Hypotensive effects of the lipoxygenase inhibitor phenidone in two-kidney, one clip Goldblatt hypertension.

abstract：:The aim of this study was to examine the effects of long-term continuous intracerebroventricular (icv) infusion of metformin on blood pressure (BP) in spontaneously hypertensive rats (SHR). To accelerate the development of hypertension, SHR were fed a 8% NaCl diet during the 3-week study period. Metformin was given in...

journal_title：American journal of hypertension

authors： Petersen JS,Andersen D,Muntzel MS,Diemer NH,Holstein-Rathlou NH

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:The relationship between regular physical activity, measured objectively and by self-report, and the circadian pattern of 24-hour ambulatory arterial blood pressure (BP) has not been clarified. METHODS:We performed a cross-sectional study in a cohort of healthy patients. We included 1,345 patients from the ...

journal_title：American journal of hypertension

authors： García-Ortiz L,Recio-Rodríguez JI,Puig-Ribera A,Lema-Bartolomé J,Ibáñez-Jalón E,González-Viejo N,Guenaga-Saenz N,Agudo-Conde C,Patino-Alonso MC,Gomez-Marcos MA,EVIDENT Group.

更新日期：2014-05-01 00:00:00

abstract：:The effects of long-term oral administration of quinapril on the occurrence of stroke and on mortality were investigated in young salt-loaded stroke-prone spontaneously hypertensive rats (SHR-SPs) during the treatment period (8th-34th week of age) and up to 6 weeks thereafter. Simultaneously, blood pressure, saline in...

journal_title：American journal of hypertension

authors： Vacher E,Fornes P,Domergue V,Richer C,Bruneval P,Giudicelli JF

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Hypertension is a significant global public health challenge. Low-grade inflammation is known to facilitate the development of essential hypertension and target-organ hypertensive damage. Neutrophil to lymphocyte ratio (NLR) is a simple and reliable indicator of inflammation that may also be useful in the pr...

journal_title：American journal of hypertension

authors： Liu X,Zhang Q,Wu H,Du H,Liu L,Shi H,Wang C,Xia Y,Guo X,Li C,Bao X,Su Q,Sun S,Wang X,Zhou M,Jia Q,Zhao H,Song K,Niu K

更新日期：2015-11-01 00:00:00

abstract：:Previous studies from our laboratories have demonstrated a selective increase in stores of atrial natriuretic peptide (ANP) in the anterior hypothalamus of NaCl-sensitive spontaneously hypertensive rats (SHR-S) compared to NaCl-resistant Wistar-Kyoto (WKY) controls and have suggested that anterior hypothalamic ANP con...

journal_title：American journal of hypertension

authors： Jin HK,Yang RH,Chen YF,Wyss JM,Oparil S

更新日期：1991-05-01 00:00:00

abstract：:High levels of plasma homocyst(e)ine (H[e]) are associated with increased vascular risk. Treatment is being contemplated, but the level at which patients should be treated is not known. We compared the response of carotid plaque to vitamin therapy in patients with H(e) above and below 14 micromol/L, a level commonly r...

journal_title：American journal of hypertension

authors： Hackam DG,Peterson JC,Spence JD

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:In patients free from overt cardiac disease, R wave in aVL lead (RaVL) is strongly correlated with left ventricular mass index (LVMI) assessed by transthoracic echocardiography. The aim of the present study was to extend this finding to other settings (cardiomyopathy or conduction disorders), by comparing EC...

journal_title：American journal of hypertension

authors： Courand PY,Grandjean A,Charles P,Paget V,Khettab F,Bricca G,Boussel L,Lantelme P,Harbaoui B

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:The present study examined the inhibitory action of temporary treatment with an angiotensin type 1 (AT(1)) receptor blocker (ARB) on vascular remodeling using hypertensive mice with overexpression of the human renin (hRN) and angiotensinogen (hANG) genes. METHODS:hRN/hANG transgenic mice (hRN/hANG-Tg) were ...

journal_title：American journal of hypertension

authors： Inaba S,Iwai M,Furuno M,Kanno H,Senba I,Okayama H,Mogi M,Higaki J,Horiuchi M

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:This birth cohort study was conducted to investigate the contribution of prenatal and antenatal environmental exposures to later-life hypertensive status. METHODS:Two thousand five hundred and three individuals born in 1921-1954 at the Peking Union Medical College Hospital (PUMCH) were targeted; 2,081 (83.1...

journal_title：American journal of hypertension

authors： Chen X,Zhang ZX,George LK,Wang ZS,Fan ZJ,Xu T,Zhou XL,Han SM,Wen HB,Zeng Y

更新日期：2012-04-01 00:00:00

abstract：:Increased dietary sodium intake has been associated with an increase in blood pressure as well as a decrease in insulin-mediated glucose disposal in young healthy adults. The purpose of this study was to determine whether dietary sodium intake is associated with changes in oral glucose tolerance, insulin sensitivity, ...

journal_title：American journal of hypertension

authors： Dengel DR,Mayuga RS,Kairis GM,Goldberg AP,Weir MR

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:The optimal schedule for self-monitoring home BP (SMHBP) readings is enormously important in the diagnosis of different phenotypes related to hypertension. The aim of this study was to determine the prognostic capacity of a 3-day SMHBP schedule when using or suppressing the first-day measurements in compilin...

journal_title：American journal of hypertension

authors： Bayó J,Dalfó A,Barceló MA,Saez M,Roca C,Pallozzi J,Coll-De-Tuero G

更新日期：2020-02-22 00:00:00

abstract：BACKGROUND:This study investigated the relationship of ethnicity to the differences between blood pressure (BP) measured in a clinic setting and by ambulatory blood pressure monitoring (ABPM) in individuals with a previous diagnosis of hypertension (HT) and without a previous diagnosis of hypertension (NHT). METHODS:A...

journal_title：American journal of hypertension

authors： Martin U,Haque MS,Wood S,Greenfield SM,Gill PS,Mant J,Mohammed MA,Heer G,Johal A,Kaur R,Schwartz C,McManus RJ

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Carvedilol is known to be an adrenoreceptor blocker and free radical scavenger, used in hypertension and cardiac failure. However, its therapeutic actions cannot be fully explained by these mechanisms. In these studies, we tested the hypothesis that carvedilol action is associated with the synthesis/release ...

journal_title：American journal of hypertension

authors： Afonso RA,Patarrao RS,Macedo MP,Carmo MM

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Whether left ventricular (LV) geometric remodeling, as indexed by relative wall thickness (RWT), aggregates in families and is inherited independent of LV mass (LVM) and additional confounders is uncertain. METHODS:We determined whether RWT as assessed from 2D targeted M-mode echocardiography shows intrafam...

journal_title：American journal of hypertension

authors： Peterson VR,Norton GR,Redelinghuys M,Libhaber CD,Maseko MJ,Majane OH,Brooksbank R,Woodiwiss AJ

更新日期：2015-05-01 00:00:00

abstract：:The objective of this study was to evaluate whether the major histocompatibility complex of the rat can be related to blood pressure (BP) level and BP response to stress. Blood pressure was determined under light ether anesthesia or during moderate restraint stress in normotensive Lewis rats, in rat strains congenic w...

journal_title：American journal of hypertension

authors： Kunes J,Kohoutová M,Zicha J

更新日期：1996-07-01 00:00:00

abstract：:Mesangial cells in the glomerulus have several important physiological functions, as has been demonstrated by past research. Platelet derived growth factor, thrombin, endothelin, and angiotensin II have all been shown to affect mesangial cell growth and protein synthesis. First generation Ca channel blockers also have...

journal_title：American journal of hypertension

authors： Shultz PJ,Raij L

更新日期：1992-12-01 00:00:00

abstract：:Further improvement in blood pressure control at the population level will result from dealing with hard-to-solve problems, such as access to care, long-term management of a chronic disease, and societal influences on lifestyle. Additional knowledge and experimental data are needed, reinforced by clear public health c...

journal_title：American journal of hypertension

authors： Lang T

更新日期：1998-07-01 00:00:00

abstract：:Congenital protein C deficiency is now widely recognized as a genetic risk for venous thrombosis. However, it remains uncertain whether this condition also confers risk for arterial thrombosis. We evaluated the association of congenital protein C deficiency with hypertension and silent cerebrovascular disease using br...

journal_title：American journal of hypertension

authors： Kario K,Sakata T,Higashikawa M,Katayama Y,Hoshide S,Shimada K,Miyata T

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Hypertension is the most prevalent chronic disease worldwide. Lifestyle behaviors for its prevention and control are recommended within worldwide guidelines. Nevertheless, their combined relationship with blood pressure (BP) level, particularly in the general population, would need more investigations. Our a...

journal_title：American journal of hypertension

authors： Lelong H,Galan P,Kesse-Guyot E,Fezeu L,Hercberg S,Blacher J

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Calcium channel blockers such as amlodipine are effective antihypertensive agents. In this study we investigated the effects of amlodipine on vascular oxidative stress, expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1), and endothelial function in angiotensin (Ang) II-infused ra...

journal_title：American journal of hypertension

authors： Zhou MS,Jaimes EA,Raij L

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:The reduction of coronary flow reserve (CFR) found in arterial hypertension may be due to changes in afterload, left ventricular (LV) structure, and metabolic factors. Also, insulin-like growth factor-1 (IGF-1) may be associated with the magnitude of CFR in relation to its modulating action on cardiac and en...

journal_title：American journal of hypertension

authors： Galderisi M,Caso P,Cicala S,De Simone L,Barbieri M,Vitale G,de Divitiis O,Paolisso G

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Previous reports have demonstrated the antihypertensive efficacy of high doses of spironolactone in subjects with primary aldosteronism and, to a lesser degree, subjects with resistant hypertension. METHODS:In current analysis, we examined the antihypertensive benefit of adding low-dose spironolactone to mu...

journal_title：American journal of hypertension

authors： Nishizaka MK,Zaman MA,Calhoun DA

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Nocturnal hypertension is an important phenotype of abnormal diurnal blood pressure (BP) variability and a known risk marker for target organ damage and cardiovascular events. This study aimed to assess the differential BP-lowering effects of esaxerenone vs. eplerenone on nocturnal BP in hypertensive patient...

journal_title：American journal of hypertension

authors： Kario K,Ito S,Itoh H,Rakugi H,Okuda Y,Yoshimura M,Yamakawa S

更新日期：2020-11-09 00:00:00

abstract：BACKGROUND:Central aortic blood pressure (CBP) and CBP-derived parameters are independent predictors of cardiovascular risk. Angiotensin II receptor blockers (ARBs) or angiotensin-converting enzyme inhibitors plus calcium channel blockers are the recommended first-line treatments in hypertensive diabetic patients; howe...

journal_title：American journal of hypertension

authors： Redon J,Pichler G,Missed Dose Study Group.

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Nocturnal blood pressure (BP) is associated with risk for cardiovascular events. However, the relationship between nocturnal BP in young adults and cognitive function in midlife remains unclear. METHODS:We used data from the ambulatory BP monitoring substudy of the Coronary Artery Risk Development in Young ...

journal_title：American journal of hypertension

authors： Yano Y,Ning H,Muntner P,Reis JP,Calhoun DA,Viera AJ,Levine DA,Jacobs DR Jr,Shimbo D,Liu K,Greenland P,Lloyd-Jones D

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate (i) the effect of nebivolol, a selective beta1-adrenergic receptor antagonist, on plasma concentration of asymmetric dimethylarginine (ADMA) and on flow-mediated dilation (FMD) in essential hypertensive patients; (ii) the effect of serum derived from the treated hypertens...

journal_title：American journal of hypertension

authors： Pasini AF,Garbin U,Stranieri C,Boccioletti V,Mozzini C,Manfro S,Pasini A,Cominacini M,Cominacini L

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Few population studies have described the heritability and intrafamilial concordance of the retinal microvessels, or the genetic or environmental correlations of the phenotypes of these vessels. METHODS:We randomly selected 413 participants from 70 families (mean age, 51.5 years; 50.1% women) from a Flemish...

journal_title：American journal of hypertension

authors： Liu YP,Kuznetsova T,Jin Y,Thijs L,Asayama K,Gu YM,Bochud M,Verhamme P,Struijker-Boudier HA,Staessen JA

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The effect of age on the augmentation index (AI) differs between young adults and the elderly, and the AI reaches a plateau after the age of 60 years. We examined whether the effects of age and an elevation in blood pressure on the AI differ between young adults and the elderly, between subjects with and wit...

journal_title：American journal of hypertension

authors： Tomiyama H,Odaira M,Kimura K,Matsumoto C,Shiina K,Eguchi K,Miyashita H,Shimada K,Yamashina A

更新日期：2014-12-01 00:00:00

abstract：:We previously showed that the lymphocyte proliferation response was significantly suppressed in spontaneously hypertensive rats (SHR) and that this depressed response was due to excessive production of nitric oxide (NO) in macrophages and vascular smooth muscle cells (VSMC). Whether lymphocyte depression and activatio...

journal_title：American journal of hypertension

authors： Xiao J,Pang PK

更新日期：1996-04-01 00:00:00

abstract：:Decreased urinary kallikrein excretion has been shown to be related to hypertension. Kallikrein levels also have been shown to be determined primarily by genes, with 51% of the total variance being due to a single gene. However, there exists strong spouse-spouse correlation, indicating that common environment plays a ...

journal_title：American journal of hypertension

authors： Hunt SC,Wu LL,Slattery ML,Meikle AW,Williams RR

更新日期：1993-03-01 00:00:00