Impaired vasodilator capacity and exaggerated pressor response to isometric exercise in subjects with family history of hypertension.

abstract：BACKGROUND:Hypertension is a definitive risk factor for stroke. We examined the associations between hypertension subtypes and stroke incidence in rural Chinese adults. METHODS:We conducted a prospective study in a sample of 38,949 rural Chinese adults aged ≥35 years and free from stroke at baseline. The subtypes of h...

journal_title：American journal of hypertension

authors： Sun Z,Han X,Zheng L,Zhang X,Li J,Hu D,Sun Y

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:The renin-angiotensin system (RAS) plays a major role in promoting left ventricular (LV) remodeling in essential hypertension. We designed a controlled, randomized pilot study aimed to test the hypothesis that the dual RAS blockade with angiotensin-converting enzyme (ACE) inhibitor (ACEi) + angiotensin II re...

journal_title：American journal of hypertension

authors： Grandi AM,Solbiati F,Laurita E,Maresca AM,Nicolini E,Marchesi C,Gianni M,Guasti L,Venco A

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Currently, total hyperhomocysteinemia (tHHcy) is a well-known condition linked to a higher risk of vascular disease. Prevalence of HHcy increases in elderly persons as the risk associated with it persists. Because factors can be potentially reduced in the elderly, it is important to carry out epidemiologic s...

journal_title：American journal of hypertension

authors： Janson JJ,Galarza CR,Murúa A,Quintana I,Przygoda PA,Waisman G,Camera L,Kordich L,Morales M,Mayorga LM,Camera MI

更新日期：2002-05-01 00:00:00

abstract：:We sought to determine whether reductions in blood pressure in hypertensives after acute exercise persist for more than the 2 to 3 h found in controlled laboratory settings. Subjects (n = 11) were obese (32 +/- 4% body fat), sedentary (VO2max 27 +/- 4 mL/kg/min) 60 +/- 6-year-old men with stage 1 or 2 essential hypert...

journal_title：American journal of hypertension

authors： Taylor-Tolbert NS,Dengel DR,Brown MD,McCole SD,Pratley RE,Ferrell RE,Hagberg JM

更新日期：2000-01-01 00:00:00

abstract：:During the course of a long-term, prospective, randomized study in 77 hypertensive nephrosclerosis patients, five patients developed evidence suggestive of renal artery stenosis. However, arteriography demonstrated patent renal arteries. The evidence suggestive of renal artery stenosis was: (1) converting-enzyme inhib...

journal_title：American journal of hypertension

authors： Pettinger WA,Mitchell HC,Lee HC,Redman HC

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Hypertension varies in prevalence among race/ethnic groups in the United States. Within-ethnic group differences associated with acculturation have been less frequently examined. We studied the association of three measures of acculturation (language spoken at home, place of birth, and years living in the US...

journal_title：American journal of hypertension

authors： Moran A,Diez Roux AV,Jackson SA,Kramer H,Manolio TA,Shrager S,Shea S

更新日期：2007-04-01 00:00:00

abstract：:The stimulation of autocrine and paracrine factors such as basic fibroblast- (bFGF) and platelet-derived (PDGF) growth factors mediates many of the growth-promoting actions of angiotensin II. The aim of this study was to evaluate the effect of chronic AT1-receptor blockade on plasma endothelin-1 (ET-1) and growth fact...

journal_title：American journal of hypertension

authors： Cottone S,Vadalà A,Vella MC,Nardi E,Mulé G,Contorno A,Riccobene R,Cerasola G

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Hypertension treatment is important in managing chronic renal insufficiency (CRI). Little is known, however, about the blood pressure (BP) control achieved or the pattern of antihypertensive drug prescription among CRI patients. METHODS:Using computerized medical records, we studied 3,089 adult hypertensive...

journal_title：American journal of hypertension

authors： Hsu CY,Bates DW,Kuperman GJ,Curhan GC

更新日期：2001-12-01 00:00:00

abstract：:Left ventricular hypertrophy (LVH) is more prevalent in black than white hypertensives, but this difference is greater when identified by electrocardiography (ECG) than by echocardiography. We evaluated the proposal that current ECG criteria for LVH are less specific, and therefore, less useful, in blacks than whites....

journal_title：American journal of hypertension

authors： Chapman JN,Mayet J,Chang CL,Foale RA,Thom SA,Poulter NR

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:This study was designed to evaluate whether plasma asymmetric dimethylarginine (ADMA) has any role in predicting hemodynamic responses in clinically healthy young subjects. ADMA, as an endogenous nitric oxide (NO) synthase inhibitor, has been demonstrated to associate with hypertension and vascular reactivit...

journal_title：American journal of hypertension

authors： Päivä H,Kähönen M,Lehtimäki T,Raitakari OT,Jula A,Viikari J,Alfthan G,Juonala M,Laaksonen R,Hutri-Kähönen N

更新日期：2008-08-01 00:00:00

abstract：:Twenty-four-hour ambulatory blood pressure measurements (ABPM) are likely to eliminate the stress of visits and observer bias in office blood pressure (BP) recordings, allow consideration of the circadian variability in BP, and correlate well with target organ damage. To define the prevalence of "white coat" hypertens...

journal_title：American journal of hypertension

authors： Khoury S,Yarows SA,O'Brien TK,Sowers JR

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Recently, some investigators have shown that telmisartan, an angiotensin II (Ang II)-receptor blocker (ARB), is a partial agonist of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma). We investigate whether telmisartan improves cardiovascular remodeling associated with the production of endot...

journal_title：American journal of hypertension

authors： Kobayashi N,Ohno T,Yoshida K,Fukushima H,Mamada Y,Nomura M,Hirata H,Machida Y,Shinoda M,Suzuki N,Matsuoka H

更新日期：2008-05-01 00:00:00

abstract：:We have explored the effect of verapamil on renal hemodynamics and the renin-aldosterone system in ten patients with chronic renal disease and hypertension before and after 3 months of therapy. The mean +/- SEM glomerular filtration rates were 55 +/- 7 mL/min pre- and 55 +/- 8 mL/min posttherapy; the renal plasma flow...

journal_title：American journal of hypertension

authors： Lenz T,Müller FB,Sotelo JE,Laragh JH,August P

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Increases in blood pressure were reported in overworked public workers following the Mid-Niigata earthquake. This study aimed to compare blood pressure changes between public employees and the general population after the Great East Japan Earthquake of March 2011. METHODS:We analyzed 1,776 individuals from ...

journal_title：American journal of hypertension

authors： Konno S,Hozawa A,Munakata M

更新日期：2013-09-01 00:00:00

abstract：:Essential hypertension is often accompanied by abnormalities of the coagulation/fibrinolytic system, predisposing to a procoagulant state. The aim of the present study was to compare the effects of atenolol (beta1-blocker agent) and irbesartan (angiotensin II type 1 receptor antagonist) on plasma levels of hemostatic/...

journal_title：American journal of hypertension

authors： Makris TK,Stavroulakis GA,Krespi PG,Hatzizacharias AN,Triposkiadis FK,Tsoukala CG,Votteas VV,Kyriakidis MK

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Ionized magnesium levels are elevated in fetal blood compared with maternal blood, suggesting that the placenta may possess an active transport mechanism for magnesium. In the present study, we sought to determine the existence of an active transport mechanism for magnesium in the placenta using cultured tro...

journal_title：American journal of hypertension

authors： Standley PR,Standley CA

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:This study examines the interrelationship between gestational weight gain, pre-pregnancy body mass index (BMI), race/ethnicity, and their association with hypertensive disorders during pregnancy (HDP). METHODS:Data from the 2004-2011 national Pregnancy Risk Assessment Monitoring System (PRAMS) were analyzed...

journal_title：American journal of hypertension

authors： Masho SW,Urban P,Cha S,Ramus R

更新日期：2016-06-01 00:00:00

abstract：:We investigated the effects of 17 beta-estradiol (beta E2), alpha-estradiol (alpha E2), and progesterone (P) on baseline and vasopressin (AVP)-induced [Ca2+]i in human platelets obtained from healthy male and female volunteers. Platelets were treated with beta E2, alpha E2, P, or ethanol vehicle for 30 min at 37 degre...

journal_title：American journal of hypertension

authors： Raman BB,Standley PR,Rajkumar V,Ram JL,Sowers JR

更新日期：1995-02-01 00:00:00

abstract：:Neutral metalloendopeptidase (NEP) inhibitors delay atrial natriuretic factor (ANF) catabolism and potentiate biological responses to ANF. We describe biochemical and pharmacological profiles of a novel NEP inhibitor, SCH 42354 (N-[2(S)-(mercaptomethyl)-3-(2-methylphenyl)-4-oxopropyl]-L-methionine and its orally activ...

journal_title：American journal of hypertension

authors： Watkins RW,Vemulapalli S,Chiu PJ,Foster C,Smith EM,Neustadt B,Haslanger M,Sybertz EJ

更新日期：1993-05-01 00:00:00

abstract：:Despite intense investigation and clinical attention, many challenges remain in the management of the hypertensive patient. It is clear that hypertension remains inadequately controlled worldwide, with the control rate in the United States approximating 27%. Furthermore, several recent studies have underscored that it...

journal_title：American journal of hypertension

authors： Epstein M

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Population-level sociologic studies have suggested that adverse societal conditions may affect fetal viability in a sex-specific manner and thereby modify the ratio of male vs. female babies. This concept suggests that there may exist certain physiologic features in a woman that relate to her likelihood of d...

journal_title：American journal of hypertension

authors： Retnakaran R,Wen SW,Tan H,Zhou S,Ye C,Shen M,Smith GN,Walker MC

更新日期：2017-04-01 00:00:00

abstract：:Ca2+ efflux from cultured vascular smooth muscle cells (VSMC) consists of two mechanisms: one is dependent on extracellular sodium, mediated by the Na(+)-Ca2+ exchange (Na+o-dependent Ca2+ efflux), and the other is independent of extracellular sodium but is mediated by the Ca(2+)-pump (Na+o-independent Ca2+ efflux). I...

journal_title：American journal of hypertension

authors： Chen S,Roufogalis BD

更新日期：1994-07-01 00:00:00

abstract：:Great pathophysiological significance has recently been placed on the association of metabolic abnormalities, such as hyperinsulinemia, insulin resistance, obesity, and frank diabetes mellitus, with essential hypertension and coronary artery disease, and the clinical coincidence of these features has been termed "synd...

journal_title：American journal of hypertension

authors： Resnick LM

更新日期：1993-04-01 00:00:00

abstract：:To elucidate whether postprandial hypotension (PPH) is associated with any diurnal change of blood pressure, ambulatory blood pressure monitoring was performed on 121 hospitalized essential hypertensive patients who received standardized meals. Postprandial change in blood pressure was defined as the difference betwee...

journal_title：American journal of hypertension

authors： Kohara K,Uemura K,Takata Y,Okura T,Kitami Y,Hiwada K

更新日期：1998-11-01 00:00:00

abstract：:The purpose of this study was to determine whether there are gender differences in plasma insulin levels or insulin resistance in young adult African-Americans. Male (n = 53) and female (n = 45) subjects (age 23 to 28 years) included normotensives (N, blood pressure [BP] < 135/85 mm Hg) and borderline hypertensives (B...

journal_title：American journal of hypertension

authors： Falkner B,Hulman S,Kushner H

更新日期：1994-11-01 00:00:00

abstract：:The independent and combined effects of aerobic exercise training (AEX) and weight loss (WL) on blood pressure (BP) and oral glucose tolerance were studied in 97 nondiabetic, sedentary, older men. The men were assigned to either a WL (n = 31), AEX (n = 35), AEX+WL (n = 20) intervention, or to a control (CON) group (n ...

journal_title：American journal of hypertension

authors： Dengel DR,Galecki AT,Hagberg JM,Pratley RE

更新日期：1998-12-01 00:00:00

abstract：:To study the circulating humoral factor modifying transmembrane sodium transport, plasma was obtained from 12 patients with essential hypertension (EH) fed a high sodium diet (NaCl 15 to 17 g/d) for seven days and thereafter a low sodium diet (NaCl 2 to 3 g/d) for seven days. Ouabain-sensitive 86Rb+ influx into the re...

journal_title：American journal of hypertension

authors： Ashida T,Kuramochi M,Kojima S,Yoshimi H,Kawano Y,Kimura G,Abe H,Imanishi M,Yoshida K,Kawamura M

更新日期：1989-07-01 00:00:00

abstract：:Experimental research using in vitro and in vivo models of vascular injury have delineated several common mechanisms that characterize the arterial damage in diseases such as atherosclerosis and hypertension. Changes in endothelial permeability, smooth muscle cell proliferation, and accumulation of connective tissue m...

journal_title：American journal of hypertension

authors： Weinstein DB,Heider JG

更新日期：1989-03-01 00:00:00

abstract：:To clarify the function of polymorphonuclear leukocytes (PMN) in spontaneously hypertensive rats (SHR) and the effect of beraprost sodium (BS) on these functions, we examined superoxide anion (O2-) production and adherent activity by PMN, as well as modification of these functions by BS ex vivo and in vitro. In study ...

journal_title：American journal of hypertension

authors： Ohmori M,Kitoh Y,Kawaguchi A,Harada K,Sugimoto K,Fujimura A

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Seventeen percent of youth in the United States are obese. Obesity has been linked to higher prevalence of hypertension. Past studies were limited by their size and conflicting results. The aim of this study was to analyze trends in adolescents' obesity between 1998 and 2011 and to evaluate the relationship ...

journal_title：American journal of hypertension

authors： Chorin E,Hassidim A,Hartal M,Havakuk O,Flint N,Ziv-Baran T,Arbel Y

更新日期：2015-09-01 00:00:00