Vulvar Basal Cell Carcinoma: Four Case Reports With Immunohistochemical Study.

Abstract:

:Basal cell carcinomas (BCC) are the most frequent tumours in humans and normally appear in photoexposed areas of the skin. It is widely accepted that BCCs originate at follicular stem cells and consequently are very rare in nonhairy areas. Here, we report 4 cases of vulvar BCC, 3 of which were located in a vulvar semimucous area, a nonphotoexposed area, and a nonhairy area. We have determined the CK7 and CK19 profile of all cases; both are markers of simple epithelium with glandular differentiation. Interestingly, all cases were positively stained for CK7 and CK19. Considering that the vulvar region is rich in sebaceous and apocrine units, we hypothesise a glandular origin of BCCs situated in the vulvar region.

journal_name

J Cutan Med Surg

authors

García-de-la-Fuente MR,Santacana M,Vilardell F,Pujol RM,Gari E,Casanova JM

doi

10.1177/1203475417712498

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

457-459

issue

5

eissn

1203-4754

issn

1615-7109

journal_volume

21

pub_type

杂志文章
  • Psoriasis comorbidities.

    abstract::Psoriasis has been associated with a number of behavioral and systemic comorbidities, including psoriatic arthritis, anxiety, depression, obesity, hypertension, diabetes mellitus, hyperlipidemia, metabolic syndrome, smoking, cardiovascular disease, alcoholism, Crohn's disease, lymphoma, and multiple sclerosis. Many of...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审

    doi:10.2310/7750.2009.00024

    authors: Guenther L,Gulliver W

    更新日期:2009-09-01 00:00:00

  • Management of Onychomycosis in Canada in 2014.

    abstract:BACKGROUND:Onychomycosis has several clinical presentations and is caused by various infectious organisms. OBJECTIVE:To provide guidance for selection of appropriate treatment. METHODS:The literature on onychomycosis management was reviewed to generate an evidence-based decision tree. RESULTS AND CONCLUSION:Several ...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审

    doi:10.2310/7750.2014.14090

    authors: Gupta AK,Paquet M

    更新日期:2015-05-01 00:00:00

  • Exacerbation of psoriasis under efalizumab therapy.

    abstract:BACKGROUND:Efalizumab is a recombinant humanized IgG1-kappa isotype monoclonal antibody that binds to CD11a, inhibiting T-cell activation. It has been approved for the treatment of moderate to severe plaque psoriasis. Efalizumab has been associated with the development of skin eruptions during the administration period...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.2310/7750.2008.07087

    authors: Rallis E,Verros C,Karanikola E,Valaskatzi A,Papaconstantis M

    更新日期:2009-03-01 00:00:00

  • Linear Lichen Planus: Continuum From Skin to Mucosa.

    abstract::Lichen planus (LP) is a chronic inflammatory disorder that most commonly affects middle-aged individuals. LP involves the skin and/or mucous membranes, including oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. Linear LP, a rare distinct variant of LP, is characterised by pruritic eruption of lichen...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.1177/1203475417733463

    authors: Thomas MG,Betsy A

    更新日期:2018-03-01 00:00:00

  • Epidermodysplasia verruciformis associated with myelodysplastic syndrome: an intriguing association.

    abstract:BACKGROUND:Epidermodysplasia verruciformis (EV) is a rare genodermatosis characterized by massive infection with human papillomaviruses (HPVs) and development of skin cancer. Myelodysplastic syndromes (MDSs) are a group of chronic conditions that involve dysplastic hematopoiesis, peripheral blood cytopenias, and a high...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.2310/7750.2009.08049

    authors: Oliveira WR,Ferreira GN,Rady PL,Festa C,Tyring SK

    更新日期:2009-11-01 00:00:00

  • Retrospective Review of Folliculitis Decalvans in 23 Patients with Course and Treatment Analysis of Long-standing Cases.

    abstract:BACKGROUND:To date, there is no standard treatment of folliculitis decalvans (FD), a rare type of cicatricial alopecia. OBJECTIVE AND METHODS:The records of 23 patients with FD (1998-2012) were retrospectively analyzed, with added data review on the course and treatment of long-standing cases. RESULTS:Initial managem...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:

    authors: Bunagan MJ,Banka N,Shapiro J

    更新日期:2014-10-01 00:00:00

  • Occurrence of plantar pustular psoriasis during treatment with infliximab.

    abstract:BACKGROUND:Pustular psoriasis is an uncommon form of psoriasis that often affects areas of the hands and feet. It typically manifests as small pustules that develop within erythematous areas of the palms and soles. Infliximab, a tumor necrosis factor inhibitor, can be used to treat pustular psoriasis. Infliximab can al...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.2310/7750.2008.07080

    authors: English PL,Vender R

    更新日期:2009-01-01 00:00:00

  • A clinical evaluation of tazarotene 0.1% gel, with and without a high- or mid-high-potency corticosteroid, in patients with stable plaque psoriasis.

    abstract:BACKGROUND:Several clinical trials have established the benefit of using a topical corticosteroid in conjunction with tazarotene gel in the treatment of plaque psoriasis. However, there is little information comparing the relative benefits of different corticosteroids, or different formulations of corticosteroids, when...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1007/s10227-001-0031-z

    authors: Green L,Sadoff W

    更新日期:2002-03-01 00:00:00

  • Safe psoriasis control: a new outcome measure for the composite assessment of the efficacy and safety of psoriasis treatment.

    abstract:BACKGROUND:PASI is an inadequate outcome measure for the assessment of psoriasis treatments. No currently used endpoints provide a benefit: risk assessment of treatment taking into consideration all available efficacy and safety data. OBJECTIVE:To propose a new outcome measure called "safe psoriasis control" (SPC), wh...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.1007/s10227-005-0121-4

    authors: Papp KA,Henninger E

    更新日期:2005-12-01 00:00:00

  • Non-melanoma Skin Cancer in Canada Chapter 5: Management of Squamous Cell Carcinoma.

    abstract:BACKGROUND:Squamous cell carcinoma (SCC) is the second-most common form of non-melanoma skin cancer (NMSC). OBJECTIVE:To provide guidance to Canadian health care practitioners regarding management of SCCs. METHODS:Literature searches and development of graded recommendations were carried out as discussed in the accom...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,实务指引

    doi:10.1177/1203475415582318

    authors: Sapijaszko M,Zloty D,Bourcier M,Poulin Y,Janiszewski P,Ashkenas J,Canadian Non-melanoma Skin Cancer Guidelines Committee.

    更新日期:2015-05-01 00:00:00

  • Favre-Racouchot syndrome in a 39-year old female following radiation therapy.

    abstract:BACKGROUND:Favre-Racouchot syndrome is a cutaneous disease characterized by nodules, cysts, and comedones that typically develops on sun-exposed areas of the face. This syndrome most commonly affects white males between the ages of 40 and 60 years and is frequently associated with chronic sun exposure and, more recentl...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.2310/7750.2013.13011

    authors: Sutherland AE,Green PJ

    更新日期:2014-01-01 00:00:00

  • Practical approach to the hormonal treatment of acne.

    abstract::Acne is a disease of the pilosebaceous units and these are mainly under hormonal control. In female patients, hormonal therapy is a unique opportunity for the treatment of acne. Several combined oral contraceptives (COCs), cyproterone acetate, spironolactone, flutamide, and others, have been tried for the control of a...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审

    doi:10.1007/s10227-004-0755-7

    authors: Poulin Y

    更新日期:2004-01-01 00:00:00

  • A Bullous Flare of a Hyperkeratotic Affair: A Case Report.

    abstract:BACKGROUND:Darier's disease is an autosomal dominant genodermatosis typified by hyperkeratotic papules and plaques in a predominately seborrheic distribution. The vesiculo-bullous variant of Darier's disease is rare. Several previously reported cases have demonstrated clinical and microscopic features resembling famili...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.1177/1203475416660295

    authors: Klimas N,West C,Tarbox M

    更新日期:2016-11-01 00:00:00

  • Contemporary Role of Topical Calcineurin Inhibitors: A Pediatric Dermatology Perspective.

    abstract::Atopic dermatitis (AD) is the most common pediatric chronic inflammatory skin disease in North America, often involving complex treatment regimens and impairing the quality of life of affected children and their families. Two topical calcineurin inhibitors (TCIs) have been available for the treatment of AD in pediatri...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审

    doi:10.1177/1203475419857975

    authors: Fiorillo L,Marcoux D,Ramien M

    更新日期:2019-09-01 00:00:00

  • Safety of topical minoxidil solution: a one-year, prospective, observational study.

    abstract:BACKGROUND:Topical minoxidil solution (TMS) is widely used for androgenetic alopecia (AGA), and this is the first report of a large safety trial. OBJECTIVES:The aim of the study was to evaluate the safety profile of TMS by comparing hospitalization and death rates among subjects using TMS with controls. Cardiovascular...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.1007/s10227-002-0121-6

    authors: Shapiro J

    更新日期:2003-07-01 00:00:00

  • Multiple cutaneous granular cell tumors: case report of a 19-year-old African American female.

    abstract:BACKGROUND AND OBJECTIVE:This is a somewhat rare case of a 19-year-old African American female with multiple cutaneous granular cell tumors. Granular cell tumors are of neural origin, except in rare cases, and are considered benign, with a low incidence of malignancy. The clinical presentation varies greatly, but these...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.2310/7750.2011.10088

    authors: Henry M,Perry A

    更新日期:2011-11-01 00:00:00

  • Malignant melanoma in a patient with oculocutaneous albinism.

    abstract:BACKGROUND:Sun-induced malignancies (basal cell and squamous cell carcinomas) are common in oculocutaneous albinism, however, the incidence of malignant melanoma is a topic of controversy. OBJECTIVE:We have reviewed the literature and report a case of a woman with oculocutaneous albinism with an amelanotic melanoma of...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.1177/120347540000400307

    authors: Streutker CJ,McCready D,Jimbow K,From L

    更新日期:2000-07-01 00:00:00

  • Purse-string suture for round and oval defects: a useful technique in dermatologic surgery.

    abstract:BACKGROUND:Round and oval skin wounds, like facial pigmented nevi after excision, are traditionally sutured linearly for closure, leaving significant scars, which greatly influences their appearance. OBJECTIVE:This article provides an overview of our experience using intradermal purse-string suture for round and oval ...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.1177/120347541201600104

    authors: Zhu JW,Wu XJ,Lu ZF,Cai SQ,Zheng M

    更新日期:2012-01-01 00:00:00

  • Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document. Section V: Consensus Statements on the Assessment and Management of Adult Patients With Moderate-to-Severe Atopic Dermatitis.

    abstract::This document is a concise, current, and practical guide for dermatologists and other health care providers managing adult patients with moderate-to-severe atopic dermatitis (AD). The recommendations made here are based on a consensus of specialists with extensive experience managing patients with AD. Topics reviewed ...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.1177/1203475418803625

    authors: Hong CH,Gooderham MJ,Albrecht L,Bissonnette R,Dhadwal G,Gniadecki R,Grewal P,Kirchhof MG,Landells I,Lansang P,Lynde CW,Papp KA,Poulin Y,Sussman G,Turchin I,Wiseman M,Yeung J

    更新日期:2018-11-01 00:00:00

  • Spectrum of dermoscopic patterns in lichen planus: a case series from China.

    abstract:BACKGROUND:Dermoscopy has been shown to be a promising method to facilitate the diagnosis of lichen planus (LP) outside of China. OBJECTIVE:To investigate the spectrum of dermoscopic patterns in Chinese LP patients. METHODS:The clinical data and dermoscopic patterns of nine LP cases with a total of 43 lesions were ev...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.2310/7750.2013.13049

    authors: Tan C,Min ZS,Xue Y,Zhu WY

    更新日期:2014-01-01 00:00:00

  • Nodular amyloidosis: case report and literature review.

    abstract:BACKGROUND:Amyloidosis refers to a group of depositional diseases that are classified into two main types: systemic and localized. Large nodules of localized cutaneous amyloidosis of the nasal ala and surrounding skin are rare and the treatment is often unsatisfactory. OBJECTIVE:We report a case of rapidly enlarging, ...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审

    doi:10.1007/BF02737862

    authors: Kakani RS,Goldstein AE,Meisher I,Hoffman C

    更新日期:2001-03-01 00:00:00

  • The Accuracy of Measurements of Nonmelanoma Skin Cancer Sizes Referred to the Mohs Surgery Clinic.

    abstract:BACKGROUND:Tumour size is a crucial factor used to plan Mohs procedures. Larger tumours require more time and stages of excision, and they need to be triaged as a higher priority. Therefore, the accuracy in measurement of tumour size is critical. OBJECTIVE:To investigate if there is a significant difference in accurac...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.1177/1203475416683391

    authors: To D,Macdonald J

    更新日期:2017-05-01 00:00:00

  • Use of transcutaneous nerve stimulation wristband to treat methotrexate-induced nausea.

    abstract:BACKGROUND:Although methotrexate is a highly effective treatment for psoriasis, nausea and vomiting may be dose-limiting side effects. Various approaches have been used to improve the tolerability of methotrexate therapy, including changing the dose or form of administration of the methotrexate or concomitant administr...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.1007/s10227-001-0146-2

    authors: Wilson JK,Phelps KC,Feldman SR

    更新日期:2002-11-01 00:00:00

  • The Role of IL-17 in the Pathogenesis of Psoriasis and Update on IL-17 Inhibitors for the Treatment of Plaque Psoriasis.

    abstract:BACKGROUND:Major advances have been made in the understanding of the pathophysiology of psoriasis. OBJECTIVES:The authors review the role of interleukin (IL) 17 in the pathogenesis of psoriasis and provide updates on approved and investigational therapies targeting IL-17 and the IL-17 receptor. METHODS:A PubMed searc...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审

    doi:10.1177/1203475416651605

    authors: AbuHilal M,Walsh S,Shear N

    更新日期:2016-11-01 00:00:00

  • An Approach to Minimising Risk of Adrenal Insufficiency When Discontinuing Oral Glucocorticoids.

    abstract::Oral glucocorticoids are commonly used across every field of medicine; however, discontinuing them in patients can be challenging. The risk of acute adrenal crises secondary to glucocorticoid withdrawal can be fatal and arises from chronic suppression of the adrenal glands. Identifying risk factors for adrenal suppres...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审

    doi:10.1177/1203475417736278

    authors: Nicholas MN,Li SK,Dytoc M

    更新日期:2018-03-01 00:00:00

  • Treatment decision needs of psoriasis patients: cross-sectional survey.

    abstract:BACKGROUND:Informed shared decision making is a mutual process engaging both doctor and patient and informed by best medical evidence and patient values and preferences. OBJECTIVE:Our aim was to identify the needs of psoriasis patients in decisions on selecting treatment. METHODS:Psoriasis subjects participated in an...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.2310/7750.2010.09049

    authors: Tan J,Stacey D,Fung K,Barankin B,Bissonnette R,Gulliver W,Lui H,Shear N,Jackson C,Zhang X

    更新日期:2010-09-01 00:00:00

  • Elastosis perforans serpignosa: treatment with liquid nitrogen cryotherapy and review of the literature.

    abstract:BACKGROUND:Elastosis perforans serpiginosa (EPS) is a rare skin disease in which abnormal elastic tissue fibers, other connective tissue elements, and cellular debris are expelled from the papillary dermis via transepithelial elimination. It is characterized by an eruption of small grouped hyperkeratotic papules in a s...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审

    doi:10.2310/7750.2009.08064

    authors: Humphrey S,Hemmati I,Randhawa R,Crawford RI,Hong CH

    更新日期:2010-01-01 00:00:00

  • Improving Cure Rates in Onychomycosis.

    abstract:BACKGROUND:Onychomycosis is a persistent fungal nail infection that is notoriously hard to treat. Approximately 20% to 25% of patients with onychomycosis do not respond to treatment, and 10% to 53% of patients relapse. As such, successful treatment is imperative for long-term disease management. OBJECTIVE:To identify ...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审

    doi:10.1177/1203475416653734

    authors: Gupta AK,Cernea M,Foley KA

    更新日期:2016-11-01 00:00:00

  • A Systematic Review on Oral Isotretinoin Therapy and Clinically Observable Wound Healing in Acne Patients.

    abstract::The association between isotretinoin and atypical wound healing remains controversial. It is common practice to delay elective procedures for 6 to 24 months after oral isotretinoin therapy. The studies supporting common practices (SCP) recommend extending this period to include the 6 to 24 months preceding treatment. ...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审

    doi:10.1177/1203475417701419

    authors: McDonald KA,Shelley AJ,Alavi A

    更新日期:2017-07-01 00:00:00

  • Modification of LC phenotype and suppression of contact hypersensitivity response by stress.

    abstract:BACKGROUND:Stress is thought to exacerbate a number of diseases, some of which are skin disorders. Epidermal Langerhans' cells play a major role in cutaneous immune reactions. OBJECTIVE:The effects of two types of stress on the cutaneous immune system were to be assessed in mice. METHODS:Mice received stress by immob...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章

    doi:10.1177/120347549800300205

    authors: Hosoi J,Tsuchiya T,Denda M,Ashida Y,Takashima A,Granstein RD,Koyama J

    更新日期:1998-10-01 00:00:00