abstract：:Coronavirus disease (COVID-19), a respiratory disease caused by a novel coronavirus designated severe acute respiratory syndrome coronavirus 2, has rapidly spread worldwide and has been recognized as a pandemic by the World Health Organization. Patients with altered immunologic function are at higher risk of acquiring...

journal_title：Journal of cutaneous medicine and surgery

authors： Ladda M,Lynde C,Fleming P

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Systemic therapy for atopic dermatitis (AD) has been challenging with limited safe and efficacious long-term treatment options. In 2017, dupilumab was approved in the United States, Europe, and Canada as the first targeted therapy for patients with moderate-to-severe AD. Despite promising efficacy and safety...

journal_title：Journal of cutaneous medicine and surgery

authors： Jo CE,Georgakopoulos JR,Ladda M,Ighani A,Mufti A,Drucker AM,Piguet V,Yeung J

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Indoor tanning (IT) in fitness facilities encourages a misleading positive relationship between tanning and health. While IT in Canadian fitness facilities has been studied, American literature regarding this topic is lacking. OBJECTIVES:The objective of this study is to evaluate availability, cost, reporte...

journal_title：Journal of cutaneous medicine and surgery

authors： Huang CM,Kirchhof MG

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Plaque psoriasis (PsO) is a chronic inflammatory disease that often presents at peak reproductive age in women of child-bearing potential (WOCBP). With the emergence of biologic therapies to treat PsO, guidance on disease management in WOCBP is needed to inform treatment decisions before, during, and after p...

journal_title：Journal of cutaneous medicine and surgery

authors： Yeung J,Gooderham MJ,Grewal P,Hong CH,Lansang P,Papp KA,Poulin Y,Turchin I,Vender R

更新日期：2020-07-01 00:00:00

abstract：:Genital ulcer disease can be caused by a wide variety of sources. Most commonly, genital ulcer disease is grouped into infectious and noninfectious causes. HSV, syphilis, lymphogranuloma venereum, and chancroid represent some common infectious ulcers. Noninfectious causes on the other hand can be inflammatory, noninfl...

journal_title：Journal of cutaneous medicine and surgery

authors： Maliyar K,Mufti A,Syed M,Selk A,Dutil M,Bunce PE,Alavi A

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Omalizumab is a third-line treatment for chronic spontaneous urticaria (CSU). Studies investigating the use of higher doses of omalizumab in patients unresponsive to regular doses are limited. OBJECTIVES:This study aims to investigate the effectiveness and safety of omalizumab 450 mg in CSU. METHODS:A retr...

journal_title：Journal of cutaneous medicine and surgery

authors： Salman A,Comert E

更新日期：2019-09-01 00:00:00

abstract：:Atopic dermatitis (AD) is the most common pediatric chronic inflammatory skin disease in North America, often involving complex treatment regimens and impairing the quality of life of affected children and their families. Two topical calcineurin inhibitors (TCIs) have been available for the treatment of AD in pediatri...

journal_title：Journal of cutaneous medicine and surgery

authors： Fiorillo L,Marcoux D,Ramien M

更新日期：2019-09-01 00:00:00

abstract：:We report a case of an 17-year-old male with a drug reaction in the spectrum of Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), triggered by carbamazepine, who was succesfully treated with the combination of dexamethasone, cyclosporine, and etanercept. This triple therapy halted and prevented skin epi...

journal_title：Journal of cutaneous medicine and surgery

authors： Coulombe J,Belzile E,Duhamel A,Rault P,Buteau C,DeBruycker JJ,Bussières JF

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:The onychodystrophies associated with Sézary syndrome (SzS) have rarely been described in the literature. We performed a retrospective analysis of SzS patients at a single institution and compared our data with previous publications. OBJECTIVES:The objectives of this study were to identify and describe the ...

journal_title：Journal of cutaneous medicine and surgery

authors： Damasco FM,Geskin LJ,Akilov OE

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:An eczema action plan (EAP) is an individualized tool to help caregivers and patients self-manage eczema. While novel illustrated EAPs have been developed and validated, there is limited literature examining the value of EAPs from patient and caregiver perspectives. OBJECTIVES:The objective of this study wa...

journal_title：Journal of cutaneous medicine and surgery

authors： Shelley AJ,McDonald KA,McEvoy A,Sauder M,Kanigsberg N,Zemek R,Vaillancourt R,Pouliot A,Ramien ML

更新日期：2018-11-01 00:00:00

abstract：:This document is a concise, current, and practical guide for dermatologists and other health care providers managing adult patients with moderate-to-severe atopic dermatitis (AD). The recommendations made here are based on a consensus of specialists with extensive experience managing patients with AD. Topics reviewed ...

journal_title：Journal of cutaneous medicine and surgery

authors： Hong CH,Gooderham MJ,Albrecht L,Bissonnette R,Dhadwal G,Gniadecki R,Grewal P,Kirchhof MG,Landells I,Lansang P,Lynde CW,Papp KA,Poulin Y,Sussman G,Turchin I,Wiseman M,Yeung J

更新日期：2018-11-01 00:00:00

abstract：:Juvenile xanthogranuloma (JXG) is a member of the non-Langerhans cell group of proliferative disorders of mononuclear phagocytes. JXG is a benign tumour of histiocytic cells. Classic JXG is divided into 2 main clinical subtypes: dome-shaped papules (<0.5 cm) and single/multiple nodules (<2.0 cm). A rare variant is ref...

journal_title：Journal of cutaneous medicine and surgery

authors： Ladha MA,Haber RM

更新日期：2018-09-01 00:00:00

abstract：:Sarcoidosis is a multisystem inflammatory condition of unknown etiology. Variability in the cutaneous features of sarcoidosis is profound, and its protean manifestations affirm the condition's designation as one of dermatology's "great mimics." Cutaneous phenotypes of sarcoidosis include but are by no means limited to...

journal_title：Journal of cutaneous medicine and surgery

authors： Hudson AD,Klimas NK,Stetson CL

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Diphenylcyclopropenone (DPCP) immunotherapy for viral warts has been used for many years, but no studies have analyzed the treatment effects of DPCP alone, without the use of conventional therapy before immunotherapy. OBJECTIVES:We evaluated clinical efficacy of DPCP monotherapy compared to cryotherapy and ...

journal_title：Journal of cutaneous medicine and surgery

authors： Park JY,Park BW,Cho EB,Park EJ,Kim KH,Kim KJ

更新日期：2018-05-01 00:00:00

abstract：:Lichen planus (LP) is a chronic inflammatory disorder that most commonly affects middle-aged individuals. LP involves the skin and/or mucous membranes, including oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. Linear LP, a rare distinct variant of LP, is characterised by pruritic eruption of lichen...

journal_title：Journal of cutaneous medicine and surgery

authors： Thomas MG,Betsy A

更新日期：2018-03-01 00:00:00

abstract：:Oral glucocorticoids are commonly used across every field of medicine; however, discontinuing them in patients can be challenging. The risk of acute adrenal crises secondary to glucocorticoid withdrawal can be fatal and arises from chronic suppression of the adrenal glands. Identifying risk factors for adrenal suppres...

journal_title：Journal of cutaneous medicine and surgery

authors： Nicholas MN,Li SK,Dytoc M

更新日期：2018-03-01 00:00:00

abstract：:Acne vulgaris, a condition that can affect people at any age, is the most common cause of referral to a dermatologist. Isotretinoin (ITT) is the most effective treatment available, but serious adverse effects, including a possible association with depression and suicide, limit its use. We review the current literature...

journal_title：Journal of cutaneous medicine and surgery

authors： Oliveira JM,Sobreira G,Velosa J,Telles Correia D,Filipe P

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:It has been postulated that periodic acid-Schiff staining of basement membrane can predict direct immunofluorescence patterns seen in epidermolysis bullosa acquisita and bullous pemphigoid. It has also been suggested that the type of inflammatory infiltrate or presence of fraying of basal keratinocytes may d...

journal_title：Journal of cutaneous medicine and surgery

authors： Gardner KM,Crawford RI

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Biologics have transformed the management of moderate to severe psoriasis. The persistency of biologics lacks real-world data. OBJECTIVES:To quantify drug survival of infliximab (IFX), adalimumab (ADA), etanercept (ETA), and ustekinumab (UST) and to identify potential factors affecting drug survival. METHO...

journal_title：Journal of cutaneous medicine and surgery

authors： Verma L,Mayba JN,Gooderham MJ,Verma A,Papp KA

更新日期：2018-01-01 00:00:00

abstract：:We present the extraordinary case of a 72-year-old man with a history of primary cutaneous peripheral T-cell lymphoma not otherwise specified (pcPTCL-NOS) previously controlled with topical agents who developed tumours in a sporotrichoid pattern. Culture of the tumours was negative, and histopathology showed findings ...

journal_title：Journal of cutaneous medicine and surgery

authors： Lewis DJ,Vin H,Hinojosa T,Tetzlaff MT,Dabaja BS,Duvic M

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder caused by loss-of-function mutation in the NF1 gene. Segmental or mosaic NF1 (MNF) is an uncommon presentation of the NF1 result of postzygotic mutations that present with subtle localised clinical findings. OBJECTIVES:Our study's objectives were t...

journal_title：Journal of cutaneous medicine and surgery

authors： Lara-Corrales I,Moazzami M,García-Romero MT,Pope E,Parkin P,Shugar A,Kannu P

更新日期：2017-09-01 00:00:00

abstract：:Basal cell carcinomas (BCC) are the most frequent tumours in humans and normally appear in photoexposed areas of the skin. It is widely accepted that BCCs originate at follicular stem cells and consequently are very rare in nonhairy areas. Here, we report 4 cases of vulvar BCC, 3 of which were located in a vulvar semi...

journal_title：Journal of cutaneous medicine and surgery

authors： García-de-la-Fuente MR,Santacana M,Vilardell F,Pujol RM,Gari E,Casanova JM

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Bullous pemphigoid (BP) is an autoimmune bullous disease requiring immunosuppressive therapy. Kaposi sarcoma (KS) is an angioproliferative tumor associated with the opportunistic viral infection human herpes virus 8 (HHV-8). It is a well-known condition associated with longstanding human immunodeficiency vir...

journal_title：Journal of cutaneous medicine and surgery

authors： Tremblay C,Friedmann D

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE), a rare acquired elastolytic disorder, occurs in postmenopausal, elderly women and is characterized by soft, white-yellow papules that localize on the neck and supraclavicular regions and often coalesce into cobblestone plaques. It has no s...

journal_title：Journal of cutaneous medicine and surgery

authors： Valbuena V,Assaad D,Yeung J

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Perforating dermatoses are a rare group of dermatologic conditions characterized by transepidermal elimination of dermal material that can be primary or acquired secondary to systemic disease. OBJECTIVE:We present an atypical case of perforating dermatosis resembling elastosis perforans serpiginosa (EPS) pr...

journal_title：Journal of cutaneous medicine and surgery

authors： Cloutier-Bosworth A,Naert K,Kirshen C

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Liquid nitrogen cryotherapy is a commonly used technique to treat a wide variety of dermatologic conditions including actinic keratoses, non-melanoma skin cancers, verrucae, and seborrheic keratoses. The risks associated with liquid nitrogen cryotherapy are important to know and discuss with patients prior t...

journal_title：Journal of cutaneous medicine and surgery

authors： Huang CM,Lu EY,Kirchhof MG

更新日期：2017-07-01 00:00:00

abstract：:The association between isotretinoin and atypical wound healing remains controversial. It is common practice to delay elective procedures for 6 to 24 months after oral isotretinoin therapy. The studies supporting common practices (SCP) recommend extending this period to include the 6 to 24 months preceding treatment. ...

journal_title：Journal of cutaneous medicine and surgery

authors： McDonald KA,Shelley AJ,Alavi A

更新日期：2017-07-01 00:00:00

abstract：:The Maintenance of Certification (MOC) Program administered by the Royal College of Physicians and Surgeons applies to all Fellows of the Royal College including dermatologists. It is mandatory for those who wish to maintain their fellowship in the Royal College and can be critical for maintaining licensure requiremen...

journal_title：Journal of cutaneous medicine and surgery

authors： Rich P

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Tumour size is a crucial factor used to plan Mohs procedures. Larger tumours require more time and stages of excision, and they need to be triaged as a higher priority. Therefore, the accuracy in measurement of tumour size is critical. OBJECTIVE:To investigate if there is a significant difference in accurac...

journal_title：Journal of cutaneous medicine and surgery

authors： To D,Macdonald J

更新日期：2017-05-01 00:00:00

abstract：:Atopic dermatitis is one of the most common skin disorders in the developed world, affecting up to 20% of children and 1% to 3% of adults. This review concisely explains the pathophysiology and epidemiology of atopic dermatitis, as well as potential challenges facing its successful treatment. Furthermore, mainstay top...

journal_title：Journal of cutaneous medicine and surgery

authors： Mayba JN,Gooderham MJ

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Dabrafenib, a novel selective small-molecule inhibitor of BRAF, has been shown to increase overall survival in patients with unresectable metastatic melanoma harboring the BRAF V600E mutation. The development of resistance has led to combination therapy with selective MEK inhibitor trametinib. Compared with ...

journal_title：Journal of cutaneous medicine and surgery

authors： Lacroix JP,Wang B

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Major advances have been made in the understanding of the pathophysiology of psoriasis. OBJECTIVES:The authors review the role of interleukin (IL) 17 in the pathogenesis of psoriasis and provide updates on approved and investigational therapies targeting IL-17 and the IL-17 receptor. METHODS:A PubMed searc...

journal_title：Journal of cutaneous medicine and surgery

authors： AbuHilal M,Walsh S,Shear N

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Acne affects a large proportion of the Canadian population and has psychosocial and financial consequences. OBJECTIVE:We provide cost information for treatments recommended by the Canadian acne guidelines. METHODS:Highest level recommendations were selected for 3-month usage cost. RESULTS:Three-month esti...

journal_title：Journal of cutaneous medicine and surgery

authors： Czilli T,Tan J,Knezevic S,Peters C

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Onychomycosis is a persistent fungal nail infection that is notoriously hard to treat. Approximately 20% to 25% of patients with onychomycosis do not respond to treatment, and 10% to 53% of patients relapse. As such, successful treatment is imperative for long-term disease management. OBJECTIVE:To identify ...

journal_title：Journal of cutaneous medicine and surgery

authors： Gupta AK,Cernea M,Foley KA

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Schnitzler syndrome (SS) is a rare autoinflammatory disorder characterized by a recurrent urticarial rash and a monoclonal immunoglobulin M gammopathy, as well as 2 of the following minor criteria: recurrent fever (>38°C), objective signs of abnormal bone remodeling, elevated C-reactive protein level or leuk...

journal_title：Journal of cutaneous medicine and surgery

authors： Urbanski M,Holfeld K,Milne A,Abbas M

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Darier's disease is an autosomal dominant genodermatosis typified by hyperkeratotic papules and plaques in a predominately seborrheic distribution. The vesiculo-bullous variant of Darier's disease is rare. Several previously reported cases have demonstrated clinical and microscopic features resembling famili...

journal_title：Journal of cutaneous medicine and surgery

authors： Klimas N,West C,Tarbox M

更新日期：2016-11-01 00:00:00

abstract：:Leprosy reactions are acute inflammatory episodes that occur in the setting of Mycobacterium leprae infection. Precipitants of reactions can be pharmacologic and nonpharmacologic. Both type 1 and type 2 reactions typically occur before and during leprosy treatment but may also occur after treatment has been completed....

journal_title：Journal of cutaneous medicine and surgery

authors： Wu J,Boggild AK

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Optimal aesthetic results are achieved when nasal defects after Mohs micrographic surgery (MMS) are reconstructed as entire nasal subunits. OBJECTIVE:To illustrate the importance of reconstructing the nose in entire subunits and explore the possibilities of expanding the principles of subunit reconstruction...

journal_title：Journal of cutaneous medicine and surgery

authors： Jergensen ZR,Pezeshk RA,Thornton JF

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Linear scleroderma, also known as "en coup de sabre," is a subtype of localized scleroderma that warrants aesthetic correction because it appears on the forehead region in children. OBJECTIVE:To report dermal fat grafting as a novel and effective surgical treatment option in linear scleroderma. METHODS:Und...

journal_title：Journal of cutaneous medicine and surgery

authors： Barin EZ,Cinal H,Cakmak MA,Tan O

更新日期：2016-05-01 00:00:00

abstract：:Psoriasis is a common inflammatory disease with significant comorbidities, whose management can be challenging given the variety of treatment options. It is critical for nurse practitioners, physician assistants, general practitioners, and dermatology trainees to have useful information about the treatment and monitor...

journal_title：Journal of cutaneous medicine and surgery

authors： Armstrong AW,Aldredge L,Yamauchi PS

更新日期：2016-05-01 00:00:00