Abstract:
BACKGROUND:Although methotrexate is a highly effective treatment for psoriasis, nausea and vomiting may be dose-limiting side effects. Various approaches have been used to improve the tolerability of methotrexate therapy, including changing the dose or form of administration of the methotrexate or concomitant administration of folic acid or an antiemetic. OBJECTIVE:The objective of this case report is to present the use of a novel, nonpharmacologic approach for controlling the nausea associated with methotrexate therapy. RESULTS:A 47-year-old patient with long-standing psoriasis was treated with methotrexate. She developed nausea refractory to standard antiemetic measures. She noted almost immediate relief of her nausea when using a transcutaneous nerve stimulation wristband. CONCLUSIONS:Nerve stimulation may be a valid alternative to other first-line antiemetic therapies.
journal_name
J Cutan Med Surgjournal_title
Journal of cutaneous medicine and surgeryauthors
Wilson JK,Phelps KC,Feldman SRdoi
10.1007/s10227-001-0146-2subject
Has Abstractpub_date
2002-11-01 00:00:00pages
551-3issue
6eissn
1203-4754issn
1615-7109journal_volume
6pub_type
杂志文章abstract:BACKGROUND:Epidermodysplasia verruciformis (EV) is a rare genodermatosis characterized by massive infection with human papillomaviruses (HPVs) and development of skin cancer. Myelodysplastic syndromes (MDSs) are a group of chronic conditions that involve dysplastic hematopoiesis, peripheral blood cytopenias, and a high...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.2310/7750.2009.08049
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:Diphenylcyclopropenone (DPCP) immunotherapy for viral warts has been used for many years, but no studies have analyzed the treatment effects of DPCP alone, without the use of conventional therapy before immunotherapy. OBJECTIVES:We evaluated clinical efficacy of DPCP monotherapy compared to cryotherapy and ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475418764106
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:The number of dermatology residency positions in Canada has not reflected the growing workforce shortage. Until 2005, all dermatology residents at the University of Ottawa were committed to return to their funding area at the completion of their training. This has left Eastern Ontario with a critical shortag...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.2310/7750.2008.07071
更新日期:2008-09-01 00:00:00
abstract::Acne vulgaris, a condition that can affect people at any age, is the most common cause of referral to a dermatologist. Isotretinoin (ITT) is the most effective treatment available, but serious adverse effects, including a possible association with depression and suicide, limit its use. We review the current literature...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1177/1203475417719052
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Omalizumab is a third-line treatment for chronic spontaneous urticaria (CSU). Studies investigating the use of higher doses of omalizumab in patients unresponsive to regular doses are limited. OBJECTIVES:This study aims to investigate the effectiveness and safety of omalizumab 450 mg in CSU. METHODS:A retr...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475419847956
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:A new treatment for actinic keratoses, ingenol mebutate, was recently approved by the US Food and Drug Administration. OBJECTIVE:To review the mechanisms of action, efficacy and safety data, and practical recommendations for ingenol mebutate. METHODS:The PubMed and clinicaltrials.gov databases were searche...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.2310/7750.2012.12050
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Linear scleroderma, also known as "en coup de sabre," is a subtype of localized scleroderma that warrants aesthetic correction because it appears on the forehead region in children. OBJECTIVE:To report dermal fat grafting as a novel and effective surgical treatment option in linear scleroderma. METHODS:Und...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475415624912
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Mast cells stimulate inflammation and itch sensation in the skin by releasing various mediators when they are activated. Stress exacerbates some skin diseases. We have reported that inhalation of certain odorants modulates immune reactions in the skin. OBJECTIVE:The possible usage of odorants in the regulat...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1007/s10227-002-0129-y
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:Pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE), a rare acquired elastolytic disorder, occurs in postmenopausal, elderly women and is characterized by soft, white-yellow papules that localize on the neck and supraclavicular regions and often coalesce into cobblestone plaques. It has no s...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475417699407
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:We report on a 42-year-old man with Stage IIA non-Hodgkin's lymphoma who developed a severe mucocutaneous blistering eruption. His diagnosis, paraneoplastic pemphigus, was based on clinical, histological, and immunofluorescence findings and confirmed by immunoprecipitation. Despite maximal ther...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1007/s10227-001-0130-x
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:Amyloidosis refers to a group of depositional diseases that are classified into two main types: systemic and localized. Large nodules of localized cutaneous amyloidosis of the nasal ala and surrounding skin are rare and the treatment is often unsatisfactory. OBJECTIVE:We report a case of rapidly enlarging, ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1007/BF02737862
更新日期:2001-03-01 00:00:00
abstract:BACKGROUND:Although betamethasone valerate (BMV) foam, 0.12% (Luxiq, Connectics Corporation, Palo Alto, CA) is approved by the Food and Drug Administration for the treatment of corticosteroid-responsive scalp dermatoses, no data are available for its use on nonscalp psoriasis. OBJECTIVE:We evaluated the safety and eff...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s10227-001-0006-0
更新日期:2001-07-01 00:00:00
abstract::Psoriasis is a T-cell mediated skin disease that affects approximately 2% of the population worldwide. Despite the prevalence of the disease and long-standing efforts to develop strategies to treat it, there is a need for safe and effective therapies to treat psoriasis, particularly the more severe forms. Biological a...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1007/s10227-006-0103-1
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Informed shared decision making is a mutual process engaging both doctor and patient and informed by best medical evidence and patient values and preferences. OBJECTIVE:Our aim was to identify the needs of psoriasis patients in decisions on selecting treatment. METHODS:Psoriasis subjects participated in an...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.2310/7750.2010.09049
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Sarcoidosis is a systemic granulomatous disease of unknown etiology that affects multiple organ systems, including the pulmonary, lymphatic, skeletal, and integumentary systems. Improved understanding of the intrinsic immunology and molecular biology in sarcoidosis can be applied to the treatment of this dis...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.2310/7750.2006.00063
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Local skin reactions are common during imiquimod treatment of actinic keratosis (AK). Cyclical application of imiquimod may improve tolerability while maintaining efficacy. OBJECTIVE:To assess the tolerability of imiquimod and clearance rate of AK lesions after imiquimod application. METHODS:Imiquimod 5% c...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.2310/7750.2008.07045
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:The onychodystrophies associated with Sézary syndrome (SzS) have rarely been described in the literature. We performed a retrospective analysis of SzS patients at a single institution and compared our data with previous publications. OBJECTIVES:The objectives of this study were to identify and describe the ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1177/1203475419839937
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Bullous pemphigoid (BP) is an autoimmune bullous disease requiring immunosuppressive therapy. Kaposi sarcoma (KS) is an angioproliferative tumor associated with the opportunistic viral infection human herpes virus 8 (HHV-8). It is a well-known condition associated with longstanding human immunodeficiency vir...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475417712247
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Bullous pemphigoid (BP) is an autoimmune polymorphic skin disease characterized by erythematous papules and plaques and tense bullae. A skin biopsy for direct immunofluorescence (DIF) is used to detect autoantibodies and complement proteins. OBJECTIVE:We sought to determine which location would provide the ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.2310/7750.2014.14004
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Any scientific discipline needs a sharply defined set of words for exact and reproducible communication. Surprisingly this has never been a strong point in dermatological science, especially as regards the living gross pathology of skin disease. OBJECTIVE:This article briefly reviews the four editions of a ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1007/s10227-001-0016-y
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Pustular psoriasis is an uncommon form of psoriasis that often affects areas of the hands and feet. It typically manifests as small pustules that develop within erythematous areas of the palms and soles. Infliximab, a tumor necrosis factor inhibitor, can be used to treat pustular psoriasis. Infliximab can al...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.2310/7750.2008.07080
更新日期:2009-01-01 00:00:00
abstract::The primary goal of treatment for external genital warts (EGWs) is to eradicate visible lesions and address symptoms that may accompany them, but it does not address the underlying virus. Left untreated, warts may grow, remain the same, or spontaneously regress as a result of being cleared by the immune system. Howeve...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:Liquid nitrogen cryotherapy is a commonly used technique to treat a wide variety of dermatologic conditions including actinic keratoses, non-melanoma skin cancers, verrucae, and seborrheic keratoses. The risks associated with liquid nitrogen cryotherapy are important to know and discuss with patients prior t...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475417702152
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Onychomycosis is a persistent fungal nail infection that is notoriously hard to treat. Approximately 20% to 25% of patients with onychomycosis do not respond to treatment, and 10% to 53% of patients relapse. As such, successful treatment is imperative for long-term disease management. OBJECTIVE:To identify ...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1177/1203475416653734
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Elastosis perforans serpiginosa (EPS) is a rare skin disease in which abnormal elastic tissue fibers, other connective tissue elements, and cellular debris are expelled from the papillary dermis via transepithelial elimination. It is characterized by an eruption of small grouped hyperkeratotic papules in a s...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.2310/7750.2009.08064
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Intralesional Candida antigen has been used as immunotherapy to treat refractory warts in the immunocompetent pediatric and adult populations but has not been reported in individuals with human immunodeficiency virus (HIV). PURPOSE:To examine if Candida antigen resulted in clearance of medically refractory,...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.2310/7750.2013.12112
更新日期:2013-09-01 00:00:00
abstract::Basal cell carcinomas (BCC) are the most frequent tumours in humans and normally appear in photoexposed areas of the skin. It is widely accepted that BCCs originate at follicular stem cells and consequently are very rare in nonhairy areas. Here, we report 4 cases of vulvar BCC, 3 of which were located in a vulvar semi...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475417712498
更新日期:2017-09-01 00:00:00
abstract::A renaissance is taking place in the field of wound healing. Interest in wounds has probably never been so great, and a number of key therapeutic advances in the last 2 or 3 years are only an indication of more progress to come. In large part, we are benefitting from decades of basic research that has provided the kno...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:Acne affects a large proportion of the Canadian population and has psychosocial and financial consequences. OBJECTIVE:We provide cost information for treatments recommended by the Canadian acne guidelines. METHODS:Highest level recommendations were selected for 3-month usage cost. RESULTS:Three-month esti...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1177/1203475416653735
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Genital herpes is a very common sexually transmitted disease. Safe and effective therapies are needed for patients with frequent recurrences. OBJECTIVE:The aim of our study was to determine the efficacy and safety of famciclovir for suppression of herpes simplex virus (HSV) infection in patients with histor...
journal_title:Journal of cutaneous medicine and surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s10227-002-0141-2
更新日期:2003-11-01 00:00:00