Altered stores of atrial natriuretic peptide in specific brain nuclei of NaCl-sensitive spontaneously hypertensive rats.

abstract：:The process whereby a physician explains to the ill patient what has gone wrong and what can be done about it can be taught and evaluated by simulated patients (SPIs). This study was designed to determine whether a training experience in educating a diabetic SPI improves subsequent performance with a hypertensive SPI....

journal_title：American journal of hypertension

authors： Zweifler AJ,Sisson JC,Wolf FM,Trabin NL,Dicken LL,Gruppen LD,Grum CM,Baum KD

更新日期：1998-05-01 00:00:00

abstract：:Alterations in Na, K ATPase pump activity as well as erythrocyte (RBC) intracellular sodium concentration (Nai) have been demonstrated in humans and rats with established hypertension. The contribution of hypertension itself to these changes is unclear. Accordingly, we investigated RBC ion transport and plasma ouabain...

journal_title：American journal of hypertension

authors： McCormick CP,Hennessy JF,Rauch AL,Buckalew VM Jr

更新日期：1989-08-01 00:00:00

abstract：:The increased red blood cell Li+/Na+ exchange found in a subgroup of patients with essential hypertension (EH) may reflect an increased activity of the Na+/H+ exchange. The maximal velocity of the red cells' Na+/H+ (Na+ influx promoted by an outward H+ gradient) and Li+/Na+ (Li+ efflux promoted by external Na+) exchan...

journal_title：American journal of hypertension

authors： Semplicini A,Canessa M,Mozzato MG,Ceolotto G,Marzola M,Buzzaccarini F,Casolino P,Pessina AC

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Dyslipidemia in hypertensive sibships may be characterized by atherogenic small low-density lipoprotein (LDL) particles. Whether LDL particle size is associated with the extent of coronary atherosclerosis in hypertensive sibships is unknown. METHODS:Subjects (n = 792, mean age 62 years, 60% women) were asce...

journal_title：American journal of hypertension

authors： Kullo IJ,Bailey KR,McConnell JP,Peyser PA,Bielak LF,Kardia SL,Sheedy PF 2nd,Boerwinkle E,Turner ST

更新日期：2004-09-01 00:00:00

abstract：:The present study was designed to investigate the role of the autonomic nervous system in experimental hypertension induced by chronic administration of N-nitro-L-arginine methyl ester (L-NAME) in the drinking water (1 mg/mL) over 6 days. L-NAME ingestion caused a large rise in resting mean arterial pressure (MAP) (17...

journal_title：American journal of hypertension

authors： Cunha RS,Cabral AM,Vasquez EC

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Evaluating effect of acute or chronic use of antihypertensives on risk of falls in older adults. METHODS:Data sources: Systematic search of primary research articles in CINAHL, Cochrane, EBM, EMBASE, and MEDLINE databases from January 1 2007 to June 1 2017. Study selection: Research studies of cohort, case-...

journal_title：American journal of hypertension

authors： Kahlaee HR,Latt MD,Schneider CR

更新日期：2018-03-10 00:00:00

abstract：BACKGROUND:Epidemiologic analysis of family data on blood pressure (BP) is often compromised by the effects of antihypertensive medications. A review of numerous clinical trials that investigated the effects of BP-lowering medications is summarized here. METHODS:Published clinical trials, including 137 clinical trials...

journal_title：American journal of hypertension

authors： Wu J,Kraja AT,Oberman A,Lewis CE,Ellison RC,Arnett DK,Heiss G,Lalouel JM,Turner ST,Hunt SC,Province MA,Rao DC

更新日期：2005-07-01 00:00:00

abstract：:The peak incidence of cardiovascular complications in the morning points to a possible role of the abrupt increase in blood pressure on arising. However, there is as yet no firm evidence linking the extent of the elevation in blood pressure on arising and the risk of cardiovascular complications. We sought a correlati...

journal_title：American journal of hypertension

authors： Gosse P,Ansoborlo P,Lemetayer P,Clementy J

更新日期：1997-05-01 00:00:00

abstract：:Hypertensive renal injury is a major identifiable cause of end-stage renal disease in African-Americans. A complex nexus of sociologic, biologic, environmental, and sociocultural variables are involved in mediating this risk and interrelate with dietary salt consumption and salt sensitivity. It is likely that dietary ...

journal_title：American journal of hypertension

authors： Weir MR

更新日期：1995-06-01 00:00:00

abstract：:Barriers to high blood pressure (HBP) care and control have been reported in the literature for > 30 years. Few reports on barriers, however, have focused on the young black man with HBP, the age/sex/race group with the highest rates of early severe and complicated HBP and the lowest rates of awareness, treatment, and...

journal_title：American journal of hypertension

authors： Hill MN,Bone LR,Kim MT,Miller DJ,Dennison CR,Levine DM

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:It is unknown whether the physiological impact of a given blood pressure (BP) varies by body size. We explored interactions between higher vs. lower systolic BP (SBP) targets and anthropometric measures (body mass index (BMI), body surface area (BSA), height, weight) and recurrent stroke and death in the Sec...

journal_title：American journal of hypertension

authors： Field TS,McClure LA,White CL,Pergola PE,Hart RG,Benavente OR,Hill MD,SPS3 Investigators.

更新日期：2015-06-01 00:00:00

abstract：:Stroke-prone spontaneously hypertensive rats (SHRSP), subjected to high NaCl, show severe hypertension, organ damage, and early death. Preventive treatment with angiotensin II type 1 (AT1) receptor antagonists is known to be effective. Previously, we found that angiotensin converting enzyme (ACE) inhibition could redu...

journal_title：American journal of hypertension

authors： Blezer EL,Nicolay K,Koomans HA,Joles JA

更新日期：2001-01-01 00:00:00

abstract：:There is controversy over whether endothelial function is impaired in human essential hypertension. All studies to date have used measurements of forearm blood flow by plethysmography to assess endothelium-dependent vasodilation and endothelial function. In contrast to these studies, which have focused on resistance v...

journal_title：American journal of hypertension

authors： Schmieder RE,Weihprecht H,Schobel H,John S,Weidinger G,Gatzka C,Veelken R

更新日期：1997-03-01 00:00:00

abstract：:To clarify characteristics of the patients in whom exercise training lowers blood pressure and to elucidate the mechanisms by which exercise training lowers blood pressure, we evaluated 24-h blood pressure, glomerular filtration rate (GFR), renal blood flow (RBF), filtration fraction (FF), plasma renin activity (PRA),...

journal_title：American journal of hypertension

authors： Kohno K,Matsuoka H,Takenaka K,Miyake Y,Nomura G,Imaizumi T

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:This study analyzed whether hypertension induced by N(omega)-nitro-l-arginine methyl ester (L-NAME) is associated with dysregulation of the main antioxidant enzymes (superoxide dismutase [SOD], catalase, glutathione peroxidase [GPX], and glutathione reductase [GR]) and whether chronic administration of tempo...

journal_title：American journal of hypertension

authors： Sainz J,Wangensteen R,Rodríguez Gómez I,Moreno JM,Chamorro V,Osuna A,Bueno P,Vargas F

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Left ventricular (LV) concentric geometry and hypertrophy, depressed wall mechanics, and abnormal diastolic properties have been described in the diabetic heart. However, the cardiac response to dynamic exercise in diabetic patients remains controversial. The present study assessed strain rate (SR) imaging d...

journal_title：American journal of hypertension

authors： Galderisi M,de Simone G,Innelli P,Turco A,Turco S,Capaldo B,Riccardi G,de Divitiis O

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Despite readily available treatments, control of blood pressure (BP) with population aging remains suboptimal. Further, there are gaps in the understanding of the management of high BP in the aged. We explored antihypertensive treatment and control among elderly hypertensive participants free from overt card...

journal_title：American journal of hypertension

authors： Chowdhury EK,Nelson MR,Ernst ME,Margolis KL,Beilin LJ,Johnston CI,Woods RL,Murray AM,Wolfe R,Storey E,Shah RC,Lockery JE,Tonkin AM,Newman AB,Williamson JD,Abhayaratna WP,Stocks NP,Fitzgerald SM,Orchard SG,Trevaks RE

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The renin-angiotensin system (RAS) plays a major role in promoting left ventricular (LV) remodeling in essential hypertension. We designed a controlled, randomized pilot study aimed to test the hypothesis that the dual RAS blockade with angiotensin-converting enzyme (ACE) inhibitor (ACEi) + angiotensin II re...

journal_title：American journal of hypertension

authors： Grandi AM,Solbiati F,Laurita E,Maresca AM,Nicolini E,Marchesi C,Gianni M,Guasti L,Venco A

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Increased short-term blood pressure (BP) variability (BPV) in hemodialysis is associated with increased cardiovascular and all-cause mortality. Studies on the impact of BP-lowering interventions on BPV are scarce. This study examined the effect of dry-weight reduction with a lung ultrasound-guided strategy o...

journal_title：American journal of hypertension

authors： Loutradis C,Sarafidis PA,Theodorakopoulou M,Ekart R,Alexandrou ME,Pyrgidis N,Angeloudi E,Tzanis G,Toumpourleka M,Papadopoulou D,Mallamaci F,Zoccali C,Papagianni A

更新日期：2019-07-17 00:00:00

abstract：:Angiotensin receptors became relatively easy to study when radioactive derivatives of the peptide were synthesized for radioimmunoassays. Binding assays in vitro led to the discovery of receptors in many tissues different from those involved in the classic actions of angiotensin. The physiologic significance of recept...

journal_title：American journal of hypertension

authors： Goodfriend TL

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Despite an association between visit-to-visit blood pressure (BP) variability (VV-BPV) and cardiovascular (CV) outcomes, many studies performed during the past 4 years have shown conflicting results. This study investigated the impact of VV-BPV on CV outcomes in the Korean National Health Insurance Service (...

journal_title：American journal of hypertension

authors： Choi S,Shin J,Choi SY,Sung KC,Ihm SH,Kim KI,Kim YM

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The role of pulsatile hemodynamics in the management of patients with acute heart failure syndrome (AHFS) remains to be elucidated. We investigated the changes of the pulsatile hemodynamics along the hospital course of AHFS in relation to short-term outcomes. METHODS:A total of 80 AHFS patients (73.2 ± 14.1...

journal_title：American journal of hypertension

authors： Sung SH,Yu WC,Cheng HM,Chuang SY,Wang KL,Huang CM,Chen CH

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:There is conflicting information with regard to the effect of beta-blockers on arterial stiffness and wave reflection. We compared a vasodilating beta-blocker, nebivolol, with atenolol. METHODS:We randomized 40 subjects with untreated hypertension (mean +/- s.e.m. systolic/diastolic blood pressure (BP) of 1...

journal_title：American journal of hypertension

authors： Mahmud A,Feely J

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Reduced synthesis of nitric oxide (NO) is considered a major proatherogenic mechanism in patients with end-stage renal disease (ESRD), but genetic factors impinging on this mechanism have been little studied in this population. METHODS:We tested the relationship between carotid intima-media thickness (IMT) ...

journal_title：American journal of hypertension

authors： Spoto B,Benedetto FA,Testa A,Tripepi G,Mallamaci F,Maas R,Boeger RH,Zoccali C

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Experimentally induced sleep deprivation can raise blood pressure (BP) and worsen hypertension. We recently reported a significantly higher prevalence of obstructive sleep apnea (OSA) and reduced rapid eye movement (REM) sleep time in drug-resistant hypertensives compared to controlled hypertensives. The obj...

journal_title：American journal of hypertension

authors： Friedman O,Bradley TD,Ruttanaumpawan P,Logan AG

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Central systolic blood pressure (SBP) can be estimated by an oscillometric method developed from a pulse volume plethysmography (PVP) device. The present study applied this novel method to a noninvasive blood pressure monitor (NBPM). METHODS:We enrolled 50 patients (37 men, age range 30-84 years) referred f...

journal_title：American journal of hypertension

authors： Sung SH,Cheng HM,Chuang SY,Shih YT,Wang KL,Chen YH,Lin SJ,Yu WC,Chen CH

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Ischemia-induced reactive hyperemia (RH) is mediated by various factors including release of nitric oxide (NO). The contribution of NO to RH equals the extent of L-NMMA-dependent reduction of forearm blood flow (FBF). Because the optimal duration and location of ischemia that provokes maximum NO activation i...

journal_title：American journal of hypertension

authors： Raff U,Ott C,John S,Schmidt BM,Fleischmann EH,Schmieder RE

更新日期：2010-08-01 00:00:00

abstract：:Increased dietary K+ increases plasma [K+] and is linked to or associated with reduced mortality from stroke and reduced blood pressure in humans and animals. We hypothesized that physiologic increases in extracellular [K+] ([K]o) directly inhibit cultured vascular smooth muscle cell (VSMC) proliferation. Studies were...

journal_title：American journal of hypertension

authors： McCabe RD,Young DB

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Recent reports suggesting that primary aldosteronism (PA) is more common than historically thought have often relied on use of the plasma aldosterone concentration (PAC) to plasma renin activity (PRA) ratio (ARR) to identify patients with PA. Prior determinations of the validity of the ARR had been generally...

journal_title：American journal of hypertension

authors： Nishizaka MK,Pratt-Ubunama M,Zaman MA,Cofield S,Calhoun DA

更新日期：2005-06-01 00:00:00

abstract：:The effects of activators and inhibitors of protein kinase C (PKC) on the production of C-type natriuretic peptide (CNP) by cultured human aortic endothelial cells were examined. The PKC activators phorbol 12-myristate 13-acetate (PMA) and 1-oleoyl 2-acetyl glycerol (OAG) stimulated CNP release; the maximal effects we...

journal_title：American journal of hypertension

authors： Yamada Y,Yokota M

更新日期：1996-09-01 00:00:00