Divitiis O,Paolisso G

更新日期：2001-10-01 00:00:00

abstract：:Responses of renin release and blood pressure to aspirin DL-lysine (ASP) were examined to find out if the responses could help in the differentiation between unilateral renovascular hypertension (RVH) and hyperreninemic essential hypertension (EHT). The two studies involved ten patients with unilateral RVH, eight with...

journal_title：American journal of hypertension

authors： Imanishi M,Ohta M,Kawamura M,Akabane S,Matsushima Y,Kuramochi M,Kojima S,Kimura K,Takamiya M,Ito K

更新日期：1991-09-01 00:00:00

abstract：:The objective of this study was to test the relationship between neurologic and microvascular complications of type 1 diabetes mellitus. It was hypothesized that the mechanisms operative in autonomic dysfunction seen in diabetic patients with microangiopathy play a role in the rapidity of progression to renal failure....

journal_title：American journal of hypertension

authors： Weinrauch LA,Kennedy FP,Gleason RE,Keough J,D'Elia JA

更新日期：1998-03-01 00:00:00

abstract：:To evaluate the possible physiologic role of atrial natriuretic factor (ANF) in the observed dissociation of aldosterone secretion from the renin-angiotensin system during hypoxic exercise, 12 untrained men, ages 18 to 24, were studied on two separate days for 30 min during hypoxic (16% O2) and normoxic (room air) exe...

journal_title：American journal of hypertension

authors： Lawrence DL,Shenker Y

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:It is unclear whether serum uric acid (SUA) is associated with development of new-onset diabetes (NOD) in patients with hypertension and left ventricular hypertrophy (LVH). The aim of the present investigation was to test the hypothesis that SUA predicts development of NOD in these patients. METHODS:In the ...

journal_title：American journal of hypertension

authors： Wiik BP,Larstorp AC,Høieggen A,Kjeldsen SE,Olsen MH,Ibsen H,Lindholm L,Dahlöf B,Devereux RB,Okin PM,Wachtell K

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:The X-linked angiotensin II type-2 receptor (AT2R) gene 1675G/A polymorphism is located in the short intron 1 of the AT2R gene within a sequence motif conforming to a splice branch site. AT2R is expressed in the human retina, but no previous study examined the association between retinal microvascular phenot...

journal_title：American journal of hypertension

authors： Liu YP,Kuznetsova T,Thijs L,Jin Y,Schmitz B,Brand SM,Brand E,Manunta P,Bianchi G,Struijker-Boudier H,Staessen JA

更新日期：2011-12-01 00:00:00

abstract：:In an in-depth examination to better define the renal effects of mild hypertension, we used urinary proteins to indicate damage to the glomerulus (albumin), tubular reabsorption capability (retinol-binding protein), and turnover of tubular tissue (alanine aminopeptidase and N-acetyl-beta-D-glucosaminidase) in a group ...

journal_title：American journal of hypertension

authors： Mueller PW,Hall WD,Caudill SP,MacNeil ML,Arepally A

更新日期：1995-11-01 00:00:00

abstract：:Antihypertensive drugs are often initiated and adjusted over a period of weeks to months. It is not clear whether the time and inconvenience of this approach is necessary. We studied whether or not drug adjustment over several days in the context of a physician-nurse team could produce a durable blood pressure benefit...

journal_title：American journal of hypertension

authors： Canzanello VJ,Jensen PL,Hunder I

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:A resequencing study of renal epithelial sodium channel (ENaC) genes was conducted to identify rare variants associated with blood pressure (BP) salt-sensitivity. METHODS:The Genetic Epidemiology Network of Salt-Sensitivity (GenSalt) study was conducted among 1,906 participants who underwent a 7-day low-sod...

journal_title：American journal of hypertension

authors： Gu X,Gu D,He J,Rao DC,Hixson JE,Chen J,Li J,Huang J,Wu X,Rice TK,Shimmin LC,Kelly TN

更新日期：2018-01-12 00:00:00

abstract：:Vasodilation is impaired in various conditions, such as hypercholesterolemia and tobacco use. We evaluated brachial artery flow-mediated vasodilation (FMD) after blood pressure (BP) cuff occlusion using high-resolution B-mode ultrasound in 20 alcoholics, without any coexisting conditions such as smoking, hypertension,...

journal_title：American journal of hypertension

authors： Maiorano G,Bartolomucci F,Contursi V,Minenna FS,Di Mise R,Palasciano A,Allegrini B,Amoruso M,Kozàkovà M

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Marinobufagenin (MBG) is an endogenous Na/K-ATPase inhibitor, a natriuretic and a vasoconstrictor. MBG is implicated in salt-sensitive hypertension, cardiac hypertrophy, and initiate the pro-fibrotic signaling. Previously it was demonstrated that immunoneutralization of an endogenous MBG by 3E9 anti-MBG-anti...

journal_title：American journal of hypertension

authors： Grigorova YN,Juhasz O,Zernetkina V,Fishbein KW,Lakatta EG,Fedorova OV,Bagrov AY

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:While obesity is a leading risk factor for preeclampsia, the mechanisms whereby obese women are more susceptible to pregnancy-induced hypertension are unclear. As high-fat diet (HFD) is an important contributor to the development of obesity, we tested the hypothesis that pregnant rats on HFD have hypertensio...

journal_title：American journal of hypertension

authors： Palei AC,Spradley FT,Granger JP

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:There are no comprehensive guidelines on management of hypertensive emergency (HTNE) and complications. Despite advances in antihypertensive medications HTNE is accompanied with significant morbidity and mortality. METHODS:We queried the 2002-2012 nationwide inpatient sample database to identify patients wi...

journal_title：American journal of hypertension

authors： Shah M,Patil S,Patel B,Arora S,Patel N,Garg L,Agrawal S,Jacobs L,Steigerwalt SP,Martinez MW

更新日期：2017-07-01 00:00:00