Adipose tissue-specific regulation of angiotensinogen in obese humans and mice: impact of nutritional status and adipocyte hypertrophy.

abstract：:Alterations in Na, K ATPase pump activity as well as erythrocyte (RBC) intracellular sodium concentration (Nai) have been demonstrated in humans and rats with established hypertension. The contribution of hypertension itself to these changes is unclear. Accordingly, we investigated RBC ion transport and plasma ouabain...

journal_title：American journal of hypertension

authors： McCormick CP,Hennessy JF,Rauch AL,Buckalew VM Jr

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:The renin-angiotensin system (RAS) plays a major role in promoting left ventricular (LV) remodeling in essential hypertension. We designed a controlled, randomized pilot study aimed to test the hypothesis that the dual RAS blockade with angiotensin-converting enzyme (ACE) inhibitor (ACEi) + angiotensin II re...

journal_title：American journal of hypertension

authors： Grandi AM,Solbiati F,Laurita E,Maresca AM,Nicolini E,Marchesi C,Gianni M,Guasti L,Venco A

更新日期：2008-02-01 00:00:00

abstract：:The effects of activators and inhibitors of protein kinase C (PKC) on the production of C-type natriuretic peptide (CNP) by cultured human aortic endothelial cells were examined. The PKC activators phorbol 12-myristate 13-acetate (PMA) and 1-oleoyl 2-acetyl glycerol (OAG) stimulated CNP release; the maximal effects we...

journal_title：American journal of hypertension

authors： Yamada Y,Yokota M

更新日期：1996-09-01 00:00:00

abstract：:Atherosclerosis is increasingly recognized as an inflammatory vascular disease, and high blood pressure (BP) has been suggested to exert a proinflammatory action. Whether plasma viscosity (PV), a major determinant of blood flow in microcirculation and a marker of systemic inflammation and cardiovascular risk, is incre...

journal_title：American journal of hypertension

authors： Ciuffetti G,Schillaci G,Lombardini R,Pirro M,Vaudo G,Mannarino E

更新日期：2005-07-01 00:00:00

abstract：:Cultured vascular smooth muscle cells (VSMCs) of the spontaneously hypertensive rat (SHR) show a higher density (Bmax) of ANP receptors and a blunted cyclic (c) GMP response to the hormone. To explore the idea that a higher cytosolic free Ca2+ (Cai2+) may be responsible for a blunted cGMP response to ANP, we examined ...

journal_title：American journal of hypertension

authors： Nakamura M,Nakamura A,Hatori N,Fine BP,Aviv A

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Obesity has been described as a predictor of cardiovascular mortality, and some studies have reported an association with obesity and increased aortic stiffness. Other studies have not identified obesity to be an independent risk factor. Therefore, the purpose of our study was to determine the association be...

journal_title：American journal of hypertension

authors： Rodrigues SL,Baldo MP,Lani L,Nogueira L,Mill JG,Sa Cunha Rd

更新日期：2012-10-01 00:00:00

abstract：:The purpose of this study was to examine the variability of 24-hour urinary and serum creatinine levels and creatinine clearance in normal subjects and to develop nomograms for assessing the adequacy of 24-hour urine collections. The data were from a longitudinal research program examining biochemical, hormonal, and h...

journal_title：American journal of hypertension

authors： James GD,Sealey JE,Alderman M,Ljungman S,Mueller FB,Pecker MS,Laragh JH

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:It is not known whether strict control of blood pressure (BP) in mild post-transplant hypertension gives any benefit. Our primary objective was to test the antihypertensive effects of lisinopril added to standard therapy on ambulatory BP (ABP) of post-transplant patients. The secondary objective was to monit...

journal_title：American journal of hypertension

authors： Opie LH,Haus M,Commerford PJ,Levetan B,Moore K,Brink J

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:We compare patterns of blood pressure (BP) and prevalence of hypertension between white-Dutch and their South-Asian and African minority groups with their corresponding white-English and their South-Asian and African ethnic minority groups; and the contribution of physical activity, body sizes, and socioecon...

journal_title：American journal of hypertension

authors： Agyemang C,Kunst A,Bhopal R,Zaninotto P,Unwin N,Nazroo J,Nicolaou M,Redekop WK,Stronks K

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Normal pregnancy is characterized by a decrease in peripheral resistance and generalized vasodilation resulting in plasma volume expansion, which is associated with intrauterine growth. Stiffness of the arterial system may be a measure of the degree of plasma volume expansion. Pulse wave velocity (PWV), meas...

journal_title：American journal of hypertension

authors： Elvan-Taspinar A,Franx A,Bots ML,Koomans HA,Bruinse HW

更新日期：2005-03-01 00:00:00

abstract：:Conflicting reports exist as to whether air traffic controllers (ATC) have an increase in blood pressure (BP) and prevalence of hypertension because of the stressful nature of their job. We have addressed the issue in male ATC working at the Linate airport of Milan. A total of 80 ATC participated, and the 24 h blood p...

journal_title：American journal of hypertension

authors： Sega R,Cesana G,Costa G,Ferrario M,Bombelli M,Mancia G

更新日期：1998-02-01 00:00:00

abstract：:Since we and others have found a decrease in intestinal Ca2+ absorption and renal Ca2+ reabsorption in the mature spontaneously hypertensive rat (SHR) at the tissue and cell level, we asked whether the transport defect was located at the luminal or the basolateral side of the epithelial cell. We studied intestinal and...

journal_title：American journal of hypertension

authors： Hennessen U,Chabanis S,Silva SL,Nabarra B,Drüeke T,Lacour B

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:The role of pulsatile hemodynamics in the management of patients with acute heart failure syndrome (AHFS) remains to be elucidated. We investigated the changes of the pulsatile hemodynamics along the hospital course of AHFS in relation to short-term outcomes. METHODS:A total of 80 AHFS patients (73.2 ± 14.1...

journal_title：American journal of hypertension

authors： Sung SH,Yu WC,Cheng HM,Chuang SY,Wang KL,Huang CM,Chen CH

更新日期：2011-07-01 00:00:00

abstract：:The present study was designed to investigate the role of the autonomic nervous system in experimental hypertension induced by chronic administration of N-nitro-L-arginine methyl ester (L-NAME) in the drinking water (1 mg/mL) over 6 days. L-NAME ingestion caused a large rise in resting mean arterial pressure (MAP) (17...

journal_title：American journal of hypertension

authors： Cunha RS,Cabral AM,Vasquez EC

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Elevated blood pressure (BP) is a risk factor for cardiovascular disease (CVD), but it remains unclear which component-alone or in combination-is the best predictor. We sought to determine which BP parameters are important predictors of CVD death across a wide age range. METHODS:We used a prospective cohort...

journal_title：American journal of hypertension

authors： Bowman TS,Sesso HD,Gaziano JM

更新日期：2006-01-01 00:00:00

abstract：:We investigated the effects of 17 beta-estradiol (beta E2), alpha-estradiol (alpha E2), and progesterone (P) on baseline and vasopressin (AVP)-induced [Ca2+]i in human platelets obtained from healthy male and female volunteers. Platelets were treated with beta E2, alpha E2, P, or ethanol vehicle for 30 min at 37 degre...

journal_title：American journal of hypertension

authors： Raman BB,Standley PR,Rajkumar V,Ram JL,Sowers JR

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:The expression of Na(+)-K(+)-2Cl(-) cotransporter 1 (NKCC1) is upregulated in spontaneously hypertensive rat (SHR). We investigated whether expression of NKCC1 is epigenetically regulated during postnatal development of hypertension. METHODS:The mesenteric arteries from 5-, 10-, and 18-week-old Wistar-Kyoto...

journal_title：American journal of hypertension

authors： Cho HM,Lee HA,Kim HY,Han HS,Kim IK

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Many patients prefer herbal medications to conventional drugs. Limited trial evidence suggests that garlic preparations reduce high blood pressure (BP). METHODS:We searched electronic databases through March 2014 to identify all randomized controlled trials that compared a garlic preparation to placebo in h...

journal_title：American journal of hypertension

authors： Rohner A,Ried K,Sobenin IA,Bucher HC,Nordmann AJ

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Although the acute increase of arterial stiffness and blood pressure (BP) after cigarette smoking in healthy smokers is considered a possible mechanism of increased cardiovascular risk, the acute effect of smoking on arterial stiffness in hypertensive smokers is unknown. We investigated the acute effects of ...

journal_title：American journal of hypertension

authors： Rhee MY,Na SH,Kim YK,Lee MM,Kim HY

更新日期：2007-06-01 00:00:00

abstract：:In this study, 395 healthy children had blood pressure and heart rate measured both at rest and during a stressful video game. Identical measurement procedures were used for three annual examinations. Consistently, black children demonstrated significantly greater pressor responses than white children. In view of the ...

journal_title：American journal of hypertension

authors： Murphy JK,Alpert BS,Walker SS

更新日期：1991-07-01 00:00:00

abstract：:Blood pressure and heart period variability have been measured directly in 142 subjects with mild hypertension over 24 h. The variabilities have been expressed as the standard deviation of 2 min averages of all beats over 24 h. Baroreflex sensitivity was assessed in 102 subjects by the phenylephrine method. Blood pres...

journal_title：American journal of hypertension

authors： Coats AJ,Conway J,Sleight P,Meyer TE,Somers VK,Floras JS,Vann Jones J

更新日期：1991-03-01 00:00:00

abstract：:Insulin resistance and hypertension, as well as dyslipidemia, frequently cooccur. Evidence that nitric oxide (NO) plays a crucial role in the long-term regulation of systolic blood pressure led us to examine whether enhanced vasoconstriction and hypertension induced by NO synthase inhibitor could lead to insulin and l...

journal_title：American journal of hypertension

authors： Erlich Y,Rosenthal T

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Hypertension is the leading global preventable risk factor for premature death. While hypertension prevalence has been declining in high-income countries, it has increased continuously in low- and middle-income countries. METHODS:We conducted a cross-sectional survey in 7,524 women and men aged 35-74 years ...

journal_title：American journal of hypertension

authors： Rubinstein AL,Irazola VE,Calandrelli M,Chen CS,Gutierrez L,Lanas F,Manfredi JA,Mores N,Poggio R,Ponzo J,Seron P,Bazzano LA,He J

更新日期：2016-12-01 00:00:00

abstract：:This study was undertaken to characterize blood pressure (by continuous blood pressure recording), renal hemodynamics, and excretory function in high-fructose-fed insulin-resistant dogs. We fed 10 mongrel dogs for 28 days with a normal sodium diet containing 60% of the calories either as fructose (n = 6) or dextrose (...

journal_title：American journal of hypertension

authors： Pamies-Andreu E,Fiksen-Olsen M,Rizza RA,Romero JC

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Ascending aortic fractional pulse pressure and fractional systolic pressure (FSP) were demonstrated to differentiate patients with and without coronary artery disease. However, no study so far has analyzed the relationship between FSP and fractional diastolic pressure (FDP) and the extent of coronary artery ...

journal_title：American journal of hypertension

authors： Jankowski P,Kawecka-Jaszcz K,Bryniarski L,Czarnecka D,Brzozowska-Kiszka M,Pośnik-Urbańska A,Kopeć G,Dragan J,Klecha A,Dudek D

更新日期：2004-08-01 00:00:00

abstract：:The "totality" of hypertension clinical trial endpoint data has shown that the absolute benefit of pharmacological blood pressure (BP) lowering is directly related to the BP level and baseline cardiovascular risk, albeit with attenuation of the relative risk reduction per unit of BP lowering in patients with diabetes ...

journal_title：American journal of hypertension

authors： Flack JM,Nolasco C,Levy P

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Blood pressure (BP) measured in the office setting increases from early through later adulthood. However, it is unknown to what extent out-of-office BP derived via ambulatory BP monitoring (ABPM) increases over time, and which participant characteristics and risk factors might contribute to these increases. ...

journal_title：American journal of hypertension

authors： Bundy JD,Jaeger BC,Huffman MD,Knox SS,Thomas SJ,Shimbo D,Booth Iii JN,Lewis CE,Edwards LJ,Schwartz JE,Muntner P

更新日期：2020-11-17 00:00:00

abstract：:The regulation of atrial natriuretic peptide (ANP) synthesis within cardiac atrial myocytes was investigated in 8 patients undergoing cardiac surgery (valve replacement or coronary bypass graft). Hemodynamic data were obtained during cardiac catheterization and venous plasma samples for ANP were withdrawn prior to sur...

journal_title：American journal of hypertension

authors： Haass M,Fischer TA,Hänze J,Saggau W,Lang RE,Dietz R

更新日期：1990-03-01 00:00:00

abstract：:Plasma plasminogen activator inhibitor type 1 (PAI-1) and tissue plasminogen activator (tPA) antigens and activities were measured in 28 patients with hypertension and 12 normal controls. Steady state plasma glucose (SSPG) concentrations were also determined after an infusion of somatostatin, insulin and glucose. Pati...

journal_title：American journal of hypertension

authors： Jeng JR,Sheu WH,Jeng CY,Huang SH,Shieh SM

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:We examined data from a cohort of Caucasian women for evidence of an association between serum vitamin D (25-hydroxyvitamin D (25(OH)D)) insufficiency and greater risk of systolic hypertension in the population-based longitudinal Michigan Bone Health and Metabolism Study (MBHMS). METHODS:The cohort includes...

journal_title：American journal of hypertension

authors： Griffin FC,Gadegbeku CA,Sowers MR

更新日期：2011-03-01 00:00:00