Review of Atopic Dermatitis and Topical Therapies.

abstract：BACKGROUND:Naftifine is a topical allylamine that is effective and safe in the management of superficial dermatomycoses. Naftifine is fungicidal in vitro against a broad spectrum of dermatophyte fungi and provides good activity against Candida and Aspergillus species. It is also effective against gram-negative and gram...

journal_title：Journal of cutaneous medicine and surgery

authors： Gupta AK,Ryder JE,Cooper EA

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Granular parakeratosis is a hyperkeratotic eruption of unknown etiology that occurs in the axilla and other intertriginous areas. The histologic features are unique for the retention of keratohyalin granules in the stratum corneum. OBJECTIVE:The aim of the article is to review the clinical manifestations an...

journal_title：Journal of cutaneous medicine and surgery

authors： English JC 3rd,Derdeyn AS,Wilson WM,Patterson JW

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Encephalocraniocutaneous lipomatosis (ECCL) is a relatively new, nonhereditary, but congenital, neurocutaneous syndrome with unilateral cutaneous tumors and ipsilateral ophthalmologic and neurologic malformations. The syndrome is rare, with only 25 cases reported since first communication in 1970. The primar...

journal_title：Journal of cutaneous medicine and surgery

authors： Gawel J,Schwartz RA,Józwiak S

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Giant basal cell carcinomas (GBCC) can demonstrate very malignant behavior and pose a surgical challenge. OBJECTIVE:To present a surgical technique utilizing Mohs and the resection of narrow bands of tissue to excise a GBCC that created a large facial defect of 5 cm × 2 cm. METHODS:A unique combination of ...

journal_title：Journal of cutaneous medicine and surgery

authors： Nolan K,Henry M,Shohet M,Elahi E,Marmur E

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Major advances have been made in the understanding of the pathophysiology of psoriasis. OBJECTIVES:The authors review the role of interleukin (IL) 17 in the pathogenesis of psoriasis and provide updates on approved and investigational therapies targeting IL-17 and the IL-17 receptor. METHODS:A PubMed searc...

journal_title：Journal of cutaneous medicine and surgery

authors： AbuHilal M,Walsh S,Shear N

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The gtring presence of dermatology platforms on Facebook has been acknowledged; however, little is known about the extent to which different types of content influence the level of engagement with online users. OBJECTIVE:To assess the level of public engagement with different types of content posted on Face...

journal_title：Journal of cutaneous medicine and surgery

authors： Kim WB,Marinas JE,Vender RB

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Vemurafenib is an oral BRAF inhibitor recently approved for the treatment of metastatic melanoma. Patients treated with this medication have been reported to have the occurrence of squamous cell carcinoma (SCC) and/or actinic keratosis (AK). OBJECTIVE:We report the case of a patient treated with vemurafenib...

journal_title：Journal of cutaneous medicine and surgery

authors： Mays R,Curry J,Kim K,Tsai K,Arora A,Khan F,Ramirez-Fort M,Ciurea A

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Hybrid skin adnexal tumors are common, and spiradenocylindroma is well described. OBJECTIVE:However, malignant transformation in this setting is infrequent, especially resemblance to lymphoepithelioma-like carcinoma of skin, which is not associated with Epstein-Barr virus. METHODS:A 65-year-old female pres...

journal_title：Journal of cutaneous medicine and surgery

authors： Chetty R,Perez-Ordonez B,Gilbert R,Pagedar NA,Waldron J,Ghazarian D

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Molluscum contagiosum is a viral infection of the skin that is widely considered to be a self-resolving disease that can be treated with benign neglect. However, the clinical reality is that the disease can vary widely by anatomic site and by recalcitrance to treatment and remains a significant cause of morb...

journal_title：Journal of cutaneous medicine and surgery

authors： Nguyen HP,Franz E,Stiegel KR,Hsu S,Tyring SK

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Biologics have transformed the management of moderate to severe psoriasis. The persistency of biologics lacks real-world data. OBJECTIVES:To quantify drug survival of infliximab (IFX), adalimumab (ADA), etanercept (ETA), and ustekinumab (UST) and to identify potential factors affecting drug survival. METHO...

journal_title：Journal of cutaneous medicine and surgery

authors： Verma L,Mayba JN,Gooderham MJ,Verma A,Papp KA

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:It has been postulated that periodic acid-Schiff staining of basement membrane can predict direct immunofluorescence patterns seen in epidermolysis bullosa acquisita and bullous pemphigoid. It has also been suggested that the type of inflammatory infiltrate or presence of fraying of basal keratinocytes may d...

journal_title：Journal of cutaneous medicine and surgery

authors： Gardner KM,Crawford RI

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Schnitzler syndrome (SS) is a rare autoinflammatory disorder characterized by a recurrent urticarial rash and a monoclonal immunoglobulin M gammopathy, as well as 2 of the following minor criteria: recurrent fever (>38°C), objective signs of abnormal bone remodeling, elevated C-reactive protein level or leuk...

journal_title：Journal of cutaneous medicine and surgery

authors： Urbanski M,Holfeld K,Milne A,Abbas M

更新日期：2016-11-01 00:00:00

abstract：:We present the extraordinary case of a 72-year-old man with a history of primary cutaneous peripheral T-cell lymphoma not otherwise specified (pcPTCL-NOS) previously controlled with topical agents who developed tumours in a sporotrichoid pattern. Culture of the tumours was negative, and histopathology showed findings ...

journal_title：Journal of cutaneous medicine and surgery

authors： Lewis DJ,Vin H,Hinojosa T,Tetzlaff MT,Dabaja BS,Duvic M

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Forty-nine years ago the first complete and authoritative English text on the physiology and biochemistry of the skin was published by Stephen Rothman, an early basic researcher in dermatology. OBJECTIVE:The purpose of the article is to learn more about Stephen Rothman and his 1954 text, to learn more about...

journal_title：Journal of cutaneous medicine and surgery

authors： Jackson R

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:The use of photodynamic therapy (PDT) with topical aminolevulinic acid (ALA) on large skin surfaces has recently been reported for patients with multiple actinic keratoses. OBJECTIVE:The current study compared the ability of topical and systemic ALA-PDT as well as topical ALA-PDT with blue light to delay th...

journal_title：Journal of cutaneous medicine and surgery

authors： Liu Y,Viau G,Bissonnette R

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:We report a case of primary systemic amyloidosis in a 78-year-old Caucasian woman presented as a nonhealing ulcer on the right thigh for 3 months. Histopathology of the skin revealed widely thickened walls of middermal and subcutaneous vessels from deposition of amorphous eosinophilic material that stained p...

journal_title：Journal of cutaneous medicine and surgery

authors： Alhaddab M,Srolovitz H,Rosen N

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Emotional stress has been associated with the development of alopecia areata (AA) and androgenetic alopecia (AGA). Emotional intelligence (EI), a component of general intelligence, is thought to govern the recognition, expression, and control of stress and other emotions. People with low EI are unable to ade...

journal_title：Journal of cutaneous medicine and surgery

authors： Monselise A,Bar-On R,Chan L,Leibushor N,McElwee K,Shapiro J

更新日期：2013-01-01 00:00:00

abstract：:Juvenile xanthogranuloma (JXG) is a member of the non-Langerhans cell group of proliferative disorders of mononuclear phagocytes. JXG is a benign tumour of histiocytic cells. Classic JXG is divided into 2 main clinical subtypes: dome-shaped papules (<0.5 cm) and single/multiple nodules (<2.0 cm). A rare variant is ref...

journal_title：Journal of cutaneous medicine and surgery

authors： Ladha MA,Haber RM

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Plaque psoriasis (PsO) is a chronic inflammatory disease that often presents at peak reproductive age in women of child-bearing potential (WOCBP). With the emergence of biologic therapies to treat PsO, guidance on disease management in WOCBP is needed to inform treatment decisions before, during, and after p...

journal_title：Journal of cutaneous medicine and surgery

authors： Yeung J,Gooderham MJ,Grewal P,Hong CH,Lansang P,Papp KA,Poulin Y,Turchin I,Vender R

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Keratoelastoidosis marginalis is a rare disease that is a variant of solar elastosis. Long-term ultraviolet radiation exposure and chronic trauma secondary to manual labor are considered to be inciting factors. OBJECTIVE:To outline the clinical and histological features of this disorder. METHODS:We report ...

journal_title：Journal of cutaneous medicine and surgery

authors： Mengesha YM,Kayal JD,Swerlick RA

更新日期：2002-01-01 00:00:00

abstract：:Lichen planus (LP) is a chronic inflammatory disorder that most commonly affects middle-aged individuals. LP involves the skin and/or mucous membranes, including oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. Linear LP, a rare distinct variant of LP, is characterised by pruritic eruption of lichen...

journal_title：Journal of cutaneous medicine and surgery

authors： Thomas MG,Betsy A

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Although methotrexate is a highly effective treatment for psoriasis, nausea and vomiting may be dose-limiting side effects. Various approaches have been used to improve the tolerability of methotrexate therapy, including changing the dose or form of administration of the methotrexate or concomitant administr...

journal_title：Journal of cutaneous medicine and surgery

authors： Wilson JK,Phelps KC,Feldman SR

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Lichen planopilaris (LPP) is believed to be a follicular variant of lichen planus that affects pilosebaceous units, mainly of the scalp. An extremely rare variant of LPP is a linear form, which follows the lines of Blaschko. Of the five previously documented cases of linear LPP, all were limited to the face....

journal_title：Journal of cutaneous medicine and surgery

authors： Baker K,Pehr K

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The self-inflicted dermatoses such as acne excorieé and neurotic excoriations are often chronic, recurring, and resistant to standard dermatologic therapies. OBJECTIVE:We present a 28-year-old woman with longstanding acne excorieé, whose acne started at age 14 years and was followed by acne excorieé at age ...

journal_title：Journal of cutaneous medicine and surgery

authors： Gupta MA,Gupta AK

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Psoriasis in clinical trials is often measured by the Psoriasis Area and Severity Index (PASI). This measurement is well understood by clinical trialists and many dermatologists but rarely by patients and some clinicians. Patients may not understand their chance of improvement based on a PASI-50 or PASI-75 v...

journal_title：Journal of cutaneous medicine and surgery

authors： English PL,Vender R

更新日期：2008-11-01 00:00:00

abstract：:We report a case of an 17-year-old male with a drug reaction in the spectrum of Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), triggered by carbamazepine, who was succesfully treated with the combination of dexamethasone, cyclosporine, and etanercept. This triple therapy halted and prevented skin epi...

journal_title：Journal of cutaneous medicine and surgery

authors： Coulombe J,Belzile E,Duhamel A,Rault P,Buteau C,DeBruycker JJ,Bussières JF

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Informed shared decision making is a mutual process engaging both doctor and patient and informed by best medical evidence and patient values and preferences. OBJECTIVE:Our aim was to identify the needs of psoriasis patients in decisions on selecting treatment. METHODS:Psoriasis subjects participated in an...

journal_title：Journal of cutaneous medicine and surgery

authors： Tan J,Stacey D,Fung K,Barankin B,Bissonnette R,Gulliver W,Lui H,Shear N,Jackson C,Zhang X

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:The development of knowledge concerning the role of sun exposure in causing skin cancer has been a gradual one. OBJECTIVE:This article reviews the article by Urbach who used manikin coated with an ultraviolet dosimeter to see exactly where on the head and neck the exposure was greatest. CONCLUSION:Urbach s...

journal_title：Journal of cutaneous medicine and surgery

authors： Jackson R

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Cutaneous reactions to drugs are among the most common clinical manifestations of adverse drug events (ADEs); however, data on outpatient cutaneous adverse drug events (CADEs) are limited. PURPOSE:To provide national estimates of outpatient CADEs and determine their most frequent causes. METHODS:Outpatient...

journal_title：Journal of cutaneous medicine and surgery

authors： Koelblinger P,Dabade TS,Gustafson CJ,Davis SA,Yentzer BA,Kiracofe EA,Feldman SR

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Topical minoxidil solution (TMS) is widely used for androgenetic alopecia (AGA), and this is the first report of a large safety trial. OBJECTIVES:The aim of the study was to evaluate the safety profile of TMS by comparing hospitalization and death rates among subjects using TMS with controls. Cardiovascular...

journal_title：Journal of cutaneous medicine and surgery

authors： Shapiro J

更新日期：2003-07-01 00:00:00