当前位置： SCI文献检索 > AMERICAN JOURNAL OF HYPERTENSION期刊下所有文献 > Determinants of long-term mortality in patients with type B acute aortic dissection.

Determinants of long-term mortality in patients with type B acute aortic dissection.

Abstract：

BACKGROUND:Type B acute aortic dissection (AAD) carries a high short- and midterm mortality rate; however, knowledge related to long-term outcome is largely incomplete. The objective of this study was to identify long-term predictors including antihypertensive medications in type B AAD. METHODS:We conducted a clinical follow-up study on 202 type B AAD patients. Univariate and multivariate Cox regression analyses were performed to identify predictors of mortality. RESULTS:There were 44 postdischarge deaths in 202 consecutive type B AAD patients with a median follow-up of 55 months. In univariate Cox regression analysis, age (10 year incremental: hazard ratio (HR) 1.82, 95% confidence interval (CI) 1.35-2.46, P < 0.0001), previous myocardial infarction or angina pectoris (HR 3.93, 95% CI 1.72-8.99, P = 0.001), and impaired renal function (HR 4.90, 95% CI 2.48-9.65, P < 0.0001) were predictors of death. Calcium channel blockers (CCBs), beta-blockers, and angiotensin-converting enzyme (ACE) inhibitors as antihypertensive medications at discharge were predictors of increased survival. In multivariate Cox regression analysis, CCBs were a significant predictor of increased survival (vs. no antihypertensive medication at discharge: HR 0.38, 95% CI 0.15-0.97, P = 0.04). Impaired renal function was a significant predictor of death (HR 3.41, 95% CI 1.58-7.33, P = 0.002). No antihypertensive medication at discharge group was significantly associated with increased mortality (vs. 1 class of antihypertensive medication: HR 9.51, 95% CI 1.85-48.79, P = 0.007). CONCLUSIONS:Impaired renal function was a predictor for adverse outcome in patients with type B AAD. The use of CCBs as antihypertensive medication at discharge was associated with increased survival.

journal_name

Am J Hypertens

journal_title

American journal of hypertension

authors

Sakakura K,Kubo N,Ako J,Fujiwara N,Funayama H,Ikeda N,Nakamura T,Sugawara Y,Yasu T,Kawakami M,Momomura S

doi

10.1038/ajh.2009.5

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

371-7

issue

4

eissn

0895-7061

issn

1941-7225

pii

ajh20095

journal_volume

22

pub_type

杂志文章

相关文献

AMERICAN JOURNAL OF HYPERTENSION文献大全
  • Acute Blood Pressure and Cardiovascular Effects of Near-Roadway Exposures With and Without N95 Respirators.

    abstract：BACKGROUND:The risk for cardiovascular events increases within hours of near-roadway exposures. We aimed to determine the traffic-related air pollution (TRAP) and biological mechanisms involved and if reducing particulate matter <2.5 µm (PM2.5) inhalation is protective. METHODS:Fifty healthy-adults underwent multiple ...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,随机对照试验

    doi：10.1093/ajh/hpz113

    authors： Morishita M,Wang L,Speth K,Zhou N,Bard RL,Li F,Brook JR,Rajagopalan S,Brook RD

    更新日期：2019-10-16 00:00:00

  • Low-dose antihypertensive combination therapy: its rationale and role in cardiovascular risk management.

    abstract：:Antihypertensive monotherapy, although commonly used, does not address the multifactorial nature of hypertension as a disease with many pathways. Using more than one drug makes more therapeutic sense because combination agents cover more than one pathway, yet the use of drugs in tandem is typically relegated to more p...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(99)00112-0

    authors： Neutel JM

    更新日期：1999-08-01 00:00:00

  • Feasibility of home blood pressure measurement in elderly individuals: cross-sectional analysis of a population-based sample.

    abstract：BACKGROUND:Home blood pressure measurement (HBPM) is recommended by hypertension guidelines, particularly in the elderly. However, feasibility of HBPM in this age group has not been fully established. Our objective was therefore to assess HBPM feasibility in elderly individuals of the general population. METHODS:After...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,多中心研究

    doi：10.1038/ajh.2012.121

    authors： Cacciolati C,Tzourio C,Dufouil C,Alpérovitch A,Hanon O

    更新日期：2012-12-01 00:00:00

  • Blood pressure control in the hypertension clinic.

    abstract：BACKGROUND:One effort to improve hypertension care in the United States is the development of the "Hypertension Specialist" program with appropriate training and certification of individual physicians. METHODS:We examined the impact of a hypertension clinic on blood pressure (BP) levels and control. RESULTS:By one ye...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(03)01030-6

    authors： Bansal N,Tendler BE,White WB,Mansoor GA

    更新日期：2003-10-01 00:00:00

  • The association of nephrolithiasis with hypertension and obesity: a review.

    abstract：:Kidney stones affect hypertensive patients disproportionately compared to normotensive individuals. On the other hand, some prospective data suggest that a history of nephrolithiasis was associated with a greater tendency to develop hypertension. Newer epidemiologic data also link obesity and diabetes, features of the...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,评审

    doi：10.1038/ajh.2007.62

    authors： Obligado SH,Goldfarb DS

    更新日期：2008-03-01 00:00:00

  • Correlation between peripheral blood pressure and pulse-wave velocity values in the institutionalized elderly persons 80 years of age and older: the PARTAGE study.

    abstract：BACKGROUND:Carotid-femoral pulse-wave velocity (PWV) provides a comprehensive noninvasive indication of arterial stiffness, and is now established as a strong marker of cardiovascular disease (CVD). The correlation between peripheral blood pressure (BP) and PWV and their respective influences on mortality have been poo...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,多中心研究

    doi：10.1093/ajh/hps042

    authors： Miljkovic D,Perret-Guillaume C,Alla F,Salvi P,Erpelding ML,Benetos A

    更新日期：2013-02-01 00:00:00

  • Gender differences in insulin-stimulated glucose utilization among African-Americans.

    abstract：:The purpose of this study was to determine whether there are gender differences in plasma insulin levels or insulin resistance in young adult African-Americans. Male (n = 53) and female (n = 45) subjects (age 23 to 28 years) included normotensives (N, blood pressure [BP] < 135/85 mm Hg) and borderline hypertensives (B...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/7.11.948

    authors： Falkner B,Hulman S,Kushner H

    更新日期：1994-11-01 00:00:00

  • Asymmetric dimethylarginine (ADMA) has a role in regulating systemic vascular tone in young healthy subjects: the cardiovascular risk in young Finns study.

    abstract：BACKGROUND:This study was designed to evaluate whether plasma asymmetric dimethylarginine (ADMA) has any role in predicting hemodynamic responses in clinically healthy young subjects. ADMA, as an endogenous nitric oxide (NO) synthase inhibitor, has been demonstrated to associate with hypertension and vascular reactivit...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1038/ajh.2008.215

    authors： Päivä H,Kähönen M,Lehtimäki T,Raitakari OT,Jula A,Viikari J,Alfthan G,Juonala M,Laaksonen R,Hutri-Kähönen N

    更新日期：2008-08-01 00:00:00

  • Pulsatile hemodynamics and clinical outcomes in acute heart failure.

    abstract：BACKGROUND:The role of pulsatile hemodynamics in the management of patients with acute heart failure syndrome (AHFS) remains to be elucidated. We investigated the changes of the pulsatile hemodynamics along the hospital course of AHFS in relation to short-term outcomes. METHODS:A total of 80 AHFS patients (73.2 ± 14.1...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1038/ajh.2011.26

    authors： Sung SH,Yu WC,Cheng HM,Chuang SY,Wang KL,Huang CM,Chen CH

    更新日期：2011-07-01 00:00:00

  • Effects of isradipine on endothelin-induced constriction of myometrial arteries in normotensive pregnant women.

    abstract：:The results of our previous studies suggested that endothelin-1 (ET-1) might be contributory to the impaired uteroplacental blood flow seen in preeclampsia. The aim of this study was to investigate the in vitro influence of isradipine on ET-1-induced contraction of myometrial resistance arteries from pregnant women, a...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/7.7.50s

    authors： Kublickiene KR,Wolff K,Kublickas M,Lindblom B,Lunell NO,Nisell H

    更新日期：1994-07-01 00:00:00

  • Arterial stiffness and fetal growth in normotensive pregnancy.

    abstract：BACKGROUND:Normal pregnancy is characterized by a decrease in peripheral resistance and generalized vasodilation resulting in plasma volume expansion, which is associated with intrauterine growth. Stiffness of the arterial system may be a measure of the degree of plasma volume expansion. Pulse wave velocity (PWV), meas...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/j.amjhyper.2004.10.020

    authors： Elvan-Taspinar A,Franx A,Bots ML,Koomans HA,Bruinse HW

    更新日期：2005-03-01 00:00:00

  • Adiposity and blood pressure in South Asian children and adolescents in Karachi.

    abstract：BACKGROUND:The association of adiposity during childhood with future risk of elevated blood pressure (BP) in South Asian children is not known. We aimed to investigate the relationship between waist circumference (WC) and body mass index (BMI) with BP over a 2-year period, independent of the baseline BP. METHODS:We an...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,随机对照试验

    doi：10.1038/ajh.2011.67

    authors： Almas A,Jafar TH

    更新日期：2011-08-01 00:00:00

  • Blood pressure, low-density lipoprotein cholesterol, and incidences of coronary artery disease and ischemic stroke in Japanese: the Suita study.

    abstract：BACKGROUND:Blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C) are risk factors for coronary artery disease (CAD) and ischemic stroke. However, the hazards of their coexistence are not fully understood in Asian populations. We investigated whether the relationship between BP and cardiovascular disease (...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/hpu059

    authors： Tsukinoki R,Okamura T,Watanabe M,Kokubo Y,Higashiyama A,Nishimura K,Takegami M,Murakami Y,Okayama A,Miyamoto Y

    更新日期：2014-11-01 00:00:00

  • A cross-national comparative study of blood pressure and hypertension between English and Dutch South-Asian- and African-origin populations: the role of national context.

    abstract：BACKGROUND:We compare patterns of blood pressure (BP) and prevalence of hypertension between white-Dutch and their South-Asian and African minority groups with their corresponding white-English and their South-Asian and African ethnic minority groups; and the contribution of physical activity, body sizes, and socioecon...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,多中心研究

    doi：10.1038/ajh.2010.39

    authors： Agyemang C,Kunst A,Bhopal R,Zaninotto P,Unwin N,Nazroo J,Nicolaou M,Redekop WK,Stronks K

    更新日期：2010-06-01 00:00:00

  • Hemodynamics of seasonal adaptation.

    abstract：:To investigate the possibility that seasonal adaptation requires significant hemodynamic changes, 5 normotensive and 21 mildly hypertensive subjects were followed through 4 seasons for changes in systemic hemodynamics and sympathetic nervous activity. In the upright position wintertime blood pressures increased by 3% ...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/3.5.405

    authors： Izzo JL Jr,Larrabee PS,Sander E,Lillis LM

    更新日期：1990-05-01 00:00:00

  • The relation between peripheral vascular structure, left ventricular hypertrophy, and ambulatory blood pressure in essential hypertension.

    abstract：:The relations between left ventricular mass (LVM), peripheral resistance artery structure, and ambulatory BP were studied in 83 patients with previously untreated or poorly regulated essential hypertension and 20 healthy controls of similar age and sex. LVM was assessed by echocardiography. Signs of left ventricular h...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/0895-7061(95)00220-0

    authors： Sihm I,Schroeder AP,Aalkjaer C,Holm M,Mørn B,Mulvany M,Thygesen K,Lederballe O

    更新日期：1995-10-01 00:00:00

  • Impaired vasodilator capacity and exaggerated pressor response to isometric exercise in subjects with family history of hypertension.

    abstract：:The nature of the cardiovascular response to isometric exercise is still debated. An adequate blood supply to exercising muscles at the onset of contraction seems to be an important factor controlling the extent of pressor response to isometric contraction. In comparison to normotensive subjects without familiar hyper...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/1.3.106s

    authors： Borghi C,Costa FV,Boschi S,Ambrosioni E

    更新日期：1988-07-01 00:00:00

  • Arterial stiffening, wave reflection, and inflammation in habitually exercising systemic lupus erythematosus patients.

    abstract：BACKGROUND:Chronic systemic inflammation has been implicated in the pathogenesis of hypertension and cardiovascular disease. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by chronic inflammation and an increased risk for cardiovascular disease. Currently few studies have evaluated the potent...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1038/ajh.2011.143

    authors： Barnes JN,Nualnim N,Sugawara J,Sommerlad SM,Renzi CP,Tanaka H

    更新日期：2011-11-01 00:00:00

  • Circadian blood pressure overswinging in a physically fit, normotensive African American woman.

    abstract：:Ambulatory blood pressure (BP) and heart rate (HR) were measured in a physically fit, normotensive postmenopausal African American woman, before and after 15 weeks of aerobic training. Mean BP, HR, and HR variability were normal at the outset and were further improved by training. Training had no effect on circadian B...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(02)02973-4

    authors： Borer KT,Cornelissen G,Halberg F,Brook R,Rajagopalan S,Fay W

    更新日期：2002-09-01 00:00:00

  • Hypertension in kidney transplant recipients. Effect on long-term renal allograft survival.

    abstract：:To examine the effects of hypertension on renal graft function, we studied the clinical course of 144 kidney transplant recipients who had functioning grafts for three to 13 years. The patients were divided into three groups: normotensive (n = 32), controlled hypertensive (n = 49) and uncontrolled hypertensive group (...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/2.5.341

    authors： Cheigh JS,Haschemeyer RH,Wang JC,Riggio RR,Tapia L,Stenzel KH,Rubin AL

    更新日期：1989-05-01 00:00:00

  • Effect of amlodipine on mesangial cell proliferation and protein synthesis.

    abstract：:Mesangial cells in the glomerulus have several important physiological functions, as has been demonstrated by past research. Platelet derived growth factor, thrombin, endothelin, and angiotensin II have all been shown to affect mesangial cell growth and protein synthesis. First generation Ca channel blockers also have...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：

    authors： Shultz PJ,Raij L

    更新日期：1992-12-01 00:00:00

  • Antihypertensive and humoral effects of nifedipine in essential hypertension uncontrolled by hydrochlorothiazide alone.

    abstract：:This double-blind placebo controlled study investigated the antihypertensive and humoral effects of nifedipine capsules in patients with essential hypertension inadequately controlled (seated diastolic blood pressure greater than or equal to 95 mm Hg) by hydrochlorothiazide (HCTZ) alone. Nifedipine acutely (first dose...

    journal_title：American journal of hypertension

    pub_type： 临床试验,杂志文章

    doi：10.1093/ajh/2.11.828

    authors： Opsahl JA,Halstenson CE,Abraham PA

    更新日期：1989-11-01 00:00:00

  • Angiotensin II upregulates transforming growth factor-beta type I receptor on rat vascular smooth muscle cells.

    abstract：:Angiotensin II (Ang II) and transforming growth factor-beta (TGF-beta) modulate cell growth and metabolism. Our objective was to evaluate the effect of Ang II on the characteristics and expression of TGF-beta receptors on vascular smooth muscle cells (VSMC) from Wistar-Kyoto rats. The addition of TGF-beta1 elicited a ...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(99)00152-1

    authors： Fukuda N,Hu WY,Kubo A,Kishioka H,Satoh C,Soma M,Izumi Y,Kanmatsuse K

    更新日期：2000-02-01 00:00:00

  • Reduced cardiovascular reactivity to stress but not feeding in renin enhancer knockout mice.

    abstract：BACKGROUND:We have recently shown that the renin enhancer, a regulatory element of renin gene transcription, is important in the long-term control of basal blood pressure (BP). In this study, we examined whether the renin enhancer deficit alters the acute pressor response to emotional stress in mice. METHODS:Under flu...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/j.amjhyper.2007.02.010

    authors： Jackson K,Head GA,Morris BJ,Chin-Dusting J,Jones E,La Greca L,Mayorov DN

    更新日期：2007-08-01 00:00:00

  • Effects of calcium channel and renin-angiotensin system blockade on intravascular and neurohormonal mechanisms of hypertensive vascular disease.

    abstract：:Several classes of antihypertensive drugs have been shown to improve vascular function through mechanisms other than reducing blood pressure (BP) alone. Certain dihydropyridine calcium channel blockers (CCBs) and inhibitors of the renin-angiotensin system (RAS) increase nitric oxide (NO) bioavailability and decrease o...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,评审

    doi：10.1038/ajh.2008.258

    authors： Mizuno Y,Jacob RF,Mason RP

    更新日期：2008-10-01 00:00:00

  • No evidence of a relation between 11beta-hydroxysteroid dehydrogenase type 2 activity and salt sensitivity.

    abstract：BACKGROUND:The ratio of urinary concentrations of tetrahydrocortisol plus allotetrahydrocortisol to tetrahydrocortisone [(THF + ATHF)/THE] reflects the activity of the enzyme 11beta-hydroxysteroid dehydrogenase type 2 (11BHSD2), which converts cortisol to cortisone in the kidney and thereby protects the mineralocortico...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1016/s0895-7061(03)00981-6

    authors： Melander O,Frandsen E,Groop L,Hulthén UL

    更新日期：2003-09-01 00:00:00

  • Prevention and Treatment of Hypertension Study (PATHS). Rationale and design.

    abstract：:Alcohol consumption has been recognized as an important correlate of blood pressure in many epidemiologic studies, but few interventional studies have been conducted to examine the effect of a reduction in alcohol intake on blood pressure. Because these studies have usually included few subjects and been of short dura...

    journal_title：American journal of hypertension

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1093/ajh/7.9.814

    authors： Cushman WC,Cutler JA,Bingham SF,Harford T,Hanna E,Dubbert P,Collins JF,Dufour M,Follman D,Allender PS

    更新日期：1994-09-01 00:00:00

  • Enhanced 45Ca2+ efflux in cultured vascular smooth muscle cells from spontaneously hypertensive rats.

    abstract：:Ca2+ efflux from cultured vascular smooth muscle cells (VSMC) consists of two mechanisms: one is dependent on extracellular sodium, mediated by the Na(+)-Ca2+ exchange (Na+o-dependent Ca2+ efflux), and the other is independent of extracellular sodium but is mediated by the Ca(2+)-pump (Na+o-independent Ca2+ efflux). I...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/7.7.597

    authors： Chen S,Roufogalis BD

    更新日期：1994-07-01 00:00:00

  • Methods and devices for measuring arterial compliance in humans.

    abstract：:This review analyses methods and devices used worldwide to evaluate the arterial stiffness. Three main methodologies are based upon analysis of pulse transit time, of wave contour of the arterial pulse, and of direct measurement of arterial geometry and pressure, corresponding to regional, systemic and local determina...

    journal_title：American journal of hypertension

    pub_type： 杂志文章,评审

    doi：10.1016/s0895-7061(02)02962-x

    authors： Pannier BM,Avolio AP,Hoeks A,Mancia G,Takazawa K

    更新日期：2002-08-01 00:00:00

  • Erythrocyte sodium concentration and 86Rb uptake in weanling Dahl rats.

    abstract：:Alterations in Na, K ATPase pump activity as well as erythrocyte (RBC) intracellular sodium concentration (Nai) have been demonstrated in humans and rats with established hypertension. The contribution of hypertension itself to these changes is unclear. Accordingly, we investigated RBC ion transport and plasma ouabain...

    journal_title：American journal of hypertension

    pub_type： 杂志文章

    doi：10.1093/ajh/2.8.604

    authors： McCormick CP,Hennessy JF,Rauch AL,Buckalew VM Jr

    更新日期：1989-08-01 00:00:00