Inhibition of oxidative stress and improvement of endothelial function by amlodipine in angiotensin II-infused rats.

abstract：BACKGROUND:Many studies have examined differences in hypertension across race/ethnic groups but few have evaluated differences within groups. METHODS:We investigated within-group geographic variations in hypertension prevalence among 3,322 black and white participants of the Multi-Ethnic Study of Atherosclerosis (MESA...

journal_title：American journal of hypertension

authors： Kershaw KN,Diez Roux AV,Carnethon M,Darwin C,Goff DC Jr,Post W,Schreiner PJ,Watson K

更新日期：2010-01-01 00:00:00

abstract：:Since we and others have found a decrease in intestinal Ca2+ absorption and renal Ca2+ reabsorption in the mature spontaneously hypertensive rat (SHR) at the tissue and cell level, we asked whether the transport defect was located at the luminal or the basolateral side of the epithelial cell. We studied intestinal and...

journal_title：American journal of hypertension

authors： Hennessen U,Chabanis S,Silva SL,Nabarra B,Drüeke T,Lacour B

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:The morbidity and mortality benefits of blood pressure (BP) control for the elderly is well documented. The cognitive consequences of hypertension control in this population, however, are still under debate. We aim to study the association between BP and cognitive performance in the elderly. Specifically, we...

journal_title：American journal of hypertension

authors： Paran E,Anson O,Reuveni H

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Hydrogen sulfide (H2S) is an important endogenous gaseous transmitter in many physiological functions. Plasma H2S decreased, and angiotensin II (Ang II) type 1 receptor (AT1R) increased in the myocardial tissues in 2-kidney 1-clip (2K1C) rats than in normotensive rats. Accumulating evidences suggest that H2S...

journal_title：American journal of hypertension

authors： Liu SY,Duan XC,Jin S,Teng X,Xiao L,Xue HM,Wu YM

更新日期：2017-01-01 00:00:00

abstract：:It has been suggested that hyperinsulinemia compensating insulin resistance in glucose metabolism may be a pathogenic factor in essential hypertension. On the other hand, age-associated increases in the prevalence of glucose intolerance and hypertension are also well established. The aim of this study is to clarify th...

journal_title：American journal of hypertension

authors： Miyazaki Y,Hirata A,Murakami H,Fukuoka M,Agata J,Higashiura K,Masuda A,Ura N,Shimamoto K

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Increased sodium intake has been positively associated with high blood pressure (BP) and hypertensive target organ damage, but associations with cardiac structure in nonhypertensive individuals have yielded inconsistent results. We tested the hypothesis that sodium intake is associated with left ventricular ...

journal_title：American journal of hypertension

authors： Dhingra R,Pencina MJ,Benjamin EJ,Levy D,Larson MG,Meigs JB,Rifai N,D'Agostino RB Sr,Vasan RS

更新日期：2004-10-01 00:00:00

abstract：:Intranasal administration of some peptides has been shown to directly influence central nervous functions, thus pointing to a nose-brain pathway for these substances in humans. The present study investigated whether intranasal administration of angiotensin II (ANG II) affects central nervous functions of cardiovascula...

journal_title：American journal of hypertension

authors： Derad I,Willeke K,Pietrowsky R,Born J,Fehm HL

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:There is evidence that diuretics and beta blockers impair glucose tolerance, whereas calcium channel blockers and angiotensin converting enzyme blockers lack this metabolic effect. We compared the effect of a combination therapy with a nondihydropyridine calcium channel blocker plus an angiotensin converting...

journal_title：American journal of hypertension

authors： Holzgreve H,Nakov R,Beck K,Janka HU

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:We reported that insulin modestly stimulates NAD(P)H oxidase activity in cultured rat vascular smooth muscle cells (VSMC) and synergistically stimulates enzyme activity with angiotensin II (Ang II), leading to synergistic stimulation of VSMC migration. The aim of this study was to determine the mechanism of ...

journal_title：American journal of hypertension

authors： Yang M,Kahn AM

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:The W allele of the G460W polymorphism in the adducin-1 gene has been occasionally associated with increased blood pressure (BP). The aim of this study was to test whether the G460W variant is associated with BP levels and BP progression rate and whether G460W associations with BP are affected by sex, body m...

journal_title：American journal of hypertension

authors： Fava C,Montagnana M,Almgren P,Rosberg L,Guidi GC,Berglund G,Melander O

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Schlager inbred hypertensive mice (BPH/2J) have been suggested to have high blood pressure (BP) due to an overactive sympathetic nervous system (SNS). The brain nuclei associated with the hypertension are also those involved in the integration of the cardiovascular responses to stress. Therefore, in the pres...

journal_title：American journal of hypertension

authors： Davern PJ,Jackson KL,Nguyen-Huu TP,La Greca L,Head GA

更新日期：2010-08-01 00:00:00

abstract：:Body sodium works together with the plasma renin-angiotensin system to ensure adequate blood flow to the tissues. Body sodium content determines the extracellular fluid (ECF) volume ensuring that, with each heart beat, a sufficient volume of fluid is delivered into the arterial space. At the same time the kidneys moni...

journal_title：American journal of hypertension

authors： Laragh JH,Sealey JE

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:We investigated the effects of percutaneous transluminal renal angioplasty on left ventricular (LV) mass, and the impact of LV mass reduction on outcomes. METHODS:A total of 144 hypertensive patients with renal artery stenosis (RAS) (mean age 69 years; 22.2% fibromuscular dysplasia (FMD)) who underwent angi...

journal_title：American journal of hypertension

authors： Iwashima Y,Fukuda T,Horio T,Kusunoki H,Hayashi SI,Kamide K,Kawano Y,Ishimitsu T,Yoshihara F

更新日期：2020-05-21 00:00:00

abstract：BACKGROUND:Different methods of normalizing left ventricular (LV) mass for body size identify generally similar relative risks of adverse cardiovascular outcome but with variable prevalences of LV hypertrophy (H). Preliminary results from a population with high prevalence of obesity suggest that the population attribut...

journal_title：American journal of hypertension

authors： de Simone G,Devereux RB,Maggioni AP,Gorini M,de Divitiis O,Verdecchia P,MAVI (MAssa Ventricolare sinistra nell'Ipertensione) Study Group.

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Carvedilol is known to be an adrenoreceptor blocker and free radical scavenger, used in hypertension and cardiac failure. However, its therapeutic actions cannot be fully explained by these mechanisms. In these studies, we tested the hypothesis that carvedilol action is associated with the synthesis/release ...

journal_title：American journal of hypertension

authors： Afonso RA,Patarrao RS,Macedo MP,Carmo MM

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:There is evidence from genome wide association study that single-nucleotide polymorphisms (SNPs) in the 5' end of the uromodulin gene (UMOD) affect uromodulin excretion and blood pressure (BP). Uromodulin is almost exclusively expressed in the thick ascending limb of the loop of Henle (TAL) and its effect on...

journal_title：American journal of hypertension

authors： McCallum L,Brooksbank K,McConnachie A,Aman A,Lip S,Dawson J,MacIntyre IM,MacDonald TM,Webb DJ,Padmanabhan S

更新日期：2020-10-21 00:00:00

abstract：:Sodium ions markedly decreased in vitro renal alpha 2-adrenoceptor affinity for epinephrine in Sabra hypertensive (SBH) but not in normotensive (SBN) rats. Under these conditions, affinity of alpha 1-adrenoceptor for epinephrine was unchanged in SBH and SBN rats. If these data could be confirmed in vivo, the sodium io...

journal_title：American journal of hypertension

authors： Qing W,Dausse JP,Ben-Ishay D

更新日期：1991-03-01 00:00:00

abstract：:To clarify characteristics of the patients in whom exercise training lowers blood pressure and to elucidate the mechanisms by which exercise training lowers blood pressure, we evaluated 24-h blood pressure, glomerular filtration rate (GFR), renal blood flow (RBF), filtration fraction (FF), plasma renin activity (PRA),...

journal_title：American journal of hypertension

authors： Kohno K,Matsuoka H,Takenaka K,Miyake Y,Nomura G,Imaizumi T

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:It is unknown whether the physiological impact of a given blood pressure (BP) varies by body size. We explored interactions between higher vs. lower systolic BP (SBP) targets and anthropometric measures (body mass index (BMI), body surface area (BSA), height, weight) and recurrent stroke and death in the Sec...

journal_title：American journal of hypertension

authors： Field TS,McClure LA,White CL,Pergola PE,Hart RG,Benavente OR,Hill MD,SPS3 Investigators.

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Hypertension has recently been identified as the leading risk factor for global mortality. This study aims to present the national prevalence of hypertension and prehypertension and, their determinants in Vietnamese adults. METHODS:Nationally representative data were obtained from the National Adult Overwei...

journal_title：American journal of hypertension

authors： Do HT,Geleijnse JM,Le MB,Kok FJ,Feskens EJ

更新日期：2015-01-01 00:00:00

abstract：:Alterations in Na, K ATPase pump activity as well as erythrocyte (RBC) intracellular sodium concentration (Nai) have been demonstrated in humans and rats with established hypertension. The contribution of hypertension itself to these changes is unclear. Accordingly, we investigated RBC ion transport and plasma ouabain...

journal_title：American journal of hypertension

authors： McCormick CP,Hennessy JF,Rauch AL,Buckalew VM Jr

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Evaluating effect of acute or chronic use of antihypertensives on risk of falls in older adults. METHODS:Data sources: Systematic search of primary research articles in CINAHL, Cochrane, EBM, EMBASE, and MEDLINE databases from January 1 2007 to June 1 2017. Study selection: Research studies of cohort, case-...

journal_title：American journal of hypertension

authors： Kahlaee HR,Latt MD,Schneider CR

更新日期：2018-03-10 00:00:00

abstract：:Hypertension is a common finding among obstructive sleep apnea (OSA) patients, and is thought to be caused by sympathetic hyperactivity. The present study compares the contributions of the respiratory disturbance index (RDI) as a reflection of sleep fragmentation, and the magnitude of oxygen desaturation, to sympathet...

journal_title：American journal of hypertension

authors： Peled N,Greenberg A,Pillar G,Zinder O,Levi N,Lavie P

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Endothelial dysfunction and arterial stiffening are commonly observed in type 2 diabetes. These abnormalities might be secondary to increased plasma concentrations of homocysteine. We sought to determine whether oral folic acid supplementation, by lowering homocysteine levels, enhanced endothelial function a...

journal_title：American journal of hypertension

authors： Mangoni AA,Sherwood RA,Asonganyi B,Swift CG,Thomas S,Jackson SH

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Aldosterone acts to restrain the extracellular potassium (K+) concentration. Blacks have on average lower plasma aldosterone concentrations (PACs) than Whites. Whether this ethnic difference is associated with similar changes in the concentration of K+ is unclear. METHODS:Subjects were Blacks and Whites fro...

journal_title：American journal of hypertension

authors： Tu W,Eckert GJ,Decker BS,Howard Pratt J

更新日期：2017-05-01 00:00:00

abstract：:Blood pressure and heart period variability have been measured directly in 142 subjects with mild hypertension over 24 h. The variabilities have been expressed as the standard deviation of 2 min averages of all beats over 24 h. Baroreflex sensitivity was assessed in 102 subjects by the phenylephrine method. Blood pres...

journal_title：American journal of hypertension

authors： Coats AJ,Conway J,Sleight P,Meyer TE,Somers VK,Floras JS,Vann Jones J

更新日期：1991-03-01 00:00:00

abstract：:Stroke-prone spontaneously hypertensive rats (SHRSP), subjected to high NaCl, show severe hypertension, organ damage, and early death. Preventive treatment with angiotensin II type 1 (AT1) receptor antagonists is known to be effective. Previously, we found that angiotensin converting enzyme (ACE) inhibition could redu...

journal_title：American journal of hypertension

authors： Blezer EL,Nicolay K,Koomans HA,Joles JA

更新日期：2001-01-01 00:00:00

abstract：:Stroke (brain attack) is currently the third leading cause of death in Western societies. Recent advances in molecular genetics have finally demonstrated what has long been suggested by the clinical observation, that is, stroke is not only the complication of major pathologic conditions such as atherosclerosis, hypert...

journal_title：American journal of hypertension

authors： Rubattu S,Giliberti R,Volpe M

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:The association between hypertension (HTN) and inflammatory biomarkers (interleukin-6 [IL-6] and high-sensitivity C-reactive protein [hsCRP]) in HIV-positive persons with CD4+ count >500 cells/mm3 is unknown. METHODS:We studied HTN in participants of the Strategic Timing of AntiRetroviral Treatment (START) ...

journal_title：American journal of hypertension

authors： Ghazi L,Baker JV,Sharma S,Jain MK,Palfreeman A,Necsoi C,Murray DD,Neaton JD,Drawz PE

更新日期：2020-01-01 00:00:00

abstract：:The renin-angiotensin-aldosterone system plays a major role in the pathogenesis of hypertension by enhancing the production or the activity of angiotensin II (ANG II). We evaluated the effects of hormone replacement therapy (HRT) on the renin-angiotensin-aldosterone system and on bradykinin in postmenopausal women (PM...

journal_title：American journal of hypertension

authors： Umeda M,Ichikawa S,Kanda T,Sumino H,Kobayashi I

更新日期：2001-03-01 00:00:00