Blood pressure in people in Greenland assessed by measuring renovasculopathies of hypertension at autopsy.

abstract：BACKGROUND:Uncontrolled treatment-resistant hypertension (TRH), i.e., blood pressure (BP, mm Hg) ≥140/≥90mm Hg in and out of office on ≥3 different BP medications at optimal doses, is common and has a poor prognosis. Aldosterone antagonist (AA) and renin-guided therapy (RGT) are effective strategies for improving BP co...

journal_title：American journal of hypertension

authors： Egan BM,Laken MA,Sutherland SE,Qanungo S,Fleming DO,Cook AG,Hester WH,Jones KW,Jebaily GC,Valainis GT,Way CF,Wright MB,Davis RA

更新日期：2016-08-01 00:00:00

abstract：:Reversible posterior leukoencephalopathy syndrome (RPLS) is an uncommon entity related to multiple and different pathologies, the most common being hypertensive crisis. It is believed to be secondary to the breakdown on the blood-brain barrier. At the beginning, it is undistinguishable from other leukoencephalopathies...

journal_title：American journal of hypertension

authors： Giner V,Fernández C,Esteban MJ,Galindo MJ,Forner MJ,Guix J,Redón J

更新日期：2002-05-01 00:00:00

abstract：:During the course of a long-term, prospective, randomized study in 77 hypertensive nephrosclerosis patients, five patients developed evidence suggestive of renal artery stenosis. However, arteriography demonstrated patent renal arteries. The evidence suggestive of renal artery stenosis was: (1) converting-enzyme inhib...

journal_title：American journal of hypertension

authors： Pettinger WA,Mitchell HC,Lee HC,Redman HC

更新日期：1989-05-01 00:00:00

abstract：:The results of our previous studies suggested that endothelin-1 (ET-1) might be contributory to the impaired uteroplacental blood flow seen in preeclampsia. The aim of this study was to investigate the in vitro influence of isradipine on ET-1-induced contraction of myometrial resistance arteries from pregnant women, a...

journal_title：American journal of hypertension

authors： Kublickiene KR,Wolff K,Kublickas M,Lindblom B,Lunell NO,Nisell H

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Despite readily available treatments, control of blood pressure (BP) with population aging remains suboptimal. Further, there are gaps in the understanding of the management of high BP in the aged. We explored antihypertensive treatment and control among elderly hypertensive participants free from overt card...

journal_title：American journal of hypertension

authors： Chowdhury EK,Nelson MR,Ernst ME,Margolis KL,Beilin LJ,Johnston CI,Woods RL,Murray AM,Wolfe R,Storey E,Shah RC,Lockery JE,Tonkin AM,Newman AB,Williamson JD,Abhayaratna WP,Stocks NP,Fitzgerald SM,Orchard SG,Trevaks RE

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Chronic systemic inflammation has been implicated in the pathogenesis of hypertension and cardiovascular disease. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by chronic inflammation and an increased risk for cardiovascular disease. Currently few studies have evaluated the potent...

journal_title：American journal of hypertension

authors： Barnes JN,Nualnim N,Sugawara J,Sommerlad SM,Renzi CP,Tanaka H

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Circulating blood levels of human urotensin II (U-II), the most potent vasoconstrictor peptide identified to date, are increased in patients with essential hypertension. Our previous studies showed that U-II accelerates human macrophage foam cell formation and vascular smooth muscle cell proliferation, sugge...

journal_title：American journal of hypertension

authors： Suguro T,Watanabe T,Ban Y,Kodate S,Misaki A,Hirano T,Miyazaki A,Adachi M

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Although insulin resistance (IR) is thought to be related to vascular dysfunction, the difference in the relationship of IR to microvasculature and macrovasculature reactivity has not yet been clarified. The present study was conducted to clarify whether the IR is more closely related to the macrovasculature...

journal_title：American journal of hypertension

authors： Yoshida M,Tomiyama H,Yamada J,Matsumoto C,Odaira M,Shiina K,Yamashina A

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:We reported that insulin modestly stimulates NAD(P)H oxidase activity in cultured rat vascular smooth muscle cells (VSMC) and synergistically stimulates enzyme activity with angiotensin II (Ang II), leading to synergistic stimulation of VSMC migration. The aim of this study was to determine the mechanism of ...

journal_title：American journal of hypertension

authors： Yang M,Kahn AM

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Hydrogen sulfide (H2S) is an important endogenous gaseous transmitter in many physiological functions. Plasma H2S decreased, and angiotensin II (Ang II) type 1 receptor (AT1R) increased in the myocardial tissues in 2-kidney 1-clip (2K1C) rats than in normotensive rats. Accumulating evidences suggest that H2S...

journal_title：American journal of hypertension

authors： Liu SY,Duan XC,Jin S,Teng X,Xiao L,Xue HM,Wu YM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Nifedipine has been reported to cause impairment of insulin sensitivity. But recently a controlled-released formulation of nifedipine (nifedipine-GITS) has been reported that it could improve insulin sensitivity. METHODS:We evaluated insulin sensitivity in two groups of essential hypertensive subjects befor...

journal_title：American journal of hypertension

authors： Koyama Y,Kodama K,Suzuki M,Harano Y

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:The risk for cardiovascular events increases within hours of near-roadway exposures. We aimed to determine the traffic-related air pollution (TRAP) and biological mechanisms involved and if reducing particulate matter <2.5 µm (PM2.5) inhalation is protective. METHODS:Fifty healthy-adults underwent multiple ...

journal_title：American journal of hypertension

authors： Morishita M,Wang L,Speth K,Zhou N,Bard RL,Li F,Brook JR,Rajagopalan S,Brook RD

更新日期：2019-10-16 00:00:00

abstract：BACKGROUND:Obesity has been described as a predictor of cardiovascular mortality, and some studies have reported an association with obesity and increased aortic stiffness. Other studies have not identified obesity to be an independent risk factor. Therefore, the purpose of our study was to determine the association be...

journal_title：American journal of hypertension

authors： Rodrigues SL,Baldo MP,Lani L,Nogueira L,Mill JG,Sa Cunha Rd

更新日期：2012-10-01 00:00:00

abstract：:Insulin acutely inhibits contraction of primary cultured vascular smooth muscle (VSM) cells from canine femoral artery by inhibiting contractile agonist-induced Ca2+ influx. Insulin also inhibits contraction at step(s) distal to intracellular Ca2+ concentration (Ca2+i) by stimulating cyclic guanosine monophosphate (GM...

journal_title：American journal of hypertension

authors： Kahn AM,Allen JC,Seidel CL,Song T

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:New onset resistant hypertension in a previously stable patient with chronic hypertension should lead to consideration of secondary causes. Electrolyte abnormalities are useful clues for identifying some common causes, especially mineralocorticoid excess. CASE PRESENTATION:We report the case of a 69-year-ol...

journal_title：American journal of hypertension

authors： Klomjit N,Rowan DJ,Kattah AG,Bancos I,Taler SJ

更新日期：2019-11-15 00:00:00

abstract：BACKGROUND:Previous autopsy studies suggested that a reduced nephron number is associated with increased risk of hypertension and chronic kidney disease. However, the significance of the nephron number estimated from a renal biopsy in patients with hypertensive nephrosclerosis (HNS) has not yet been elucidated. METHOD...

journal_title：American journal of hypertension

authors： Haruhara K,Tsuboi N,Kanzaki G,Koike K,Suyama M,Shimizu A,Miyazaki Y,Kawamura T,Ogura M,Yokoo T

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Insulin inhibits contraction and migration of primary confluent, cultured canine vascular smooth muscle cells (VSMCs) with inducible nitric oxide synthase (iNOS) by stimulating cyclic GMP (cGMP) production. The present study was performed to determine how insulin stimulates guanylate cyclase activity in thes...

journal_title：American journal of hypertension

authors： Kahn AM,Allen JC,Zhang S

更新日期：2002-03-01 00:00:00

abstract：:We studied how closely changes in electronically monitored physical activity are reflected in changes in blood pressure and heart rate in a group of untreated hypertensive subjects. Thirty-nine hypertensive patients (office blood pressure > 140/ 90 mm Hg) of mean age 57 +/- 10 years (mean +/-SD) wore an ambulatory blo...

journal_title：American journal of hypertension

authors： Mansoor GA,White WB,McCabe EJ,Giacco S

更新日期：2000-03-01 00:00:00

abstract：:To evaluate the clinical importance of serum hepatocyte growth factor (HGF) concentration, we designed two clinical investigations. The first study analyzed the correlation between serum HGF concentration and clinical arterial stiffness or the vasodilator response to reactive hyperemia in hypertensive patients. The se...

journal_title：American journal of hypertension

authors： Komai N,Ohishi M,Morishita R,Moriguchi A,Kaibe M,Matsumoto K,Rakugi H,Higaki J,Ogihara T

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Carotid-femoral pulse-wave velocity (PWV) provides a comprehensive noninvasive indication of arterial stiffness, and is now established as a strong marker of cardiovascular disease (CVD). The correlation between peripheral blood pressure (BP) and PWV and their respective influences on mortality have been poo...

journal_title：American journal of hypertension

authors： Miljkovic D,Perret-Guillaume C,Alla F,Salvi P,Erpelding ML,Benetos A

更新日期：2013-02-01 00:00:00

abstract：:A prospective randomized, double-blind, double-dummy study investigated the effects of two angiotensin converting enzyme (ACE) inhibitors on urinary albumin excretion in nondiabetic patients with mild to moderate essential hypertension. At the end of a 4-week placebo run-in period, 36 patients were randomly allocated ...

journal_title：American journal of hypertension

authors： Puig JG,Mateos FA,Ramos TH,Lavilla MP,Capitán MC,Gil A

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:We evaluated the relationship of the severity of hyperuricemia and the flow-mediated vasodilatation of the brachial artery (FMD) in patients with and without the metabolic syndrome (MetS). METHODS:In a cross-sectional study, FMD was obtained in 2,732 Japanese healthy men (49 ± 8 years) who had no cardiovasc...

journal_title：American journal of hypertension

authors： Tomiyama H,Higashi Y,Takase B,Node K,Sata M,Inoue T,Ishibashi Y,Ueda S,Shimada K,Yamashina A

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Elastin microfibril interfacer 1 (EMILIN-1) is a negative regulator of the transforming growth factor-beta (TGF-beta) signaling, which is involved in blood pressure (BP) homeostasis. Emilin1 knockout mice display elevated BP. The aim of the present study was to assess the association between the human EMILIN...

journal_title：American journal of hypertension

authors： Shimodaira M,Nakayama T,Sato N,Naganuma T,Yamaguchi M,Aoi N,Sato M,Izumi Y,Soma M,Matsumoto K

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:We determined the prognostic value of the Cornell/strain [C/S] index, a simple electrocardiographic (ECG) index for left ventricular hypertrophy (LVH) defined by the presence of either a classic strain pattern or a Cornell voltage (sum of R in aVL + S in V(3)) >2.0 mV in women or 2.4 mV in men, or both. MET...

journal_title：American journal of hypertension

authors： Verdecchia P,Angeli F,Reboldi G,Carluccio E,Benemio G,Gattobigio R,Borgioni C,Bentivoglio M,Porcellati C,Ambrosio G

更新日期：2003-08-01 00:00:00

abstract：:The relations between left ventricular mass (LVM), peripheral resistance artery structure, and ambulatory BP were studied in 83 patients with previously untreated or poorly regulated essential hypertension and 20 healthy controls of similar age and sex. LVM was assessed by echocardiography. Signs of left ventricular h...

journal_title：American journal of hypertension

authors： Sihm I,Schroeder AP,Aalkjaer C,Holm M,Mørn B,Mulvany M,Thygesen K,Lederballe O

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Carvedilol is known to be an adrenoreceptor blocker and free radical scavenger, used in hypertension and cardiac failure. However, its therapeutic actions cannot be fully explained by these mechanisms. In these studies, we tested the hypothesis that carvedilol action is associated with the synthesis/release ...

journal_title：American journal of hypertension

authors： Afonso RA,Patarrao RS,Macedo MP,Carmo MM

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:We examined the associations of epithelial sodium channel (ENaC) genes with blood pressure (BP) changes and hypertension incidence in a longitudinal family study. METHODS:A total of 2,755 Han Chinese participants of the Genetic Epidemiology Network of Salt Sensitivity (GenSalt) baseline examination were eli...

journal_title：American journal of hypertension

authors： Yang X,He J,Gu D,Hixson JE,Huang J,Rao DC,Shimmin LC,Chen J,Rice TK,Li J,Schwander K,Kelly TN

更新日期：2014-11-01 00:00:00

abstract：:Most ambulatory blood pressure monitoring (ABPM) studies have used a mechanical clock as the reference time, but there is no biologic background for assuming that midnight by the mechanical clock is zero hour by the biologic clock. The aim of this study was to determine the biologic zero hour as the zero reference tim...

journal_title：American journal of hypertension

authors： Okutani M,Komori S,Iwasaki H,Mochizuki Y,Kohno I,Mochizuki S,Ishii H,Ijiri H,Tamura K

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Our aim was to assess whether home blood pressure (HBP) and ambulatory BP monitoring measurement (ABPM), in addition to office BP (OBP) predict changes of cardiovascular biomarkers during antihypertensive treatment. METHODS:Two hundred and fifty-two hypertensive patients (mean age, 68 years; men: 41%) under...

journal_title：American journal of hypertension

authors： Yano Y,Hoshide S,Shimizu M,Eguchi K,Ishikawa J,Ishikawa S,Shimada K,Kario K

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:We compare patterns of blood pressure (BP) and prevalence of hypertension between white-Dutch and their South-Asian and African minority groups with their corresponding white-English and their South-Asian and African ethnic minority groups; and the contribution of physical activity, body sizes, and socioecon...

journal_title：American journal of hypertension

authors： Agyemang C,Kunst A,Bhopal R,Zaninotto P,Unwin N,Nazroo J,Nicolaou M,Redekop WK,Stronks K

更新日期：2010-06-01 00:00:00