Barriers to hypertension care and control in young urban black men.


:Barriers to high blood pressure (HBP) care and control have been reported in the literature for > 30 years. Few reports on barriers, however, have focused on the young black man with HBP, the age/sex/race group with the highest rates of early severe and complicated HBP and the lowest rates of awareness, treatment, and control. In a randomized clinical trial of comprehensive care for hypertensive young urban black men, factors potentially associated with care and control were assessed at baseline for the 309 enrolled men. A majority of the men encountered a variety of barriers including economic, social, and lifestyle obstacles to adequate BP care and control, including no current HBP care (49%), risk of alcoholism (62%), use of illicit drugs (45%), social isolation (47%), unemployment (40%), and lack of health insurance (51%). Having health insurance (odds ratio = 7.20, P = .00) and a negative urine drug screen (odds ratio = .56, P = .04) were significant predictors of being in HBP care. Low alcoholism risk and employment were identified as significant predictors of compliance with HBP medication-taking behavior. Men currently using illicit drugs were 2.64 times less likely to have controlled BP compared with their counterparts who did not use illicit drugs, and men currently taking HBP medication were 63 times more likely have controlled BP compared with men not taking HBP medication. Comprehensive interventions are needed to address socioeconomic and lifestyle issues as well as other barriers to care and treatment, if HBP care is to be salient and effective in this high risk group.


Am J Hypertens


Hill MN,Bone LR,Kim MT,Miller DJ,Dennison CR,Levine DM




Has Abstract


1999-10-01 00:00:00




10 Pt 1










  • Higher cholesterol and insulin levels in pregnancy are associated with increased risk for pregnancy-induced hypertension.

    abstract::Hyperinsulinemia and dyslipidemia are known to be associated with essential hypertension but their role in pregnancy-induced hypertension remains unclear. We performed a case-control study comparing cholesterol, insulin, and glucose levels in the early third trimester of pregnancy among 31 women who developed pregnanc...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Solomon CG,Carroll JS,Okamura K,Graves SW,Seely EW

    更新日期:1999-03-01 00:00:00

  • Endothelin: key mediator of hypertension in preeclampsia.

    abstract::Preeclampsia is a pregnancy-induced hypertensive disorder characterized by proteinuria and widespread maternal endothelial dysfunction. It remains one of the most common disorders in pregnancy and remains one of the leading causes of maternal and fetal morbidity. Recent research has revealed that placental insufficien...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,评审


    authors: George EM,Granger JP

    更新日期:2011-09-01 00:00:00

  • Therapeutic benefit of captopril in salt-loaded stroke-prone spontaneously hypertensive rats is independent of hypotensive effect.

    abstract::In the present study we examined whether the angiotensin I converting enzyme inhibitor, captopril, would protect stroke-prone spontaneously hypertensive rats (SHRSP) from stroke and renal pathology over a 26-week period. In the control group of six untreated SHRSP fed Stroke-Prone Rodent Diet and 1% NaCl drinking solu...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Stier CT Jr,Chander P,Gutstein WH,Levine S,Itskovitz HD

    更新日期:1991-08-01 00:00:00

  • The influence of physical activity on the variability of ambulatory blood pressure.

    abstract::The aim of this study was to assess the contribution of physical activity levels to blood pressure (BP) variability, and to assess the effect age, gender, body mass index, and use of antihypertensive medications on this relationship. We simultaneously monitored 24-h ambulatory BP by automated recorder and activity by ...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Leary AC,Donnan PT,MacDonald TM,Murphy MB

    更新日期:2000-10-01 00:00:00

  • Dapagliflozin does not affect short-term blood pressure variability in patients with type-2 diabetes mellitus.

    abstract:BACKGROUND:Increased blood-pressure-variability (BPV) is associated with increased cardiovascular and all-cause mortality in patients with type 2 diabetes mellitus (T2DM). Sodium-glucose-co-transporter-2 (SGLT-2) inhibitors decrease the incidence of cardiovascular events, renal events, and death in this population. Thi...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Papadopoulou E,Theodorakopoulou MP,Loutradis C,Tzanis G,Tzatzagou G,Kotsa K,Zografou I,Tsapas A,Karagiannis A,Sarafidis P

    更新日期:2020-12-05 00:00:00

  • Lack of difference in oxalate-dependent Ca2+ uptake by membrane homogenate of African-American and white subjects.

    abstract::In order to further characterize previously described racial differences in intracellular Ca2+ homeostasis, the activity of sarcoplasmic-endoplasmic reticulum Ca2+-ATPase was measured in cultured skin fibroblasts from normotensive African-Americans and whites. Cells originated from apparently healthy, normotensive Afr...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Yang XY,Aviv A,Hopp L

    更新日期:1997-04-01 00:00:00

  • High K diets markedly reduce atherosclerotic cholesterol ester deposition in aortas of rats with hypercholesterolemia and hypertension.

    abstract::High K diets prevent hypertensive endothelial injury and intimal thickening. Cholesterol esters often deposit during hypercholesterolemia. Would a high K diet influence cholesterol ester deposits? In a normal rat on a normal diet, no cholesterol esters are detected in the aorta. Stroke prone SHR rats were fed for 3 mo...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Tobian L,Jahner TM,Johnson MA

    更新日期:1990-02-01 00:00:00

  • Lung Ultrasound-Guided Dry-Weight Reduction in Hemodialysis Patients Does Not Affect Short-Term Blood Pressure Variability.

    abstract:BACKGROUND:Increased short-term blood pressure (BP) variability (BPV) in hemodialysis is associated with increased cardiovascular and all-cause mortality. Studies on the impact of BP-lowering interventions on BPV are scarce. This study examined the effect of dry-weight reduction with a lung ultrasound-guided strategy o...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Loutradis C,Sarafidis PA,Theodorakopoulou M,Ekart R,Alexandrou ME,Pyrgidis N,Angeloudi E,Tzanis G,Toumpourleka M,Papadopoulou D,Mallamaci F,Zoccali C,Papagianni A

    更新日期:2019-07-17 00:00:00

  • Adipose tissue-specific regulation of angiotensinogen in obese humans and mice: impact of nutritional status and adipocyte hypertrophy.

    abstract:BACKGROUND:The adipose tissue renin-angiotensin system (RAS) has been implicated in the pathophysiology of obesity and dysfunction of adipose tissue. However, neither regulation of angiotensinogen (AGT) expression in adipose tissue nor secretion of adipose tissue-derived AGT has been fully elucidated in humans. METHOD...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Yasue S,Masuzaki H,Okada S,Ishii T,Kozuka C,Tanaka T,Fujikura J,Ebihara K,Hosoda K,Katsurada A,Ohashi N,Urushihara M,Kobori H,Morimoto N,Kawazoe T,Naitoh M,Okada M,Sakaue H,Suzuki S,Nakao K

    更新日期:2010-04-01 00:00:00

  • Differential inhibitory effects of antidiabetic drugs on arterial smooth muscle cell proliferation.

    abstract::We compared three drugs representing different classes of antidiabetic pharmacology (glyburide, a sulfonylurea; pioglitazone, a thiazolidinedione; and metformin, a biguanide) in terms of their direct effects on proliferation of cultured arterial smooth muscle cells (SMC). Rat aortic SMC were seeded at 4 x 10(4)/35 mm ...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Peuler JD,Phare SM,Iannucci AR,Hodorek MJ

    更新日期:1996-02-01 00:00:00

  • Aortic Fibrosis, Induced by High Salt Intake in the Absence of Hypertensive Response, is Reduced by a Monoclonal Antibody to Marinobufagenin.

    abstract:BACKGROUND:Marinobufagenin (MBG) is an endogenous Na/K-ATPase inhibitor, a natriuretic and a vasoconstrictor. MBG is implicated in salt-sensitive hypertension, cardiac hypertrophy, and initiate the pro-fibrotic signaling. Previously it was demonstrated that immunoneutralization of an endogenous MBG by 3E9 anti-MBG-anti...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Grigorova YN,Juhasz O,Zernetkina V,Fishbein KW,Lakatta EG,Fedorova OV,Bagrov AY

    更新日期:2016-05-01 00:00:00

  • Relationship Between Carotid Atherosclerosis and Pulse Pressure with Renal Hemodynamics in Hypertensive Patients.

    abstract:BACKGROUND:Structural atherosclerotic damage, arterial stiffness, pulse pressure (PP), and renal hemodynamics may interact and influence each other. Renal resistance index (RRI) appears as a good indicator of systemic vascular changes. The aim of our study was to assess the independent relationships of carotid intima-m...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Geraci G,Mulè G,Costanza G,Mogavero M,Geraci C,Cottone S

    更新日期:2016-04-01 00:00:00

  • Do beta-blockers really increase peripheral vascular resistance? Review of the literature and new observations under basal conditions.

    abstract::Most antihypertensive drugs act by counteracting vasoconstrictor mechanisms and lower blood pressure by lowering vascular resistance. The beta-blockers, which have the unique feature of counteracting cardiac sympathetic drive, seem to be a major exception to this generalization. Moreover, their degree of cardiodepress...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,评审


    authors: Man in't Veld AJ,Van den Meiracker AH,Schalekamp MA

    更新日期:1988-01-01 00:00:00

  • Hypertension, pulse, and other cardiovascular risk factors and vitamin D status in Finnish men.

    abstract:BACKGROUND:Debate exists about the relationship between hypovitaminosis D and cardiovascular (CVD) risk. METHODS:This study investigated baseline (n=2,271) 25-hydroxyvitamin D (25(OH)D) and baseline and 4 year (n=1,957) CVD risk in a cohort of Finnish middle-aged male smokers. RESULTS:The prevalences of measured hype...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Ke L,Graubard BI,Albanes D,Fraser DR,Weinstein SJ,Virtamo J,Brock KE

    更新日期:2013-08-01 00:00:00

  • Protective action of calcium channel antagonists in atherogenesis and experimental vascular injury.

    abstract::Experimental research using in vitro and in vivo models of vascular injury have delineated several common mechanisms that characterize the arterial damage in diseases such as atherosclerosis and hypertension. Changes in endothelial permeability, smooth muscle cell proliferation, and accumulation of connective tissue m...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,评审


    authors: Weinstein DB,Heider JG

    更新日期:1989-03-01 00:00:00

  • Aspirin test for differentiation of unilateral renovascular hypertension from hyperreninemic essential hypertension.

    abstract::Responses of renin release and blood pressure to aspirin DL-lysine (ASP) were examined to find out if the responses could help in the differentiation between unilateral renovascular hypertension (RVH) and hyperreninemic essential hypertension (EHT). The two studies involved ten patients with unilateral RVH, eight with...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Imanishi M,Ohta M,Kawamura M,Akabane S,Matsushima Y,Kuramochi M,Kojima S,Kimura K,Takamiya M,Ito K

    更新日期:1991-09-01 00:00:00

  • The independent and combined effects of weight loss and aerobic exercise on blood pressure and oral glucose tolerance in older men.

    abstract::The independent and combined effects of aerobic exercise training (AEX) and weight loss (WL) on blood pressure (BP) and oral glucose tolerance were studied in 97 nondiabetic, sedentary, older men. The men were assigned to either a WL (n = 31), AEX (n = 35), AEX+WL (n = 20) intervention, or to a control (CON) group (n ...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Dengel DR,Galecki AT,Hagberg JM,Pratley RE

    更新日期:1998-12-01 00:00:00

  • Impaired vasodilator capacity and exaggerated pressor response to isometric exercise in subjects with family history of hypertension.

    abstract::The nature of the cardiovascular response to isometric exercise is still debated. An adequate blood supply to exercising muscles at the onset of contraction seems to be an important factor controlling the extent of pressor response to isometric contraction. In comparison to normotensive subjects without familiar hyper...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Borghi C,Costa FV,Boschi S,Ambrosioni E

    更新日期:1988-07-01 00:00:00

  • The Influence of Sodium and Potassium Intake and Insulin Resistance on Blood Pressure in Normotensive Individuals Is More Evident in Women.

    abstract:BACKGROUND:Considering sex differences, salt sensitivity, and insulin resistance (IR), the effect of sodium restriction and increased potassium intake on blood pressure remains unclear in normotensive Asian individuals, compared to that in hypertensive patients. METHODS:To assess the influence of sodium and potassium ...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Murao S,Takata Y,Yasuda M,Osawa H,Kohi F

    更新日期:2018-07-16 00:00:00

  • Antihypertensive effects of angiotensin converting enzyme inhibition by lisinopril in post-transplant patients.

    abstract:BACKGROUND:It is not known whether strict control of blood pressure (BP) in mild post-transplant hypertension gives any benefit. Our primary objective was to test the antihypertensive effects of lisinopril added to standard therapy on ambulatory BP (ABP) of post-transplant patients. The secondary objective was to monit...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Opie LH,Haus M,Commerford PJ,Levetan B,Moore K,Brink J

    更新日期:2002-10-01 00:00:00

  • Age-related changes in membrane fluidity of erythrocytes in essential hypertension.

    abstract::In the present study, age- and calcium-related changes in the membrane fluidity of erythrocytes were examined in patients with essential hypertension by use of electron spin resonance method (ESR). The erythrocytes were obtained from patients with essential hypertension. We examined the ESR spectra for a fatty acid sp...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Tsuda K,Masuyama Y

    更新日期:1990-09-01 00:00:00

  • Angiotensin II potentiates the arterial pressure response to volume loading in humans.

    abstract::Angiotensin II (AII) has many potential effects on blood pressure regulation in addition to direct vasoconstriction. This study tested the hypothesis that minimally pressor infusions of AII, which themselves exert minimal effects on blood pressure, might significantly perturb the pressure response to hypertonic volume...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Goldsmith SR

    更新日期:1994-08-01 00:00:00

  • Blood pressure and angiotensin converting enzyme inhibitor use in hypertensive patients with chronic renal insufficiency.

    abstract:BACKGROUND:Hypertension treatment is important in managing chronic renal insufficiency (CRI). Little is known, however, about the blood pressure (BP) control achieved or the pattern of antihypertensive drug prescription among CRI patients. METHODS:Using computerized medical records, we studied 3,089 adult hypertensive...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Hsu CY,Bates DW,Kuperman GJ,Curhan GC

    更新日期:2001-12-01 00:00:00

  • Fibroblast Growth Factor-23, Heart Failure Risk, and Renin-Angiotensin-Aldosterone-System Blockade in Hypertension: The MESA Study.

    abstract:BACKGROUND:Higher fibroblast growth factor-23 (FGF23) concentrations have been found to be associated with incident heart failure (HF). Experimental data suggest FGF23 directly stimulates myocardial hypertrophy. FGF23 may also enhance renin-angiotensin-aldosterone system activity. Whether FGF23 is associated with incre...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,多中心研究


    authors: Akhabue E,Vu TT,Vaidya A,Michos ED,de Boer IH,Kestenbaum B,Allison M,Szklo M,Ouyang P,Yancy CW,Wolf M,Isakova T,Carnethon MR

    更新日期:2019-01-01 00:00:00

  • High-fructose feeding elicits insulin resistance without hypertension in normal mongrel dogs.

    abstract::This study was undertaken to characterize blood pressure (by continuous blood pressure recording), renal hemodynamics, and excretory function in high-fructose-fed insulin-resistant dogs. We fed 10 mongrel dogs for 28 days with a normal sodium diet containing 60% of the calories either as fructose (n = 6) or dextrose (...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Pamies-Andreu E,Fiksen-Olsen M,Rizza RA,Romero JC

    更新日期:1995-07-01 00:00:00

  • Gender-dependent differences in plasma leptin in essential hypertension.

    abstract::Leptin, the gene product of the ob gene, is influenced by gender and insulin sensitivity. Because in human hypertension there are important endocrine-hemodynamic gender-dependent differences, we compared plasma leptin in 39 essential hypertensives (EH) and in 27 normotensive healthy subjects (HS) matched for gender, a...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Mallamaci F,Cuzzola F,Tripepi G,Cutrupi S,Parlongo S,Tripepi R,Zoccali C

    更新日期:2000-08-01 00:00:00

  • Genetic Variation in SLC8A1 Gene Involved in Blood Pressure Responses to Acute Salt Loading.

    abstract:BACKGROUND:Salt sensitivity of blood pressure (SSBP) increases the risk of cardiovascular complications, and the heritability of SSBP is about 50% in Chinese population. However, studies identifying genes involved in BP responses to acute sodium loading and diuresis shrinkage are still limited. METHOD:A total of 342 e...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Liu K,Liu Z,Qi H,Liu B,Wu J,Liu Y,Zhang J,Cao H,Yan Y,He Y,Zhang L

    更新日期:2018-03-10 00:00:00

  • Oil and water? Economic advantage and biomedical progress do not mix well in a government guidelines committee.

    abstract::This article examines the results of the Joint National Committee's Fifth Report on the treatment of hypertension (JNC-V), especially regarding the economic arguments put forth therein. Economics are a poor basis for treatment decisions, as the cheapest therapies may not be the best for any given patient. Broad treatm...

    journal_title:American journal of hypertension

    pub_type: 杂志文章,评审


    authors: Ménard J

    更新日期:1994-10-01 00:00:00

  • Effect of doxazosin monotherapy on blood pressure and plasma lipids in patients with essential hypertension.

    abstract::The efficacy and safety of doxazosin (DOX) for the treatment of hypertension was investigated. A multicenter, double-blind, placebo-controlled, parallel design was employed. A 4-week placebo runin period was followed by a 9-week double-blind period during which patients were randomly assigned to placebo or 2, 4, or 8 ...

    journal_title:American journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Cubeddu LX,Pool JL,Bloomfield R,Klotman PE,Pickering BI,Wombolt DG,Nelson EB,Halperin A

    更新日期:1988-04-01 00:00:00

  • Twenty-Five-Year Changes in Office and Ambulatory Blood Pressure: Results from the Coronary Artery Risk Development in Young Adults (CARDIA) Study.

    abstract:BACKGROUND:Blood pressure (BP) measured in the office setting increases from early through later adulthood. However, it is unknown to what extent out-of-office BP derived via ambulatory BP monitoring (ABPM) increases over time, and which participant characteristics and risk factors might contribute to these increases. ...

    journal_title:American journal of hypertension

    pub_type: 杂志文章


    authors: Bundy JD,Jaeger BC,Huffman MD,Knox SS,Thomas SJ,Shimbo D,Booth Iii JN,Lewis CE,Edwards LJ,Schwartz JE,Muntner P

    更新日期:2020-11-17 00:00:00