Fractional diastolic and systolic pressure in the ascending aorta are related to the extent of coronary artery disease.

abstract：:This study examined the role of the lipoxygenase (LO) pathway in the maintenance of hypertension in rats with two-kidney, one clip (2K,1C) Goldblatt hypertension. A single dose of the lipoxygenase blocker phenidone was injected intraperitoneally to 2K,1C rats during the early phase (14 days) of the development of hype...

journal_title：American journal of hypertension

authors： Nozawa K,Tuck ML,Golub M,Eggena P,Nadler J,Stern N

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) and left ventricular (LV) hypertrophy are considered to be closely associated. However, the relationship has not yet been fully demonstrated and is hence still controversial. The purpose of this study was to assess in hypertensive male patients the relationship between OSA and c...

journal_title：American journal of hypertension

authors： Yamaguchi T,Takata Y,Usui Y,Asanuma R,Nishihata Y,Kato K,Shiina K,Yamashina A

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Although the renin-angiotensin system and insulin resistance (IR) have been identified as major regulators of plasminogen activator inhibitor type-1 (PAI-1), their roles in hypertensive subjects is not clearly defined. METHODS:We examined the effect of dietary salt restriction on PAI-1 levels in 239 hyperte...

journal_title：American journal of hypertension

authors： Srikumar N,Brown NJ,Hopkins PN,Jeunemaitre X,Hunt SC,Vaughan DE,Williams GH

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Sleep apnea is being studied as a risk factor for hypertension. This observational chart review was conducted to determine the long-term effects of continuous positive airway pressure (CPAP) treatment on blood pressure (BP) in a sample of sleep apnea patients from urban and rural populations. METHODS:This s...

journal_title：American journal of hypertension

authors： Dhillon S,Chung SA,Fargher T,Huterer N,Shapiro CM

更新日期：2005-05-01 00:00:00

abstract：:The sensitivity and specificity of screening and diagnostic studies for renovascular hypertension has been the focus of debate and disappointment for many years. The use of these studies has been further restricted by the insistence of clinicians that studies provide visual identification of the anatomy of the renal v...

journal_title：American journal of hypertension

authors： Vidt DG

更新日期：1991-12-01 00:00:00

abstract：:Cocaine causes acute hypertension by blocking catecholamine reuptake. There is evidence that it also impairs the peripheral endothelial nitric oxide system, which is normally vasodilatory. We further explored the role of nitric oxide in cocaine-induced vasoconstriction in anesthetized rats, and in vitro by using isola...

journal_title：American journal of hypertension

authors： Mo W,Singh AK,Arruda JA,Dunea G

更新日期：1998-06-01 00:00:00

abstract：:Mesangial cells in the glomerulus have several important physiological functions, as has been demonstrated by past research. Platelet derived growth factor, thrombin, endothelin, and angiotensin II have all been shown to affect mesangial cell growth and protein synthesis. First generation Ca channel blockers also have...

journal_title：American journal of hypertension

authors： Shultz PJ,Raij L

更新日期：1992-12-01 00:00:00

abstract：:The polymorphism of the angiotensin-converting enzyme gene is considered to be associated with increased risk for stroke, but there is a diversity in the results obtained. The genetic involvement of the renin-angiotensin system in stroke also remains unclear. To predict the genetic risk of lacunar infarction, we condu...

journal_title：American journal of hypertension

authors： Takami S,Imai Y,Katsuya T,Ohkubo T,Tsuji I,Nagai K,Satoh H,Hisamichi S,Higaki J,Ogihara T

更新日期：2000-02-01 00:00:00

abstract：:In this study, 395 healthy children had blood pressure and heart rate measured both at rest and during a stressful video game. Identical measurement procedures were used for three annual examinations. Consistently, black children demonstrated significantly greater pressor responses than white children. In view of the ...

journal_title：American journal of hypertension

authors： Murphy JK,Alpert BS,Walker SS

更新日期：1991-07-01 00:00:00

abstract：:Alteration of calcium metabolism and changes in the levels of calcium-regulating hormones have been described in essential hypertension. In the majority of the reported clinical trials, calcium supplementation has resulted in a decrease in blood pressure. However, the mechanisms by which such a response would be media...

journal_title：American journal of hypertension

authors： Wimalawansa SJ

更新日期：1993-12-01 00:00:00

abstract：:Antihypertensive monotherapy, although commonly used, does not address the multifactorial nature of hypertension as a disease with many pathways. Using more than one drug makes more therapeutic sense because combination agents cover more than one pathway, yet the use of drugs in tandem is typically relegated to more p...

journal_title：American journal of hypertension

authors： Neutel JM

更新日期：1999-08-01 00:00:00

abstract：:The goal of this study was to investigate the activity of the Na+/H+ exchanger in erythrocytes of patients with essential hypertension and its relation with urinary Na+ excretion. The study was performed in cells from 27 untreated hypertensive patients and 30 normotensive controls with similar age and sex distribution...

journal_title：American journal of hypertension

authors： Díez J,Alonso A,Garciandía A,López R,Gómez-Alamillo C,Arrázola A,Fortuño A

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:The aim of our study was to investigate the control of hypertension (HT) in treated children using ambulatory blood pressure (BP) monitoring (ABPM). METHODS:We retrospectively reviewed all ABPM studies in our center. Controlled HT was defined as systolic and diastolic BP index (patients' BP divided by the 9...

journal_title：American journal of hypertension

authors： Seeman T,Dostálek L,Gilík J

更新日期：2012-03-01 00:00:00

abstract：:We investigated the effects of 17 beta-estradiol (beta E2), alpha-estradiol (alpha E2), and progesterone (P) on baseline and vasopressin (AVP)-induced [Ca2+]i in human platelets obtained from healthy male and female volunteers. Platelets were treated with beta E2, alpha E2, P, or ethanol vehicle for 30 min at 37 degre...

journal_title：American journal of hypertension

authors： Raman BB,Standley PR,Rajkumar V,Ram JL,Sowers JR

更新日期：1995-02-01 00:00:00

abstract：:There are a variety of radiopharmaceuticals that can be used to perform captopril renography effectively. We examined a number of technetium and iodine compounds and the circumstances under which each radiopharmaceutical compound is the compound of choice. Considerations of cost, ease of use, reliability, dosage, and ...

journal_title：American journal of hypertension

authors： Blaufox MD,Dubovsky EV,Hilson AJ,Taylor A Jr,de Zeeuw R

更新日期：1991-12-01 00:00:00

abstract：:Vasoconstrictor and Na/K pump inhibitory properties of a bufodienolide Na/K-ATPase inhibitor, marinobufagenin, were studied in isolated rings of 2 to 3 order branches of human pulmonary arteries respectively. Marinobufagenin displayed concentration-dependent vasoconstrictor activity (0.01 to 10 mmol/L). In sarcolemma ...

journal_title：American journal of hypertension

authors： Bagrov AY,Dmitrieva RI,Fedorova OV,Kazakov GP,Roukoyatkina NI,Shpen VM

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Pulse pressure (PP) is an independent predictor of cardiovascular and/or all-cause mortality in patients with underlying cardiovascular disease. We examined whether PP can be used to predict overall mortality in peritoneal dialysis (PD) patients. METHODS:We studied 153 PD patients (mean age, 54.5 +/- 14.2 y...

journal_title：American journal of hypertension

authors： Liu JH,Chen CC,Wang SM,Chou CY,Liu YL,Kuo HL,Lin HH,Wang IK,Yang YF,Huang CC

更新日期：2008-12-01 00:00:00

abstract：:Several classes of antihypertensive drugs have been shown to improve vascular function through mechanisms other than reducing blood pressure (BP) alone. Certain dihydropyridine calcium channel blockers (CCBs) and inhibitors of the renin-angiotensin system (RAS) increase nitric oxide (NO) bioavailability and decrease o...

journal_title：American journal of hypertension

authors： Mizuno Y,Jacob RF,Mason RP

更新日期：2008-10-01 00:00:00

abstract：:The Na-K-Cl cotransport activity in red blood cells from essential hypertensive men with low (n = 8, mean age 42 +/- 4 years) or normal renin activity (n = 4, mean age 43 +/- 3 years), and in normotensive men with normal renin activity (n = 7, mean age 38 +/- 4 years) has been evaluated by means of a recently develope...

journal_title：American journal of hypertension

authors： Cacciafesta M,Ferri C,Carlomagno A,De Angelis C,Scuteri A,Guidoni L,Luciani AM,Rosi A,Viti V,Santucci A

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:The adverse association between blood pressure and carotid artery intima-media thickness (IMT), a surrogate measure of subclinical atherosclerosis, is well-known. However, whether the G-6A polymorphism of the angiotensinogen (AGT) gene, a candidate gene of hypertension and vascular remodeling, modulates this...

journal_title：American journal of hypertension

authors： Bhuiyan AR,Chen W,Srinivasan SR,Rice J,Mock N,Tang R,Bond MG,Boerwinkle E,Berenson GS

更新日期：2007-10-01 00:00:00

abstract：:The influence of increased lability of blood pressure on the development of aortic atherosclerosis was examined. Because sinoaortic denervation (SAD) produced increased lability of blood pressure without blood pressure elevation, the development of atheromatous plaque was examined in SAD rats. These rats were fed a hi...

journal_title：American journal of hypertension

authors： Sasaki S,Yoneda Y,Fujita H,Uchida A,Takenaka K,Takesako T,Itoh H,Nakata T,Takeda K,Nakagawa M

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:We compared the cost-effectiveness of hypertension treatment in non-Hispanic blacks and non-Hispanic whites according to 2014 US hypertension treatment guidelines. METHODS:The cardiovascular disease (CVD) policy model simulated CVD events, quality-adjusted life years (QALYs), and treatment costs in 35- to 7...

journal_title：American journal of hypertension

authors： Vasudeva E,Moise N,Huang C,Mason A,Penko J,Goldman L,Coxson PG,Bibbins-Domingo K,Moran AE

更新日期：2016-10-01 00:00:00

abstract：:Hypertension is a common condition that is often seen in patients with diabetes. Both diseases increase the risk of morbidity and mortality from CV events and kidney disease progression. Factors that influence blood pressure (BP) control in diabetes include the persons' genetic background for hypertension and kidney d...

journal_title：American journal of hypertension

authors： Ali W,Bakris GL

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:Hypertension varies in prevalence among race/ethnic groups in the United States. Within-ethnic group differences associated with acculturation have been less frequently examined. We studied the association of three measures of acculturation (language spoken at home, place of birth, and years living in the US...

journal_title：American journal of hypertension

authors： Moran A,Diez Roux AV,Jackson SA,Kramer H,Manolio TA,Shrager S,Shea S

更新日期：2007-04-01 00:00:00

abstract：:Leptin, the gene product of the ob gene, is influenced by gender and insulin sensitivity. Because in human hypertension there are important endocrine-hemodynamic gender-dependent differences, we compared plasma leptin in 39 essential hypertensives (EH) and in 27 normotensive healthy subjects (HS) matched for gender, a...

journal_title：American journal of hypertension

authors： Mallamaci F,Cuzzola F,Tripepi G,Cutrupi S,Parlongo S,Tripepi R,Zoccali C

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Aim of this study was to evaluate the effect of the telmisartan-amlodipine combination at different doses on urinary albumin excretion rate (UAER) in hypertensive diabetic patients with microalbuminuria. METHODS:After a 2-week placebo period, 300 hypertensive patients with type 2 diabetes and microalbuminur...

journal_title：American journal of hypertension

authors： Fogari R,Derosa G,Zoppi A,Preti P,Lazzari P,Destro M,Fogari E,Rinaldi A,Mugellini A

更新日期：2007-04-01 00:00:00

abstract：:Congenital protein C deficiency is now widely recognized as a genetic risk for venous thrombosis. However, it remains uncertain whether this condition also confers risk for arterial thrombosis. We evaluated the association of congenital protein C deficiency with hypertension and silent cerebrovascular disease using br...

journal_title：American journal of hypertension

authors： Kario K,Sakata T,Higashikawa M,Katayama Y,Hoshide S,Shimada K,Miyata T

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:In hypertensives, nondippers are more likely than dippers to suffer silent, as well as overt, hypertensive target organ damage. In this study, we investigated whether a nondipper status was associated with target organ damage in normotensives. METHODS:We performed ambulatory blood pressure (BP) monitoring, ...

journal_title：American journal of hypertension

authors： Hoshide S,Kario K,Hoshide Y,Umeda Y,Hashimoto T,Kunii O,Ojima T,Shimada K

更新日期：2003-06-01 00:00:00

abstract：:The insulin sensitivity of five essential hypertensive patients was compared to five patients with renovascular hypertension, five patients with primary hyperaldosteronism, and five normotensive subjects, using the euglycemic hyperinsulinemic clamp technique. Essential hypertensive patients had significantly lower ins...

journal_title：American journal of hypertension

authors： Shamiss A,Carroll J,Rosenthal T

更新日期：1992-01-01 00:00:00

abstract：:Echocardiography (ECHO) is useful to document changes in left ventricular mass (LVM) in groups of patients, but may be too variable for use in the individual patient. Magnetic resonance imaging (MRI) may be a more precise and reliable method to quantify the mass of the left ventricule. This study reports the accuracy,...

journal_title：American journal of hypertension

authors： Bottini PB,Carr AA,Prisant LM,Flickinger FW,Allison JD,Gottdiener JS

更新日期：1995-03-01 00:00:00